Recent achievements and perspectives for large-scale recombinant production of antimicrobial peptides

Expression, Purification, and Characterization of a Novel Hybrid Peptide with Potent Antibacterial Activity

(2018) Xubiao Wei et al.   MOLECULES

Yeast-Based Synthetic Biology Platform for Antimicrobial Peptide Production

(2018) Jicong Cao et al.   ACS Synthetic Biology

Cost-effective downstream processing of recombinantly produced pexiganan peptide and its antimicrobial activity

(2018) Baode Sun et al.   AMB Express

Design and production of a novel antimicrobial fusion protein in Escherichia coli

(2018) Baode Sun et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genome Sequencing Reveals a Large and Diverse Repertoire of Antimicrobial Peptides

(2018) Reza Rezaei Javan et al.   Frontiers in Microbiology

Development of Silicone Hydrogel Antimicrobial Contact Lenses with Mel4 Peptide Coating

(2018) Debarun Dutta et al.   OPTOMETRY AND VISION SCIENCE

A high-throughput expression screening platform to optimize the production of antimicrobial peptides

(2017) Christine Schreiber et al.   Microbial Cell Factories

The heterologous expression strategies of antimicrobial peptides in microbial systems

(2017) Ting Deng et al.   PROTEIN EXPRESSION AND PURIFICATION

Recombinant expression, purification and antimicrobial activity of a novel antimicrobial peptide PaDef in Pichia pastoris

(2017) De-Mei Meng et al.   PROTEIN EXPRESSION AND PURIFICATION

Efficient biosynthesis of a Cecropin A-melittin mutant in Bacillus subtilis WB700

(2017) Shengyue Ji et al.   Scientific Reports

High-level heterologous production and Functional Secretion by recombinant Pichia pastoris of the shortest proline-rich antibacterial honeybee peptide Apidaecin

(2017) Ximing Chen et al.   Scientific Reports

An insight into fusion technology aiding efficient recombinant protein production for functional proteomics

(2016) Dinesh K. Yadav et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Non-chromatographic bioprocess engineering of a recombinant mineralizing protein for the synthesis of silica nanocapsules

(2016) David Wibowo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Antimicrobial peptides and wound healing: biological and therapeutic considerations

(2016) Maria Luisa Mangoni et al.   EXPERIMENTAL DERMATOLOGY

Production of a polar fish antimicrobial peptide in Escherichia coli using an ELP-intein tag

(2016) Daniel A. Sousa et al.   JOURNAL OF BIOTECHNOLOGY

Expression of a novel bacteriocin—the plantaricin Pln1—in Escherichia coli and its functional analysis

(2016) Fanqiang Meng et al.   PROTEIN EXPRESSION AND PURIFICATION

Higher efficiency soluble prokaryotic expression, purification, and structural analysis of antimicrobial peptide G13

(2016) Yuanyuan Che et al.   PROTEIN EXPRESSION AND PURIFICATION

Expression, purification and initial characterization of a novel recombinant antimicrobial peptide Mytichitin-A in Pichia pastoris

(2016) De-Mei Meng et al.   PROTEIN EXPRESSION AND PURIFICATION

Investigation of the automated solid-phase synthesis of a 38mer peptide with difficult sequence pattern under different synthesis strategies

(2015) Dirk F. H. Winkler et al.   AMINO ACIDS

In vitro and in vivo characterization of a new recombinant antimicrobial peptide, MP1102, against methicillin-resistant Staphylococcus aureus

(2015) Yong Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular chaperones (TrxA, SUMO, Intein, and GST) mediating expression, purification, and antimicrobial activity assays of plectasin inEscherichia coli

(2015) Xin Chen et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Improved strategy for recombinant production and purification of antimicrobial peptide tachyplesin I and its analogs with high cell selectivity

(2015) Pavel V. Panteleev et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

A simple and low-cost platform technology for producing pexiganan antimicrobial peptide in E. coli

(2015) Chun-Xia Zhao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Continuous downstream processing for high value biological products: A Review

(2015) Andrew L. Zydney   BIOTECHNOLOGY AND BIOENGINEERING

High-yield recombinant expression of the chicken antimicrobial peptide fowlicidin-2 inEscherichia coli

(2015) Xingjun Feng et al.   BIOTECHNOLOGY PROGRESS

Prokaryotic expression and mechanism of action of α-helical antimicrobial peptide A20L using fusion tags

(2015) Tonghui Yi et al.   BMC BIOTECHNOLOGY

Expression of plectasin in Bacillus subtilis using SUMO technology by a maltose-inducible vector

(2015) Licong Zhang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Interfacial Biomimetic Synthesis of Silica Nanocapsules Using a Recombinant Catalytic Modular Protein

(2015) David Wibowo et al.   LANGMUIR

Recombinant Production of Snakin-2 (an Antimicrobial Peptide from Tomato) in E. coli and Analysis of Its Bioactivity

(2015) Vera Herbel et al.   MOLECULES

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Scaling Up the Production of Recombinant Antimicrobial Plantaricin E from a Heterologous Host, Escherichia coli

(2015) Gargi Pal et al.   Probiotics and Antimicrobial Proteins

Sonorensin: an Antimicrobial Peptide, Belonging to the Heterocycloanthracin Subfamily of Bacteriocins, from a New Marine Isolate, Bacillus sonorensis MT93

(2014) Lipsy Chopra et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Considerations for the process development of insect-derived antimicrobial peptide production

(2014) Hagen Müller et al.   BIOTECHNOLOGY PROGRESS

Computational study of elements of stability of a four-helix bundle protein biosurfactant

(2014) Andrea Schaller et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Recombinant production of the antimicrobial peptide NZ17074 inPichia pastorisusing SUMO3 as a fusion partner

(2014) X.J. Wang et al.   LETTERS IN APPLIED MICROBIOLOGY

Recombinant Scorpine Produced Using SUMO Fusion Partner in Escherichia coli Has the Activities against Clinically Isolated Bacteria and Inhibits the Plasmodium falciparum Parasitemia In Vitro

(2014) Chao Zhang et al.   PLoS One

Recombinant expression, purification and characterization of antimicrobial peptide ORBK in Escherichia coli

(2014) Yan Li et al.   PROTEIN EXPRESSION AND PURIFICATION

Soluble prokaryotic expression and purification of crotamine using an N-terminal maltose-binding protein tag

(2014) Thu Trang Thi Vu et al.   TOXICON

Recombinant Production of Crab Antimicrobial Protein Scygonadin Expressed as Thioredoxin and SUMO Fusions in Escherichia coli

(2013) Yifeng Li   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Expressing antimicrobial peptide cathelicidin-BF in Bacillus subtilis using SUMO technology

(2013) Chao Luan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular Cloning, Recombinant Expression, and Antimicrobial Activity of EC-hepcidin3, a New Four-Cysteine Hepcidin Isoform fromEpinephelus coioides

(2013) HaiDong QU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Challenges and opportunities in the purification of recombinant tagged proteins

(2013) Ana Sofia Pina et al.   BIOTECHNOLOGY ADVANCES

Intensified expression and purification of a recombinant biosurfactant protein

(2013) Mirjana Dimitrijev Dwyer et al.   CHEMICAL ENGINEERING SCIENCE

Antimicrobial Gageomacrolactins Characterized from the Fermentation of the Marine-Derived Bacterium Bacillus subtilis under Optimum Growth Conditions

(2013) Fakir Shahidullah Tareq et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional Analysis via Expression in the Periplasm of E. coli

(2013) Julie K. Klint et al.   PLoS One

HETEROLOGOUS EXPRESSION AND PURIFICATION OF DERMASEPTIN S4 FUSION INEscherichia coliAND RECOVERY OF BIOLOGICAL ACTIVITY

(2013) Dafeng Song et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Construction and expression of an antimicrobial peptide scolopin 1 from the centipede venoms of Scolopendra subspinipes mutilans in Escherichia coli using SUMO fusion partner

(2013) Huanhuan Hou et al.   PROTEIN EXPRESSION AND PURIFICATION

Expression, purification and antibacterial activity of the channel catfish hepcidin mature peptide

(2013) Yan Tao et al.   PROTEIN EXPRESSION AND PURIFICATION

To fuse or not to fuse: What is your purpose?

(2013) Mark R. Bell et al.   PROTEIN SCIENCE

From antimicrobial to anticancer peptides. A review

(2013) Diana Gaspar et al.   Frontiers in Microbiology

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Molecular cloning and expression of ranalexin, a bioactive antimicrobial peptide from Rana catesbeiana in Escherichia coli and assessments of its biological activities

(2012) Rasha Abou Aleinein et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular Cloning, Expression, Purification, and Functional Characterization of Palustrin-2CE, an Antimicrobial Peptide ofRana chensinensis

(2012) Yan SUN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Recombinant protein expression and purification: A comprehensive review of affinity tags and microbial applications

(2012) Carissa L. Young et al.   Biotechnology Journal

Industrial production of recombinant therapeutics in Escherichia coli and its recent advancements

(2012) Chung-Jr Huang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Effects of Thioredoxin: SUMO and Intein on Soluble Fusion Expression of an Antimicrobial Peptide OG2 in Escherichia coli

(2012) Yong-Gang Xie et al.   PROTEIN AND PEPTIDE LETTERS

Production of human antimicrobial peptide LL-37 in Escherichia coli using a thioredoxin–SUMO dual fusion system

(2012) Yifeng Li   PROTEIN EXPRESSION AND PURIFICATION

Antimicrobial macromolecules: synthesis methods and future applications

(2012) Peng Li et al.   RSC Advances

Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development

(2011) Randal Eckert   Future Microbiology

A chromatography-focused bioprocess that eliminates soluble aggregation for bioactive production of a new antimicrobial peptide candidate

(2011) Xiang Li et al.   JOURNAL OF CHROMATOGRAPHY A

Recombinant production of antimicrobial peptides in Escherichia coli: A review

(2011) Yifeng Li   PROTEIN EXPRESSION AND PURIFICATION

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

Tethering antimicrobial peptides: Current status and potential challenges

(2010) Sagheer A. Onaizi et al.   BIOTECHNOLOGY ADVANCES

A new bioproduction route for a novel antimicrobial peptide

(2010) Derrick Kok Sing Tay et al.   BIOTECHNOLOGY AND BIOENGINEERING

Carrier proteins for fusion expression of antimicrobial peptides inEscherichia coli

(2009) Yifeng Li   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Chromatography-free recovery of biopharmaceuticals through aqueous two-phase processing

(2009) Ana M. Azevedo et al.   TRENDS IN BIOTECHNOLOGY

Thioredoxin as a fusion tag for carrier-driven crystallization

(2008) Lorenzo Corsini et al.   PROTEIN SCIENCE