Bacteriophage delivering hydrogels reduce biofilm formation in vitro and infection in vivo

Implantable antimicrobial biomaterials for local drug delivery in bone infection models

(2019) Jeremy D. Caplin et al.   Acta Biomaterialia

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

(2019) Johanna M. Sweere et al.   SCIENCE

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Lysostaphin and BMP-2 co-delivery reduces S. aureus infection and regenerates critical-sized segmental bone defects

(2019) Christopher T. Johnson et al.   Science Advances

Hydrogel delivery of lysostaphin eliminates orthopedic implant infection byStaphylococcus aureusand supports fracture healing

(2018) Christopher T. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections

(2018) Rachit Agarwal et al.   Nature Biomedical Engineering

Mechanosensing of shear byPseudomonas aeruginosaleads to increased levels of the cyclic-di-GMP signal initiating biofilm development

(2017) Christopher A. Rodesney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

(2017) Sandra I. Berríos-Torres et al.   JAMA Surgery

Biomaterials approaches to treating implant-associated osteomyelitis

(2016) Jason A. Inzana et al.   BIOMATERIALS

Phage therapy of staphylococcal chronic osteomyelitis in experimental animal model

(2016) Gopal Nath et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

Integrin-specific hydrogels functionalized with VEGF for vascularization and bone regeneration of critical-size bone defects

(2016) José R. García et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

In Vivo Assessment of Phage and Linezolid Based Implant Coatings for Treatment of Methicillin Resistant S. aureus (MRSA) Mediated Orthopaedic Device Related Infections

(2016) Sandeep Kaur et al.   PLoS One

The role of microbial biofilms in prosthetic joint infections

(2014) Herbert O Gbejuade et al.   Acta Orthopaedica

Bacteriophage-Mediated Control of a Two-Species Biofilm Formed by Microorganisms Causing Catheter-Associated Urinary Tract Infections in anIn VitroUrinary Catheter Model

(2014) Susan M. Lehman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bone regeneration using an alpha 2 beta 1 integrin-specific hydrogel as a BMP-2 delivery vehicle

(2014) Asha Shekaran et al.   BIOMATERIALS

Biofilms in periprosthetic orthopedic infections

(2014) Stephen J McConoughey et al.   Future Microbiology

Bacteriophage Mediated Killing of Staphylococcus aureus In Vitro on Orthopaedic K Wires in Presence of Linezolid Prevents Implant Colonization

(2014) Sandeep Kaur et al.   PLoS One

Bacteriophage therapy of venous leg ulcers in humans: results of a phase I safety trial

(2014) D.D. Rhoads et al.   Journal of Wound Care

Reporting Surgical Site Infections Following Total Hip and Knee Arthroplasty: Impact of Limiting Surveillance to the Operative Hospital

(2013) Deborah S. Yokoe et al.   CLINICAL INFECTIOUS DISEASES

Bacteriophage Therapy in Implant-Related Infections

(2013) Cengiz Yilmaz et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

A historical overview of bacteriophage therapy as an alternative to antibiotics for the treatment of bacterial pathogens

(2013) Xavier Wittebole et al.   Virulence

The role of GlpR repressor inPseudomonas putidaKT2440 growth and PHA production from glycerol

(2012) I. F. Escapa et al.   ENVIRONMENTAL MICROBIOLOGY

Efficacy of Bacteriophage Treatment on Pseudomonas aeruginosa Biofilms

(2012) Alysen Phee et al.   JOURNAL OF ENDODONTICS

The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes

(2012) Rafael Silva-Rocha et al.   NUCLEIC ACIDS RESEARCH

Oral T4-like phage cocktail application to healthy adult volunteers from Bangladesh

(2012) Shafiqul Alam Sarker et al.   VIROLOGY

Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery

(2011) Edward A. Phelps et al.   ADVANCED MATERIALS

The efficacy and safety of antibiotic combination therapy for infections caused by Gram-positive and Gram-negative organisms

(2011) Mao Hagihara et al.   Expert Opinion On Drug Safety

The T7-Related Pseudomonas putida Phage φ15 Displays Virion-Associated Biofilm Degradation Properties

(2011) Anneleen Cornelissen et al.   PLoS One

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

The biofilm matrix

(2010) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Impact of multidrug-resistantPseudomonas aeruginosainfection on patient outcomes

(2010) Elizabeth B Hirsch et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System

(2009) W. Fu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

(2009) P. D. Lister et al.   CLINICAL MICROBIOLOGY REVIEWS

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

Evidence of Increasing Antibiotic Resistance Gene Abundances in Archived Soils since 1940

(2009) Charles W. Knapp et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Osteomyelitis and the role of biofilms in chronic infection

(2009) Rebecca A. Brady et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Quality-Controlled Small-Scale Production of a Well-Defined Bacteriophage Cocktail for Use in Human Clinical Trials

(2009) Maya Merabishvili et al.   PLoS One

Medical biofilms

(2008) James D. Bryers   BIOTECHNOLOGY AND BIOENGINEERING

Quorum sensing inPseudomonas aeruginosabiofilms

(2008) T. R. de Kievit   ENVIRONMENTAL MICROBIOLOGY

Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007

(2008) Alicia I. Hidron et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY