Biomaterial-based antimicrobial therapies for the treatment of bacterial infections

The arms race between bacteria and their phage foes

(2020) Hannah G. Hampton et al.   NATURE

Antimicrobial host defence peptides: functions and clinical potential

(2020) Neeloffer Mookherjee et al.   NATURE REVIEWS DRUG DISCOVERY

A dual-action peptide-containing hydrogel targets wound infection and inflammation

(2020) Manoj Puthia et al.   Science Translational Medicine

Engineered Living Materials Based on Adhesin-Mediated Trapping of Programmable Cells

(2020) Shuaiqi Guo et al.   ACS Synthetic Biology

Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis

(2020) Antoine Roquilly et al.   NATURE IMMUNOLOGY

Antimicrobial peptides: Application informed by evolution

(2020) Brian P. Lazzaro et al.   SCIENCE

Strategies in Translating the Therapeutic Potentials of Host Defense Peptides

(2020) Darren Shu Jeng Ting et al.   Frontiers in Immunology

Enhanced therapeutic index of an antimicrobial peptide in mice by increasing safety and activity against multidrug-resistant bacteria

(2020) Y. P. Di et al.   Science Advances

A Rapid Lysostaphin Production Approach and a Convenient Novel Lysostaphin Loaded Nano-emulgel; As a Sustainable Low-Cost Methicillin-Resistant Staphylococcus aureus Combating Platform

(2020) Hanzada T. Nour El-Din et al.   Biomolecules

Exebacase for patients with Staphylococcus aureus bloodstream infection and endocarditis

(2020) Vance G. Fowler et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural cells are key regulators of organ-specific immune responses

(2020) Thomas Krausgruber et al.   NATURE

Encapsulation of the Antistaphylococcal Endolysin LysRODI in pH-Sensitive Liposomes

(2020) Silvia Portilla et al.   Antibiotics-Basel

Intravesical bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomised, placebo-controlled, double-blind clinical trial

(2020) Lorenz Leitner et al.   LANCET INFECTIOUS DISEASES

Treatment of MRSA-infected osteomyelitis using bacterial capturing, magnetically targeted composites with microwave-assisted bacterial killing

(2020) Yuqian Qiao et al.   Nature Communications

Multifunctional sulfonated polyetheretherketone coating with beta-defensin-14 for yielding durable and broad-spectrum antibacterial activity and osseointegration

(2019) Xiangwei Yuan et al.   Acta Biomaterialia

MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection

(2019) Mohammad Arifuzzaman et al.   Science Advances

Antibiotic-Free Cationic Dendritic Hydrogels as Surgical-Site-Infection-Inhibiting Coatings

(2019) Oliver C. J. Andrén et al.   Advanced Healthcare Materials

Fibrin glue as a local drug-delivery system for bacteriophage PA5

(2019) Evgenii Rubalskii et al.   Scientific Reports

The Preclinical and Clinical Progress of Bacteriophages and Their Lytic Enzymes: The Parts are Easier than the Whole

(2019) Karim Abdelkader et al.   Viruses-Basel

Biomimetic hydroxyapatite nanocrystals are an active carrier for Salmonella bacteriophages

(2019) Andrea Fulgione et al.   International Journal of Nanomedicine

Practical Preparation of Infection-Resistant Biomedical Surfaces from Antimicrobial β-Peptide Polymers

(2019) Fan Qi et al.   ACS Applied Materials & Interfaces

Design and synthesis of biocompatible, hemocompatible and highly selective antimicrobial cationic peptidopolysaccharides via click chemistry

(2019) Yun Chen et al.   BIOMACROMOLECULES

Antibacterial and osteogenesis performances of LL37-loaded titania nanopores in vitro and in vivo

(2019) Xinkun Shen et al.   International Journal of Nanomedicine

Fabrication of KR-12 peptide-containing hyaluronic acid immobilized fibrous eggshell membrane effectively kills multi-drug-resistant bacteria, promotes angiogenesis and accelerates re-epithelialization

(2019) Menglong Liu et al.   International Journal of Nanomedicine

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Lysostaphin and BMP-2 co-delivery reduces S. aureus infection and regenerates critical-sized segmental bone defects

(2019) Christopher T. Johnson et al.   Science Advances

O‐Mannosylation Affords a Glycopeptide Hydrogel with Inherent Antibacterial Activities against E. coli via Multivalent Interactions between Lectins and Supramolecular Assemblies

(2019) Jing Li et al.   MACROMOLECULAR BIOSCIENCE

Hydrogels Embedded With Melittin and Tobramycin Are Effective Against Pseudomonas aeruginosa Biofilms in an Animal Wound Model

(2019) Michael M. Maiden et al.   Frontiers in Microbiology

Catalytic antimicrobial robots for biofilm eradication

(2019) Geelsu Hwang et al.   Science Robotics

pH-Switchable Antimicrobial Nanofiber Networks of Hydrogel Eradicate Biofilm and Rescue Stalled Healing in Chronic Wounds

(2019) Jianhao Wang et al.   ACS Nano

Prophylaxis of Mycobacterium tuberculosis H37Rv Infection in a Preclinical Mouse Model via Inhalation of Nebulized Bacteriophage D29

(2019) Nicholas B. Carrigy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacteriophage delivering hydrogels reduce biofilm formation in vitro and infection in vivo

(2019) James A. Wroe et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5

(2019) Sylvia N. Kłodzińska et al.   Nanomedicine-Nanotechnology Biology and Medicine

Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia

(2019) Elizabeth M. Todd et al.   Science Advances

Microencapsulation of Enteric Bacteriophages in a pH-Responsive Solid Oral Dosage Formulation Using a Scalable Membrane Emulsification Process

(2019) Vinner et al.   Pharmaceutics

Antimicrobial Peptide-Conjugated Hierarchical Antifouling Polymer Brushes for Functionalized Catheter Surfaces

(2019) Xin-Yang Zhang et al.   BIOMACROMOLECULES

Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017

(2019) Lindsey M. Weiner-Lastinger et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Antimicrobial-resistant pathogens associated with pediatric healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017

(2019) Lindsey M. Weiner-Lastinger et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Comprehensive evaluation of chitosan nanoparticle based phage lysin delivery system; a novel approach to counter S. pneumoniae infections

(2019) Vijay Singh Gondil et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Facile and efficient encapsulation of antimicrobial peptides via crosslinked DNA nanostructures and their application in wound therapy

(2019) Sybil Obuobi et al.   JOURNAL OF CONTROLLED RELEASE

Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b

(2019) Luz S. Gonzalez-Delgado et al.   Nature Chemical Biology

Celebrating 100 years of polymer science

(2019) Guy C. Berry et al.   PROGRESS IN POLYMER SCIENCE

Antibiotic‐Free Antibacterial Strategies Enabled by Nanomaterials: Progress and Perspectives

(2019) Yue Wang et al.   ADVANCED MATERIALS

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(2019) Ann Marie Prazak et al.   CRITICAL CARE MEDICINE

Encapsulated bacteriophages in alginate-nanohydroxyapatite hydrogel as a novel delivery system to prevent orthopedic implant-associated infections

(2019) Joana Alberta Ribeiro Barros et al.   Nanomedicine-Nanotechnology Biology and Medicine

New drugs for the antibacterial pipeline?

(2019) Ashley York   NATURE REVIEWS MICROBIOLOGY

The synergistic effects of SrF2 nanoparticles, YSZ nanoparticles, and poly-ε-l-lysin on physicomechanical, ion release, and antibacterial-cellular behavior of the flowable dental composites

(2019) Saeed Hesaraki et al.   Materials Science & Engineering C-Materials for Biological Applications

Antibacterial and Biocompatible Cross-Linked Waterborne Polyurethanes Containing Gemini Quaternary Ammonium Salts

(2018) Yi Zhang et al.   BIOMACROMOLECULES

Anti-infective biomaterials with surface-decorated tachyplesin I

(2018) Qiong Xue et al.   BIOMATERIALS

Anhydrous polymer-based coating with sustainable controlled release functionality for facile, efficacious impregnation, and delivery of antimicrobial peptides

(2018) Kaiyang Lim et al.   BIOTECHNOLOGY AND BIOENGINEERING

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy

(2018) Rokeya Sultana Rekha et al.   BMC INFECTIOUS DISEASES

Immunomimetic Designer Cells Protect Mice from MRSA Infection

(2018) Ying Liu et al.   CELL

The Standardized Antimicrobial Administration Ratio: A New Metric for Measuring and Comparing Antibiotic Use

(2018) Katharina L van Santen et al.   CLINICAL INFECTIOUS DISEASES

Preparation, characterization and efficacy of lysostaphin-chitosan gel against Staphylococcus aureus

(2018) Sai Nithya et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Incorporation of bacteriophages in polycaprolactone/collagen fibers for antibacterial hemostatic dual-function

(2018) Weilu Cheng et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Block Copolymer Nanoparticles Remove Biofilms of Drug-Resistant Gram-Positive Bacteria by Nanoscale Bacterial Debridement

(2018) Jianghua Li et al.   NANO LETTERS

Comparison of the immune response during acute and chronic Staphylococcus aureus infection

(2018) Rebecca A. Brady et al.   PLoS One

Hydrogel delivery of lysostaphin eliminates orthopedic implant infection byStaphylococcus aureusand supports fracture healing

(2018) Christopher T. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

(2018) Willy Chin et al.   Nature Communications

Liposome Entrapment of Bacteriophages Improves Wound Healing in a Diabetic Mouse MRSA Infection

(2018) Sanjay Chhibber et al.   Frontiers in Microbiology

Daylight-driven rechargeable antibacterial and antiviral nanofibrous membranes for bioprotective applications

(2018) Yang Si et al.   Science Advances

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections

(2018) Rachit Agarwal et al.   Nature Biomedical Engineering

Comparison of the antibacterial effects of a short cationic peptide and 1% silver bioactive glass against extensively drug-resistant bacteria, Pseudomonas aeruginosa and Acinetobacter baumannii, isolated from burn patients

(2018) Mehrdad Moosazadeh Moghaddam et al.   AMINO ACIDS

Sustained Release of Antimicrobial Peptide from Self-Assembling Hydrogel Enhanced Osteogenesis

(2018) Guoli Yang et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Conversion of staphylococcal pathogenicity islands to CRISPR-carrying antibacterial agents that cure infections in mice

(2018) Geeta Ram et al.   NATURE BIOTECHNOLOGY

Recent achievements and perspectives for large-scale recombinant production of antimicrobial peptides

(2018) David Wibowo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Biofilm-associated infection by enterococci

(2018) Jun-Hong Ch’ng et al.   NATURE REVIEWS MICROBIOLOGY

Development of Silicone Hydrogel Antimicrobial Contact Lenses with Mel4 Peptide Coating

(2018) Debarun Dutta et al.   OPTOMETRY AND VISION SCIENCE

High Throughput Manufacturing of Bacteriophages Using Continuous Stirred Tank Bioreactors Connected in Series to Ensure Optimum Host Bacteria Physiology for Phage Production

(2018) Francesco Mancuso et al.   Viruses-Basel

Macromolecular-clustered facial amphiphilic antimicrobials

(2018) Md Anisur Rahman et al.   Nature Communications

Contribution of Dendritic Cell Responses to Sepsis-Induced Immunosuppression and to Susceptibility to Secondary Pneumonia

(2018) Marwan Bouras et al.   Frontiers in Immunology

Ex vivo and in vivo evaluation of microemulsion based transdermal delivery of E . coli specific T4 bacteriophage: A rationale approach to treat bacterial infection

(2017) Vaibhav Rastogi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Apitherapeutics and phage-loaded nanofibers as wound dressings with enhanced wound healing and antibacterial activity

(2017) Wessam A Sarhan et al.   Nanomedicine

Targeting microbial biofilms: current and prospective therapeutic strategies

(2017) Hyun Koo et al.   NATURE REVIEWS MICROBIOLOGY

Antibiotic tolerance facilitates the evolution of resistance

(2017) Irit Levin-Reisman et al.   SCIENCE

Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice

(2017) Nadine Lohmann et al.   Science Translational Medicine

New class of precision antimicrobials redefines role of Clostridium difficile S-layer in virulence and viability

(2017) Joseph A. Kirk et al.   Science Translational Medicine

Bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomized, placebo-controlled, double-blind clinical trial

(2017) Lorenz Leitner et al.   BMC Urology

Prevention of encrustation and blockage of urinary catheters by Proteus mirabilis via pH-triggered release of bacteriophage

(2017) Scarlet Milo et al.   Journal of Materials Chemistry B

THPdb: Database of FDA-approved peptide and protein therapeutics

(2017) Salman Sadullah Usmani et al.   PLoS One

Microencapsulation of Clostridium difficile specific bacteriophages using microfluidic glass capillary devices for colon delivery using pH triggered release

(2017) Gurinder K. Vinner et al.   PLoS One

Microencapsulation with alginate/CaCO3: A strategy for improved phage therapy

(2017) Joan Colom et al.   Scientific Reports

A Biodegradable Polycationic Paint that Kills Bacteria in Vitro and in Vivo

(2016) Jiaul Hoque et al.   ACS Applied Materials & Interfaces

Antimicrobial peptide melimine coating for titanium and its in vivo antibacterial activity in rodent subcutaneous infection models

(2016) Renxun Chen et al.   BIOMATERIALS

One-step synthesis of high-density peptide-conjugated gold nanoparticles with antimicrobial efficacy in a systemic infection model

(2016) Akhilesh Rai et al.   BIOMATERIALS

Industrialization of lipid nanoparticles: From laboratory-scale to large-scale production line

(2016) Caibiao Hu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014

(2016) Lindsey M. Weiner et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation

(2016) Peng Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Alternatives to antibiotics—a pipeline portfolio review

(2016) Lloyd Czaplewski et al.   LANCET INFECTIOUS DISEASES

A Hydrogel-Based Localized Release of Colistin for Antimicrobial Treatment of Burn Wound Infection

(2016) Chongyu Zhu et al.   MACROMOLECULAR BIOSCIENCE

Chitosan Nanoparticles as Carriers for the Delivery of ΦKAZ14 Bacteriophage for Oral Biological Control of Colibacillosis in Chickens

(2016) Adamu Ahmad Kaikabo et al.   MOLECULES

New mechanisms, new worries

(2016) M. Sprenger et al.   SCIENCE

Antimicrobial activity of a quaternary ammonium methacryloxy silicate-containing acrylic resin: a randomised clinical trial

(2016) Si-ying Liu et al.   Scientific Reports

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

(2016) Amy Langdon et al.   Genome Medicine

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

(2016) Shu J. Lam et al.   Nature Microbiology

A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity

(2016) Yizhi Qi et al.   Nature Biomedical Engineering

In Vivo Assessment of Phage and Linezolid Based Implant Coatings for Treatment of Methicillin Resistant S. aureus (MRSA) Mediated Orthopaedic Device Related Infections

(2016) Sandeep Kaur et al.   PLoS One

Anti-biofilm properties of wound dressing incorporating nonrelease polycationic antimicrobials

(2015) Livnat Atar-Froyman et al.   BIOMATERIALS

Versatile antimicrobial peptide-based ZnO quantum dots for in vivo bacteria diagnosis and treatment with high specificity

(2015) Haiyan Chen et al.   BIOMATERIALS

Depletion of T Cell Epitopes in Lysostaphin Mitigates Anti-Drug Antibody Response and Enhances Antibacterial Efficacy In Vivo

(2015) Hongliang Zhao et al.   CHEMISTRY & BIOLOGY

Design of antimicrobial peptides conjugated biodegradable citric acid derived hydrogels for wound healing

(2015) Zhiwei Xie et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Bacteriophage-Loaded Nanostructured Lipid Carrier: Improved Pharmacokinetics Mediates Effective Resolution ofKlebsiella pneumoniae–Induced Lobar Pneumonia

(2015) Saloni Singla et al.   JOURNAL OF INFECTIOUS DISEASES

Antibacterial, anti-inflammatory and neuroprotective layer-by-layer coatings for neural implants

(2015) Zhiling Zhang et al.   Journal of Neural Engineering

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological and immunotoxicity evaluation of antimicrobial peptide-loaded coatings using a layer-by-layer process on titanium

(2015) Jue Shi et al.   Scientific Reports

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance

(2015) Kristina Blazanovic et al.   Molecular Therapy-Methods & Clinical Development

Self-Defensive Layer-by-Layer Films with Bacteria-Triggered Antibiotic Release

(2014) Iryna Zhuk et al.   ACS Nano

Gram-Positive Antimicrobial Activity of Amino Acid-Based Hydrogels

(2014) I. Irwansyah et al.   ADVANCED MATERIALS

Bacteriophage-Mediated Control of a Two-Species Biofilm Formed by Microorganisms Causing Catheter-Associated Urinary Tract Infections in anIn VitroUrinary Catheter Model

(2014) Susan M. Lehman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cationic Antimicrobial Peptides Cytotoxicity on Mammalian Cells: An Analysis Using Therapeutic Index Integrative Concept

(2014) M. Bacalum et al.   International Journal of Peptide Research and Therapeutics

Sustained and controlled release of lipophilic drugs from a self-assembling amphiphilic peptide hydrogel

(2014) Maria-Lucia Briuglia et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Bacteriophage K Antimicrobial-Lock Technique for Treatment of Staphylococcus aureus Central Venous Catheter–Related Infection: A Leporine Model Efficacy Analysis

(2014) Matthew P. Lungren et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Molecular mechanisms of antibiotic resistance

(2014) Jessica M. A. Blair et al.   NATURE REVIEWS MICROBIOLOGY

Biocompatibility of Antimicrobial Melimine Lenses

(2014) Debarun Dutta et al.   OPTOMETRY AND VISION SCIENCE

Lysostaphin-Coated Titan-Implants Preventing Localized Osteitis by Staphylococcus aureus in a Mouse Model

(2014) Ceylan D. Windolf et al.   PLoS One

A Novel Controlled-Release System for Antibacterial Enzyme Lysostaphin Delivery Using Hydroxyapatite/Chitosan Composite Bone Cement

(2014) Bai Xue et al.   PLoS One

A multifunctional bispecific antibody protects against Pseudomonas aeruginosa

(2014) A. DiGiandomenico et al.   Science Translational Medicine

Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs

(2014) Joanne L. Fothergill et al.   Nature Communications

Broad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response

(2014) César de la Fuente-Núñez et al.   PLoS Pathogens

Biofilms and chronic wound inflammation

(2014) R.D. Wolcott et al.   Journal of Wound Care

Molecular Structure of RADA16-I Designer Self-Assembling Peptide Nanofibers

(2013) Ashley R. Cormier et al.   ACS Nano

Antimicrobial Polycarbonates: Investigating the Impact of Balancing Charge and Hydrophobicity Using a Same-Centered Polymer Approach

(2013) Amanda C. Engler et al.   BIOMACROMOLECULES

Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections

(2013) Mehdi Kazemzadeh-Narbat et al.   BIOMATERIALS

Spread of extensively resistant VIM-2-positive ST235 Pseudomonas aeruginosa in Belarus, Kazakhstan, and Russia: a longitudinal epidemiological and clinical study

(2013) Mikhail V Edelstein et al.   LANCET INFECTIOUS DISEASES

Effect of pneumococcal Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10) on outpatient antimicrobial purchases: a double-blind, cluster randomised phase 3–4 trial

(2013) Arto A Palmu et al.   LANCET INFECTIOUS DISEASES

Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins

(2013) Mark G.P. Saifer et al.   MOLECULAR IMMUNOLOGY

The Anti-Pseudomonas aeruginosa Antibody Panobacumab Is Efficacious on Acute Pneumonia in Neutropenic Mice and Has Additive Effects with Meropenem

(2013) Thomas Secher et al.   PLoS One

EFFICIENT PRODUCTION OFStaphylococcus simulansLYSOSTAPHIN IN A BENCHTOP BIOREACTOR BY RECOMBINANTEscherichia coli

(2013) Piotr Szweda et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial

(2012) Rubhana Raqib et al.   BMC INFECTIOUS DISEASES

Antistaphylococcal activity of bacteriophage derived chimeric protein P128

(2012) Aradhana A Vipra et al.   BMC MICROBIOLOGY

Eudragit®: a technology evaluation

(2012) Seema Thakral et al.   Expert Opinion on Drug Delivery

Bacteriophages are synergistic with bacterial interference for the prevention ofPseudomonas aeruginosabiofilm formation on urinary catheters

(2012) K.S. Liao et al.   JOURNAL OF APPLIED MICROBIOLOGY

Drug release and bone growth studies of antimicrobial peptide-loaded calcium phosphate coating on titanium

(2012) Mehdi Kazemzadeh-Narbat et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

New antibacterial microporous CaP materials loaded with phages for prophylactic treatment in bone surgery

(2012) Edwige Meurice et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Modulating immunity as a therapy for bacterial infections

(2012) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

Biodegradable nanostructures with selective lysis of microbial membranes

(2011) Fredrik Nederberg et al.   Nature Chemistry

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

(2011) A. Nuccitelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation and characterization of niosomal gel for iontophoresis mediated transdermal delivery of isosorbide dinitrate

(2011) Sanyog Jain et al.   Drug Delivery and Translational Research

Antistaphylococcal Nanocomposite Films Based on Enzyme−Nanotube Conjugates

(2010) Ravindra C. Pangule et al.   ACS Nano

Development of chitosan-collagen hydrogel incorporated with lysostaphin (CCHL) burn dressing with anti-methicillin-resistant Staphylococcus aureus and promotion wound healing properties

(2010) Fuying Cui et al.   DRUG DELIVERY

Enhanced alginate microspheres as means of oral delivery of bacteriophage for reducing Staphylococcus aureus intestinal carriage

(2010) Yongsheng Ma et al.   FOOD HYDROCOLLOIDS

In vitro lung delivery of bacteriophages KS4-M and ΦKZ using dry powder inhalers for treatment of Burkholderia cepacia complex and Pseudomonas aeruginosa infections in cystic fibrosis

(2010) L. Golshahi et al.   JOURNAL OF APPLIED MICROBIOLOGY

Bacteriophage resistance mechanisms

(2010) Simon J. Labrie et al.   NATURE REVIEWS MICROBIOLOGY

Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System

(2009) W. Fu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Facile synthesis of responsive nanoparticles with reversible, tunable and rapid thermal transitions from biocompatible constituents

(2009) Samer R. Abulateefeh et al.   CHEMICAL COMMUNICATIONS

Amphiphilic TiO2Nanotube Arrays: An Actively Controllable Drug Delivery System

(2009) Yan-Yan Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent

(2009) Lihong Liu et al.   Nature Nanotechnology

Preventing biofilms of clinically relevant organisms using bacteriophage

(2009) Rodney M. Donlan   TRENDS IN MICROBIOLOGY

Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform

(2008) Liangfang Zhang et al.   ACS Nano

Antimicrobial Polymers Prepared by ROMP with Unprecedented Selectivity: A Molecular Construction Kit Approach

(2008) Karen Lienkamp et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY