NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology

Nox3-derived superoxide in cochleae induces sensorineural hearing loss Mechanisms of Nox3-dependent hearing loss

(2021) Hiroaki Mohri et al.   JOURNAL OF NEUROSCIENCE

The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle

(2020) Sukyeong Heo et al.   Antioxidants

Hydrogen peroxide reactivity and specificity in thiol-based cell signalling

(2020) Christine C. Winterbourn   BIOCHEMICAL SOCIETY TRANSACTIONS

Interdomain Flexibility within NADPH Oxidase Suggested by SANS Using LMNG Stealth Carrier

(2020) Annelise Vermot et al.   BIOPHYSICAL JOURNAL

The protein kinase A negatively regulates reactive oxygen species production by phosphorylating gp91phox/NOX2 in human neutrophils

(2020) Houssam Raad et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structures of mouse DUOX1–DUOXA1 provide mechanistic insights into enzyme activation and regulation

(2020) Ji Sun   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Size matters: Ryanodine receptor cluster size heterogeneity potentiates calcium waves

(2019) Y. Xie et al.   BIOPHYSICAL JOURNAL

Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase

(2019) Cornelia S Ziegler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-talk between receptor tyrosine kinases AXL and ERBB3 regulates invadopodia formation in melanoma cells

(2019) Or-Yam Revach et al.   CANCER RESEARCH

Pharmacological characterization of the seven human NOX isoforms and their inhibitors

(2019) Fiona Augsburger et al.   Redox Biology

NOX4 is the main NADPH oxidase involved in the early stages of hematopoietic differentiation from human induced pluripotent stem cells

(2019) Julie Brault et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets

(2019) Yixuan Zhang et al.   Nature Reviews Cardiology

The Prolyl Isomerase Pin1 Controls Lipopolysaccharide-Induced Priming of NADPH Oxidase in Human Neutrophils

(2019) Min Liu et al.   Frontiers in Immunology

Structure and mechanisms of ROS generation by NADPH oxidases

(2019) Francesca Magnani et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Differential cell surface recruitment of the superoxide-producing NADPH oxidases Nox1, Nox2 and Nox5: The role of the small GTPase Sar1

(2018) Takuya Kiyohara et al.   GENES TO CELLS

Damage to dopaminergic neurons by oxidative stress in Parkinson's disease (Review)

(2018) Ji‑Dong Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Gene expression and prognosis of NOX family members in gastric cancer

(2018) Xin You et al.   OncoTargets and Therapy

Inhibition of NADPH oxidase 2 induces apoptosis in osteosarcoma: The role of reactive oxygen species in cell proliferation

(2018) Kazumasa Kitamoto et al.   Oncology Letters

Redox Signaling by Reactive Electrophiles and Oxidants

(2018) Saba Parvez et al.   CHEMICAL REVIEWS

The Many Faces of Rap1 GTPase

(2018) Anna Jaśkiewicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic Potential and Anti-Amyloidosis Mechanisms of Tert-Butylhydroquinone for Alzheimer's Disease

(2018) Hasina Akhter et al.   JOURNAL OF ALZHEIMERS DISEASE

Physiological Stimuli Induce PAD4-Dependent, ROS-Independent NETosis, With Early and Late Events Controlled by Discrete Signaling Pathways

(2018) Olga Tatsiy et al.   Frontiers in Immunology

Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus

(2018) Basel H. Abuaita et al.   Cell Host & Microbe

Engineering stability in NADPH oxidases: A common strategy for enzyme production

(2018) Marta Ceccon et al.   MOLECULAR MEMBRANE BIOLOGY

Down-regulation of NOX2 activity in phagocytes mediated by ATM-kinase dependent phosphorylation

(2017) Sylvain Beaumel et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH Oxidase-Related Pathophysiology in Experimental Models of Stroke

(2017) Hiroshi Yao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NADPH oxidases in Parkinson’s disease: a systematic review

(2017) Karim Belarbi et al.   Molecular Neurodegeneration

NADPH Oxidases: Insights into Selected Functions and Mechanisms of Action in Cancer and Stem Cells

(2017) Magdalena Skonieczna et al.   Oxidative Medicine and Cellular Longevity

Crystal structures and atomic model of NADPH oxidase

(2017) Francesca Magnani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NOX Family of Proteins Is Also Present in Bacteria

(2017) Christine Hajjar et al.   mBio

Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

(2017) Giang T. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Redox signaling during hypoxia in mammalian cells

(2017) Kimberly A. Smith et al.   Redox Biology

Exploring the arachidonic acid-induced structural changes in phagocyte NADPH oxidase p47phoxand p67phoxvia thiol accessibility and SRCD spectroscopy

(2016) Tania Bizouarn et al.   FEBS Journal

The intimate and controversial relationship between voltage-gated proton channels and the phagocyte NADPH oxidase

(2016) Thomas E. DeCoursey   IMMUNOLOGICAL REVIEWS

A Two-component NADPH Oxidase (NOX)-like System in Bacteria Is Involved in the Electron Transfer Chain to the Methionine Sulfoxide Reductase MsrP

(2016) Céline Juillan-Binard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B

(2016) Jessica M. Wilson et al.   JOURNAL OF MOLECULAR BIOLOGY

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

(2016) Kim-Kristin Prior et al.   Redox Biology

BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX Pathway

(2016) Suhrid Banskota et al.   PLoS One

The Impact of Myeloperoxidase and Activated Macrophages on Metaphase II Mouse Oocyte Quality

(2016) Faten Shaeib et al.   PLoS One

The NADPH Oxidase Nox4 mediates tumour angiogenesis

(2015) V. Helfinger et al.   Acta Physiologica

Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques

(2015) I.M. Quesada et al.   ATHEROSCLEROSIS

NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1 /G-CSF axis

(2015) J. Bagaitkar et al.   BLOOD

NOX3-TARGETED THERAPIES FOR INNER EAR PATHOLOGIES

(2015) Francis Rousset et al.   CURRENT PHARMACEUTICAL DESIGN

Lipopolysaccharide (LPS)-mediated Angiopoietin-2-dependent Autocrine Angiogenesis Is Regulated by NADPH Oxidase 2 (Nox2) in Human Pulmonary Microvascular Endothelial Cells

(2015) Heather Menden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Extracellular A-loop of Dual Oxidases Affects the Specificity of Reactive Oxygen Species Release

(2015) Takehiko Ueyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN

(2015) S. V. R. Kumar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons

(2015) Alexandra Gennaris et al.   NATURE

NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer

(2015) Xiyu Liu et al.   TUMOR BIOLOGY

Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancer

(2015) Peng Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia-Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide-Dependent Mechanisms

(2015) B. A. Di Bartolo et al.   Journal of the American Heart Association

Genetic disorders coupled to ROS deficiency

(2015) Sharon O’Neill et al.   Redox Biology

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

NADPH Oxidase–Generated Reactive Oxygen Species Are Required for Stromal Cell–Derived Factor-1α–Stimulated Angiogenesis

(2014) Xinchun Pi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

(2014) Yukio Nisimoto et al.   BIOCHEMISTRY

Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis in endothelial Nox4 transgenic mouse lines

(2014) Lili Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells

(2014) H E Boudreau et al.   BRITISH JOURNAL OF CANCER

Phosphorylation of Nox1 Regulates Association With NoxA1 Activation Domain

(2014) Jennifer Streeter et al.   CIRCULATION RESEARCH

NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

(2014) Marc Röhm et al.   INFECTION AND IMMUNITY

Transforming growth factor-β1 requires NADPH oxidase 4 for angiogenesisin vitroandin vivo

(2014) Hitesh M Peshavariya et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MMP9 activation triggered by epidermal growth factor induced FoxO1 nuclear exclusion in non-small cell lung cancer

(2014) Jun Pei et al.   TUMOR BIOLOGY

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

(2014) Hon S. Leong et al.   Cell Reports

Nox Enzymes and New Thinking on Reactive Oxygen: A Double-Edged Sword Revisited

(2013) J. David Lambeth et al.   Annual Review of Pathology-Mechanisms of Disease

NADPH Oxidase 1, a Novel Molecular Source of ROS in Hippocampal Neuronal Death in Vascular Dementia

(2013) Dong-Hee Choi et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH Oxidases in Vascular Pathology

(2013) Anna Konior et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH Oxidases: A Perspective on Reactive Oxygen Species Production in Tumor Biology

(2013) Jennifer L. Meitzler et al.   ANTIOXIDANTS & REDOX SIGNALING

Toll-Like Receptor 4 Mutation Protects Obese Mice Against Endothelial Dysfunction by Decreasing NADPH Oxidase Isoforms 1 and 4

(2013) Chao-Fan Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

N-linked glycosylation of the superoxide-producing NADPH oxidase Nox1

(2013) Kei Miyano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High glucose condition increases NADPH oxidase activity in endothelial microparticles that promote vascular inflammation

(2013) Felix Jansen et al.   CARDIOVASCULAR RESEARCH

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

(2013) Stephen P. Gray et al.   CIRCULATION

An Extracellular Matrix-Based Mechanism of Rapid Neutrophil Extracellular Trap Formation in Response to Candida albicans

(2013) A. S. Byrd et al.   JOURNAL OF IMMUNOLOGY

Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury

(2013) Sean J Cooney et al.   Journal of Neuroinflammation

CXCR4, but not CXCR7, Discriminates Metastatic Behavior in Non–Small Cell Lung Cancer Cells

(2013) Young H. Choi et al.   MOLECULAR CANCER RESEARCH

Invading one step at a time: the role of invadopodia in tumor metastasis

(2013) H Paz et al.   ONCOGENE

NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice

(2013) Marina S. Hernandes et al.   Oxidative Medicine and Cellular Longevity

ROS and Brain Diseases: The Good, the Bad, and the Ugly

(2013) Aurel Popa-Wagner et al.   Oxidative Medicine and Cellular Longevity

Evolution of the Ferric Reductase Domain (FRD) Superfamily: Modularity, Functional Diversification, and Signature Motifs

(2013) Xuezhi Zhang et al.   PLoS One

Non-Essential Role for TLR2 and Its Signaling Adaptor Mal/TIRAP in Preserving Normal Lung Architecture in Mice

(2013) Saleela M. Ruwanpura et al.   PLoS One

Regulation Of The NADPH Oxidase And Associated Ion Fluxes During Phagocytosis

(2013) Paula Nunes et al.   TRAFFIC

Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

(2013) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

Reactive oxidants and myeloperoxidase and their involvement in neutrophil extracellular traps

(2013) Heather Parker et al.   Frontiers in Immunology

Endocytosis of soluble immune complexes leads to their clearance by Fc RIIIB but induces neutrophil extracellular traps via Fc RIIA in vivo

(2012) K. Chen et al.   BLOOD

Autophagy Protein Rubicon Mediates Phagocytic NADPH Oxidase Activation in Response to Microbial Infection or TLR Stimulation

(2012) Chul-Su Yang et al.   Cell Host & Microbe

siRNA-mediated knock-down of NOX3: therapy for hearing loss?

(2012) Leonard P. Rybak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Characterization of the 1st and 2nd EF-hands of NADPH oxidase 5 by fluorescence, isothermal titration calorimetry, and circular dichroism

(2012) Chin-Chuan Wei et al.   Chemistry Central Journal

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Consensus in silico computational modelling of the p22phox subunit of the NADPH oxidase

(2012) Daniel N. Meijles et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

NADPH Oxidase and Neurodegeneration

(2012) Marina S. Hernandes et al.   Current Neuropharmacology

Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration

(2012) Alicia M. Evangelista et al.   FREE RADICAL BIOLOGY AND MEDICINE

TG-interacting factor-induced superoxide production from NADPH oxidase contributes to the migration/invasion of urothelial carcinoma

(2012) Huei-Sheng Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

(2012) S. J. Klebanoff et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mice Deficient in Dual Oxidase Maturation Factors Are Severely Hypothyroid

(2012) Helmut Grasberger et al.   MOLECULAR ENDOCRINOLOGY

TLR-4 Signalling Accelerates Colon Cancer Cell Adhesion via NF-κB Mediated Transcriptional Up-Regulation of Nox-1

(2012) D. Peter O'Leary et al.   PLoS One

Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime

(2011) Paola Gamba et al.   AGING CELL

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

(2011) Robin Ray et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox5 Forms a Functional Oligomer Mediated by Self-Association of Its Dehydrogenase Domain

(2011) Tsukasa Kawahara et al.   BIOCHEMISTRY

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

(2011) Siobhan M. Craige et al.   CIRCULATION

Redox signaling in cardiac myocytes

(2011) Celio X.C. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Control of Hepatic Nuclear Superoxide Production by Glucose 6-Phosphate Dehydrogenase and NADPH Oxidase-4

(2011) Netanya Y. Spencer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ethyl Pyruvate Rescues Nigrostriatal Dopaminergic Neurons by Regulating Glial Activation in a Mouse Model of Parkinson's Disease

(2011) S. H. Huh et al.   JOURNAL OF IMMUNOLOGY

Initial steps of metastasis: Cell invasion and endothelial transmigration

(2011) Franziska van Zijl et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

Cognitive impairment in humanized APP×PS1 mice is linked to Aβ1–42 and NOX activation

(2011) Annadora J. Bruce-Keller et al.   NEUROBIOLOGY OF DISEASE

Correction: Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

(2011) Sarah Garrido-Urbani et al.   PLoS One

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

(2010) Yukio Nisimoto et al.   BIOCHEMISTRY

Chronic Granulomatous Disease: Lessons from a Rare Disorder

(2010) Brahm H. Segal et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The prolyl isomerase Pin1 acts as a novel molecular switch for TNF- -induced priming of the NADPH oxidase in human neutrophils

(2010) T. Boussetta et al.   BLOOD

Hematologically important mutations: The autosomal recessive forms of chronic granulomatous disease (second update)

(2010) Dirk Roos et al.   BLOOD CELLS MOLECULES AND DISEASES

Hematologically important mutations: X-linked chronic granulomatous disease (third update)

(2010) Dirk Roos et al.   BLOOD CELLS MOLECULES AND DISEASES

NADPH oxidase 4 is an oncoprotein localized to mitochondria

(2010) Kelly A. Graham et al.   CANCER BIOLOGY & THERAPY

Activation of store-operated ICRAC by hydrogen peroxide

(2010) Morten Grupe et al.   CELL CALCIUM

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death

(2010) Chi Fung Lee et al.   CIRCULATION RESEARCH

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals

(2010) Jesús Aguirre et al.   FREE RADICAL BIOLOGY AND MEDICINE

HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

(2010) Viktor Malec et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vascular Functions of NADPH Oxidases

(2010) Ralf P. Brandes   HYPERTENSION

Regulation of NADPH Oxidase Activity in Phagocytes

(2010) Franck Debeurme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p47phoxMolecular Activation for Assembly of the Neutrophil NADPH Oxidase Complex

(2010) Julien Marcoux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes

(2010) Assaad A. Eid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiogenic effects of stromal cell-derived factor-1 (SDF-1/CXCL12) variants in vitro and the in vivo expressions of CXCL12 variants and CXCR4 in human critical leg ischemia

(2010) Teik K. Ho et al.   JOURNAL OF VASCULAR SURGERY

The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway

(2010) A Salmeen et al.   ONCOGENE

pH regulation and beyond: unanticipated functions for the voltage-gated proton channel, HVCN1

(2010) Melania Capasso et al.   TRENDS IN CELL BIOLOGY

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

Getting Radical About Obesity

(2009) Matthias Barton et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Restoration of NET formation by gene therapy in CGD controls aspergillosis

(2009) M. Bianchi et al.   BLOOD

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

(2009) Alicia N. Lyle et al.   CIRCULATION RESEARCH

Targeting the Progression of Parkinsons Disease

(2009) J. George et al.   Current Neuropharmacology

Conformational changes in p47phoxupon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis

(2009) Julien Marcoux et al.   FEBS LETTERS

Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues

(2009) Agnes Juhasz et al.   FREE RADICAL RESEARCH

Caenorhabditis elegansand Human Dual Oxidase 1 (DUOX1) “Peroxidase” Domains

(2009) Jennifer L. Meitzler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells

(2009) Hetian Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOX4 Expression in Human Microglia Leads to Constitutive Generation of Reactive Oxygen Species and to Constitutive IL-6 Expression

(2009) Bin Li et al.   Journal of Innate Immunity

NADPH oxidase activator p67phox behaves in solution as a multidomain protein with semi-flexible linkers

(2009) Dominique Durand et al.   JOURNAL OF STRUCTURAL BIOLOGY

Chronic Granulomatous Disease: The European Experience

(2009) J. Merlijn van den Berg et al.   PLoS One

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

(2009) I. S. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

(2009) D. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel p47phox-Related Organizers Regulate Localized NADPH Oxidase 1 (Nox1) Activity

(2009) D. Gianni et al.   Science Signaling

Tks5-Dependent, Nox-Mediated Generation of Reactive Oxygen Species Is Necessary for Invadopodia Formation

(2009) B. Diaz et al.   Science Signaling

Renal mitochondrial damage and protein modification in type-2 diabetes

(2008) Ganesh K. Kartha et al.   ACTA DIABETOLOGICA

Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells

(2008) Srikanth Pendyala et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

(2008) Katrin Schröder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

(2008) Seung-Nam Jung et al.   CARCINOGENESIS

STIM, ORAI AND TRPC CHANNELS IN THE CONTROL OF CALCIUM ENTRY SIGNALS IN SMOOTH MUSCLE

(2008) Youjun Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species

(2008) Hideki Sumimoto   FEBS Journal

Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras

(2008) Eunice Laurent et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

(2008) C. Cheret et al.   JOURNAL OF NEUROSCIENCE

Role of protein kinase Cδ in paraquat‐induced glial cell death

(2008) Sangseop Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS

(2008) J. Rodriguez-Pallares et al.   NEUROBIOLOGY OF DISEASE

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

(2008) L. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

La granulomatose septique chronique

(2008) M.J. Stasia et al.   REVUE DE MEDECINE INTERNE

Genetics and immunopathology of chronic granulomatous disease

(2008) Marie José Stasia et al.   Seminars in Immunopathology

STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells

(2007) Jin Si et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The function of the NADPH oxidase of phagocytes and its relationship to other NOXs in plants, invertebrates, and mammals

(2007) Anthony W. Segal   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY