Upregulation of AMPK by 4-O-methylascochlorin promotes autophagy via the HIF-1α expression

AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms

(2016) Antero Salminen et al.   BIOGERONTOLOGY

Atg7 in AML: a double-edged sword?

(2016) S. Grant   BLOOD

LC3/GABARAP family proteins: autophagy-(un)related functions

(2016) Marco B. E. Schaaf et al.   FASEB JOURNAL

Anti-Inflammatory Effect of Ascochlorin in LPS-Stimulated RAW 264.7 Macrophage Cells Is Accompanied With the Down-Regulation of iNOS, COX-2 and Proinflammatory Cytokines Through NF-κB, ERK1/2, and p38 Signaling Pathway

(2016) Sook-Hyun Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism

(2016) LAN GUI et al.   Experimental and Therapeutic Medicine

Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1

(2016) Ji-Hong Moon et al.   Oncotarget

Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology

(2015) Beth Levine et al.   TRENDS IN CELL BIOLOGY

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

(2015) Yongjie Wei et al.   eLife

Autophagy: An emerging target for cancer therapy

(2014) Maria Høyer-Hansen et al.   Autophagy

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

(2014) Meghan B. Azad et al.   Autophagy

Hypoxia inducible factor-1 is involved in growth factor, glucocorticoid and hypoxia mediated regulation of vascular endothelial growth factor-A in human meningiomas

(2014) Y. Wu et al.   JOURNAL OF NEURO-ONCOLOGY

Coordination of autophagy with other cellular activities

(2013) Yan Wang et al.   ACTA PHARMACOLOGICA SINICA

Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines

(2013) Ming-Ju Hsieh et al.   ARCHIVES OF TOXICOLOGY

Dynamin 1-like-dependent mitochondrial fission initiates overactive mitophagy in the hepatotoxicity of cadmium

(2013) Huifeng Pi et al.   Autophagy

Hidden Behind Autophagy: The Unconventional Roles of ATG Proteins

(2013) Jovanka Bestebroer et al.   TRAFFIC

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy

(2012) Zhong-Qiu Yu et al.   Autophagy

4-O-Carboxymethyl Ascochlorin Causes ER Stress and Induced Autophagy in Human Hepatocellular Carcinoma Cells

(2012) Jeong Han Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

4-O-methylascochlorin, methylated derivative of ascochlorin, stabilizes HIF-1α via AMPK activation

(2011) Ji-Hak Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy

(2011) Yongchao Zhao et al.   MOLECULAR CELL

Image-based genome-wide siRNA screen identifies selective autophagy factors

(2011) Anthony Orvedahl et al.   NATURE

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

ATG12–ATG3 and mitochondria

(2010) Lilliana Radoshevich et al.   Autophagy

A quantitative assay for the monitoring of autophagosome accumulation in different phases of the cell cycle

(2010) Vitaliy Kaminskyy et al.   Autophagy

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Autophagy and cancer: Dynamism of the metabolism of tumor cells and tissues

(2008) Katsuya Tsuchihara et al.   CANCER LETTERS

Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L

(2008) I Papandreou et al.   CELL DEATH AND DIFFERENTIATION

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE