The effects of particle size, shape, density and flow characteristics on particle margination to vascular walls in cardiovascular diseases

Facile production of nanoaggregates with tuneable morphologies from thermoresponsive P(DEGMA-co-HPMA)

(2016) Nghia P. Truong et al.   Polymer Chemistry

Polymeric filomicelles and nanoworms: two decades of synthesis and application

(2016) Nghia P. Truong et al.   Polymer Chemistry

Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis

(2016) Xiaowei Wang et al.   Theranostics

Size Dependent Cellular Uptake of Rod-like Bionanoparticles with Different Aspect Ratios

(2016) Xiangxiang Liu et al.   Scientific Reports

Dense nanoparticles exhibit enhanced vascular wall targeting over neutrally buoyant nanoparticles in human blood flow

(2015) Alex J. Thompson et al.   Acta Biomaterialia

Treatment of Invasive Brain Tumors Using a Chain-like Nanoparticle

(2015) P. M. Peiris et al.   CANCER RESEARCH

Executive Summary: Heart Disease and Stroke Statistics—2015 Update:

(2015) Dariush Mozaffarian et al.   CIRCULATION

Vascular Targeting of a Gold Nanoparticle to Breast Cancer Metastasis

(2015) Pubudu M. Peiris et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nanomedicines for endothelial disorders

(2015) Bomy Lee Chung et al.   Nano Today

Shaping bio-inspired nanotechnologies to target thrombosis for dual optical-magnetic resonance imaging

(2015) Amy M. Wen et al.   Journal of Materials Chemistry B

Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration

(2014) Elizabeth Nance et al.   ACS Nano

Cardiovascular drug delivery with ultrasound and microbubbles

(2014) Evan Unger et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeted Antithrombotic Protein Micelles

(2014) Wookhyun Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo evaluation of vascular-targeted spheroidal microparticles for imaging and drug delivery application in atherosclerosis

(2014) Katawut Namdee et al.   ATHEROSCLEROSIS

The importance of nanoparticle shape in cancer drug delivery

(2014) Nghia P Truong et al.   Expert Opinion on Drug Delivery

The margination propensity of ellipsoidal micro/nanoparticles to the endothelium in human blood flow

(2013) Alex J. Thompson et al.   BIOMATERIALS

Treatment of cancer micrometastasis using a multicomponent chain-like nanoparticle

(2013) Pubudu M. Peiris et al.   JOURNAL OF CONTROLLED RELEASE

Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels

(2013) Katawut Namdee et al.   LANGMUIR

On-Command Drug Release from Nanochains Inhibits Growth of Breast Tumors

(2013) Pubudu M. Peiris et al.   PHARMACEUTICAL RESEARCH

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the near-wall accumulation of injectable particles in the microcirculation: smaller is not better

(2013) Tae-Rin Lee et al.   Scientific Reports

Enhanced Delivery of Chemotherapy to Tumors Using a Multicomponent Nanochain with Radio-Frequency-Tunable Drug Release

(2012) Pubudu M. Peiris et al.   ACS Nano

Imaging Metastasis Using an Integrin-Targeting Chain-Shaped Nanoparticle

(2012) Pubudu M. Peiris et al.   ACS Nano

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

The preferential targeting of the diseased microvasculature by disk-like particles

(2012) Giulia Adriani et al.   BIOMATERIALS

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis

(2012) Xiaowei Wang et al.   CIRCULATION

Prediction of Progression of Coronary Artery Disease and Clinical Outcomes Using Vascular Profiling of Endothelial Shear Stress and Arterial Plaque Characteristics

(2012) Peter H. Stone et al.   CIRCULATION

Particle-cell dynamics in human blood flow: Implications for vascular-targeted drug delivery

(2012) Phapanin Charoenphol et al.   JOURNAL OF BIOMECHANICS

Nanomedicine for the prevention, treatment and imaging of atherosclerosis

(2012) Costas Psarros et al.   Nanomedicine-Nanotechnology Biology and Medicine

Endothelial Targeting of Antibody-Decorated Polymeric Filomicelles

(2011) Vladimir V. Shuvaev et al.   ACS Nano

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

Targeting therapeutics to the vascular wall in atherosclerosis–Carrier size matters

(2011) Phapanin Charoenphol et al.   ATHEROSCLEROSIS

Concurrent blood–brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment

(2011) Chien-Yu Ting et al.   BIOMATERIALS

Enzymatic Single-Chain Antibody Tagging

(2011) H.T. Ta et al.   CIRCULATION RESEARCH

Inorganic nanoparticles for cancer imaging and therapy

(2011) Huang-Chiao Huang et al.   JOURNAL OF CONTROLLED RELEASE

The effects of particle size, density and shape on margination of nanoparticles in microcirculation

(2011) Randall Toy et al.   NANOTECHNOLOGY

Perspectives and opportunities for nanomedicine in the management of atherosclerosis

(2011) Mark E. Lobatto et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Assembly of Linear Nano-Chains from Iron Oxide Nanospheres with Asymmetric Surface Chemistry

(2011) Pubudu M. Peiris et al.   PLoS One

Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages

(2010) Arnida et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Flow and adhesion of drug carriers in blood vessels depend on their shape: A study using model synthetic microvascular networks

(2010) Nishit Doshi et al.   JOURNAL OF CONTROLLED RELEASE

Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review)

(2010) Ryan B. Huang et al.   MOLECULAR MEMBRANE BIOLOGY

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function

(2009) Xinglu Huang et al.   BIOMATERIALS

Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers

(2009) Phapanin Charoenphol et al.   BIOMATERIALS

Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows

(2009) Sei-Young Lee et al.   NANOTECHNOLOGY

Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery

(2008) Monty Liong et al.   ACS Nano

Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging

(2008) Ji-Ho Park et al.   ADVANCED MATERIALS

Hydrodynamic Shear Rate Regulates Melanoma-Leukocyte Aggregation, Melanoma Adhesion to the Endothelium, and Subsequent Extravasation

(2008) Shile Liang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Targeted delivery of therapeutics to endothelium

(2008) Eric Simone et al.   CELL AND TISSUE RESEARCH

The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows

(2008) F. Gentile et al.   JOURNAL OF BIOMECHANICS

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

Shape Induced Inhibition of Phagocytosis of Polymer Particles

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH

Intravascular Delivery of Particulate Systems: Does Geometry Really Matter?

(2008) Paolo Decuzzi et al.   PHARMACEUTICAL RESEARCH

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design maps for nanoparticles targeting the diseased microvasculature

(2007) Paolo Decuzzi et al.   BIOMATERIALS