Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics
Authors
Keywords
Adaptive autophagy, Cell death, Cerebral I/R injury, Ischemic stroke, Maladaptive autophagy
Journal
PHARMACOLOGY & THERAPEUTICS
Volume 225, Issue -, Pages 107848
Publisher
Elsevier BV
Online
2021-04-04
DOI
10.1016/j.pharmthera.2021.107848
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dexmedetomidine post-conditioning ameliorates long-term neurological outcomes after neonatal hypoxic ischemia: The role of autophagy
- (2021) Hang Xue et al. LIFE SCIENCES
- ER stress in Cardiometabolic Diseases: from Molecular Mechanisms to Therapeutics
- (2021) Amir Ajoolabady et al. ENDOCRINE REVIEWS
- Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases
- (2021) Jun Ren et al. Nature Reviews Cardiology
- Thrombus Composition and Efficacy of Thrombolysis and Thrombectomy in Acute Ischemic Stroke
- (2021) Precious Jolugbo et al. STROKE
- Targeting autophagy in neurodegenerative diseases: From molecular mechanisms to clinical therapeutics
- (2021) Amir Ajoolabady et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Mechanistic Dissection of Sphingolipid Binding to the ER Stress Transducer ATF6 - Insights into the Coordination of Sphingolipid and Protein Production
- (2020) Toni Radanovic et al. BIOPHYSICAL JOURNAL
- Electroacupuncture Pretreatment Prevents Ischemic Stroke and Inhibits Wnt Signaling-Mediated Autophagy Through the Regulation of GSK-3β Phosphorylation
- (2020) Chengyu Chen et al. BRAIN RESEARCH BULLETIN
- Autophagy and disease: unanswered questions
- (2020) Ying Yang et al. CELL DEATH AND DIFFERENTIATION
- Autophagy as a Cellular Stress Response Mechanism in the Nervous System
- (2020) Nesibe Peker et al. JOURNAL OF MOLECULAR BIOLOGY
- Bone Marrow Stromal Cell Transplantation Drives Molecular Switch from Autophagy to the Ubiquitin-Proteasome System in Ischemic Stroke Mice
- (2020) Koh Tadokoro et al. Journal of Stroke & Cerebrovascular Diseases
- Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats
- (2020) Guoyuan Pan et al. LIFE SCIENCES
- MicroRNAs as major regulators of the autophagy pathway
- (2020) Yunus Akkoc et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Astrocyte-derived exosomes transfer miR-190b to inhibit oxygen and glucose deprivation-induced autophagy and neuronal apoptosis
- (2020) Xiaoxi Pei et al. CELL CYCLE
- VX‐765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke‐induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway
- (2020) Zhezhe Sun et al. CNS Neuroscience & Therapeutics
- Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy following Ischemic Brain Injury
- (2020) Claudia Espinosa-Garcia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mu-Xiang-You-Fang protects PC12 cells against OGD/R-induced autophagy via the AMPK/mTOR signaling pathway
- (2020) Hui-xia Ma et al. JOURNAL OF ETHNOPHARMACOLOGY
- Endurance exercise-induced expression of autophagy-related protein coincides with anabolic expression and neurogenesis in the hippocampus of the mouse brain
- (2020) Yongchul Jang NEUROREPORT
- Blockade of Nogo-A/Nogo-66 receptor 1 (NgR1) Inhibits Autophagic Activation and Prevents Secondary Neuronal Damage in the Thalamus after Focal Cerebral Infarction in Hypertensive Rats
- (2020) Wei Xu et al. NEUROSCIENCE
- Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke
- (2020) Man-Man Wang et al. Frontiers in Cellular Neuroscience
- Autophagy-mediated occludin degradation contributes to blood–brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models
- (2020) Kyeong-A Kim et al. Fluids and Barriers of the CNS
- Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway
- (2020) Zhi-Gang Mei et al. Aging-US
- Enzyme-based autophagy in anti-neoplastic management: From molecular mechanisms to clinical therapeutics
- (2020) Amir Ajoolabady et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Mechanisms underlying astrocytic connexin-43 autophagy degradation during cerebral ischemia injury and the effect on neuroinflammation and cell apoptosis
- (2020) Xinyu Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Dichloromethane extraction from Piper nigrum L. and P. longum L. to mitigate ischemic stroke by activating the AKT/mTOR signaling pathway to suppress autophagy
- (2020) Yiwei Zhang et al. BRAIN RESEARCH
- Geniposide inhibits NLRP3 inflammasome activation via autophagy in BV-2 microglial cells exposed to oxygen–glucose deprivation/reoxygenation
- (2020) Chen Fu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Nanomedicine for improvement of dendritic cell-based cancer immunotherapy
- (2020) Vida Hashemi et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- miR‑187‑3p inhibitor attenuates cerebral ischemia/reperfusion injury by regulating Seipin‑mediated autophagic flux
- (2020) Zhenkui Ren et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Role of Long Noncoding RNA MEG3/MiR-378/GRB2 Axis in Neuronal Autophagy and Neurological Functional Impairment in Ischemic Stroke
- (2020) Hong-Cheng Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calpain‐2 plays a pivotal role in the inhibitory effects of propofol against TNF‐α‐induced autophagy in mouse hippocampal neurons
- (2020) Ying Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Endurance Exercise-Induced Autophagy/Mitophagy Coincides with a Reinforced Anabolic State and Increased Mitochondrial Turnover in the Cortex of Young Male Mouse Brain
- (2020) Insu Kwon et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Compound K inhibits autophagy-mediated apoptosis induced by oxygen and glucose deprivation/reperfusion via regulating AMPK-mTOR pathway in neurons
- (2020) Qingxia Huang et al. LIFE SCIENCES
- Sodium Tanshinone IIA Sulfonate Protects Against Cerebral Ischemia–reperfusion Injury by Inhibiting Autophagy and Inflammation
- (2020) Lei Wang et al. NEUROSCIENCE
- FKBP5 Exacerbates Impairments in Cerebral Ischemic Stroke by Inducing Autophagy via the AKT/FOXO3 Pathway
- (2020) Shijia Yu et al. Frontiers in Cellular Neuroscience
- Exosomes Secreted From Bone Marrow Mesenchymal Stem Cells Attenuate Oxygen-Glucose Deprivation/Reoxygenation-Induced Pyroptosis in PC12 Cells by Promoting AMPK-Dependent Autophagic Flux
- (2020) Qing Zeng et al. Frontiers in Cellular Neuroscience
- Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke
- (2020) Yuguo Xia et al. Stem Cell Research & Therapy
- Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia
- (2020) Zelin Lai et al. Cell and Bioscience
- Role of Histone Deacetylases in Skeletal Muscle Physiology and Systemic Energy Homeostasis: Implications for Metabolic Diseases and Therapy
- (2020) Haili Tian et al. Frontiers in Physiology
- MicroRNA‐144 promotes remote limb ischemic preconditioning-mediated neuroprotection against ischemic stroke via PTEN/Akt pathway
- (2020) Si-Jin Zhong et al. ACTA NEUROLOGICA BELGICA
- Mitophagy Receptors and Mediators: Therapeutic Targets in the Management of Cardiovascular Ageing
- (2020) Amir Ajoolabady et al. AGEING RESEARCH REVIEWS
- MTMR14 protects against cerebral stroke through suppressing PTEN-regulated autophagy
- (2020) Qichen Pan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Anthocyanin ameliorates hypoxia and ischemia induced inflammation and apoptosis by increasing autophagic flux in SH-SY5Y cells
- (2020) Yiyu Cai et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- LncRNA SNHG3 promotes autophagy-induced neuronal cell apoptosis by acting as a ceRNA for miR-485 to up-regulate ATG7 expression
- (2020) Yanbin Cao et al. METABOLIC BRAIN DISEASE
- Autophagy in Human Diseases
- (2020) Noboru Mizushima et al. NEW ENGLAND JOURNAL OF MEDICINE
- FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity
- (2020) Jun Ren et al. Science Advances
- Targeting PTEN to regulate autophagy and promote the repair of injured neurons
- (2020) Haoyuan Yu et al. BRAIN RESEARCH BULLETIN
- Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy
- (2020) Xiande Ma et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats
- (2019) Xudong Chen et al. NEUROCHEMISTRY INTERNATIONAL
- Nucleic Acid Therapies for Ischemic Stroke
- (2019) Nils Henninger et al. Neurotherapeutics
- Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP+
- (2019) Wassamon Boonying et al. JOURNAL OF NEUROCHEMISTRY
- Regulation of autophagy as a therapy for immunosenescence-driven cancer and neurodegenerative diseases: The role of exercise
- (2019) Helena Angelica Pereira Batatinha et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Exercise activates lysosomal function in the brain through AMPK-SIRT1-TFEB pathway
- (2019) Jun Huang et al. CNS Neuroscience & Therapeutics
- S1PR1 as a Novel Promising Therapeutic Target in Cancer Therapy
- (2019) Narges Rostami et al. Molecular Diagnosis & Therapy
- The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy
- (2019) Yi Zhang et al. MOLECULES
- Dual Role of Autophagy in Diseases of the Central Nervous System
- (2019) Tamara Bar-Yosef et al. Frontiers in Cellular Neuroscience
- Sevoflurane post-conditioning alleviates neonatal rat hypoxic-ischemic cerebral injury via Ezh2-regulated autophagy
- (2019) Hang Xue et al. Drug Design Development and Therapy
- Physical exercise, autophagy and cardiometabolic stress in aging
- (2019) Haili Tian et al. Aging-US
- Mitochondrial ALDH2 protects against lipopolysaccharide-induced myocardial contractile dysfunction by suppression of ER stress and autophagy
- (2019) Jiaojiao Pang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury
- (2019) Ding-Mei Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Multifunctional nanomedicines for targeting epidermal growth factor receptor in colorectal cancer
- (2019) Mostafa Akbarzadeh Khiavi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats
- (2019) Yulin Zhu et al. INFLAMMATION
- Methylmercury exposure induces ROS/Akt inactivation-triggered endoplasmic reticulum stress-regulated neuronal cell apoptosis
- (2019) Yao-Pang Chung et al. TOXICOLOGY
- Propofol Attenuates α-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke
- (2019) Yuzhu Wang et al. Neuroscience Bulletin
- Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischemia/reperfusion injury by inhibiting GSK‐3 β ‐mediated activation of autophagy
- (2019) Jianmei Gao et al. BRITISH JOURNAL OF PHARMACOLOGY
- Resveratrol Activates Neuronal Autophagy Through AMPK in the Ischemic Brain
- (2019) Narayana Pineda-Ramírez et al. MOLECULAR NEUROBIOLOGY
- Dexmedetomidine Protects Against Oxygen–Glucose Deprivation-Induced Injury Through Inducing Astrocytes Autophagy via TSC2/mTOR Pathway
- (2019) Chen Zhu et al. NEUROMOLECULAR MEDICINE
- Physical Exercise and Selective Autophagy: Benefit and Risk on Cardiovascular Health
- (2019) Ne N. Wu et al. Cells
- Hyperbaric oxygen alleviated cognitive impairments in mice induced by repeated cerebral ischemia-reperfusion injury via inhibition of autophagy
- (2019) Chunxia Chen et al. LIFE SCIENCES
- MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro‐2a cells by targeting eIF4E-mediated induction of autophagy and inhibition of Akt/GSK-3β pathway
- (2019) Bing Li et al. MOLECULAR AND CELLULAR PROBES
- Role of autophagy and regulatory mechanisms in alcoholic cardiomyopathy
- (2018) Shuyi Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart
- (2018) Radka Cerychova et al. Cardiovascular Diabetology
- Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization
- (2018) Mei Jiang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- mTOR signaling in stem and progenitor cells
- (2018) Delong Meng et al. DEVELOPMENT
- Ezetimibe, a NPC1L1 inhibitor, attenuates neuronal apoptosis through AMPK dependent autophagy activation after MCAO in rats
- (2018) Jing Yu et al. EXPERIMENTAL NEUROLOGY
- XBP1 activation enhances MANF expression via binding to endoplasmic reticulum stress response elements within MANF promoter region in hepatitis B
- (2018) Dong Wang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Fisetin as a caloric restriction mimetic protects rat brain against aging induced oxidative stress, apoptosis and neurodegeneration
- (2018) Sandeep Singh et al. LIFE SCIENCES
- IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
- (2018) Hery Urra et al. NATURE CELL BIOLOGY
- Targeting autophagy in obesity: from pathophysiology to management
- (2018) Yingmei Zhang et al. Nature Reviews Endocrinology
- Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway
- (2018) Zhi-Gang Mei et al. Neural Regeneration Research
- Autophagy as an emerging target in cardiorenal metabolic disease: From pathophysiology to management
- (2018) Yingmei Zhang et al. PHARMACOLOGY & THERAPEUTICS
- bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
- (2018) Dawei Sun et al. Cell Death & Disease
- Possible Involvement of PTEN Signaling Pathway in the Anti-apoptotic Effect of Electroacupuncture Following Ischemic Stroke in Rats
- (2018) Ying Xing et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Role of autophagy in inherited metabolic and endocrine myopathies
- (2018) Ying Tan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Alterations of EDEM1 functions enhance ATF6 pro-survival signaling
- (2018) Alexandra Papaioannou et al. FEBS Journal
- Chitosan-based Nanotherapeutics for Ovarian Cancer Treatment
- (2018) Leila Alizadeh et al. JOURNAL OF DRUG TARGETING
- Propofol inhibited autophagy through Ca2+/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury
- (2018) Bei Sun et al. MOLECULAR MEDICINE
- Downregulation of autophagy by 12/15Lipoxygenase worsens the phenotype of an Alzheimer’s disease mouse model with plaques, tangles, and memory impairments
- (2018) Jian-Guo Li et al. MOLECULAR PSYCHIATRY
- Sevoflurane Postconditioning Inhibits Autophagy Through Activation of the Extracellular Signal-Regulated Kinase Cascade, Alleviating Hypoxic-Ischemic Brain Injury in Neonatal Rats
- (2018) Shuo Wang et al. NEUROCHEMICAL RESEARCH
- Targeting Autophagy in Aging and Aging-Related Cardiovascular Diseases
- (2018) Jun Ren et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Mutual inhibition between PTEN and PIP3 generates bistability for polarity in motile cells
- (2018) Satomi Matsuoka et al. Nature Communications
- Dexmedetomidine protects the developing rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1–Bax signaling
- (2018) Yangyang Shan et al. Drug Design Development and Therapy
- Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke
- (2018) Changjun Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Combination therapy with liposomal neuroprotectants and tissue plasminogen activator for treatment of ischemic stroke
- (2017) Tatsuya Fukuta et al. FASEB JOURNAL
- Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction
- (2017) Qi He et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Cortical spreading depression preconditioning mediates neuroprotection against ischemic stroke by inducing AMP-activated protein kinase-dependent autophagy in a rat cerebral ischemic/reperfusion injury model
- (2017) Pingping Shen et al. JOURNAL OF NEUROCHEMISTRY
- miR-30d-5p Plays an Important Role in Autophagy and Apoptosis in Developing Rat Brains After Hypoxic–Ischemic Injury
- (2017) Fengyan Zhao et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK and IRE1 signalings
- (2017) Dayun Feng et al. JOURNAL OF PINEAL RESEARCH
- Effects of mild running on substantia nigra during early neurodegeneration
- (2017) Michael F. Almeida et al. JOURNAL OF SPORTS SCIENCES
- Lysosomal Proteolysis Is Associated With Exercise-Induced Improvement of Mitochondrial Quality Control in Aged Hippocampus
- (2017) Li Luo et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Long noncoding RNA Malat1 is a potent autophagy inducer protecting brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury by sponging miR-26b and upregulating ULK2 expression
- (2017) Zhijun Li et al. NEUROSCIENCE
- Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes
- (2017) He Hongyun et al. NEUROSCIENCE LETTERS
- Retrograde signaling from autophagy modulates stress responses
- (2017) Hans-Uwe Simon et al. Science Signaling
- Dexmedetomidine Protects Mouse Brain from Ischemia-Reperfusion Injury via Inhibiting Neuronal Autophagy through Up-Regulating HIF-1α
- (2017) Cong Luo et al. Frontiers in Cellular Neuroscience
- mTOR/autophagy pathway in the hippocampus of rats suffering intermittent hypoxia preconditioning and global cerebral ischemia-reperfusion
- (2017) Ya-Ning Zhao et al. Oncotarget
- Retrograde signaling from autophagy modulates stress responses
- (2017) Hans-Uwe Simon et al. Science Signaling
- Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats
- (2017) Meiling Wu et al. Annals of Clinical and Translational Neurology
- Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation
- (2016) Marisa Ferreira-Marques et al. Aging-US
- Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die
- (2016) Jee-Yeon Hwang et al. CELL DEATH AND DIFFERENTIATION
- Valproic Acid Promotes Human Glioma U87 Cells Apoptosis and Inhibits Glycogen Synthase Kinase-3β Through ERK/Akt Signaling
- (2016) Chi Zhang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Prevention of Cyclophilin D-Mediated mPTP Opening Using Cyclosporine-A Alleviates the Elevation of Necroptosis, Autophagy and Apoptosis-Related Markers Following Global Cerebral Ischemia-Reperfusion
- (2016) Farinoosh Fakharnia et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Enhanced apoptosis from early physical exercise rehabilitation following ischemic stroke
- (2016) Fengwu Li et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Red Meat Consumption and the Risk of Stroke: A Dose–Response Meta-analysis of Prospective Cohort Studies
- (2016) Cuili Yang et al. Journal of Stroke & Cerebrovascular Diseases
- Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver
- (2016) Michael E. Fusakio et al. MOLECULAR BIOLOGY OF THE CELL
- Cerebral ischemic post-conditioning induces autophagy inhibition and a HMGB1 secretion attenuation feedback loop to protect against ischemia reperfusion injury in an oxygen glucose deprivation cellular model
- (2016) Jue Wang et al. Molecular Medicine Reports
- Autophagy in acute brain injury
- (2016) Lorenzo Galluzzi et al. NATURE REVIEWS NEUROSCIENCE
- Dynamic changes in neuronal autophagy and apoptosis in the ischemic penumbra following permanent ischemic stroke
- (2016) Peng-yue Zhang et al. Neural Regeneration Research
- Cyclic Compressive Stress Regulates Apoptosis in Rat Osteoblasts: Involvement of PI3K/Akt and JNK MAPK Signaling Pathways
- (2016) Fanglong Song et al. PLoS One
- Intermittent fasting is neuroprotective in focal cerebral ischemia by minimizing autophagic flux disturbance and inhibiting apoptosis
- (2016) Ji Heun Jeong et al. Experimental and Therapeutic Medicine
- Role and mechanism of the AMPK pathway in waterborne Zn exposure influencing the hepatic energy metabolism of Synechogobius hasta
- (2016) Kun Wu et al. Scientific Reports
- Red Meat Consumption and the Risk of Stroke: A Dose–Response Meta-analysis of Prospective Cohort Studies
- (2016) Cuili Yang et al. Journal of Stroke & Cerebrovascular Diseases
- Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling
- (2016) Jiaojiao Pang et al. PLoS One
- Activation of autophagy in human skeletal muscle is dependent on exercise intensity and AMPK activation
- (2015) Céline Schwalm et al. FASEB JOURNAL
- Too much or not enough of a good thing — The Janus faces of autophagy in cardiac fuel and protein homeostasis
- (2015) Jun Ren et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Metformin improves anxiety-like behaviors through AMPK-dependent regulation of autophagy following transient forebrain ischemia
- (2015) Alireza Sarkaki et al. METABOLIC BRAIN DISEASE
- Electroacupuncture pretreatment induces tolerance against cerebral ischemia/reperfusion injury through inhibition of the autophagy pathway
- (2015) ZHOUQUAN WU et al. Molecular Medicine Reports
- Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke
- (2015) Jeffrey L. Saver et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autophagic activity in neuronal cell death
- (2015) Robert W. Button et al. Neuroscience Bulletin
- Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice
- (2015) Guo-wen Hu et al. Stem Cell Research & Therapy
- Bcl-2 Phosphorylation Triggers Autophagy Switch and Reduces Mitochondrial Damage in Limb Remote Ischemic Conditioned Rats After Ischemic Stroke
- (2015) Zhifeng Qi et al. Translational Stroke Research
- Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells
- (2014) Hua Zhu et al. Autophagy
- Autophagy suppression by exercise pretreatment and p38 inhibition is neuroprotective in cerebral ischemia
- (2014) Li Zhang et al. BRAIN RESEARCH
- Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy
- (2014) Teng Jiang et al. BRITISH JOURNAL OF PHARMACOLOGY
- The mammalian tRNA ligase complex mediates splicing ofXBP1mRNA and controls antibody secretion in plasma cells
- (2014) Jennifer Jurkin et al. EMBO JOURNAL
- Physical Exercise Promotes Recovery of Neurological Function after Ischemic Stroke in Rats
- (2014) Hai-Qing Zheng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ischemic Preconditioning Provides Neuroprotection by Induction of AMP-Activated Protein Kinase-Dependent Autophagy in a Rat Model of Ischemic Stroke
- (2014) Teng Jiang et al. MOLECULAR NEUROBIOLOGY
- Pinocembrin Protects the Brain against Ischemia-Reperfusion Injury and Reverses the Autophagy Dysfunction in the Penumbra Area
- (2014) Gang Zhao et al. MOLECULES
- Thrombolysis and reperfusion: advanced understanding of early management strategies in acute ischemic stroke
- (2014) Dong Zhang et al. NEUROLOGICAL RESEARCH
- Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage
- (2014) Wei Zuo et al. NEUROPHARMACOLOGY
- Mechanisms of Acupuncture–Electroacupuncture on Persistent Pain
- (2013) Ruixin Zhang et al. ANESTHESIOLOGY
- Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance
- (2013) Xiangnan Zhang et al. Autophagy
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- ALDH2, a novel protector against stroke?
- (2013) Aijun Sun et al. CELL RESEARCH
- Commentary (Research Highlights: Linking Productive Autophagy to Neuroprotection: Potential Implications for Anti-Ischemic Therapy)
- (2013) G.K. Rajanikant et al. CNS & Neurological Disorders-Drug Targets
- Hypoxia-Inducible Factor and Vascular Endothelial Growth Factor Are Targets of Dietary Soy During Acute Stroke in Female Rats
- (2013) Yulin Ma et al. ENDOCRINOLOGY
- Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
- (2013) Michalis Papadakis et al. NATURE MEDICINE
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice
- (2013) W.-L. Li et al. NEUROSCIENCE
- Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-κB/p53 signaling pathway
- (2013) D.R. Cui et al. NEUROSCIENCE
- Electro-acupuncture at points of Zusanli and Quchi exerts anti-apoptotic effect through the modulation of PI3K/Akt signaling pathway
- (2013) Xiehua Xue et al. NEUROSCIENCE LETTERS
- Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia
- (2012) Pei Wang et al. Autophagy
- Exercise induces autophagy in peripheral tissues and in the brain
- (2012) Congcong He et al. Autophagy
- The end of autophagic cell death?
- (2012) Shensi Shen et al. Autophagy
- Anthocyanin Extracts from Black Soybean (Glycine max L.) Protect Human Glial Cells Against Oxygen-Glucose Deprivation by Promoting Autophagy
- (2012) Yong-Kwan Kim et al. Biomolecules & Therapeutics
- Excessive Autophagy Contributes to Neuron Death in Cerebral Ischemia
- (2012) Ruoyang Shi et al. CNS Neuroscience & Therapeutics
- A Double-Edged Sword with Therapeutic Potential: An Updated Role of Autophagy in Ischemic Cerebral Injury
- (2012) Kai Wei et al. CNS Neuroscience & Therapeutics
- Endoplasmic reticulum dysfunction in neurological disease
- (2012) Benoit D Roussel et al. LANCET NEUROLOGY
- Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
- (2012) Congcong He et al. NATURE
- Not just a rush of blood to the head
- (2012) Andrew J Brumm et al. NATURE MEDICINE
- Functional recovery after ischemic stroke--A matter of age: Data from the Austrian Stroke Unit Registry
- (2012) M. Knoflach et al. NEUROLOGY
- Inhibition of Autophagy Contributes to Ischemic Postconditioning-Induced Neuroprotection against Focal Cerebral Ischemia in Rats
- (2012) Li Gao et al. PLoS One
- Dietary Flavonoids and Risk of Stroke in Women
- (2012) Aedín Cassidy et al. STROKE
- Regulation and Function of Autophagy during Cell Survival and Cell Death
- (2012) G. Das et al. Cold Spring Harbor Perspectives in Biology
- Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan
- (2011) Rochele Yamamoto et al. AGING CELL
- Mediterranean-style diet and risk of ischemic stroke, myocardial infarction, and vascular death: the Northern Manhattan Study
- (2011) Hannah Gardener et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Intranasal Ginsenoside Rb1 Targets the Brain and Ameliorates Cerebral Ischemia/Reperfusion Injury in Rats
- (2011) Tingting Lu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Autophagy activation is involved in neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats
- (2011) Wenjun Yan et al. BRAIN RESEARCH
- The Beclin 1 network regulates autophagy and apoptosis
- (2011) R Kang et al. CELL DEATH AND DIFFERENTIATION
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
- (2011) L Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Autophagy-related and autophagy-regulatory genes are induced in human muscle after ultraendurance exercise
- (2011) Cécile Jamart et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Occludin: One Protein, Many Forms
- (2011) P. M. Cummins MOLECULAR AND CELLULAR BIOLOGY
- Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia
- (2010) Ai-Ping Qin et al. Autophagy
- Short-term fasting induces profound neuronal autophagy
- (2010) Mehrdad Alirezaei et al. Autophagy
- Novel Hemostatic Factor Levels and Risk of Ischemic Stroke: The Atherosclerosis Risk in Communities (ARIC) Study
- (2010) M. Fareed K. Suri et al. CEREBROVASCULAR DISEASES
- Lysosome Dysfunction Triggers Atg7-dependent Neural Apoptosis
- (2010) Ken C. Walls et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
- (2010) You-Tong Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuronal Gap Junctions Are Required for NMDA Receptor–Mediated Excitotoxicity: Implications in Ischemic Stroke
- (2010) Yongfu Wang et al. JOURNAL OF NEUROPHYSIOLOGY
- Total Antioxidant Capacity of the Diet Is Associated with Lower Risk of Ischemic Stroke in a Large Italian Cohort
- (2010) Daniele Del Rio et al. JOURNAL OF NUTRITION
- Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis
- (2010) B. Y. K. Law et al. MOLECULAR CANCER THERAPEUTICS
- Ischemic stroke in the elderly: an overview of evidence
- (2010) Ruo-Li Chen et al. Nature Reviews Neurology
- The Science of Stroke: Mechanisms in Search of Treatments
- (2010) Michael A. Moskowitz et al. NEURON
- Vascular Endothelial Growth Factor Receptor-2 Inhibition Promotes Cell Death and Limits Endothelial Cell Proliferation in a Neonatal Rodent Model of Stroke
- (2010) Janet Shimotake et al. STROKE
- AMPK-Dependent Metabolic Regulation by PPAR Agonists
- (2010) Woo Hyung Lee et al. PPAR Research
- Serum and Dietary Magnesium and Risk of Ischemic Stroke: The Atherosclerosis Risk in Communities Study
- (2009) T. Ohira et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Enhancement of Autophagic Flux after Neonatal Cerebral Hypoxia-Ischemia and Its Region-Specific Relationship to Apoptotic Mechanisms
- (2009) Vanessa Ginet et al. AMERICAN JOURNAL OF PATHOLOGY
- Fast food and neighborhood stroke risk
- (2009) Lewis B. Morgenstern et al. ANNALS OF NEUROLOGY
- Autophagy in Ischemic Heart Disease
- (2009) Åsa B. Gustafsson et al. CIRCULATION RESEARCH
- Dairy Foods and Risk of Stroke
- (2009) Susanna C. Larsson et al. EPIDEMIOLOGY
- Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca2+ homeostasis
- (2009) Jinhua Shen et al. NATURE CELL BIOLOGY
- Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia
- (2009) Hong-Shuo Sun et al. NATURE NEUROSCIENCE
- Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury
- (2008) Masato Koike et al. AMERICAN JOURNAL OF PATHOLOGY
- Most mammalian mRNAs are conserved targets of microRNAs
- (2008) R. C. Friedman et al. GENOME RESEARCH
- The eIF4E RNA regulon promotes the Akt signaling pathway
- (2008) Biljana Culjkovic et al. JOURNAL OF CELL BIOLOGY
- Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
- (2008) Eisuke Itakura et al. MOLECULAR BIOLOGY OF THE CELL
- Mitochondrial Respiratory Dysfunction in Familiar Parkinsonism Associated with PINK1 Mutation
- (2008) Claudia Piccoli et al. NEUROCHEMICAL RESEARCH
- Lysosomal myopathies: An excessive build-up in autophagosomes is too much to handle
- (2008) May Christine Malicdan et al. NEUROMUSCULAR DISORDERS
- Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death
- (2007) A. Rami et al. NEUROBIOLOGY OF DISEASE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now