Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

DhITACT: DNA Hydrogel Formation by Isothermal Amplification of Complementary Target in Fluidic Channels

(2015) Ho Yeon Lee et al.   ADVANCED MATERIALS

Dendrimeric siRNA for Efficient Gene Silencing

(2015) Cheol Am Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo genome editing using Staphylococcus aureus Cas9

(2015) F. Ann Ran et al.   NATURE

A split-Cas9 architecture for inducible genome editing and transcription modulation

(2015) Bernd Zetsche et al.   NATURE BIOTECHNOLOGY

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

Engineering DNA scaffolds for delivery of anticancer therapeutics

(2015) Wujin Sun et al.   Biomaterials Science

DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery

(2014) Rong Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine

(2014) M. Monsur Ali et al.   CHEMICAL SOCIETY REVIEWS

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA

(2014) S. Ramakrishna et al.   GENOME RESEARCH

Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

(2014) Wujin Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

(2014) John A Zuris et al.   NATURE BIOTECHNOLOGY

Engineering adeno-associated viruses for clinical gene therapy

(2014) Melissa A. Kotterman et al.   NATURE REVIEWS GENETICS

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Importance of the DNA “bond” in programmable nanoparticle crystallization

(2014) Robert J. Macfarlane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

ATP-triggered anticancer drug delivery

(2014) Ran Mo et al.   Nature Communications

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

(2013) Vikram Pattanayak et al.   NATURE BIOTECHNOLOGY

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease

(2013) Wataru Fujii et al.   NUCLEIC ACIDS RESEARCH

Antibody Therapeutics in Cancer

(2013) M. X. Sliwkowski et al.   SCIENCE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

A simple and rapid nonviral approach to efficiently transfect primary tissue–derived cells using polyethylenimine

(2012) Charlie Yu Ming Hsu et al.   Nature Protocols

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Tailoring nanocarriers for intracellular protein delivery

(2011) Zhen Gu et al.   CHEMICAL SOCIETY REVIEWS

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE