Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver
Authors
Keywords
-
Journal
MOLECULAR BIOLOGY OF THE CELL
Volume 27, Issue 9, Pages 1536-1551
Publisher
American Society for Cell Biology (ASCB)
Online
2016-03-10
DOI
10.1091/mbc.e16-01-0039
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4
- (2015) Christopher J. Huggins et al. MOLECULAR AND CELLULAR BIOLOGY
- Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα
- (2014) Thomas D. Baird et al. MOLECULAR BIOLOGY OF THE CELL
- Regulatory crosstalk within the mammalian unfolded protein response
- (2013) Joseph W. Brewer CELLULAR AND MOLECULAR LIFE SCIENCES
- ATF4 Protein Deficiency Protects against High Fructose-induced Hypertriglyceridemia in Mice
- (2013) Guozhi Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells
- (2013) Clemens Röhrl et al. JOURNAL OF LIPID RESEARCH
- CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis
- (2013) Brian F. Teske et al. MOLECULAR BIOLOGY OF THE CELL
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation
- (2012) Ana Luísa De Sousa-Coelho et al. BIOCHEMICAL JOURNAL
- The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling
- (2012) Suneng Fu et al. Cell Metabolism
- Fibroblast Growth Factor 21 as an emerging metabolic regulator: clinical perspectives
- (2012) Y. C. Woo et al. CLINICAL ENDOCRINOLOGY
- Stress-induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy
- (2012) Scott M. Ebert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase
- (2012) Jeffrey G. Dickhout et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Receptors HNF4α and LRH-1 Cooperate in RegulatingCyp7a1 in Vivo
- (2012) Serkan Kir et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2012) Cole Trapnell et al. Nature Protocols
- PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees
- (2012) Huaiyu Mi et al. NUCLEIC ACIDS RESEARCH
- Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice
- (2012) W. Peng et al. Science Translational Medicine
- Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism
- (2012) Thomas D. Baird et al. Advances in Nutrition
- The Transcription Factor Network Associated With the Amino Acid Response in Mammalian Cells
- (2012) Michael S. Kilberg et al. Advances in Nutrition
- The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
- (2011) Brian F. Teske et al. MOLECULAR BIOLOGY OF THE CELL
- The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α
- (2011) Claudio Hetz et al. PHYSIOLOGICAL REVIEWS
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- The binary switch that controls the life and death decisions of ER stressed β cells
- (2010) Christine M Oslowski et al. CURRENT OPINION IN CELL BIOLOGY
- Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response
- (2010) Souvik Dey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
- (2010) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- TopHat: discovering splice junctions with RNA-Seq
- (2009) Cole Trapnell et al. BIOINFORMATICS
- GCN2 Protein Kinase Is Required to Activate Amino Acid Deprivation Responses in Mice Treated with the Anti-cancer Agent l-Asparaginase
- (2009) Piyawan Bunpo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Divergent Effects of PERK and IRE1 Signaling on Cell Viability
- (2009) Jonathan H. Lin et al. PLoS One
- Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
- (2009) Heather P. Harding et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response
- (2009) M. S. Sundrud et al. SCIENCE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- C/EBP Homology Protein (CHOP) Interacts with Activating Transcription Factor 4 (ATF4) and Negatively Regulates the Stress-dependent Induction of the Asparagine Synthetase Gene
- (2008) Nan Su et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport
- (2008) Bin Zhao et al. JOURNAL OF LIPID RESEARCH
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started