Contribution of Dendritic Cell Responses to Sepsis-Induced Immunosuppression and to Susceptibility to Secondary Pneumonia

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

(2018) Djillali Annane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis

(2018) Lionel Franz Poulin et al.   Frontiers in Immunology

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

(2018) Ranin Beshara et al.   PLoS Pathogens

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections

(2017) Antoine Roquilly et al.   IMMUNITY

Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells

(2017) Linda Quatrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Christopher Troeger et al.   LANCET INFECTIOUS DISEASES

Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

(2016) Lonneke A. van Vught et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery

(2016) Laurence Ardouin et al.   IMMUNITY

Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

(2016) Lonneke A. van Vught et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Influenza A virus-induced release of interleukin-10 inhibits the anti-microbial activities of invariant natural killer T cells during invasive pneumococcal superinfection

(2016) A Barthelemy et al.   Mucosal Immunology

Exogenous Activation of Invariant Natural Killer T Cells by α-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza

(2016) Adeline Barthelemy et al.   mBio

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance

(2015) Myriam Baratin et al.   IMMUNITY

Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection

(2015) Michael H. Askenase et al.   IMMUNITY

Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response

(2015) Antoni Torres et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

XCR1+dendritic cells promote memory CD8+T cell recall upon secondary infections withListeria monocytogenesor certain viruses

(2015) Yannick O. Alexandre et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of dendritic cell alterations in susceptibility to hospital-acquired infections during critical-illness related immunosuppression

(2015) Antoine Roquilly et al.   MOLECULAR IMMUNOLOGY

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

(2015) Shruti Naik et al.   NATURE

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow

(2015) Andreas Schlitzer et al.   NATURE IMMUNOLOGY

Stress, the Stress System and the Role of Glucocorticoids

(2015) Nicolas C. Nicolaides et al.   NEUROIMMUNOMODULATION

Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis

(2015) Caiyi C. Li et al.   PLOS BIOLOGY

Investigating Evolutionary Conservation of Dendritic Cell Subset Identity and Functions

(2015) Thien-Phong Vu Manh et al.   Frontiers in Immunology

Hydrocortisone Prevents Immunosuppression by Interleukin-10+ Natural Killer Cells After Trauma-Hemorrhage

(2014) Antoine Roquilly et al.   CRITICAL CARE MEDICINE

Modulation of dendritic cell antigen presentation by pathogens, tissue damage and secondary inflammatory signals

(2014) Javier Vega-Ramos et al.   CURRENT OPINION IN PHARMACOLOGY

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

(2014) J. M. Marchingo et al.   SCIENCE

Hydrocortisone and fludrocortisone for prevention of hospital-acquired pneumonia in patients with severe traumatic brain injury (Corti-TC): a double-blind, multicentre phase 3, randomised placebo-controlled trial

(2014) Karim Asehnoune et al.   Lancet Respiratory Medicine

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Glucocorticoid receptor translational isoforms underlie maturational stage-specific glucocorticoid sensitivities of dendritic cells in mice and humans

(2013) Y. Cao et al.   BLOOD

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria

(2013) Alberto Pinzon-Charry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired Blood Dendritic Cell Numbers and Functions after Aneurysmal Subarachnoid Hemorrhage

(2013) Antoine Roquilly et al.   PLoS One

Inflammatory dendritic cells in mice and humans

(2013) Elodie Segura et al.   TRENDS IN IMMUNOLOGY

Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword

(2013) Amanda Gruver-Yates et al.   Cells

Innate Immune Dysfunction in Trauma Patients

(2012) Karim Asehnoune et al.   ANESTHESIOLOGY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

Consequences of direct and indirect activation of dendritic cells on antigen presentation: Functional implications and clinical considerations

(2012) Javier Vega-Ramos et al.   MOLECULAR IMMUNOLOGY

Deciphering the transcriptional network of the dendritic cell lineage

(2012) Jennifer C Miller et al.   NATURE IMMUNOLOGY

Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8

(2011) John J. Worthington et al.   GASTROENTEROLOGY

The Nasal Dendritic Cell-Targeting Flt3 Ligand as a Safe Adjuvant Elicits Effective Protection against Fatal Pneumococcal Pneumonia

(2011) Kosuke Kataoka et al.   INFECTION AND IMMUNITY

Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

(2011) D. Grimaldi et al.   INTENSIVE CARE MEDICINE

Hydrocortisone Therapy for Patients With Multiple Trauma

(2011) Antoine Roquilly   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

(2011) Jonathan S. Boomer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Tolerogenic function of Blimp-1 in dendritic cells

(2011) Sun Jung Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Skin-draining lymph nodes contain dermis-derived CD103- dendritic cells that constitutively produce retinoic acid and induce Foxp3+ regulatory T cells

(2010) M. Guilliams et al.   BLOOD

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

(2010) S. Gregori et al.   BLOOD

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Influenza Virus-Induced Glucocorticoids Compromise Innate Host Defense against a Secondary Bacterial Infection

(2010) Amanda M. Jamieson et al.   Cell Host & Microbe

Uptake of apoptotic DC converts immature DC into tolerogenic DC that induce differentiation of Foxp3+Treg

(2010) Rahul Kushwah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in mice

(2010) Julie Helft et al.   IMMUNOLOGICAL REVIEWS

IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection

(2010) Galit Alter et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of Dendritic Cell Differentiation in the Bone Marrow Mediates Sustained Immunosuppression after Polymicrobial Sepsis

(2010) E. Pastille et al.   JOURNAL OF IMMUNOLOGY

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell Apoptosis: Regulation of Tolerance versus Immunity

(2010) R. Kushwah et al.   JOURNAL OF IMMUNOLOGY

Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung

(2010) Cherrie-Lee Small et al.   JOURNAL OF IMMUNOLOGY

The role of the glucocorticoid receptor in inflammation and immunity

(2010) Ulrike Baschant et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Circulating dendritic cells following burn

(2009) N. D’Arpa et al.   BURNS

Systemic but Not Local Infections Elicit Immunosuppressive IL-10 Production by Natural Killer Cells

(2009) Georgia Perona-Wright et al.   Cell Host & Microbe

TNF-α induces TGF-β1expression in lung fibroblasts at the transcriptional levelviaAP-1 activation

(2009) Deborah E. Sullivan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TLR Triggering on Tolerogenic Dendritic Cells Results in TLR2 Up-Regulation and a Reduced Proinflammatory Immune Program

(2009) S. Chamorro et al.   JOURNAL OF IMMUNOLOGY

Absence of the Transcriptional Repressor Blimp-1 in Hematopoietic Lineages Reveals Its Role in Dendritic Cell Homeostatic Development and Function

(2009) Y.-H. Chan et al.   JOURNAL OF IMMUNOLOGY

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

(2008) Olivier Joffre et al.   IMMUNOLOGICAL REVIEWS

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

(2008) Scott H Robbins et al.   GENOME BIOLOGY