Downregulation of autophagy by 12/15Lipoxygenase worsens the phenotype of an Alzheimer’s disease mouse model with plaques, tangles, and memory impairments

Neuroinflammation in Alzheimer’s disease: Pleiotropic roles for cytokines and neuronal pentraxins

(2018) Ashley Swanson et al.   BEHAVIOURAL BRAIN RESEARCH

Alzheimer’s Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies—Gains from AIBL and DIAN Cohort Studies

(2018) Ralph N. Martins et al.   JOURNAL OF ALZHEIMERS DISEASE

A Long Journey into Aging, Brain Aging, and Alzheimer’s Disease Following the Oxidative Stress Tracks

(2018) Patrizia Mecocci et al.   JOURNAL OF ALZHEIMERS DISEASE

Reactive astrocytes in Alzheimer’s disease: A double-edged sword

(2018) Heejung Chun et al.   NEUROSCIENCE RESEARCH

Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology

(2017) Jian-Guo Li et al.   HUMAN MOLECULAR GENETICS

The direct role of 5-lipoxygenase on tau pathology, synaptic integrity and cognition in a mouse model of tauopathy

(2017) Alana N. Vagnozzi et al.   Translational Psychiatry

Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective

(2017) Rodrigo E. González-Reyes et al.   Frontiers in Molecular Neuroscience

Extra-virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy

(2017) Elisabetta Lauretti et al.   Annals of Clinical and Translational Neurology

Synaptic pathology: A shared mechanism in neurological disease

(2016) Christopher M. Henstridge et al.   AGEING RESEARCH REVIEWS

Pharmacologic Inhibition of 5-Lipoxygenase Improves Memory, Rescues Synaptic Dysfunction, and Ameliorates Tau Pathology in a Transgenic Model of Tauopathy

(2015) Phillip F. Giannopoulos et al.   BIOLOGICAL PSYCHIATRY

Maternal dexamethasone exposure ameliorates cognition and tau pathology in the offspring of triple transgenic AD mice

(2015) A Di Meco et al.   MOLECULAR PSYCHIATRY

Autophagy in Alzheimer’s disease

(2015) Ameneh Zare-shahabadi et al.   REVIEWS IN THE NEUROSCIENCES

The 12/15-lipoxygenase as an emerging therapeutic target for Alzheimer's disease

(2015) Yash B. Joshi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimer’s disease phenotype

(2015) Yash B. Joshi et al.   Frontiers in Cellular Neuroscience

A novel role for 12/15-lipoxygenase in regulating autophagy

(2015) Alwena H. Morgan et al.   Redox Biology

The role of lipoxygenases in pathophysiology; new insights and future perspectives

(2015) Ryuichi Mashima et al.   Redox Biology

Behavioral assays with mouse models of Alzheimer's disease: Practical considerations and guidelines

(2014) Daniela Puzzo et al.   BIOCHEMICAL PHARMACOLOGY

Novel lipid signaling pathways in Alzheimer's disease pathogenesis

(2013) Phillip F. Giannopoulos et al.   BIOCHEMICAL PHARMACOLOGY

Genetic ablation and short-duration inhibition of lipoxygenase results in increased macroautophagy

(2013) Insook Jang et al.   EXPERIMENTAL CELL RESEARCH

5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease

(2012) Jin Chu et al.   ANNALS OF NEUROLOGY

Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice

(2012) Jin Chu et al.   Molecular Neurodegeneration

Transcriptional regulation of βsecretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments

(2011) Jin Chu et al.   ANNALS OF NEUROLOGY

Amelioration of the Alzheimer's Disease Phenotype by Absence of 12/15-Lipoxygenase

(2010) Hengxuan Yang et al.   BIOLOGICAL PSYCHIATRY

Alzheimer’s Disease Amyloid β-Protein and Synaptic Function

(2009) Tomas Ondrejcak et al.   NEUROMOLECULAR MEDICINE