The Role of the BH4 Cofactor in Nitric Oxide Synthase Activity and Cancer Progression: Two Sides of the Same Coin

Novel Insights Regarding Nitric Oxide and Cardiovascular Diseases

(2021) Teresa Infante et al.   ANGIOLOGY

Vorinostat exhibits anticancer effects in triple-negative breast cancer cells by preventing nitric oxide-driven histone deacetylation

(2021) Marianne B. Palczewski et al.   BIOLOGICAL CHEMISTRY

Autism: Screening of inborn errors of metabolism and unexpected results

(2021) Aslı İnci et al.   Autism Research

Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates

(2021) Shaimaa M. Badr-Eldin et al.   Frontiers in Pharmacology

Tumor-associated Stromal Cellular Density as a Predictor of Recurrence and Mortality in Breast Cancer: Results from Ethnically-diverse Study Populations

(2021) Mustapha Abubakar et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis

(2021) Guo-Chao Zhong et al.   FREE RADICAL BIOLOGY AND MEDICINE

mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications

(2021) Bashir Lawal et al.   Frontiers in Oncology

Characterising the Response of Human Breast Cancer Cells to Polyamine Modulation

(2021) Oluwaseun Akinyele et al.   Biomolecules

Vascular normalization in immunotherapy: A promising mechanisms combined with radiotherapy

(2021) Zijing Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Mitophagy in carcinogenesis, drug resistance and anticancer therapeutics

(2021) Yanjie Guan et al.   Cancer Cell International

TGF-β Signaling: From Tissue Fibrosis to Tumor Microenvironment

(2021) Jeff Yat-Fai Chung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Planning for tomorrow: global cancer incidence and the role of prevention 2020–2070

(2021) Isabelle Soerjomataram et al.   Nature Reviews Clinical Oncology

Anti-angiogenesis Revisited: Combination with Immunotherapy in Solid Tumors

(2021) Alex Chambers et al.   Current Oncology Reports

Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging

(2021) EunJin Bang et al.   Redox Biology

The Anti-VEGF(R) Drug Discovery Legacy: Improving Attrition Rates by Breaking the Vicious Cycle of Angiogenesis in Cancer

(2021) Domenico Ribatti et al.   Cancers

NOX4 Signaling Mediates Cancer Development and Therapeutic Resistance through HER3 in Ovarian Cancer Cells

(2021) Wen-Jing Liu et al.   Cells

Ferroptosis-Related Gene Signature Promotes Ovarian Cancer by Influencing Immune Infiltration and Invasion

(2021) Yang You et al.   Journal of Oncology

Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling

(2021) Zhaodong Ji et al.   Frontiers in Cell and Developmental Biology

NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology

(2021) Annelise Vermot et al.   Antioxidants

Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals distinct cancer-associated fibroblasts in head and neck squamous cell carcinoma

(2021) Qian Zhang et al.   Annals of Translational Medicine

Correction of arginine metabolism with sepiapterin—the precursor of nitric oxide synthase cofactor BH4—induces immunostimulatory-shift of breast cancer

(2020) Xunzhen Zheng et al.   BIOCHEMICAL PHARMACOLOGY

Association of NOS3 and ANGPT2 gene polymorphisms with survival in patients with hepatocellular carcinoma receiving sorafenib: results of the multicenter prospective INNOVATE study

(2020) Andrea Casadei Gardini et al.   CLINICAL CANCER RESEARCH

Nitric oxide donors as potential drugs for the treatment of vascular diseases due to endothelium dysfunction.

(2020) Michele Paulo et al.   CURRENT PHARMACEUTICAL DESIGN

Direct Current Electric Field Stimulates Nitric Oxide Production and Promotes NO-Dependent Angiogenesis: Involvement of the PI3K/Akt Signaling Pathway

(2020) Xing Wei et al.   JOURNAL OF VASCULAR RESEARCH

Shear Stress Triggers Angiogenesis of Late Endothelial Progenitor Cells via the PTEN/Akt/GTPCH/BH4 Pathway

(2020) Shao-Hong Wu et al.   Stem Cells International

Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases

(2020) Andreas Daiber et al.   Redox Biology

The Double-Faced Role of Nitric Oxide and Reactive Oxygen Species in Solid Tumors

(2020) Sanja Mijatović et al.   Antioxidants

Implications of HIF-1α in the tumorigenesis and progression of pancreatic cancer

(2020) Xiao Jin et al.   Cancer Cell International

Arginase as a Potential Biomarker of Disease Progression: A Molecular Imaging Perspective

(2020) Gonçalo S. Clemente et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nitrosative Stress and Its Association with Cardiometabolic Disorders

(2020) Israel Pérez-Torres et al.   MOLECULES

Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

(2020) Mariluz Soula et al.   Nature Chemical Biology

Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma

(2020) Kang An et al.   ONCOLOGY REPORTS

Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer

(2020) Raúl González et al.   Redox Biology

Nitric oxide in cellular adaptation and disease

(2020) Benjamin N. Gantner et al.   Redox Biology

The overexpression of AUF1 in colorectal cancer predicts a poor prognosis and promotes cancer progression by activating ERK and AKT pathways

(2020) Xin‐Yuan Tian et al.   Cancer Medicine

Immune-Boosting, Antioxidant and Anti-inflammatory Food Supplements Targeting Pathogenesis of COVID-19

(2020) M. Mrityunjaya et al.   Frontiers in Immunology

L-Arginine/Nitric Oxide Pathway Is Altered in Colorectal Cancer and Can Be Modulated by Novel Derivatives from Oxicam Class of Non-Steroidal Anti-Inflammatory Drugs

(2020) Małgorzata Krzystek-Korpacka et al.   Cancers

Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment

(2020) Xiang Zheng et al.   European Respiratory Review

Metabolic programming of tumor associated macrophages in the context of cancer treatment

(2020) Thomas Crezee et al.   Annals of Translational Medicine

ACP-5862 suppresses esophageal squamous cell carcinoma growth through inducing apoptosis via activation of endoplasmic reticulum stress and ROS production

(2020) Qiong Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tumor-Associated Macrophages in Tumor Immunity

(2020) Yueyun Pan et al.   Frontiers in Immunology

High-Fat Diet Promotes Macrophage-Mediated Hepatic Inflammation and Aggravates Diethylnitrosamine-Induced Hepatocarcinogenesis in Mice

(2020) Huiying Fu et al.   Frontiers in Nutrition

Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease

(2019) Holly F. Hope et al.   PLoS One

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

(2019) Laura D. Gamble et al.   Science Translational Medicine

Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment

(2019) Luke Bu et al.   ONCOGENE

Lopinavir-NO, a nitric oxide-releasing HIV protease inhibitor, suppresses the growth of melanoma cells in vitro and in vivo

(2019) Svetlana Paskas et al.   INVESTIGATIONAL NEW DRUGS

Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer

(2019) Yanfeng Gao et al.   FREE RADICAL RESEARCH

Regulators and mechanisms of anoikis in triple-negative breast cancer (TNBC): a review

(2019) Amir Tajbakhsh et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The Potential Role of iNOS in Ovarian Cancer Progression and Chemoresistance

(2019) Kielbik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prognostic and clinicopathological value of PD-L1 expression in primary breast cancer: a meta-analysis

(2019) Wenfa Huang et al.   BREAST CANCER RESEARCH AND TREATMENT

Macrophages and Metabolism in the Tumor Microenvironment

(2019) Ilio Vitale et al.   Cell Metabolism

PD-1/PD-L1 Targeting in Breast Cancer: The First Clinical Evidences Are Emerging. A Literature Review

(2019) Planes-Laine et al.   Cancers

ANGPT2 and NOS3 Polymorphisms and Clinical Outcome in Advanced Hepatocellular Carcinoma Patients Receiving Sorafenib

(2019) Giorgia Marisi et al.   Cancers

Nitric oxide and interactions with reactive oxygen species in the development of melanoma, breast, and colon cancer: A redox signaling perspective

(2019) Hugo P. Monteiro et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Systems Biology of Cancer Metastasis

(2019) Yasir Suhail et al.   Cell Systems

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition

(2019) Jared M. Newton et al.   Journal for ImmunoTherapy of Cancer

Arginine metabolism and deprivation in cancer therapy

(2019) Songyun Zou et al.   BIOMEDICINE & PHARMACOTHERAPY

Cancer and ER stress: Mutual crosstalk between autophagy, oxidative stress and inflammatory response

(2019) Yuning Lin et al.   BIOMEDICINE & PHARMACOTHERAPY

iNOS as a metabolic enzyme under stress conditions

(2019) Sarit Anavi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Imbalance between nitric oxide and superoxide anion induced by uncoupled nitric oxide synthase contributes to human melanoma development

(2019) Diego Assis Gonçalves et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

(2019) Qin Zhao et al.   MOLECULAR CELL

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling

(2019) Vanessa A. N. Kraft et al.   ACS Central Science

Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism

(2018) Veena Somasundaram et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Nitrosylation of Ras Mediates Nitric Oxide-Dependent Post-Injury Neurogenesis in a Seizure Model

(2018) Ana Isabel Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

CCR6 promotes tumor angiogenesis via the AKT/NF-κB/VEGF pathway in colorectal cancer

(2018) Cong-cong Zhu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Triple negative breast cancer: Key role of Tumor-Associated Macrophages in regulating the activity of anti-PD-1/PD-L1 agents

(2018) Matteo Santoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer

(2018) Jon Peñarando et al.   BMC BIOLOGY

Global burden of cutaneous melanoma attributable to ultraviolet radiation in 2012

(2018) Melina Arnold et al.   INTERNATIONAL JOURNAL OF CANCER

Reactive oxygen species and colorectal cancer

(2018) Sisi Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular Normalization

(2018) Christopher S. Rabender et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors

(2018) Wagner Ricardo Montor et al.   Molecular Cancer

Reactive species balance via GTP cyclohydrolase I regulates glioblastoma growth and tumor initiating cell maintenance

(2018) Anh Nhat Tran et al.   NEURO-ONCOLOGY

Nitric Oxide Signaling in T Cell-Mediated Immunity

(2018) Almudena García-Ortiz et al.   TRENDS IN MOLECULAR MEDICINE

Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration

(2018) Silvina Bartesaghi et al.   Redox Biology

Augmentation of Fluvastatin Cytotoxicity Against Prostate Carcinoma PC3 Cell Line Utilizing Alpha Lipoic–Ellagic Acid Nanostructured Lipid Carrier Formula

(2018) Usama A. Fahmy   AAPS PHARMSCITECH

Nitric oxide synthase enzymology in the 20 years after the Nobel Prize

(2018) Dennis J Stuehr et al.   BRITISH JOURNAL OF PHARMACOLOGY

Obesity and cancer risk: Emerging biological mechanisms and perspectives

(2018) Konstantinos I. Avgerinos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

(2018) Shane J. F. Cronin et al.   NATURE

Safety and efficacy of statin therapy

(2018) Bhavin B. Adhyaru et al.   Nature Reviews Cardiology

ER stress promotes antitumor effects in BRAFi/MEKi resistant human melanoma induced by natural compound 4-nerolidylcathecol (4-NC)

(2018) Débora Kristina Alves-Fernandes et al.   PHARMACOLOGICAL RESEARCH

The Nrf2/GCH1/BH4 Axis Ameliorates Radiation-Induced Skin Injury by Modulating the ROS Cascade

(2017) Jiao Xue et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The contribution of tumor-associated macrophages in glioma neo-angiogenesis and implications for anti-angiogenic strategies

(2017) Changbin Zhu et al.   NEURO-ONCOLOGY

Nitric oxide synthase and structure-based inhibitor design

(2017) Thomas L. Poulos et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

NOS2 expression in glioma cell lines and glioma primary cell cultures: correlation with neurosphere generation and SOX-2 expression

(2017) Paola Palumbo et al.   Oncotarget

Impact of inducible nitric oxide synthase (iNOS) expression on triple negative breast cancer outcome and activation of EGFR and ERK signaling pathways

(2017) Pablo Garrido et al.   Oncotarget

Obesity and cancer: inflammation bridges the two

(2016) Ryan Kolb et al.   CURRENT OPINION IN PHARMACOLOGY

Upregulation of AUF1 is involved in the proliferation of esophageal squamous cell carcinoma through GCH1

(2016) Yi Gao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways

(2016) Yue Gao et al.   JOURNAL OF PINEAL RESEARCH

Downregulation of tetrahydrobiopterin inhibits tumor angiogenesis in BALB/c-nu mice with hepatocellular carcinoma

(2016) Youguo Dai et al.   ONCOLOGY REPORTS

Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth

(2016) Liye Chen et al.   Oncotarget

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells

(2016) Clarissa Ribeiro Reily Rocha et al.   Oncotarget

Oral Concentrated Grape Juice Suppresses Expression of NF-kappa B, TNF-α and iNOS in Experimentally Induced Colorectal Carcinogenesis in Wistar Rats

(2015) Vanessa Maria de Lima Pazine Campanholo et al.   Asian Pacific Journal of Cancer Prevention

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody

(2015) Byungtae Hwang et al.   BIOMATERIALS

Cancer cell metabolism and the modulating effects of nitric oxide

(2015) Ching-Fang Chang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Global burden of cancer attributable to high body-mass index in 2012: a population-based study

(2015) Melina Arnold et al.   LANCET ONCOLOGY

The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression

(2015) C. S. Rabender et al.   MOLECULAR CANCER RESEARCH

Antimetastatic effect of fluvastatin on breast and hepatocellular carcinoma cells in relation to SGK1 and NDRG1 genes

(2015) Osman Salis et al.   TUMOR BIOLOGY

Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma

(2015) E Singer et al.   Cell Death & Disease

The dual role of iNOS in cancer

(2015) Federica Vannini et al.   Redox Biology

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon

(2015) Cristina Branco-Price et al.   Oncotarget

Polyamines metabolism and breast cancer: state of the art and perspectives

(2014) Manuela Cervelli et al.   BREAST CANCER RESEARCH AND TREATMENT

Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

(2014) S. Muenst et al.   BREAST CANCER RESEARCH AND TREATMENT

Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms

(2014) Anantha Koteswararao Kanugula et al.   FEBS Journal

Melanocytes as Instigators and Victims of Oxidative Stress

(2014) Laurence Denat et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Recent developments in the effects of nitric oxide-donating statins on cardiovascular disease through regulation of tetrahydrobiopterin and nitric oxide

(2014) Sze Ma et al.   VASCULAR PHARMACOLOGY

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

(2013) Nadine Jetten et al.   ANGIOGENESIS

Tetrahydrobiopterin: biochemistry and pathophysiology

(2013) Ernst R. Werner et al.   BIOCHEMICAL JOURNAL

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

Novel Interaction of Ornithine Decarboxylase with Sepiapterin Reductase Regulates Neuroblastoma Cell Proliferation

(2013) Ingo Lange et al.   JOURNAL OF MOLECULAR BIOLOGY

The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans

(2012) Einat Gochman et al.   ACTA HISTOCHEMICA

S-Nitrosoglutathione and Endothelial Nitric Oxide Synthase-Derived Nitric Oxide Regulate Compartmentalized Ras S-Nitrosylation and Stimulate Cell Proliferation

(2012) Wagner L. Batista et al.   ANTIOXIDANTS & REDOX SIGNALING

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

(2012) Claudia Capparelli et al.   CELL CYCLE

Tetrahydrobiopterin: A Vascular Redox Target to Improve Endothelial Function

(2012) Keith M. Channon   Current Vascular Pharmacology

Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages

(2012) Geethanjali Pickert et al.   INTERNATIONAL JOURNAL OF CANCER

Interaction between nitric oxide signaling and gap junctions: Effects on vascular function

(2011) R.C. Looft-Wilson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Rapid, Direct Effects of Statin Treatment on Arterial Redox State and Nitric Oxide Bioavailability in Human Atherosclerosis via Tetrahydrobiopterin-Mediated Endothelial Nitric Oxide Synthase Coupling

(2011) Charalambos Antoniades et al.   CIRCULATION

Endothelial nitric oxide synthase uncoupling as a key mediator of melanocyte malignant transformation associated with sustained stress conditions

(2011) Fabiana H.M. Melo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1

(2011) Beth et al.   Frontiers in Bioscience-Landmark

Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease

(2011) Mark J. Crabtree et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression

(2011) Shin Choi   ONCOLOGY REPORTS

Roles of Tetrahydrobiopterin in Promoting Tumor Angiogenesis

(2010) Liye Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

NADPH oxidase 4 mediates reactive oxygen species induction of CD146 dimerization in VEGF signal transduction

(2010) Jie Zhuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fluvastatin upregulates endothelial nitric oxide synthase activity via enhancement of its phosphorylation and expression and via an increase in tetrahydrobiopterin in vascular endothelial cells

(2010) Chie Aoki et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Tetrahydrobiopterin, superoxide, and vascular dysfunction

(2009) Jeannette Vásquez-Vivar   FREE RADICAL BIOLOGY AND MEDICINE

GTP Cyclohydrolase I Expression, Protein, and Activity Determine Intracellular Tetrahydrobiopterin Levels, Independent of GTP Cyclohydrolase Feedback Regulatory Protein Expression

(2009) Amy L. Tatham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tetrahydrobiopterin Recycling, a Key Determinant of Endothelial Nitric-oxide Synthase-dependent Signaling Pathways in Cultured Vascular Endothelial Cells

(2009) Toru Sugiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol and Piceatannol Inhibit iNOS Expression and NF-κ B Activation in Dextran Sulfate Sodium-Induced Mouse Colitis

(2009) Jin Youn et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH4-independent manner

(2008) K IKEMOTO et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Nitric oxide activated by p38 and NF-κB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells

(2008) Jia Yang et al.   FREE RADICAL RESEARCH

Guanosine Triphosphate Cyclohydrolase I Expression and Enzymatic Activity Are Present in Caveolae of Endothelial Cells

(2008) Timothy E. Peterson et al.   HYPERTENSION

Nitric oxide donor up-regulation of SDF1/CXCR4 and Ang1/Tie2 promotes neuroblast cell migration after stroke

(2008) Xu Cui et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid–nitric oxide (GIT-27NO) induces p53 mediated apoptosis in human A375 melanoma cells

(2008) Sanja Mijatovic et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells

(2007) Shunichi Shimizu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY