Polyamines metabolism and breast cancer: state of the art and perspectives

The Glu216/Ser218pocket is a major determinant of spermine oxidase substrate specificity

(2014) Manuela Cervelli et al.   BIOCHEMICAL JOURNAL

Inflammation, carcinogenesis and neurodegeneration studies in transgenic animal models for polyamine research

(2013) Manuela Cervelli et al.   AMINO ACIDS

Spermine metabolism and radiation-derived reactive oxygen species for future therapeutic implications in cancer: an additive or adaptive response

(2013) Roberto Amendola et al.   AMINO ACIDS

Increased breast cancer cell toxicity by palladination of the polyamine analogue N 1,N 11-bis(ethyl)norspermine

(2013) Tania M. Silva et al.   AMINO ACIDS

High-Throughput LC–MS/MS Based Simultaneous Determination of Polyamines Including N-Acetylated Forms in Human Saliva and the Diagnostic Approach to Breast Cancer Patients

(2013) Haruhito Tsutsui et al.   ANALYTICAL CHEMISTRY

Polyamines and cancer: implications for chemotherapy and chemoprevention

(2013) Shannon L. Nowotarski et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity

(2013) Caterina Capone et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structure–Function Relationships in the Evolutionary Framework of Spermine Oxidase

(2013) Manuela Cervelli et al.   JOURNAL OF MOLECULAR EVOLUTION

Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells

(2013) Pınar Obakan et al.   MOLECULAR BIOLOGY REPORTS

Norspermidine and Novel Pd(II) and Pt(II) Polynuclear Complexes of Norspermidine as Potential Antineoplastic Agents Against Breast Cancer

(2013) Tânia Magalhães Silva et al.   PLoS One

A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury

(2013) Manuela Cervelli et al.   PLoS One

Molecular evolution of the polyamine oxidase gene family in Metazoa

(2012) Fabio Polticelli et al.   BMC EVOLUTIONARY BIOLOGY

Role of ornithine decarboxylase in regulation of estrogen receptor alpha expression and growth in human breast cancer cells

(2012) Qingsong Zhu et al.   BREAST CANCER RESEARCH AND TREATMENT

Synthesis of Bisethylnorspermine Lipid Prodrug as Gene Delivery Vector Targeting Polyamine Metabolism in Breast Cancer

(2012) Yanmei Dong et al.   MOLECULAR PHARMACEUTICS

Arginase Activity in Patients with Breast Cancer: An Analysis of Plasma, Tumors, and Its Relationship with the Presence of the Estrogen Receptor

(2012) Gabriel Perez et al.   ONKOLOGIE

Spermine oxidase: ten years after

(2011) Manuela Cervelli et al.   AMINO ACIDS

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

(2011) Qingsong Zhu et al.   AMINO ACIDS

Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes

(2011) Yu Wu et al.   BIOCHEMICAL JOURNAL

Novel Pt(II) and Pd(II) complexes with polyamine analogues: Synthesis and vibrational analysis

(2011) T.M. Silva et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

(2011) A. C. Goodwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing mammalian spermine oxidase enzyme–substrate complex through molecular modeling, site-directed mutagenesis and biochemical characterization

(2010) Paraskevi Tavladoraki et al.   AMINO ACIDS

Reduction of the putative CD44+CD24− breast cancer stem cell population by targeting the polyamine metabolic pathway with PG11047

(2010) Helena Cirenajwis et al.   ANTI-CANCER DRUGS

Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm

(2010) Manuela Cervelli et al.   BMC CANCER

Polyamine catabolism and disease

(2009) Robert A. Casero et al.   BIOCHEMICAL JOURNAL

The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines

(2009) Allison Pledgie-Tracy et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Spermine Metabolism and Anticancer Therapy

(2009) R. Amendola et al.   CURRENT CANCER DRUG TARGETS

Mammalian polyamine metabolism and function

(2009) Anthony E. Pegg   IUBMB LIFE

Recent Advances in the Development of Polyamine Analogues as Antitumor Agents§

(2009) Robert A. Casero et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analytical methodologies for metallomics studies of antitumor Pt-containing drugs

(2009) Diego Esteban-Fernández et al.   Metallomics

Breast Cancer Stem Cells and Intrinsic Subtypes: Controversies Rage On

(2009) Harikrishna Nakshatri et al.   Current Stem Cell Research & Therapy

In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells

(2008) Amy Hacker et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Effect of Difluoromethylornithine on Decreasing Prostate Size and Polyamines in Men: Results of a Year-Long Phase IIb Randomized Placebo-Controlled Chemoprevention Trial

(2008) A. R. Simoneau et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Difluoromethylornithine Plus Sulindac for the Prevention of Sporadic Colorectal Adenomas: A Randomized Placebo-Controlled, Double-Blind Trial

(2008) Frank L. Meyskens et al.   Cancer Prevention Research

The Novel Polyamine Analogue CGC-11093 Enhances the Antimyeloma Activity of Bortezomib

(2008) J. S. Carew et al.   CANCER RESEARCH

Polyaminohydroxamic Acids and Polyaminobenzamides as Isoform Selective Histone Deacetylase Inhibitors§

(2008) Sheeba Varghese et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel anti-apoptotic effect of Bcl-2: Prevention of polyamine depletion-induced cell death

(2007) C HOLST et al.   CELL BIOLOGY INTERNATIONAL