A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

Antimicrobial peptides and wound healing: biological and therapeutic considerations

(2016) Maria Luisa Mangoni et al.   EXPERIMENTAL DERMATOLOGY

Single-point mutation–mediated local amphipathic adjustment dramatically enhances antibacterial activity of a fungal defensin

(2016) Jiajia Wu et al.   FASEB JOURNAL

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes

(2016) Kantaraja Chindera et al.   Scientific Reports

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

(2016) Margit Mahlapuu et al.   Frontiers in Cellular and Infection Microbiology

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

(2016) Shu J. Lam et al.   Nature Microbiology

Defensive remodeling: How bacterial surface properties and biofilm formation promote resistance to antimicrobial peptides

(2015) Reut Nuri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Biodegradable Antimicrobial Polycarbonates with In Vivo Efficacy against Multidrug-Resistant MRSA Systemic Infection

(2015) Junchi Cheng et al.   Advanced Healthcare Materials

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Cationic Methacrylate Polymers as Topical Antimicrobial Agents against Staphylococcus aureus Nasal Colonization

(2014) Laura M. Thoma et al.   BIOMACROMOLECULES

Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

(2014) Abiola O. Olaitan et al.   Frontiers in Microbiology

Short Syntheticβ-Sheet Forming Peptide Amphiphiles as Broad Spectrum Antimicrobials with Antibiofilm and Endotoxin Neutralizing Capabilities

(2013) Zhan Yuin Ong et al.   ADVANCED FUNCTIONAL MATERIALS

Antimicrobial Polycarbonates: Investigating the Impact of Balancing Charge and Hydrophobicity Using a Same-Centered Polymer Approach

(2013) Amanda C. Engler et al.   BIOMACROMOLECULES

Guanylated Polymethacrylates: A Class of Potent Antimicrobial Polymers with Low Hemolytic Activity

(2013) Katherine E. S. Locock et al.   BIOMACROMOLECULES

Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic β-sheet forming peptide amphiphiles

(2013) Zhan Yuin Ong et al.   BIOMATERIALS

Biodegradable Broad-Spectrum Antimicrobial Polycarbonates: Investigating the Role of Chemical Structure on Activity and Selectivity

(2013) Willy Chin et al.   MACROMOLECULES

Enhancement of Cationic Antimicrobial Materials via Cholesterol Incorporation

(2013) Daniel J. Coady et al.   Advanced Healthcare Materials

Cationic Spacer Arm Design Strategy for Control of Antimicrobial Activity and Conformation of Amphiphilic Methacrylate Random Copolymers

(2012) Edmund F. Palermo et al.   BIOMACROMOLECULES

Design of hybrid β-hairpin peptides with enhanced cell specificity and potent anti-inflammatory activity

(2012) YiFan Liu et al.   BIOMATERIALS

Study of the Correlation of Imipenem Resistance with Efflux Pumps AdeABC, AdeIJK, AdeDE and AbeM in Clinical Isolates of Acinetobacter baumannii

(2012) Pan Fei Hou et al.   CHEMOTHERAPY

Emerging trends in macromolecular antimicrobials to fight multi-drug-resistant infections

(2012) Amanda C. Engler et al.   Nano Today

Detection of Quorum Sensing Signal Molecules and Identification of an Autoinducer Synthase Gene among Biofilm Forming Clinical Isolates of Acinetobacter spp.

(2012) Deepa Anbazhagan et al.   PLoS One

Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells

(2012) E. I. Geihe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of thiol functional group incorporation into cationic helical peptides on antimicrobial activities and spectra

(2011) Nikken Wiradharma et al.   BIOMATERIALS

Highly dynamic biodegradable micelles capable of lysing Gram-positive and Gram-negative bacterial membrane

(2011) Yuan Qiao et al.   BIOMATERIALS

Biodegradable nanostructures with selective lysis of microbial membranes

(2011) Fredrik Nederberg et al.   Nature Chemistry

Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides

(2011) Gisela Lättig-Tünnemann et al.   Nature Communications

De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

(2009) Gregory N. Tew et al.   ACCOUNTS OF CHEMICAL RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Chemical Structure of Cationic Groups in Amphiphilic Polymethacrylates Modulates the Antimicrobial and Hemolytic Activities

(2009) Edmund F. Palermo et al.   BIOMACROMOLECULES

Structural Determinants of Antimicrobial Activity and Biocompatibility in Membrane-Disrupting Methacrylamide Random Copolymers

(2009) Edmund F. Palermo et al.   BIOMACROMOLECULES

Oligocarbonate Molecular Transporters: Oligomerization-Based Syntheses and Cell-Penetrating Studies

(2009) Christina B. Cooley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

(2009) S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties

(2008) Gregory J. Gabriel et al.   BIOMACROMOLECULES

Guanidinylated Dendritic Molecular Transporters: Prospective Drug Delivery Systems and Application in Cell Transfection

(2008) T. A. Theodossiou et al.   ChemMedChem

Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE

(2008) Louis B. Rice   JOURNAL OF INFECTIOUS DISEASES

Antimicrobial Polymers Prepared by ROMP with Unprecedented Selectivity: A Molecular Construction Kit Approach

(2008) Karen Lienkamp et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The design of guanidinium-rich transporters and their internalization mechanisms

(2007) Paul A. Wender et al.   ADVANCED DRUG DELIVERY REVIEWS

Tagging alcohols with cyclic carbonate: a versatile equivalent of (meth)acrylate for ring-opening polymerization

(2007) Russell C. Pratt et al.   CHEMICAL COMMUNICATIONS