- Home
- Publications
- Publication Search
- Publication Details
Title
CRISPR/Cas gene therapy
Authors
Keywords
-
Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-09-22
DOI
10.1002/jcp.30064
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank
- (2020) Maarten H. Geurts et al. Cell Stem Cell
- The promise and challenge of therapeutic genome editing
- (2020) Jennifer A. Doudna NATURE
- Continuous evolution of SpCas9 variants compatible with non-G PAMs
- (2020) Shannon M. Miller et al. NATURE BIOTECHNOLOGY
- Programmable base editing of mutated TERT promoter inhibits brain tumour growth
- (2020) Xinjian Li et al. NATURE CELL BIOLOGY
- CRISPR-engineered T cells in patients with refractory cancer
- (2020) Edward A. Stadtmauer et al. SCIENCE
- Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair
- (2020) Kohdai Kitamoto et al. Scientific Reports
- Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons
- (2020) Tim Ahfeldt et al. Stem Cell Reports
- Targeting RLIP with CRISPR/Cas9 controls tumor growth
- (2020) Jyotsana Singhal et al. CARCINOGENESIS
- Identification of calcium and integrin‐binding protein 1 as a novel regulator of production of amyloid β peptide using CRISPR/Cas9‐based screening system
- (2020) Yung Wen Chiu et al. FASEB JOURNAL
- Generation of New Isogenic Models of Huntington’s Disease Using CRISPR-Cas9 Technology
- (2020) Magdalena Dabrowska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dual base editor catalyzes both cytosine and adenine base conversions in human cells
- (2020) Xiaohui Zhang et al. NATURE BIOTECHNOLOGY
- A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
- (2020) Julian Grünewald et al. NATURE BIOTECHNOLOGY
- Extinction of all infectious HIV in cell culture by the CRISPR-Cas12a system with only a single crRNA
- (2020) Zongliang Gao et al. NUCLEIC ACIDS RESEARCH
- Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
- (2020) Russell T. Walton et al. SCIENCE
- Generation of Dip2a homozygous knockout murine ES cell line IBMSe001-A-1 via CRISPR/Cas9 technology
- (2020) Mingze Yao et al. Stem Cell Research
- SpRY: Engineered CRISPR/Cas9 Harnesses New Genome-Editing Power
- (2020) Dangquan Zhang et al. TRENDS IN GENETICS
- Ocular delivery of CRISPR/Cas genome editing components for treatment of eye diseases
- (2020) Wenhan Yu et al. ADVANCED DRUG DELIVERY REVIEWS
- Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies
- (2020) Devikala Gurusamy et al. CANCER CELL
- Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning
- (2020) Mandana Arbab et al. CELL
- PDGFRβ plays an essential role in patient vitreous-stimulated contraction of retinal pigment epithelial cells from epiretinal membranes
- (2020) Yanhui Yang et al. EXPERIMENTAL EYE RESEARCH
- Publisher Correction: Base editors for simultaneous introduction of C-to-T and A-to-G mutations
- (2020) Rina C. Sakata et al. NATURE BIOTECHNOLOGY
- Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations
- (2020) Oana M. Enache et al. NATURE GENETICS
- Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing
- (2020) Allison Knupp et al. Cell Reports
- Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia
- (2020) Seyedeh Zeinab Mirjalili Mohanna et al. Molecular Therapy-Methods & Clinical Development
- CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs
- (2020) Matthew A. Coelho et al. Nature Communications
- Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection
- (2019) Yulia Lampi et al. Scientific Reports
- CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations
- (2019) Grégoire Cullot et al. Nature Communications
- Identification of preexisting adaptive immunity to Cas9 proteins in humans
- (2019) Carsten T. Charlesworth et al. NATURE MEDICINE
- ApoE4: an emerging therapeutic target for Alzheimer’s disease
- (2019) Mirna Safieh et al. BMC Medicine
- Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease
- (2019) Anil R. Wadhwani et al. ANNALS OF NEUROLOGY
- Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
- (2019) Fiona M. Behan et al. NATURE
- Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes
- (2019) Shayesteh R. Ferdosi et al. Nature Communications
- CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice
- (2019) Qiaoqiao Xiao et al. Retrovirology
- CRISPR-Cas9-mediated genome editing increases lifespan and improves motor deficits in a Huntington’s disease mouse model
- (2019) Freja K. Ekman et al. Molecular Therapy-Nucleic Acids
- CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway
- (2019) Shuhua Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients
- (2019) Neil T. Sullivan et al. Scientific Reports
- Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
- (2019) Kira S. Makarova et al. NATURE REVIEWS MICROBIOLOGY
- Generation of a DAPK1 knockout first (conditional ready) human embryonic stem cell line (ZSSYe001-A) by CRISPR-Cas9 technology
- (2019) Cancan Xu et al. Stem Cell Research
- Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3
- (2018) Alexandra C. Chadwick et al. CIRCULATION
- Towards gene-editing treatment for alzheimer's disease: ApoE4 allele-specific knockout using a CRISPR cas9 variant
- (2018) D. Offen et al. CYTOTHERAPY
- CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells
- (2018) Yan Teng et al. GENES AND IMMUNITY
- Targeting mutantKRASwith CRISPR-Cas9 controls tumor growth
- (2018) Wonjoo Kim et al. GENOME RESEARCH
- CRISPR/Cas9-mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV-positive hepatocellular carcinoma cells
- (2018) Jia Song et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
- (2018) Seuk-Min Ryu et al. NATURE BIOTECHNOLOGY
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
- (2018) Robert J. Ihry et al. NATURE MEDICINE
- CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
- (2018) Emma Haapaniemi et al. NATURE MEDICINE
- Highly efficient RNA-guided base editing in rabbit
- (2018) Zhiquan Liu et al. Nature Communications
- Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
- (2018) Zhen Liu et al. Nature Communications
- The CRISPR tool kit for genome editing and beyond
- (2018) Mazhar Adli Nature Communications
- HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies
- (2018) Shuai Liu et al. Scientific Reports
- Large deletions induced by Cas9 cleavage
- (2018) Fatwa Adikusuma et al. NATURE
- Engineered CRISPR-Cas9 nuclease with expanded targeting space
- (2018) Hiroshi Nishimasu et al. SCIENCE
- Selective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cells
- (2018) Wookjae Lee et al. Scientific Reports
- Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants
- (2018) Lei Yang et al. Protein & Cell
- High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
- (2018) Dimitrios L. Wagner et al. NATURE MEDICINE
- Base editing: precision chemistry on the genome and transcriptome of living cells
- (2018) Holly A. Rees et al. NATURE REVIEWS GENETICS
- Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection
- (2018) Alexander G. Allen et al. Frontiers in Microbiology
- Potential Application of MicroRNA Profiling to the Diagnosis and Prognosis of HIV-1 Infection
- (2018) Bin Su et al. Frontiers in Microbiology
- Efficient RNA-guided base editing for disease modeling in pigs
- (2018) Zhifang Li et al. Cell Discovery
- Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery
- (2017) Serena G Giannelli et al. HUMAN MOLECULAR GENETICS
- CRISPR-Cas9 Mediated Gene-Silencing of the Mutant Huntingtin Gene in an In Vitro Model of Huntington’s Disease
- (2017) Nivya Kolli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington’s disease
- (2017) Su Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo
- (2017) Lei Xu et al. MOLECULAR THERAPY
- CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo
- (2017) Alex Mas Monteys et al. MOLECULAR THERAPY
- In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
- (2017) Chaoran Yin et al. MOLECULAR THERAPY
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Cardiovascular endocrinology: Is ANGPTL3 the next PCSK9?
- (2017) Kiran Musunuru et al. Nature Reviews Endocrinology
- Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression
- (2017) Taeyoung Koo et al. NUCLEIC ACIDS RESEARCH
- Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
- (2017) Holly A. Rees et al. Nature Communications
- Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9
- (2017) Joanna M. Feehan et al. Scientific Reports
- CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice
- (2017) Yongzhen Liu et al. Scientific Reports
- Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection
- (2017) Zhepeng Liu et al. Cell and Bioscience
- CRISPR-Cas9 Targeting ofPCSK9in Human Hepatocytes In Vivo—Brief ReportSignificance
- (2016) Xiao Wang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT SyndromeNovelty and Significance
- (2016) Worawan B. Limpitikul et al. CIRCULATION RESEARCH
- Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study
- (2016) R Kaminski et al. GENE THERAPY
- In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa
- (2016) Benjamin Bakondi et al. MOLECULAR THERAPY
- CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
- (2016) Daniel P. Dever et al. NATURE
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- A multifunctional AAV–CRISPR–Cas9 and its host response
- (2016) Wei Leong Chew et al. NATURE METHODS
- Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
- (2016) F. Jiang et al. SCIENCE
- CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape
- (2016) Zhen Wang et al. Cell Reports
- In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina
- (2016) Maria Carmela Latella et al. Molecular Therapy-Nucleic Acids
- Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing
- (2016) Rafal Kaminski et al. Scientific Reports
- High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
- (2015) Traver Hart et al. CELL
- Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition
- (2015) Nathalie Bergeron et al. CIRCULATION
- Engineered CRISPR-Cas9 nucleases with altered PAM specificities
- (2015) Benjamin P. Kleinstiver et al. NATURE
- Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
- (2015) Junwei Shi et al. NATURE BIOTECHNOLOGY
- ClinVar: public archive of interpretations of clinically relevant variants
- (2015) Melissa J. Landrum et al. NUCLEIC ACIDS RESEARCH
- The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA
- (2015) Weijun Zhu et al. Retrovirology
- Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection
- (2015) Panpan Hou et al. Scientific Reports
- Huntington disease
- (2015) Gillian P. Bates et al. Nature Reviews Disease Primers
- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
- (2014) Randall J. Platt et al. CELL
- Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
- (2014) Hiroshi Nishimasu et al. CELL
- Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing
- (2014) Qiurong Ding et al. CIRCULATION RESEARCH
- In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
- (2014) Danilo Maddalo et al. NATURE
- CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection
- (2014) Weiming Wang et al. PLoS One
- RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
- (2014) W. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
- (2013) Hirotaka Ebina et al. Scientific Reports
- Detection of group A Streptococcus in tonsils from pediatric patients reveals high rate of asymptomatic streptococcal carriage
- (2012) Amity L Roberts et al. BMC Pediatrics
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Retinitis pigmentosa in Spain
- (2010) C. Ayuso et al. CLINICAL GENETICS
- The cell biology of vision
- (2010) Ching-Hwa Sung et al. JOURNAL OF CELL BIOLOGY
- Exome Sequencing,ANGPTL3Mutations, and Familial Combined Hypolipidemia
- (2010) Kiran Musunuru et al. NEW ENGLAND JOURNAL OF MEDICINE
- RDX Induces Aberrant Expression of MicroRNAs in Mouse Brain and Liver
- (2008) Baohong Zhang et al. ENVIRONMENTAL HEALTH PERSPECTIVES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started