Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy

Engineering adeno-associated virus vectors for gene therapy

(2020) Chengwen Li et al.   NATURE REVIEWS GENETICS

Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system

(2020) Yu Zhang et al.   Science Advances

Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing

(2020) Tuo Wei et al.   ACS Nano

A Noncovalent Fluorescence Turn-on Strategy for Hypoxia Imaging

(2019) Dong-Sheng Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo neuronal gene editing via CRISPR–Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer’s disease

(2019) Hanseul Park et al.   NATURE NEUROSCIENCE

A Hypoxia‐Responsive Albumin‐Based Nanosystem for Deep Tumor Penetration and Excellent Therapeutic Efficacy

(2019) Guangbao Yang et al.   ADVANCED MATERIALS

Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

(2019) Yongchun Pan et al.   Science Advances

Triple-Targeting Delivery of CRISPR/Cas9 to Reduce the Risk of Cardiovascular Diseases

(2019) Lingmin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Targeting‐Mediated Mild‐Temperature Photothermal Therapy with a Smart Albumin‐Based Nanodrug

(2019) Ge Gao et al.   Small

Hypoxia-Activated PEGylated Conditional Aptamer/Antibody for Cancer Imaging with Improved Specificity

(2019) Fang Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy

(2018) Peng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide

(2018) Hong-Xia Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-destructible polysaccharide nanocomposites with unlockable Au nanorods for high-performance photothermal therapy

(2018) Lizhi Song et al.   NPG Asia Materials

Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy

(2018) Caixia Huang et al.   Journal of Materials Chemistry B

Dual-stimuli responsive and reversibly activatable theranostic nanoprobe for precision tumor-targeting and fluorescence-guided photothermal therapy

(2017) Xu Zhao et al.   Nature Communications

Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA

(2016) Jason B. Miller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression

(2016) M Zou et al.   ONCOGENE

Cas9, poised for DNA cleavage

(2016) H. Chen et al.   SCIENCE

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Making the cut

(2015) J. Travis   SCIENCE

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Engineering adeno-associated viruses for clinical gene therapy

(2014) Melissa A. Kotterman et al.   NATURE REVIEWS GENETICS

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Development of Azo-Based Fluorescent Probes to Detect Different Levels of Hypoxia

(2013) Wen Piao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bimodal optical diagnostics of oral cancer based on Rose Bengal conjugated gold nanorod platform

(2013) Jia-Hong Wang et al.   BIOMATERIALS

Comparative transfection of DNA into primary and transformed mammalian cells from different lineages

(2010) Rosalie Maurisse et al.   BMC BIOTECHNOLOGY