Reactive oxygen species (ROS)-responsive nanomedicine for RNAi-based cancer therapy

Cationic switchable lipids: pH-triggered molecular switch for siRNA delivery

(2017) W. Viricel et al.   Nanoscale

Redox-Activatable ATP-Depleting Micelles with Dual Modulation Characteristics for Multidrug-Resistant Cancer Therapy

(2017) Hebin Wang et al.   Advanced Healthcare Materials

Stimuli-Responsive Programmed Specific Targeting in Nanomedicine

(2016) Sheng Wang et al.   ACS Nano

A Fluorinated Bola-Amphiphilic Dendrimer for On-Demand Delivery of siRNA, via Specific Response to Reactive Oxygen Species

(2016) Xiaoxuan Liu et al.   ADVANCED FUNCTIONAL MATERIALS

Physical, Chemical, and Biological Structures based on ROS-Sensitive Moieties that are Able to Respond to Oxidative Microenvironments

(2016) Christos Tapeinos et al.   ADVANCED MATERIALS

Esterase-Activated Charge-Reversal Polymer for Fibroblast-Exempt Cancer Gene Therapy

(2016) Nasha Qiu et al.   ADVANCED MATERIALS

A novel cationic lipid with intrinsic antitumor activity to facilitate gene therapy of TRAIL DNA

(2016) Cong Luo et al.   BIOMATERIALS

CXCR4-targeted modular peptide carriers for efficient anti-VEGF siRNA delivery

(2016) Anna Egorova et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells

(2016) Zhengyu Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System

(2016) Xiuwen Guan et al.   NANO LETTERS

Targeted Co-delivery of PTX and TR3 siRNA by PTP Peptide Modified Dendrimer for the Treatment of Pancreatic Cancer

(2016) Yang Li et al.   Small

Novel miR-122 delivery system based on MS2 virus like particle surface displaying cell-penetrating peptide TAT for hepatocellular carcinoma

(2016) Guojing Wang et al.   Oncotarget

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

Structure-Invertible Nanoparticles for Triggered Co-Delivery of Nucleic Acids and Hydrophobic Drugs for Combination Cancer Therapy

(2015) Kai Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery

(2015) Xin Liu et al.   ADVANCED MATERIALS

Dendrimeric siRNA for Efficient Gene Silencing

(2015) Cheol Am Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enhanced therapeutic neovascularization by CD31-expressing cells and embryonic stem cell-derived endothelial cells engineered with chitosan hydrogel containing VEGF-releasing microtubes

(2015) Sangho Lee et al.   BIOMATERIALS

Self-assembled nanoscale coordination polymers carrying siRNAs and cisplatin for effective treatment of resistant ovarian cancer

(2015) Chunbai He et al.   BIOMATERIALS

Ultra-sensitive ROS-responsive tellurium-containing polymers

(2015) Wei Cao et al.   CHEMICAL COMMUNICATIONS

Correlation between expression and significance of δ-catenin, CD31, and VEGF of non-small cell lung cancer

(2015) X.L. Liu et al.   GENETICS AND MOLECULAR RESEARCH

Self-assembled nanoscale coordination polymers carrying oxaliplatin and gemcitabine for synergistic combination therapy of pancreatic cancer

(2015) Christopher Poon et al.   JOURNAL OF CONTROLLED RELEASE

Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery

(2015) Chun-Yang Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Collaborative Assembly Strategy for Tumor-Targeted siRNA Delivery

(2015) Qiong Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen peroxide-responsive anticancer hyperbranched polymer micelles for enhanced cell apoptosis

(2015) Bing Liu et al.   Polymer Chemistry

Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance

(2015) Tuo Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coadministration of Vascular Disrupting Agents and Nanomedicines to Eradicate Tumors from Peripheral and Central Regions

(2015) Wantong Song et al.   Small

Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs

(2014) Qihang Sun et al.   ADVANCED MATERIALS

Adaptive Amphiphilic Dendrimer-Based Nanoassemblies as Robust and Versatile siRNA Delivery Systems

(2014) Xiaoxuan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New directions in the design of phenylboronate-functionalized polymers for diagnostic and therapeutic applications

(2014) Akira Matsumoto et al.   POLYMER JOURNAL

ATP-triggered anticancer drug delivery

(2014) Ran Mo et al.   Nature Communications

ROS-cleavable proline oligomer crosslinking of polycaprolactone for pro-angiogenic host response

(2014) Sue Hyun Lee et al.   Journal of Materials Chemistry B

Oxidation-responsive polymers for biomedical applications

(2014) Cheng-Cheng Song et al.   Journal of Materials Chemistry B

A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells

(2013) Min Suk Shim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Therapeutic Nanocarriers with Hydrogen Peroxide-Triggered Drug Release for Cancer Treatment

(2013) Jinyao Liu et al.   BIOMACROMOLECULES

Anti-angiogenesis in cancer therapy: Hercules and hydra

(2013) S. Bellou et al.   CANCER LETTERS

Acid-Degradable Polymer-Caged Lipoplex (PCL) Platform for siRNA Delivery: Facile Cellular Triggered Release of siRNA

(2013) Bong Jin Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effective Tumor Treatment by VEGF siRNA Complexed with Hydrophobic Poly(Amino Acid)-Modified Polyethylenimine

(2013) Jie Chen et al.   MACROMOLECULAR BIOSCIENCE

Dye/Peroxalate Aggregated Nanoparticles with Enhanced and Tunable Chemiluminescence for Biomedical Imaging of Hydrogen Peroxide

(2012) Yong-Deok Lee et al.   ACS Nano

A Phenylboronate-Functionalized Polyion Complex Micelle for ATP-Triggered Release of siRNA

(2012) Mitsuru Naito et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycopolypeptides with a Redox-Triggered Helix-to-Coil Transition

(2012) Jessica R. Kramer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyphosphonium Polymers for siRNA Delivery: An Efficient and Nontoxic Alternative to Polyammonium Carriers

(2012) Cátia Ornelas-Megiatto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery

(2012) Erlei Jin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides

(2011) Ikuhiko Nakase et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemiluminescence-Generating Nanoreactor Formulation for Near-Infrared Imaging of Hydrogen Peroxide and Glucose Level in vivo

(2010) Chang-Keun Lim et al.   ADVANCED FUNCTIONAL MATERIALS

A Biocompatible Oxidation-Triggered Carrier Polymer with Potential in Therapeutics

(2010) Kyle E. Broaders et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

(2010) G. C. Van de Bittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-based systemic delivery of siRNA

(2009) Yu-Cheng Tseng et al.   ADVANCED DRUG DELIVERY REVIEWS

RNA Interference: From Basic Research to Therapeutic Applications

(2009) Jens Kurreck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY