Stress tolerance enhancement via SPT15 base editing in Saccharomyces cerevisiae

Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors

(2020) Chao Li et al.   NATURE BIOTECHNOLOGY

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

(2020) Xiaohui Zhang et al.   NATURE BIOTECHNOLOGY

Perturbing proteomes at single residue resolution using base editing

(2020) Philippe C. Després et al.   Nature Communications

Microbial Base Editing: A Powerful Emerging Technology for Microbial Genome Engineering

(2020) Yu Wang et al.   TRENDS IN BIOTECHNOLOGY

CRISPR-Assisted Multiplex Base Editing System in Pseudomonas putida KT2440

(2020) Jun Sun et al.   Frontiers in Bioengineering and Biotechnology

Yeast Systems Biology: Model organism and Cell Factory

(2019) Jens Nielsen   Biotechnology Journal

Complex modifier landscape underlying genetic background effects

(2019) Jing Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

QTL analysis reveals genomic variants linked to high-temperature fermentation performance in the industrial yeast

(2019) Zhen Wang et al.   Biotechnology for Biofuels

Domestication of Industrial Microbes

(2019) Jan Steensels et al.   CURRENT BIOLOGY

A CRISPR/Cas9 method to generate heterozygous alleles in Saccharomyces cerevisiae

(2019) Steve F. EauClaire et al.   YEAST

Quantitative Trait Nucleotides Impacting the Technological Performances of Industrial Saccharomyces cerevisiae Strains

(2019) Emilien Peltier et al.   Frontiers in Genetics

Overcoming lignocellulose‐derived microbial inhibitors: advancing the Saccharomyces cerevisiae resistance toolbox

(2019) Bianca A. Brandt et al.   Biofuels Bioproducts & Biorefining-Biofpr

Enhanced scale and scope of genome engineering and regulation using CRISPR/Cas in Saccharomyces cerevisiae

(2019) Matthew Deaner et al.   FEMS YEAST RESEARCH

Extensive impact of low-frequency variants on the phenotypic landscape at population-scale

(2019) Téo Fournier et al.   eLife

Engineering global transcription to tune lipophilic properties in Yarrowia lipolytica

(2018) Man Wang et al.   Biotechnology for Biofuels

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

(2018) Jiazhang Lian et al.   Biotechnology Journal

Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change

(2018) Richard She et al.   CELL

Diverse yeasts for diverse fermented beverages and foods

(2018) Chris Todd Hittinger et al.   CURRENT OPINION IN BIOTECHNOLOGY

MACBETH: Multiplex automated Corynebacterium glutamicum base editing method

(2018) Yu Wang et al.   METABOLIC ENGINEERING

Recent advances in metabolic engineering of Saccharomyces cerevisiae : New tools and their applications

(2018) Jiazhang Lian et al.   METABOLIC ENGINEERING

Molecular mechanisms driving transcriptional stress responses

(2018) Anniina Vihervaara et al.   NATURE REVIEWS GENETICS

Genome-wide association across Saccharomyces cerevisiae strains reveals substantial variation in underlying gene requirements for toxin tolerance

(2018) Maria Sardi et al.   PLoS Genetics

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

(2018) Jiazhang Lian et al.   Biotechnology Journal

Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus

(2018) Pengsong Li et al.   Biotechnology for Biofuels

Role of phosphate limitation and pyruvate decarboxylase in rewiring of the metabolic network for increasing flux towards isoprenoid pathway in a TATA binding protein mutant of Saccharomyces cerevisiae

(2018) Manisha Wadhwa et al.   Microbial Cell Factories

Genome evolution across 1,011 Saccharomyces cerevisiae isolates

(2018) Jackson Peter et al.   NATURE

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

(2018) Johnny H. Hu et al.   NATURE

A resource of variant effect predictions of single nucleotide variants in model organisms

(2018) Omar Wagih et al.   Molecular Systems Biology

CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

(2017) Pierre Billon et al.   MOLECULAR CELL

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

YEASTRACT: an upgraded database for the analysis of transcription regulatory networks in Saccharomyces cerevisiae

(2017) Miguel C Teixeira et al.   NUCLEIC ACIDS RESEARCH

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

(2017) Weixin Tang et al.   Nature Communications

A novel constructed SPT15 mutagenesis library of Saccharomyces cerevisiae by using gTME technique for enhanced ethanol production

(2017) Ashraf A. M. M. El-Rotail et al.   AMB Express

Cross-stress resistance in Saccharomyces cerevisiae yeast—new insight into an old phenomenon

(2016) Agata Święciło   CELL STRESS & CHAPERONES

Reprogramming of nonfermentative metabolism by stress-responsive transcription factors in the yeast Saccharomyces cerevisiae

(2016) Nitnipa Soontorngun   CURRENT GENETICS

CRISPR/Cas9 advances engineering of microbial cell factories

(2016) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

Transcription initiation complex structures elucidate DNA opening

(2016) C. Plaschka et al.   NATURE

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells

(2016) Yunqing Ma et al.   NATURE METHODS

Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems

(2016) K. Nishida et al.   SCIENCE

Seamless site-directed mutagenesis of the Saccharomyces cerevisiae genome using CRISPR-Cas9

(2016) Damien Biot-Pelletier et al.   Journal of Biological Engineering

TALENs-Assisted Multiplex Editing for Accelerated Genome Evolution To Improve Yeast Phenotypes

(2015) Guoqiang Zhang et al.   ACS Synthetic Biology

Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1

(2015) Agata Butryn et al.   eLife

Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas

(2015) Andrew A. Horwitz et al.   Cell Systems

Tolerance to acetic acid is improved by mutations of the TATA-binding protein gene

(2014) Jieun An et al.   ENVIRONMENTAL MICROBIOLOGY

Improvement of oxidative stress tolerance in Saccharomyces cerevisiae through global transcription machinery engineering

(2014) Hongwei Zhao et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Mutations on the DNA Binding Surface of TBP Discriminate between Yeast TATA and TATA-Less Gene Transcription

(2014) I. Kamenova et al.   MOLECULAR AND CELLULAR BIOLOGY

Selection of chromosomal DNA libraries using a multiplex CRISPR system

(2014) Owen W Ryan et al.   eLife

Mutations of the TATA-binding protein confer enhanced tolerance to hyperosmotic stress in Saccharomyces cerevisiae

(2013) Na-Rae Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation

(2013) Madhanagopal Anandapadamanaban et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Modeling regulatory cascades using Artificial Neural Networks: the case of transcriptional regulatory networks shaped during the yeast stress response

(2013) Maria E. Manioudaki et al.   Frontiers in Genetics

Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway

(2012) Allegra A. Petti et al.   MOLECULAR BIOLOGY OF THE CELL

TFRank: network-based prioritization of regulatory associations underlying transcriptional responses

(2011) Joana P. Gonçalves et al.   BIOINFORMATICS

Construction of Saccharomyces cerevisiae strains with enhanced ethanol tolerance by mutagenesis of the TATA-binding protein gene and identification of novel genes associated with ethanol tolerance

(2011) Jungwoo Yang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A systems-level approach for metabolic engineering of yeast cell factories

(2011) Il-Kwon Kim et al.   FEMS YEAST RESEARCH

Cross-talks of sensory transcription networks in response to various environmental stresses

(2009) Ting Chen et al.   Interdisciplinary Sciences-Computational Life Sciences

Cooperative action of NC2 and Mot1p to regulate TATA-binding protein function across the genome

(2008) F. J. van Werven et al.   GENES & DEVELOPMENT

[Front cover]

(2008)   IEEE SOFTWARE