Propofol Attenuates α-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke

Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease

(2018) Diego Grassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy in ischemic stroke

(2018) Pei Wang et al.   PROGRESS IN NEUROBIOLOGY

Trapping of Syntaxin1a in Presynaptic Nanoclusters by a Clinically Relevant General Anesthetic

(2018) Adekunle T. Bademosi et al.   Cell Reports

Accumulation of autophagosomes confers cytotoxicity

(2017) Robert W. Button et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotective and regenerative roles of intranasal Wnt-3a administration after focal ischemic stroke in mice

(2017) Zheng Zachory Wei et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

(2017) Yvette C Wong et al.   NATURE MEDICINE

Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice

(2017) Mingke Song et al.   NEUROBIOLOGY OF DISEASE

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

Mitochondrial function in hypoxic ischemic injury and influence of aging

(2017) P. Benson Ham et al.   PROGRESS IN NEUROBIOLOGY

Pink1 interacts with α-synuclein and abrogates α-synuclein-induced neurotoxicity by activating autophagy

(2017) Jia Liu et al.   Cell Death & Disease

Precise Cerebral Vascular Atlas in Stereotaxic Coordinates of Whole Mouse Brain

(2017) Benyi Xiong et al.   Frontiers in Neuroanatomy

Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease

(2017) Thomas Geuens et al.   Acta Neuropathologica Communications

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease

(2016) Joana Magalhaes et al.   HUMAN MOLECULAR GENETICS

Poststroke Induction of  -Synuclein Mediates Ischemic Brain Damage

(2016) T. Kim et al.   JOURNAL OF NEUROSCIENCE

Propofol Suppressed Hypoxia/Reoxygenation-Induced Apoptosis in HBVSMC by Regulation of the Expression of Bcl-2, Bax, Caspase3, Kir6.1, and p-JNK

(2016) Jianhai Zhang et al.   Oxidative Medicine and Cellular Longevity

Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites

(2016) Andres Binolfi et al.   Nature Communications

NADPH Oxidase 4 Induces Cardiac Fibrosis and Hypertrophy Through Activating Akt/mTOR and NF B Signaling Pathways

(2015) Q. D. Zhao et al.   CIRCULATION

Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling

(2015) Shanshan Gao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Fibrillar α-Synuclein and Huntingtin Exon 1 Assemblies Are Toxic to the Cells

(2012) Laura Pieri et al.   BIOPHYSICAL JOURNAL

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation

(2012) M. J. Diogenes et al.   JOURNAL OF NEUROSCIENCE

Barrel cortex function

(2012) Dirk Feldmeyer et al.   PROGRESS IN NEUROBIOLOGY

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

(2011) Tim Bartels et al.   NATURE

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alpha-Synuclein Aggregation Induced by Brief Ischemia Negatively Impacts Neuronal Survival in vivo: A Study in [A30P]alpha-Synuclein Transgenic Mouse

(2010) Isin Unal-Cevik et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE