Microfluidic models of the human circulatory system: versatile platforms for exploring mechanobiology and disease modeling
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Microfluidic models of the human circulatory system: versatile platforms for exploring mechanobiology and disease modeling
Authors
Keywords
-
Journal
Biophysical Reviews
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-07-15
DOI
10.1007/s12551-021-00815-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning
- (2020) Åsa K Hedman et al. HEART
- Heart-on-a-chip Model with Integrated Extra- and Intra-cellular Bioelectronics for Monitoring Cardiac Electrophysiology under Acute Hypoxia
- (2020) Haitao Liu et al. NANO LETTERS
- Microtubules regulate cardiomyocyte transversal Young’s modulus
- (2020) Pamela Swiatlowska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
- (2020) Xiaojun Chen et al. Micromachines
- Robotic fluidic coupling and interrogation of multiple vascularized organ chips
- (2020) Richard Novak et al. Nature Biomedical Engineering
- Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
- (2020) Anna Herland et al. Nature Biomedical Engineering
- TAVI Represents an Anti-Inflammatory Therapy via Reduction of Shear Stress Induced, Piezo-1-Mediated Monocyte Activation
- (2020) Sara Baratchi et al. CIRCULATION
- Environmentally controlled magnetic nano-tweezer for living cells and extracellular matrices
- (2020) Christian Aermes et al. Scientific Reports
- Platelet thrombus formation by upstream activation and downstream adhesion of platelets in a microfluidic system
- (2020) Sihui Xu et al. BIOSENSORS & BIOELECTRONICS
- Analyzing the shear‐induced sensitization of mechanosensitive ion channel Piezo‐1 in human aortic endothelial cells
- (2020) Austin Lai et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The cellular mechanobiology of aging: from biology to mechanics
- (2020) Apratim Bajpai et al. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
- Wearable sensors: At the frontier of personalised health monitoring, smart prosthetics and assistive technologies
- (2020) Farnaz Khoshmanesh et al. BIOSENSORS & BIOELECTRONICS
- Ultrathin Dual-Scale Nano- and Microporous Membranes for Vascular Transmigration Models
- (2019) Alec T. Salminen et al. Small
- Indoor nanoscale particulate matter-induced coagulation abnormality based on a human 3D microvascular model on a microfluidic chip
- (2019) Yan Li et al. JOURNAL OF NANOBIOTECHNOLOGY
- Renal reabsorption in 3D vascularized proximal tubule models
- (2019) Neil Y. C. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A cell lines derived microfluidic liver model for investigation of hepatotoxicity induced by drug-drug interaction
- (2019) Jiu Deng et al. Biomicrofluidics
- Inertial Microfluidics with Integrated Vortex Generators Using Liquid Metal Droplets as Fugitive Ink
- (2019) Ngan Nguyen et al. ADVANCED FUNCTIONAL MATERIALS
- Microfabricated blood vessels for modeling the vascular transport barrier
- (2019) William J. Polacheck et al. Nature Protocols
- Multivascular networks and functional intravascular topologies within biocompatible hydrogels
- (2019) Bagrat Grigoryan et al. SCIENCE
- 3D bioprinting of collagen to rebuild components of the human heart
- (2019) A. Lee et al. SCIENCE
- On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships
- (2019) Christopher W. McAleer et al. Scientific Reports
- Innovative Tools for Mechanobiology: Unraveling Outside-In and Inside-Out Mechanotransduction
- (2019) Danahe Mohammed et al. Frontiers in Bioengineering and Biotechnology
- A Microfluidic System for Studying the Effects of Disturbed Flow on Endothelial Cells
- (2019) Francisco Tovar-Lopez et al. Frontiers in Bioengineering and Biotechnology
- Studying the Response of Aortic Endothelial Cells under Pulsatile Flow Using a Compact Microfluidic System
- (2019) Mokhaled Mohammed et al. ANALYTICAL CHEMISTRY
- Integrating Flexible Electrochemical Sensor into Microfluidic Chip for Simulating and Monitoring Vascular Mechanotransduction
- (2019) Zi‐He Jin et al. Small
- Reconfigurable, Self-Sufficient Convective Heat Exchanger for Temperature Control of Microfluidic Systems
- (2019) Jiu Yang Zhu et al. ANALYTICAL CHEMISTRY
- Modular microfluidic systems cast from 3D-printed molds for imaging leukocyte adherence to differentially treated endothelial cultures
- (2019) Rodrigo Hernández Vera et al. Scientific Reports
- Bioprinting a 3D vascular construct for engineering a vessel-on-a-chip
- (2019) Mieradilijiang Abudupataer et al. BIOMEDICAL MICRODEVICES
- “Connecting worlds – a view on microfluidics for a wider application”
- (2018) Ana C. Fernandes et al. BIOTECHNOLOGY ADVANCES
- Translational models of tumor angiogenesis: A nexus of in silico and in vitro models
- (2018) Shirin Soleimani et al. BIOTECHNOLOGY ADVANCES
- Machine learning in cardiovascular medicine: are we there yet?
- (2018) Khader Shameer et al. HEART
- Liquid metal-based amalgamation-assisted lithography for fabrication of complex channels with diverse structures and configurations
- (2018) Sheng Yan et al. LAB ON A CHIP
- Flow dynamics control endothelial permeability in a microfluidic vessel bifurcation model
- (2018) Ehsan Akbari et al. LAB ON A CHIP
- A biomimetic microfluidic model to study signalling between endothelial and vascular smooth muscle cells under hemodynamic conditions
- (2018) Nicole C. A. van Engeland et al. LAB ON A CHIP
- High-precision modular microfluidics by micromilling of interlocking injection-molded blocks
- (2018) Crystal E. Owens et al. LAB ON A CHIP
- Elastomeric microvalve geometry affects haemocompatibility
- (2018) Crispin Szydzik et al. LAB ON A CHIP
- Real-time observation of leukocyte–endothelium interactions in tissue-engineered blood vessel
- (2018) Z. Chen et al. LAB ON A CHIP
- UniChip enables long-term recirculating unidirectional perfusion with gravity-driven flow for microphysiological systems
- (2018) Ying I. Wang et al. LAB ON A CHIP
- Current and future antiplatelet therapies: emphasis on preserving haemostasis
- (2018) James D. McFadyen et al. Nature Reviews Cardiology
- Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip
- (2018) Sasan Jalili-Firoozinezhad et al. Cell Death & Disease
- “Do-it-in-classroom” fabrication of microfluidic systems by replica moulding of pasta structures
- (2018) Ngan Nguyen et al. Biomicrofluidics
- A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX
- (2018) Xiang Li et al. LAB ON A CHIP
- A self-sufficient pressure pump using latex balloons for microfluidic applications
- (2018) Peter Thurgood et al. LAB ON A CHIP
- Intestinal Villi Model with Blood Capillaries Fabricated Using Collagen-Based Bioink and Dual-Cell-Printing Process
- (2018) WonJin Kim et al. ACS Applied Materials & Interfaces
- The effects of particle size, shape, density and flow characteristics on particle margination to vascular walls in cardiovascular diseases
- (2017) Hang T. Ta et al. Expert Opinion on Drug Delivery
- The Aging Cardiovascular System
- (2017) Francesco Paneni et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Micro-engineered perfusable 3D vasculatures for cardiovascular diseases
- (2017) Nishanth Venugopal Menon et al. LAB ON A CHIP
- Modeling angiogenesis with micro- and nanotechnology
- (2017) Li-Jiun Chen et al. LAB ON A CHIP
- “Open-top” microfluidic device for in vitro three-dimensional capillary beds
- (2017) Soojung Oh et al. LAB ON A CHIP
- Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data
- (2017) Pedro F. Costa et al. LAB ON A CHIP
- On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics
- (2017) Michelle B Chen et al. Nature Protocols
- Modeling Physiological Events in 2D vs. 3D Cell Culture
- (2017) Kayla Duval et al. PHYSIOLOGY
- Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model
- (2017) João Ribas et al. Small
- Molecular Sensors of Blood Flow in Endothelial Cells
- (2017) Sara Baratchi et al. TRENDS IN MOLECULAR MEDICINE
- A microfluidic model of the blood–brain barrier to study permeabilization by pulsed electric fields
- (2017) M. Bonakdar et al. RSC Advances
- An Electromagnetically Actuated Double-Sided Cell-Stretching Device for Mechanobiology Research
- (2017) Harshad Kamble et al. Micromachines
- A microfluidic renal proximal tubule with active reabsorptive function
- (2017) Else M. Vedula et al. PLoS One
- Microvasculature on a chip: study of the Endothelial Surface Layer and the flow structure of Red Blood Cells
- (2017) Daria Tsvirkun et al. Scientific Reports
- A microengineered model of RBC transfusion-induced pulmonary vascular injury
- (2017) Jeongyun Seo et al. Scientific Reports
- Detection of frequency-dependent endothelial response to oscillatory shear stress using a microfluidic transcellular monitor
- (2017) Yoshitaka J. Sei et al. Scientific Reports
- A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes
- (2017) Seokyoung Bang et al. Scientific Reports
- Three-dimensional biomimetic model to reconstitute sprouting lymphangiogenesis in vitro
- (2016) Sudong Kim et al. BIOMATERIALS
- Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip
- (2016) Yu Shrike Zhang et al. BIOMATERIALS
- Biomimetic channel modeling local vascular dynamics of pro-inflammatory endothelial changes
- (2016) Antony Thomas et al. Biomicrofluidics
- Direct quantification of transendothelial electrical resistance in organs-on-chips
- (2016) Marinke W. van der Helm et al. BIOSENSORS & BIOELECTRONICS
- Heart-on-a-chip based on stem cell biology
- (2016) Elzbieta Jastrzebska et al. BIOSENSORS & BIOELECTRONICS
- Advances in microfluidics in combating infectious diseases
- (2016) Andy Tay et al. BIOTECHNOLOGY ADVANCES
- Prevascularization in tissue engineering: Current concepts and future directions
- (2016) Matthias W. Laschke et al. BIOTECHNOLOGY ADVANCES
- Cell-microenvironment interactions and architectures in microvascular systems
- (2016) Simone Bersini et al. BIOTECHNOLOGY ADVANCES
- Large animal models of cardiovascular disease
- (2016) H. G. Tsang et al. CELL BIOCHEMISTRY AND FUNCTION
- Platelet signaling: a complex interplay between inhibitory and activatory networks
- (2016) A. P. Bye et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues
- (2016) Anna Marsano et al. LAB ON A CHIP
- 3D cardiac μtissues within a microfluidic device with real-time contractile stress readout
- (2016) Aereas Aung et al. LAB ON A CHIP
- Interstitial flow regulates the angiogenic response and phenotype of endothelial cells in a 3D culture model
- (2016) Sudong Kim et al. LAB ON A CHIP
- 3D printing of liquid metals as fugitive inks for fabrication of 3D microfluidic channels
- (2016) Dishit P. Parekh et al. LAB ON A CHIP
- Three-dimensional bioprinting of thick vascularized tissues
- (2016) David B. Kolesky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Early-Stage Atherosclerosis Research Model Based on Microfluidics
- (2016) Wenfu Zheng et al. Small
- Sub-cellular modeling of platelet transport in blood flow through microchannels with constriction
- (2016) Alireza Yazdani et al. Soft Matter
- A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
- (2016) Abhishek Jain et al. Nature Communications
- Endothelial cell alignment as a result of anisotropic strain and flow induced shear stress combinations
- (2016) Ravi Sinha et al. Scientific Reports
- Platelet Activation: The Mechanisms and Potential Biomarkers
- (2016) Seong-Hoon Yun et al. Biomed Research International
- Disturbed flow mediated modulation of shear forces on endothelial plane: A proposed model for studying endothelium around atherosclerotic plaques
- (2016) Uma Maheswari Balaguru et al. Scientific Reports
- 3D microtumors in vitro supported by perfused vascular networks
- (2016) Agua Sobrino et al. Scientific Reports
- Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes After Acute Myocardial Infarction
- (2015) Sang-Ging Ong et al. CIRCULATION
- A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs
- (2015) Choong Kim et al. LAB ON A CHIP
- Flow-driven assembly of VWF fibres and webs in in vitro microvessels
- (2015) Ying Zheng et al. Nature Communications
- Microfluidic-assisted cyclic mechanical stimulation affects cellular membrane integrity in a human muscular dystrophy in vitro model
- (2015) F. Michielin et al. RSC Advances
- “Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions”
- (2015) Robert G. Mannino et al. Scientific Reports
- Cardiovascular imaging: what have we learned from animal models?
- (2015) Arnoldo Santos et al. Frontiers in Pharmacology
- Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
- (2015) Anurag Mathur et al. Scientific Reports
- 3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs
- (2014) David B. Kolesky et al. ADVANCED MATERIALS
- Examination of the role of transient receptor potential vanilloid type 4 in endothelial responses to shear forces
- (2014) Sara Baratchi et al. Biomicrofluidics
- A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation
- (2014) Hyunjae Lee et al. Biomicrofluidics
- Global architecture of the F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction
- (2014) Yue Shao et al. Integrative Biology
- Microfluidic platforms for biomarker analysis
- (2014) Sofia Nahavandi et al. LAB ON A CHIP
- Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs
- (2014) Luiz E. Bertassoni et al. LAB ON A CHIP
- Clinical development success rates for investigational drugs
- (2014) Michael Hay et al. NATURE BIOTECHNOLOGY
- Ultrasoft microgels displaying emergent platelet-like behaviours
- (2014) Ashley C. Brown et al. NATURE MATERIALS
- Appreciating force and shape — the rise of mechanotransduction in cell biology
- (2014) Thomas Iskratsch et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis
- (2014) Y. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of platelet function defects by multi-parameter assessment of thrombus formation
- (2014) Susanne M. de Witt et al. Nature Communications
- Three-dimensional printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells
- (2013) B. Duan et al. Acta Biomaterialia
- Microdevice array-based identification of distinct mechanobiological response profiles in layer-specific valve interstitial cells
- (2013) Christopher Moraes et al. Integrative Biology
- Aortic Stenosis in the Elderly
- (2013) Ruben L.J. Osnabrugge et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Biomechanical regulation of vascular smooth muscle cell functions: from in vitro to in vivo understanding
- (2013) J. Qiu et al. Journal of the Royal Society Interface
- Microfluidic heart on a chip for higher throughput pharmacological studies
- (2013) Ashutosh Agarwal et al. LAB ON A CHIP
- Side view thrombosis microfluidic device with controllable wall shear rate and transthrombus pressure gradient
- (2013) Ryan W. Muthard et al. LAB ON A CHIP
- Engineering of functional, perfusable 3D microvascular networks on a chip
- (2013) Sudong Kim et al. LAB ON A CHIP
- Hemodynamic features and platelet aggregation in a stenosed microchannel
- (2013) Hojin Ha et al. MICROVASCULAR RESEARCH
- Of men, not mice
- (2013) NATURE MEDICINE
- An Investigation on Platelet Transport during Thrombus Formation at Micro-Scale Stenosis
- (2013) Francisco Javier Tovar-Lopez et al. PLoS One
- Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner
- (2013) Erik Westein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro
- (2013) D.-H. T. Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High Content Evaluation of Shear Dependent Platelet Function in a Microfluidic Flow Assay
- (2012) Ryan R. Hansen et al. ANNALS OF BIOMEDICAL ENGINEERING
- Microfluidic artificial “vessels” for dynamic mechanical stimulation of mesenchymal stem cells
- (2012) Jing Zhou et al. Integrative Biology
- Microfluidic system for simultaneous optical measurement of platelet aggregation at multiple shear rates in whole blood
- (2012) Melissa Li et al. LAB ON A CHIP
- Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)
- (2012) Ross Booth et al. LAB ON A CHIP
- A microfluidic flow-stretch chip for investigating blood vessel biomechanics
- (2012) Wenfu Zheng et al. LAB ON A CHIP
- A modular approach to create a neurovascular unit-on-a-chip
- (2012) Anil Kumar H. Achyuta et al. LAB ON A CHIP
- Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
- (2012) I. K. Zervantonakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds
- (2012) L A Hockaday et al. Biofabrication
- Endothelial Cell Culture Model for Replication of Physiological Profiles of Pressure, Flow, Stretch, and Shear Stressin Vitro
- (2011) Rosendo Estrada et al. ANALYTICAL CHEMISTRY
- Design properties of hydrogel tissue-engineering scaffolds
- (2011) Junmin Zhu et al. Expert Review of Medical Devices
- Animal Models of Cardiovascular Diseases
- (2011) Carlos Zaragoza et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip
- (2011) Anna Grosberg et al. LAB ON A CHIP
- A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response
- (2011) Jennifer M. Mann et al. LAB ON A CHIP
- Characterization of In Vitro Endothelial Linings Grown Within Microfluidic Channels
- (2011) Mandy B. Esch et al. TISSUE ENGINEERING PART A
- Technique for Real-Time Measurements of Endothelial Permeability in a Microfluidic Membrane Chip Using Laser-Induced Fluorescence Detection
- (2010) Edmond W. K. Young et al. ANALYTICAL CHEMISTRY
- Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro
- (2010) Valerie L. Cross et al. BIOMATERIALS
- Thrombin Flux and Wall Shear Rate Regulate Fibrin Fiber Deposition State during Polymerization under Flow
- (2010) K.B. Neeves et al. BIOPHYSICAL JOURNAL
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- Integrated microfluidic chip for endothelial cells culture and analysis exposed to a pulsatile and oscillatory shear stress
- (2009) Jianbo Shao et al. LAB ON A CHIP
- A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood
- (2009) Francisco Javier Tovar-Lopez et al. LAB ON A CHIP
- Development and evaluation of microdevices for studying anisotropic biaxial cyclic stretch on cells
- (2008) Wei Tan et al. BIOMEDICAL MICRODEVICES
- Microfluidic devices for studies of shear-dependent platelet adhesion
- (2008) Edgar Gutierrez et al. LAB ON A CHIP
- A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood
- (2008) Keith B. Neeves et al. LAB ON A CHIP
- Mechanotransduction in vascular physiology and atherogenesis
- (2008) Cornelia Hahn et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now