Tumor microenvironment based stimuli-responsive CRISPR/Cas delivery systems: A viable platform for interventional approaches
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Title
Tumor microenvironment based stimuli-responsive CRISPR/Cas delivery systems: A viable platform for interventional approaches
Authors
Keywords
Gene therapy, CRISPR/Cas, Stimuli-responsive delivery, Tumor microenvironment
Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 210, Issue -, Pages 112257
Publisher
Elsevier BV
Online
2021-12-02
DOI
10.1016/j.colsurfb.2021.112257
References
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Note: Only part of the references are listed.- Aptamer-based ATP-responsive delivery systems for cancer diagnosis and treatment
- (2021) Elham Sameiyan et al. Acta Biomaterialia
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- (2021) Qiang Yang et al. International Journal of Nanomedicine
- Targeting metastatic cancer
- (2021) Karuna Ganesh et al. NATURE MEDICINE
- CRISPR-dCas9-Guided and Telomerase-Responsive Nanosystem for Precise Anti-Cancer Drug Delivery
- (2021) Yingxin Ma et al. ACS Applied Materials & Interfaces
- Tumor Microenvironment Remodeling-Based Penetration Strategies to Amplify Nanodrug Accessibility to Tumor Parenchyma
- (2021) Yanhong Liu et al. ADVANCED DRUG DELIVERY REVIEWS
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects
- (2021) Lindomar J.C. Albuquerque et al. JOURNAL OF CONTROLLED RELEASE
- A Nucleic Acid/Gold Nanorod-Based Nanoplatform for Targeted Gene Editing and Combined Tumor Therapy
- (2021) Wantao Tang et al. ACS Applied Materials & Interfaces
- Charge-reversal nanocomolexes-based CRISPR/Cas9 delivery system for loss-of-function oncogene editing in hepatocellular carcinoma
- (2021) Jing-Jun Nie et al. JOURNAL OF CONTROLLED RELEASE
- Nano-delivery systems focused on tumor microenvironment regulation and biomimetic strategies for treatment of breast cancer metastasis
- (2021) Xiaoyan Gu et al. JOURNAL OF CONTROLLED RELEASE
- The Role of Tumor Necrosis Factor in Manipulating the Immunological Response of Tumor Microenvironment
- (2021) Dipranjan Laha et al. Frontiers in Immunology
- All‐In‐One Dendrimer‐Based Lipid Nanoparticles Enable Precise HDR‐Mediated Gene Editing In Vivo
- (2021) Lukas Farbiak et al. ADVANCED MATERIALS
- Sono‐Controllable and ROS‐Sensitive CRISPR‐Cas9 Genome Editing for Augmented/Synergistic Ultrasound Tumor Nanotherapy
- (2021) Yinying Pu et al. ADVANCED MATERIALS
- Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy
- (2021) Xueqing Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Efficient in vitro and in vivo docetaxel delivery mediated by pH-sensitive LPHNPs for effective breast cancer therapy
- (2021) Rajesh Singh Jadon et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- In vivo targeted delivery of nucleic acids and CRISPR genome editors enabled by GSH-responsive silica nanoparticles
- (2021) Yuyuan Wang et al. JOURNAL OF CONTROLLED RELEASE
- Reduction‐Sensitive Fluorinated‐Pt(IV) Universal Transfection Nanoplatform Facilitating CT45‐Targeted CRISPR/dCas9 Activation for Synergistic and Individualized Treatment of Ovarian Cancer
- (2021) Hongtong Lu et al. Small
- TNFα siRNA delivery by nanoparticles and photochemical internalization for psoriasis topical therapy
- (2021) Isabella Luiz Suzuki et al. JOURNAL OF CONTROLLED RELEASE
- Nano-puerarin regulates tumor microenvironment and facilitates chemo- and immunotherapy in murine triple negative breast cancer model
- (2020) Huan Xu et al. BIOMATERIALS
- Efficient CRISPR/Cas9 Gene-chemo Synergistic Cancer Therapy via a Stimuli-Responsive Chitosan-Based Nanocomplex Elicits Anti-Tumorigenic Pathway Effect
- (2020) Bingchen Zhang et al. CHEMICAL ENGINEERING JOURNAL
- A Multifunction Lipid-Based CRISPR-Cas13a Genetic Circuit Delivery System for Bladder Cancer Gene Therapy
- (2020) Jing Fan et al. ACS Synthetic Biology
- Reshaping Tumor Immune Microenvironment through Acidity-Responsive Nanoparticles Featured with CRISPR/Cas9-Mediated Programmed Death-Ligand 1 Attenuation and Chemotherapeutics-Induced Immunogenic Cell Death
- (2020) Kun Tu et al. ACS Applied Materials & Interfaces
- Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy
- (2020) Xiangrong Song et al. ADVANCED DRUG DELIVERY REVIEWS
- Aptamer/Peptide‐Functionalized Genome‐Editing System for Effective Immune Restoration through Reversal of PD‐L1‐Mediated Cancer Immunosuppression
- (2020) Xiao‐Yan He et al. ADVANCED MATERIALS
- CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation
- (2020) Wujin Sun et al. Science Advances
- Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy
- (2020) Tao Wan et al. JOURNAL OF CONTROLLED RELEASE
- Tumor microenvironment-induced structure changing drug/gene delivery system for overcoming delivery-associated challenges
- (2020) Min Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Tumor-responsive dynamic nanoassemblies for targeted imaging, therapy and microenvironment manipulation
- (2020) Liang Ee Low et al. JOURNAL OF CONTROLLED RELEASE
- A Lactose‐Derived CRISPR/Cas9 Delivery System for Efficient Genome Editing In Vivo to Treat Orthotopic Hepatocellular Carcinoma
- (2020) Yu Qi et al. Advanced Science
- Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects
- (2020) Shaohui Deng et al. Science Advances
- Non-viral strategies for delivering genome editing enzymes
- (2020) Jie Li et al. ADVANCED DRUG DELIVERY REVIEWS
- MicroRNA-responsive release of Cas9/sgRNA from DNA nanoflower for cytosolic protein delivery and enhanced genome editing
- (2020) Jinjin Shi et al. BIOMATERIALS
- CRISPR/Cas gene therapy
- (2020) Baohong Zhang JOURNAL OF CELLULAR PHYSIOLOGY
- Co-delivery of Sorafenib and CRISPR/Cas9 Based on Targeted Core–Shell Hollow Mesoporous Organosilica Nanoparticles for Synergistic HCC Therapy
- (2020) Bing-Chen Zhang et al. ACS Applied Materials & Interfaces
- MicroRNA replacement therapy in cancer
- (2019) Homa Mollaei et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Molecular landmarks of tumor hypoxia across cancer types
- (2019) Vinayak Bhandari et al. NATURE GENETICS
- CRISPR/Cas Systems towards Next-Generation Biosensing
- (2019) Yi Li et al. TRENDS IN BIOTECHNOLOGY
- Methodologies for Improving HDR Efficiency
- (2019) Mingjie Liu et al. Frontiers in Genetics
- Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
- (2019) Benjamin P. Kleinstiver et al. NATURE BIOTECHNOLOGY
- pH-Responsive Polymer Nanoparticles for Drug Delivery
- (2019) Nayeleh Deirram et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing
- (2019) Xiaoti Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Microenvironment-Responsive Delivery of the Cas9 RNA-Guided Endonuclease for Efficient Genome Editing
- (2019) Jun Yin et al. BIOCONJUGATE CHEMISTRY
- Delivery of Liver-Specific miRNA-122 Using a Targeted Macromolecular Prodrug toward Synergistic Therapy for Hepatocellular Carcinoma
- (2019) Qian Ning et al. ACS Applied Materials & Interfaces
- Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing
- (2019) Danny Wilbie et al. ACCOUNTS OF CHEMICAL RESEARCH
- Intelligent polymeric micelles for multidrug co-delivery and cancer therapy
- (2019) Guangping Yu et al. Artificial Cells Nanomedicine and Biotechnology
- A boronic acid–rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing
- (2019) Chongyi Liu et al. Science Advances
- Cdk5 knocking out mediated by CRISPR-Cas9 genome editing for PD-L1 attenuation and enhanced antitumor immunity
- (2019) Huan Deng et al. Acta Pharmaceutica Sinica B
- Hyaluronan-modified nanoparticles for tumor-targeting
- (2019) Yu Sakurai et al. Expert Opinion on Drug Delivery
- Enzyme responsive drug delivery systems in cancer treatment
- (2019) Mahsa Shahriari et al. JOURNAL OF CONTROLLED RELEASE
- A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing
- (2019) Guojun Chen et al. Nature Nanotechnology
- GSH-Activatable NIR Nanoplatform with Mitochondria Targeting for Enhancing Tumor-Specific Therapy
- (2019) Guoliang Yang et al. ACS Applied Materials & Interfaces
- Cell-Selective Messenger RNA Delivery and CRISPR/Cas9 Genome Editing by Modulating the Interface of Phenylboronic Acid-Derived Lipid Nanoparticles and Cellular Surface Sialic Acid
- (2019) Qiao Tang et al. ACS Applied Materials & Interfaces
- Dual‐Locking Nanoparticles Disrupt the PD‐1/PD‐L1 Pathway for Efficient Cancer Immunotherapy
- (2019) Zhanzhan Zhang et al. ADVANCED MATERIALS
- The Acidic Tumor Microenvironment as a Driver of Cancer
- (2019) Ebbe Boedtkjer et al. Annual Review of Physiology
- ROS-responsive “smart” polymeric conjugate: Synthesis, characterization and proof-of-concept study
- (2019) Natalia Oddone et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery
- (2019) Jianbing Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
- (2019) Josh Tycko et al. Nature Communications
- Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia
- (2019) Sateesh Krishnamurthy et al. Nature Communications
- Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
- (2019) Kira S. Makarova et al. NATURE REVIEWS MICROBIOLOGY
- Engineering of a Nanosized Biocatalyst for Combined Tumor Starvation and Low-Temperature Photothermal Therapy
- (2018) Jun Zhou et al. ACS Nano
- Unlockable Nanocomplexes with Self-Accelerating Nucleic Acid Release for Effective Staged Gene Therapy of Cardiovascular Diseases
- (2018) Jing-Jun Nie et al. ADVANCED MATERIALS
- Active Intracellular Delivery of a Cas9/sgRNA Complex Using Ultrasound-Propelled Nanomotors
- (2018) Malthe Hansen-Bruhn et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities
- (2018) Ling Li et al. BIOMATERIALS
- A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment
- (2018) Xiao Zhao et al. CANCER LETTERS
- Glutathione metabolism in cancer progression and treatment resistance
- (2018) Ankita Bansal et al. JOURNAL OF CELL BIOLOGY
- Effective PEI-mediated delivery of CRISPR-Cas9 complex for targeted gene therapy
- (2018) Nari Ryu et al. Nanomedicine-Nanotechnology Biology and Medicine
- CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
- (2018) Janice S. Chen et al. SCIENCE
- Gene Editing on Center Stage
- (2018) Rasmus O. Bak et al. TRENDS IN GENETICS
- Ionic-crosslinked polysaccharide/PEI/DNA nanoparticles for stabilized gene delivery
- (2018) Ying Zhang et al. CARBOHYDRATE POLYMERS
- Mitochondria-targeting single-layered graphene quantum dots with dual recognition sites for ATP imaging in living cells
- (2018) Jia Hui Liu et al. Nanoscale
- CRISPR-Cas guides the future of genetic engineering
- (2018) Gavin J. Knott et al. SCIENCE
- Fluorinated Acid-Labile Branched Hydroxyl-Rich Nanosystems for Flexible and Robust Delivery of Plasmids
- (2018) Yu Qi et al. Small
- Tumor-Acidity-Cleavable Maleic Acid Amide (TACMAA): A Powerful Tool for Designing Smart Nanoparticles To Overcome Delivery Barriers in Cancer Nanomedicine
- (2018) Jin-Zhi Du et al. ACCOUNTS OF CHEMICAL RESEARCH
- Tumor targeted genome editing mediated by a multi-functional gene vector for regulating cell behaviors
- (2018) Bo-Ya Liu et al. JOURNAL OF CONTROLLED RELEASE
- Potent Protein Delivery into Mammalian Cells via a Supercharged Polypeptide
- (2018) Jun Yin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo
- (2018) Qi Liu et al. Advanced Science
- Highly sensitive ratiometric fluorescent paper sensor for the urine assay of cancer
- (2018) Yingxin Ma et al. TALANTA
- Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework
- (2017) Shahad K. Alsaiari et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Functionalized Lipid–Polymer Hybrid Nanoparticles Mediated Codelivery of Methotrexate and Aceclofenac: A Synergistic Effect in Breast Cancer with Improved Pharmacokinetics Attributes
- (2017) Neeraj K. Garg et al. MOLECULAR PHARMACEUTICS
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- Engineered Cpf1 variants with altered PAM specificities
- (2017) Linyi Gao et al. NATURE BIOTECHNOLOGY
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- Nucleic acid detection with CRISPR-Cas13a/C2c2
- (2017) Jonathan S. Gootenberg et al. SCIENCE
- Stimuli-Responsive Polymeric Nanocarriers for Efficient Gene Delivery
- (2017) Yingqin Li et al. Topics in Current Chemistry
- Reactive oxygen species (ROS)-responsive nanomedicine for RNAi-based cancer therapy
- (2017) Yang Li et al. Nanoscale
- Redox-Sensitive Hydroxyethyl Starch–Doxorubicin Conjugate for Tumor Targeted Drug Delivery
- (2016) Hang Hu et al. ACS Applied Materials & Interfaces
- Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice
- (2016) Ling Li et al. ACS Nano
- Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
- (2016) Mahdi Karimi et al. CHEMICAL SOCIETY REVIEWS
- One-pot Synthesis of Metal–Organic Frameworks with Encapsulated Target Molecules and Their Applications for Controlled Drug Delivery
- (2016) Haoquan Zheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The ligand (s) anchored lipobrid nanoconstruct mediated delivery of methotrexate: an effective approach in breast cancer therapeutics
- (2016) Neeraj K. Garg et al. Nanomedicine-Nanotechnology Biology and Medicine
- The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
- (2016) Ines Fonfara et al. NATURE
- CRISPR gene-editing tested in a person for the first time
- (2016) David Cyranoski NATURE
- New CRISPR–Cas systems from uncultivated microbes
- (2016) David Burstein et al. NATURE
- Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
- (2016) Bernd Zetsche et al. NATURE BIOTECHNOLOGY
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
- (2016) Omar O. Abudayyeh et al. SCIENCE
- Pathophysiological Basis for the Formation of the Tumor Microenvironment
- (2016) Michael R. Horsman et al. Frontiers in Oncology
- Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing
- (2015) Wujin Sun et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
- (2015) Bernd Zetsche et al. CELL
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells
- (2014) Neus Feliu et al. ACS Nano
- Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells
- (2014) Yanrong Qian et al. CANCER LETTERS
- pH-Sensitive nano-systems for drug delivery in cancer therapy
- (2013) Juan Liu et al. BIOTECHNOLOGY ADVANCES
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
- (2013) Seung Woo Cho et al. NATURE BIOTECHNOLOGY
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- RNA-programmed genome editing in human cells
- (2013) Martin Jinek et al. eLife
- Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery
- (2012) Yiyan He et al. BIOMATERIALS
- RNA-guided genetic silencing systems in bacteria and archaea
- (2012) Blake Wiedenheft et al. NATURE
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine
- (2011) Sharif M. Shaheen et al. BIOMATERIALS
- Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
- (2010) Kai Kessenbrock et al. CELL
- OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
- (2010) Pedro P. Medina et al. NATURE
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