Mitochondrial Oxidative Stress and “Mito-Inflammation”: Actors in the Diseases

Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence

(2020) Sevana Khaloian et al.   GUT

Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress

(2020) Liwei Hang et al.   Drug Design Development and Therapy

The role of glutathione and glutathione peroxidase in regulating cellular level of reactive oxygen and nitrogen species

(2020) Sheetal Panday et al.   MICROVASCULAR RESEARCH

Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

(2020) Alessandro Rimessi et al.   Science Advances

The Role of Mitochondria in Inflammation: From Cancer to Neurodegenerative Disorders

(2020) Sonia Missiroli et al.   Journal of Clinical Medicine

The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan

(2020) Kelvin Yen et al.   Aging-US

Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

(2020) Heiko Bugger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative Stress in Cancer

(2020) John D. Hayes et al.   CANCER CELL

Mitochondrial Stress Responses and “Mito-Inflammation” in Cystic Fibrosis

(2020) Simone Patergnani et al.   Frontiers in Pharmacology

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2019) Valery L Feigin et al.   LANCET NEUROLOGY

Crosstalk between Calcium and ROS in Pathophysiological Conditions

(2019) Simona Feno et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial DNA: the overlooked oncogenome?

(2019) Payam A. Gammage et al.   BMC BIOLOGY

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

(2019) Jiayi Zhao et al.   Scientific Reports

Metabolic remodeling induced by mitokines in heart failure

(2019) Jiahao Duan et al.   Aging-US

Relationship Between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues

(2019) Burgos-Morón et al.   Journal of Clinical Medicine

Reactive Oxygen Species in the Tumor Microenvironment: An Overview

(2019) Frank Weinberg et al.   Cancers

Mechanistic Connections between Endoplasmic Reticulum (ER) Redox Control and Mitochondrial Metabolism

(2019) Yuxiang Fan et al.   Cells

NLRP3 inflammasome activation drives tau pathology

(2019) Christina Ising et al.   NATURE

Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14

(2019) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncoupling protein 1 inhibits mitochondrial reactive oxygen species generation and alleviates acute kidney injury

(2019) Ping Jia et al.   EBioMedicine

Mitochondrial Genome (mtDNA) Mutations that Generate Reactive Oxygen Species

(2019) Hahn et al.   Antioxidants

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

Mitochondrial ROS Drive Sudden Cardiac Death and Chronic Proteome Remodeling in Heart FailureNovelty and Significance

(2018) Swati Dey et al.   CIRCULATION RESEARCH

MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload

(2018) Rogério Faustino Ribeiro Junior et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

(2018) Verónica Eisner et al.   NATURE CELL BIOLOGY

Mitochondrial function — gatekeeper of intestinal epithelial cell homeostasis

(2018) Eva Rath et al.   Nature Reviews Gastroenterology & Hepatology

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

(2018) Kate McArthur et al.   SCIENCE

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

(2018) Xianxian Wu et al.   Cell Death & Disease

Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway

(2018) Liyan Hou et al.   Redox Biology

13 reasons why the brain is susceptible to oxidative stress

(2018) James Nathan Cobley et al.   Redox Biology

The role of mitochondria in NLRP3 inflammasome activation

(2018) Qiuyun Liu et al.   MOLECULAR IMMUNOLOGY

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

(2018) Zhenyu Zhong et al.   NATURE

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles

(2018) Massimo Bonora et al.   Nature Reviews Cardiology

The machineries, regulation and cellular functions of mitochondrial calcium

(2018) Carlotta Giorgi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Mitochondrial Encoded Messenger at the Nucleus

(2018) Cheryl Yong et al.   Cells

Revisiting the Warburg Effect: Some Tumors Hold Their Breath

(2018) Sydney M. Sanderson et al.   Cell Metabolism

Inhibitors of NF-κB and P2X7/NLRP3/Caspase 1 pathway in microglia: Novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimer’s disease

(2018) Baban S. Thawkar et al.   JOURNAL OF NEUROIMMUNOLOGY

NLRP3 inflammasome: Its regulation and involvement in atherosclerosis

(2017) Zahra Hoseini et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity

(2017) Zhiwei Dong et al.   MOLECULAR CELL

Mitochondrial Complex II: At the Crossroads

(2017) Ayenachew Bezawork-Geleta et al.   TRENDS IN BIOCHEMICAL SCIENCES

The mitochondrial permeability transition pore in AD 2016: An update

(2016) Lucia Biasutto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Metabolic Heterogeneity in Human Lung Tumors

(2016) Christopher T. Hensley et al.   CELL

Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers

(2016) Xiaojing Liu et al.   Cell Metabolism

Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents AtherosclerosisNovelty and Significance

(2016) Gantsetseg Tumurkhuu et al.   CIRCULATION RESEARCH

Mitochondrial Function, Biology, and Role in Disease

(2016) Elizabeth Murphy et al.   CIRCULATION RESEARCH

The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR

(2016) Christopher J. Fiorese et al.   CURRENT BIOLOGY

Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

(2016) Rui Ni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies

(2016) Alessandro Rimessi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation

(2016) Helena Kyunghee Kim et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease

(2016) Adam Jerzy Białas et al.   Oxidative Medicine and Cellular Longevity

Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target

(2016) Maria Elena Manni et al.   Oxidative Medicine and Cellular Longevity

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

(2016) Rossana G. Iannitti et al.   Nature Communications

Mitochondrial damage contributes toPseudomonas aeruginosaactivation of the inflammasome and is downregulated by autophagy

(2015) Majid Sakhi Jabir et al.   Autophagy

Structure and function of mitochondrial membrane protein complexes

(2015) Werner Kühlbrandt   BMC BIOLOGY

Inflammation-induced ROS generation causes pancreatic cell death through modulation of Nrf2/NF-κB and SAPK/JNK pathway

(2015) S. Choudhury et al.   FREE RADICAL RESEARCH

Mitochondria in the Regulation of Innate and Adaptive Immunity

(2015) Samuel E. Weinberg et al.   IMMUNITY

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

(2015) Jing Geng et al.   NATURE IMMUNOLOGY

A mitochondrial switch between transcription and replication

(2015) Andrea Du Toit   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure

(2015) Liuji Chen et al.   NEUROBIOLOGY OF AGING

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways

(2015) Junghyung Park et al.   NEUROSCIENCE LETTERS

Inflammation and its genesis in cystic fibrosis

(2015) David P. Nichols et al.   PEDIATRIC PULMONOLOGY

Modulation of Innate Immune Signalling by Lipid-Mediated MAVS Transmembrane Domain Oligomerization

(2015) Luis Nobre et al.   PLoS One

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

(2015) Alessandro Rimessi et al.   Nature Communications

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes

(2015) Yasuo Ido et al.   PLoS One

TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

(2014) Yi Liu et al.   BASIC RESEARCH IN CARDIOLOGY

Redundant and Cooperative Interactions between TLR5 and NLRC4 in Protective Lung Mucosal Immunity against Pseudomonas aeruginosa

(2014) Leslie Tolle et al.   Journal of Innate Immunity

Monoamine oxidases as sources of oxidants in the heart

(2014) Nina Kaludercic et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

(2014) Mark W. Pellegrino et al.   NATURE

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

(2014) Asima Bhattacharyya et al.   PHYSIOLOGICAL REVIEWS

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

(2014) A. Vozza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of reactive oxygen species and metabolism on cancer cells and their microenvironment

(2014) Ana Costa et al.   SEMINARS IN CANCER BIOLOGY

The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet

(2014) Sarah J. Mitchell et al.   Cell Reports

Reactive oxygen species and redox compartmentalization

(2014) Nina Kaludercic et al.   Frontiers in Physiology

DAMP-Mediated Activation of NLRP3-Inflammasome in Brain Sterile Inflammation: The Fine Line between Healing and Neurodegeneration

(2014) Anna Rubartelli   Frontiers in Immunology

NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage

(2013) Qingyi Ma et al.   ANNALS OF NEUROLOGY

PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy

(2013) Simone Patergnani et al.   Autophagy

Structures of mitochondrial oxidative phosphorylation supercomplexes and mechanisms for their stabilisation

(2013) Yuriy Chaban et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation

(2013) Naeha Subramanian et al.   CELL

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

(2013) Xinyuan Li et al.   Journal of Hematology & Oncology

The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity

(2013) S. Park et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Dysfunction: A Basic Mechanism in Inflammation-Related Non-Communicable Diseases and Therapeutic Opportunities

(2013) Anna Hernández-Aguilera et al.   MEDIATORS OF INFLAMMATION

Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production

(2013) Mark P Brynildsen et al.   NATURE BIOTECHNOLOGY

H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling

(2013) A Rimessi et al.   ONCOGENE

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress

(2013) Y Cheng et al.   Cell Death & Disease

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

(2013) Changyoun Kim et al.   Nature Communications

COX5B Regulates MAVS-mediated Antiviral Signaling through Interaction with ATG5 and Repressing ROS Production

(2013) Yuanyuan Zhao et al.   PLoS Pathogens

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

Determinants and clinical significance of plasma oxidized LDLs in older individuals. A 9 years follow-up study

(2012) Giovanni Zuliani et al.   ATHEROSCLEROSIS

Cellular and molecular mechanisms of mitochondrial function

(2012) Laura D. Osellame et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues

(2012) Tomáš Mráček et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Modified lipoproteins provide lipids that modulate dendritic cell immune function

(2012) Laure Perrin-Cocon et al.   BIOCHIMIE

The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type

(2012) Mariia O. Yuneva et al.   Cell Metabolism

Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production

(2012) Rongxue Wu et al.   EMBO Molecular Medicine

Mitochondrial compartmentalization of redox processes

(2012) Ariel R. Cardoso et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial DNA damage Is associated with reduced mitochondrial bioenergetics in Huntington's disease

(2012) Almas Siddiqui et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Dysfunction and Oxidative Stress Promote Apoptotic Cell Death in the Striatum via Cytochrome c/ Caspase-3 Signaling Cascade Following Chronic Rotenone Intoxication in Rats

(2012) Tsu-Kung Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Free Radicals in the Aging Brain and Parkinson’s Disease: Convergence and Parallelism

(2012) Hemant Kumar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Refined Analysis of Superoxide Production by Mitochondrialsn-Glycerol 3-Phosphate Dehydrogenase

(2012) Adam L. Orr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative stress in inflammation-based gastrointestinal tract diseases: Challenges and opportunities

(2012) Yoon Jae Kim et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Mitochondria, oxidative stress and neurodegeneration

(2012) Antonio Federico et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Metabolism of [U-13C]glucose in human brain tumorsin vivo

(2012) Elizabeth A. Maher et al.   NMR IN BIOMEDICINE

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

(2011) Tiziana Anelli et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

Mitochondrial ROS fuel the inflammasome

(2011) Matthew T Sorbara et al.   CELL RESEARCH

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

(2011) Masanori Kawaguchi et al.   CIRCULATION

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

(2011) Christine A. Robson-Doucette et al.   DIABETES

Oxidative DNA damage and obesity in type 2 diabetes mellitus

(2011) Hayder A Al-Aubaidy et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Mitochondrial DNA and inflammatory diseases

(2011) Germaine Escames et al.   HUMAN GENETICS

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Inactivation and Reactivation of the Mitochondrial α-Ketoglutarate Dehydrogenase Complex

(2011) Qingli Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired expression of hypoxia-inducible factor-1α in cystic fibrosis airway epithelial cells – A role for HIF-1 in the pathophysiology of CF?

(2011) Claire Legendre et al.   Journal of Cystic Fibrosis

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

(2011) Ariel C. Bulua et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parthenolide inhibits ERK and AP-1 which are dysregulated and contribute to excessive IL-8 expression and secretion in cystic fibrosis cells

(2011) Aicha Saadane et al.   Journal of Inflammation-London

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

S14G-Humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice

(2011) Wenjun Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The role of UCP 1 in production of reactive oxygen species by mitochondria isolated from brown adipose tissue

(2010) Andrea Dlasková et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Disulfide bonds in ER protein folding and homeostasis

(2010) Matthias J Feige et al.   CURRENT OPINION IN CELL BIOLOGY

Mitochondrial shape changes: orchestrating cell pathophysiology

(2010) Silvia Campello et al.   EMBO REPORTS

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

(2010) Daniel C Lee et al.   Journal of Neuroinflammation

The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18

(2010) S. Jha et al.   JOURNAL OF NEUROSCIENCE

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

The cardioprotective effects elicited by p66Shc ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury

(2009) Andrea Carpi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Differential Effect of Saturated and Unsaturated Free Fatty Acids on the Generation of Monocyte Adhesion and Chemotactic Factors by Adipocytes: Dissociation of Adipocyte Hypertrophy From Inflammation

(2009) C. Y. Han et al.   DIABETES

Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition

(2009) Magali Dumont et al.   FREE RADICAL BIOLOGY AND MEDICINE

Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2Emission during Long-chain Fatty Acid Oxidation

(2009) Erin L. Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1  in Long-Lived Mclk1+/- Mouse Mutants

(2009) D. Wang et al.   JOURNAL OF IMMUNOLOGY

Distinct neuroinflammatory profile in post-mortem human Huntingtonʼs disease

(2009) Aurelio Silvestroni et al.   NEUROREPORT

IL1Bpolymorphisms modulate cystic fibrosis lung disease

(2009) Hara Levy et al.   PEDIATRIC PULMONOLOGY

Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis

(2009) A. Rimessi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

(2009) Michal Caspi Tal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma

(2009) H.-X. Hao et al.   SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Fhit Interaction with Ferredoxin Reductase Triggers Generation of Reactive Oxygen Species and Apoptosis of Cancer Cells

(2008) Francesco Trapasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells

(2008) Rafael Herling Lambertucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Preventing hypoxia/reoxygenation damage to hepatocytes by p66shc ablation: Up-regulation of anti-oxidant and anti-apoptotic proteins

(2008) Sanae Haga et al.   JOURNAL OF HEPATOLOGY

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE