VX‐765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke‐induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway
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Title
VX‐765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke‐induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway
Authors
Keywords
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Journal
CNS Neuroscience & Therapeutics
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-05-27
DOI
10.1111/cns.13400
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Note: Only part of the references are listed.- Caspase-1 inhibition mediates neuroprotection in experimental stroke by polarizing M2 microglia/macrophage and suppressing NF-κB activation
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- (2018) Helison Do Carmo et al. CARDIOVASCULAR DRUGS AND THERAPY
- The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke
- (2018) Catriona J Cunningham et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo
- (2018) Wei Liu et al. Journal of Neuroinflammation
- Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
- (2018) Brienne A. McKenzie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy in ischemic stroke
- (2018) Pei Wang et al. PROGRESS IN NEUROBIOLOGY
- Global Burden of Stroke
- (2018) Mira Katan et al. SEMINARS IN NEUROLOGY
- Potential of Stem Cell-Based Therapy for Ischemic Stroke
- (2018) Hany E. Marei et al. Frontiers in Neurology
- Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model
- (2018) Joseph Flores et al. Nature Communications
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- (2017) Joshua D Bernstock et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke
- (2017) Ling Wei et al. PROGRESS IN NEUROBIOLOGY
- Macrophage migration inhibitory factor induces autophagy to resist hypoxia/serum deprivation-induced apoptosis via the AMP-activated protein kinase/mammalian target of rapamycin signaling pathway
- (2016) WENZHENG XIA et al. Molecular Medicine Reports
- Inflammation and Stroke: An Overview
- (2016) Josef Anrather et al. Neurotherapeutics
- The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells
- (2016) Francesca Vittoria Sbrana et al. Stem Cell Reviews and Reports
- The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells
- (2016) Francesca Vittoria Sbrana et al. Stem Cell Reviews and Reports
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- Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments
- (2015) Paul M. George et al. NEURON
- Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke
- (2015) Mayank Goyal et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2015) Yuchen Feng et al. TRENDS IN CELL BIOLOGY
- Mannitol-Enhanced Delivery of Stem Cells and Their Growth Factors across the Blood–Brain Barrier
- (2014) Gabriel S. Gonzales-Portillo et al. CELL TRANSPLANTATION
- Ischemic Preconditioning Provides Neuroprotection by Induction of AMP-Activated Protein Kinase-Dependent Autophagy in a Rat Model of Ischemic Stroke
- (2014) Teng Jiang et al. MOLECULAR NEUROBIOLOGY
- Macrophage migration inhibitory factor plays a permissive role in the maintenance of cardiac contractile function under starvation through regulation of autophagy
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- Stromal Cell-Derived Factor-1β Mediates Cell Survival through Enhancing Autophagy in Bone Marrow-Derived Mesenchymal Stem Cells
- (2013) Samuel Herberg et al. PLoS One
- Permeating the Blood Brain Barrier and Abrogating the Inflammation in Stroke: Implications for Stroke Therapy
- (2012) Cesar V. Borlongan et al. CURRENT PHARMACEUTICAL DESIGN
- Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)
- (2012) Meir Bialer et al. EPILEPSY RESEARCH
- Macrophage Migration Inhibitory Factor Induces Autophagy via Reactive Oxygen Species Generation
- (2012) Yung-Chun Chuang et al. PLoS One
- Autophagy Activation: A Novel Mechanism of Atorvastatin to Protect Mesenchymal Stem Cells from Hypoxia and Serum Deprivation via AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway
- (2012) Qian Zhang et al. STEM CELLS AND DEVELOPMENT
- Autophagy Regulation and Integration with Cell Signaling
- (2011) Anne Hamacher-Brady ANTIOXIDANTS & REDOX SIGNALING
- Human Umbilical Mesenchymal Stem Cells Promote Recovery After Ischemic Stroke
- (2011) Yu-Ching Lin et al. STROKE
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- (2010) Paul R. Sanberg et al. CELL TRANSPLANTATION
- A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety
- (2010) Matthew B. Boxer et al. ChemMedChem
- Mannitol facilitates neurotrophic factor up-regulation and behavioural recovery in neonatal hypoxic-ischaemic rats with human umbilical cord blood grafts
- (2009) T. Yasuhara et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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