Analyzing the shear‐induced sensitization of mechanosensitive ion channel Piezo‐1 in human aortic endothelial cells

Rutaecarpine prevented ox-LDL-induced VSMCs dysfunction through inhibiting overexpression of connexin 43

(2019) Meiling Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

(2019) Emily E. Friedrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PIEZO1-Mediated Currents Are Modulated by Substrate Mechanics

(2019) Navid Bavi et al.   ACS Nano

A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel

(2018) Yanfeng Wang et al.   Nature Communications

Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1

(2018) Mohammad M. Maneshi et al.   Scientific Reports

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

(2018) Keiko Nonomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mechanosensitive Piezo1 channel: structural features and molecular bases underlying its ion permeation and mechanotransduction

(2017) Yubo Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structure of the mechanically activated ion channel Piezo1

(2017) Kei Saotome et al.   NATURE

How cells channel their stress: Interplay between Piezo1 and the cytoskeleton

(2017) Jamison L. Nourse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Lateral trapezoid microfluidic platform for investigating mechanotransduction of cells to spatial shear stress gradients

(2017) Rebecca Soffe et al.   SENSORS AND ACTUATORS B-CHEMICAL

A protein interaction mechanism for suppressing the mechanosensitive Piezo channels

(2017) Tingxin Zhang et al.   Nature Communications

Endothelial fluid shear stress sensing in vascular health and disease

(2016) Nicolas Baeyens et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells

(2015) Sara Baratchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Examination of the role of transient receptor potential vanilloid type 4 in endothelial responses to shear forces

(2014) Sara Baratchi et al.   Biomicrofluidics

Microfluidic platforms for biomarker analysis

(2014) Sofia Nahavandi et al.   LAB ON A CHIP

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear stress triggers insertion of voltage-gated potassium channels from intracellular compartments in atrial myocytes

(2013) H. E. Boycott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple roles for the actin cytoskeleton during regulated exocytosis

(2012) Natalie Porat-Shliom et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gating the mechanical channel Piezo1

(2012) Philip A. Gottlieb et al.   Channels

Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity

(2010) Patrizia Nigro et al.   ANTIOXIDANTS & REDOX SIGNALING

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY