Sono‐Controllable and ROS‐Sensitive CRISPR‐Cas9 Genome Editing for Augmented/Synergistic Ultrasound Tumor Nanotherapy

Reprogramming the Tumor Microenvironment through Second‐Near‐Infrared‐Window Photothermal Genome Editing of PD‐L1 Mediated by Supramolecular Gold Nanorods for Enhanced Cancer Immunotherapy

(2021) Honglin Tang et al.   ADVANCED MATERIALS

Activating drugs with sound: Mechanisms behind sonodynamic therapy and the role of nanomedicine

(2020) Victor Choi et al.   BIOCONJUGATE CHEMISTRY

Near-infrared optogenetic engineering of photothermal nanoCRISPR for programmable genome editing

(2020) Xiaohong Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatiotemporal Delivery of CRISPR/Cas9 Genome Editing Machinery Using Stimuli‐Responsive Vehicles

(2020) Ming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy

(2020) Xianwen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects

(2020) Shaohui Deng et al.   Science Advances

Near-Infrared Light Irradiation Induced Mild Hyperthermia Enhances Glutathione Depletion and DNA Interstrand Cross-Link Formation for Efficient Chemotherapy

(2020) Jimei Zhang et al.   ACS Nano

Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy

(2020) Shuang Liang et al.   ADVANCED MATERIALS

Reactive Oxygen Species (ROS)-Responsive Prodrugs, Probes, and Theranostic Prodrugs: Applications in the ROS-Related Diseases

(2020) Pengfei Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Energy‐Converting Nanomedicine

(2019) Huijing Xiang et al.   Small

Adeno-associated virus vector as a platform for gene therapy delivery

(2019) Dan Wang et al.   NATURE REVIEWS DRUG DISCOVERY

Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing

(2019) Xiaoti Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-Responsive Prodrug-Based Supramolecular Nanosystems for Site-Specific Combination Therapy of Cancer

(2019) Soo Zeng Fiona Phua et al.   CHEMISTRY OF MATERIALS

Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

(2019) Yongchun Pan et al.   Science Advances

Triple-Targeting Delivery of CRISPR/Cas9 to Reduce the Risk of Cardiovascular Diseases

(2019) Lingmin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

State of the Art and Prospects in Metal–Organic Framework (MOF)-Based and MOF-Derived Nanocatalysis

(2019) Qi Wang et al.   CHEMICAL REVIEWS

Augment of Oxidative Damage with Enhanced Photodynamic Process and MTH1 Inhibition for Tumor Therapy

(2019) Jing-Jing Hu et al.   NANO LETTERS

Metal–Organic‐Framework‐Derived Carbon Nanostructures for Site‐Specific Dual‐Modality Photothermal/Photodynamic Thrombus Therapy

(2019) Fengrong Zhang et al.   Advanced Science

A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing

(2019) Guojun Chen et al.   Nature Nanotechnology

Nanoscale Covalent Organic Framework for Combinatorial Antitumor Photodynamic and Photothermal Therapy

(2019) Qun Guan et al.   ACS Nano

A Photolabile Semiconducting Polymer Nanotransducer for Near-Infrared Regulation of CRISPR/Cas9 Gene Editing

(2019) Yan Lyu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Responsive Mesoporous Silica Nanoparticle Platform for Magnetic Resonance Imaging-Guided High-Intensity Focused Ultrasound-Stimulated Cargo Delivery with Controllable Location, Time, and Dose

(2019) Chi-An Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery

(2019) Jianbing Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy

(2019) Jee-Yeon Ryu et al.   BIOMATERIALS

Nanozyme Decorated Metal–Organic Frameworks for Enhanced Photodynamic Therapy

(2018) Yan Zhang et al.   ACS Nano

Tumor targeting via EPR: Strategies to enhance patient responses

(2018) Susanne K. Golombek et al.   ADVANCED DRUG DELIVERY REVIEWS

Metal-Organic-Framework-Derived Carbon Nanostructure Augmented Sonodynamic Cancer Therapy

(2018) Xueting Pan et al.   ADVANCED MATERIALS

Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy

(2018) Peng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enhanced Cytosolic Delivery and Release of CRISPR/Cas9 by Black Phosphorus Nanosheets for Genome Editing

(2018) Wenhua Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Active Intracellular Delivery of a Cas9/sgRNA Complex Using Ultrasound-Propelled Nanomotors

(2018) Malthe Hansen-Bruhn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo

(2018) Qi Liu et al.   Advanced Science

Spatial control of in vivo CRISPR–Cas9 genome editing via nanomagnets

(2018) Haibao Zhu et al.   Nature Biomedical Engineering

Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework

(2017) Shahad K. Alsaiari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metalloporphyrin-Encapsulated Biodegradable Nanosystems for Highly Efficient Magnetic Resonance Imaging-Guided Sonodynamic Cancer Therapy

(2017) Ping Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancing Selective Photooxidation through Co–Nx-doped Carbon Materials as Singlet Oxygen Photosensitizers

(2017) Wenting Wu et al.   ACS Catalysis

Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

(2016) Xiaoqin Qian et al.   ADVANCED MATERIALS

Microfluidic Cell Deformability Assay for Rapid and Efficient Kinase Screening with the CRISPR-Cas9 System

(2016) Xin Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanomedicine Applications of Hybrid Nanomaterials Built from Metal–Ligand Coordination Bonds: Nanoscale Metal–Organic Frameworks and Nanoscale Coordination Polymers

(2015) Chunbai He et al.   CHEMICAL REVIEWS

CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation

(2015) X. Han et al.   Science Advances

Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing

(2014) Qiurong Ding et al.   CIRCULATION RESEARCH

Cellular Levels of 8-Oxoguanine in either DNA or the Nucleotide Pool Play Pivotal Roles in Carcinogenesis and Survival of Cancer Cells

(2014) Yusaku Nakabeppu   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

(2014) Kilian V. M. Huber et al.   NATURE

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

(2014) Helge Gad et al.   NATURE

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

(2008) Sugako Oka et al.   EMBO JOURNAL

Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death

(2007) Junji Ichikawa et al.   DNA REPAIR