Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model
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Title
Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model
Authors
Keywords
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Journal
Small
Volume 13, Issue 15, Pages 1603737
Publisher
Wiley
Online
2017-02-17
DOI
10.1002/smll.201603737
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Note: Only part of the references are listed.- A Shearing-Stretching Device That Can Apply Physiological Fluid Shear Stress and Cyclic Stretch Concurrently to Endothelial Cells
- (2016) Daphne Meza et al. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
- Elastomeric free-form blood vessels for interconnecting organs on chip systems
- (2016) Weijia Zhang et al. LAB ON A CHIP
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- (2016) Wenfu Zheng et al. Small
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- (2016) S Blondel et al. Cell Death & Disease
- Progeria, rapamycin and normal aging: recent breakthrough
- (2016) Mikhail V. Blagosklonny Aging-US
- Accelerated aging syndromes, are they relevant to normal human aging?
- (2016) Oliver Dreesen et al. Aging-US
- Hutchinson–Gilford progeria syndrome as a model for vascular aging
- (2015) Jonathan A. Brassard et al. BIOGERONTOLOGY
- On-chip assessment of human primary cardiac fibroblasts proliferative responses to uniaxial cyclic mechanical strain
- (2015) Giovanni Stefano Ugolini et al. BIOTECHNOLOGY AND BIOENGINEERING
- Vascular biology of ageing—Implications in hypertension
- (2015) Adam Harvey et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A medium throughput device to study the effects of combinations of surface strains and fluid-flow shear stresses on cells
- (2015) R. Sinha et al. LAB ON A CHIP
- Restoring SIRT6 Expression in Hutchinson-Gilford Progeria Syndrome Cells Impedes Premature Senescence and Formation of Dysmorphic Nuclei
- (2015) Helal Endisha et al. PATHOBIOLOGY
- Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip
- (2015) Hyun Jung Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- Investigating human disease using stem cell models
- (2014) Jared L. Sterneckert et al. NATURE REVIEWS GENETICS
- Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
- (2014) Pierre Cau et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
- (2014) Diana Jurk et al. Nature Communications
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
- (2013) Mariaceleste Aragona et al. CELL
- N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A
- (2013) Maurizio Bifulco et al. FEBS Journal
- Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation
- (2013) Hyun Jung Kim et al. Integrative Biology
- Microfluidic platforms for mechanobiology
- (2013) William J. Polacheck et al. LAB ON A CHIP
- A novel system for studying mechanical strain waveform-dependent responses in vascular smooth muscle cells
- (2013) Jason Lee et al. LAB ON A CHIP
- Cyclic Tensile Strain Controls Cell Shape and Directs Actin Stress Fiber Formation and Focal Adhesion Alignment in Spreading Cells
- (2013) Alexandra M. Greiner et al. PLoS One
- Uniaxial cell stretching device for live-cell imaging of mechanosensitive cellular functions
- (2013) Yue Shao et al. REVIEW OF SCIENTIFIC INSTRUMENTS
- Precise determination of the Poisson ratio in soft materials with 2D digital image correlation
- (2013) Robyn H. Pritchard et al. Soft Matter
- The Intersection Between Aging and Cardiovascular Disease
- (2012) Brian J. North et al. CIRCULATION RESEARCH
- Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension
- (2012) Eric D. Austin et al. Circulation-Cardiovascular Genetics
- Nuclear lamina defects cause ATM-dependent NF- B activation and link accelerated aging to a systemic inflammatory response
- (2012) F. G. Osorio et al. GENES & DEVELOPMENT
- Microfluidic artificial “vessels” for dynamic mechanical stimulation of mesenchymal stem cells
- (2012) Jing Zhou et al. Integrative Biology
- The Effect of Pressure-Induced Mechanical Stretch on Vascular Wall Differential Gene Expression
- (2012) M.A. Anwar et al. JOURNAL OF VASCULAR RESEARCH
- Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
- (2012) Hyun Jung Kim et al. LAB ON A CHIP
- Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome
- (2012) L. B. Gordon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice
- (2012) Dongeun Huh et al. Science Translational Medicine
- Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA
- (2012) Xavier Nissan et al. Cell Reports
- Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
- (2011) Kan Cao et al. JOURNAL OF CLINICAL INVESTIGATION
- Role of shear stress and stretch in vascular mechanobiology
- (2011) D. Lu et al. Journal of the Royal Society Interface
- Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
- (2011) Guang-Hui Liu et al. NATURE
- The Farnesyltransferase Inhibitors Tipifarnib and Lonafarnib Inhibit Cytokines Secretion in a Cellular Model of Mevalonate Kinase Deficiency
- (2011) Annalisa Marcuzzi et al. PEDIATRIC RESEARCH
- Towards the Maturation and Characterization of Smooth Muscle Cells Derived from Human Embryonic Stem Cells
- (2011) Helena Vazão et al. PLoS One
- Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging
- (2010) Michelle Olive et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
- (2010) Jinqiu Zhang et al. Cell Stem Cell
- Reactive Oxygen Species, NADPH Oxidases, and Hypertension
- (2010) Srinivasa Raju Datla et al. HYPERTENSION
- Inflammation, Immunity, and Hypertension
- (2010) David G. Harrison et al. HYPERTENSION
- Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model
- (2010) Nicholas J. Douville et al. LAB ON A CHIP
- Progeria syndromes and ageing: what is the connection?
- (2010) Christopher R. Burtner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- Increased mechanosensitivity and nuclear stiffness in Hutchinson–Gilford progeria cells: effects of farnesyltransferase inhibitors
- (2008) Valerie L. R. M. Verstraeten et al. AGING CELL
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
- (2008) Juan C. Acosta et al. CELL
- Nuclear Shape, Mechanics, and Mechanotransduction
- (2008) Kris Noel Dahl et al. CIRCULATION RESEARCH
- NADPH Oxidases, Reactive Oxygen Species, and Hypertension: Clinical implications and therapeutic possibilities
- (2008) T. M. Paravicini et al. DIABETES CARE
- Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
- (2008) Ignacio Varela et al. NATURE MEDICINE
- Phenotype and Course of Hutchinson–Gilford Progeria Syndrome
- (2008) Melissa A. Merideth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Role of Cyclic Strain Frequency in Regulating the Alignment of Vascular Smooth Muscle Cells In Vitro
- (2007) Bo Liu et al. BIOPHYSICAL JOURNAL
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