CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

Title
CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons
Authors
Keywords
CRISPR-mediated base editing, STOP codons, iSTOP, RFLP assay, genome-wide sgRNA analysis, nonsense mutations, cancer
Journal
MOLECULAR CELL
Volume 67, Issue 6, Pages 1068-1079.e4
Publisher
Elsevier BV
Online
2017-09-08
DOI
10.1016/j.molcel.2017.08.008

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