Cyclic Compressive Stress Regulates Apoptosis in Rat Osteoblasts: Involvement of PI3K/Akt and JNK MAPK Signaling Pathways

A novel role for integrin-linked kinase in periodic mechanical stress-mediated ERK1/2 mitogenic signaling in rat chondrocytes

(2016) Huanghe Song et al.   CELL BIOLOGY INTERNATIONAL

Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways

(2016) Geng Bin et al.   EXPERIMENTAL CELL RESEARCH

Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway

(2016) Candice G. T. Tahimic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beta1 integrin inhibits apoptosis induced by cyclic stretch in annulus fibrosus cells via ERK1/2 MAPK pathway

(2015) Kai Zhang et al.   APOPTOSIS

Compromised MAPK signaling in human diseases: an update

(2015) Eun Kyung Kim et al.   ARCHIVES OF TOXICOLOGY

Fluid shear stress inhibits TNF-α-induced osteoblast apoptosis via ERK5 signaling pathway

(2015) Geng Bin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Orbital fluid shear stress promotes osteoblast metabolism, proliferation and alkaline phosphates activity in vitro

(2015) M.D. Aisha et al.   EXPERIMENTAL CELL RESEARCH

A Time to Kill: Targeting Apoptosis in Cancer

(2015) Jean Koff et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of Osteocyte Apoptosis Prevents the Increase in Osteocytic Receptor Activator of Nuclear Factor κB Ligand (RANKL) but Does Not Stop Bone Resorption or the Loss of Bone Induced by Unloading

(2015) Lilian I. Plotkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanical Stimulation and IGF-1 Enhance mRNA Translation Rate in Osteoblasts Via Activation of the AKT-mTOR Pathway

(2015) Astrid D. Bakker et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cell Death Signaling

(2015) Douglas R. Green et al.   Cold Spring Harbor Perspectives in Biology

Mechanical Stretch Induces Apoptosis Regulator TRB3 in Cultured Cardiomyocytes and Volume-Overloaded Heart

(2015) Wen-Pin Cheng et al.   PLoS One

Mechanical Loading Synergistically Increases Trabecular Bone Volume and Improves Mechanical Properties in the Mouse when BMP Signaling Is Specifically Ablated in Osteoblasts

(2015) Ayaka Iura et al.   PLoS One

The Expression of Fn14 via Mechanical Stress-activated JNK Contributes to Apoptosis Induction in Osteoblasts

(2014) Hiroyuki Matsui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New Method to Investigate How Mechanical Loading of Osteocytes Controls Osteoblasts

(2014) Marisol Vazquez et al.   Frontiers in Endocrinology

Dysapoptosis of Osteoblasts and Osteocytes Increases Cancellous Bone Formation But Exaggerates Cortical Porosity With Age

(2013) Robert L Jilka et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Isoformononetin, a methoxydaidzein present in medicinal plants, reverses bone loss in osteopenic rats and exerts bone anabolic action by preventing osteoblast apoptosis

(2013) K. Srivastava et al.   PHYTOMEDICINE

Static Mechanical Stress Induces Apoptosis in Rat Endplate Chondrocytes through MAPK and Mitochondria-Dependent Caspase Activation Signaling Pathways

(2013) Dechao Kong et al.   PLoS One

Pathological Cyclic Strain-Induced Apoptosis in Human Periodontal Ligament Cells through the RhoGDIα/Caspase-3/PARP Pathway

(2013) Li Wang et al.   PLoS One

Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer

(2013) Long Zhang et al.   TRENDS IN BIOCHEMICAL SCIENCES

ERK5: Structure, regulation and function

(2012) Gopika N. Nithianandarajah-Jones et al.   CELLULAR SIGNALLING

MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells

(2012) Li Yuan et al.   FOOD AND CHEMICAL TOXICOLOGY

Static mechanical stretching accelerates lipid production in 3T3-L1 adipocytes by activating the MEK signaling pathway

(2011) Naama Shoham et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Apoptosis Signaling Kinases: From Stress Response to Health Outcomes

(2010) Kohsuke Takeda et al.   ANTIOXIDANTS & REDOX SIGNALING

The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo

(2010) Scott Ackler et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Mechanical signals as anabolic agents in bone

(2010) Engin Ozcivici et al.   Nature Reviews Rheumatology

Cyclic stretching force-induced early apoptosis in human periodontal ligament cells

(2008) W Zhong et al.   ORAL DISEASES

Compressive force stimulates the expression of osteogenesis-related transcription factors in ROS 17/2.8 cells

(2007) Momoko Yanagisawa et al.   ARCHIVES OF ORAL BIOLOGY