Stem Cell Mechanobiology and the Role of Biomaterials in Governing Mechanotransduction and Matrix Production for Tissue Regeneration

Dense carbon-nanotube coating scaffolds stimulate osteogenic differentiation of mesenchymal stem cells

(2020) Hideki Mori et al.   PLoS One

Progressive Myofibril Reorganization of Human Cardiomyocytes on a Dynamic Nanotopographic Substrate

(2020) Shiyang Sun et al.   ACS Applied Materials & Interfaces

Engineered Full‐Length Fibronectin–Hyaluronic Acid Hydrogels for Stem Cell Engineering

(2020) Sara Trujillo et al.   Advanced Healthcare Materials

Cadherin mechanotransduction in leader-follower cell specification during collective migration

(2019) Antoine A. Khalil et al.   EXPERIMENTAL CELL RESEARCH

Signal Transduction across the Nuclear Envelope: Role of the LINC Complex in Bidirectional Signaling

(2019) Miki Hieda   Cells

SUN/KASH interactions facilitate force transmission across the nuclear envelope

(2019) Hongyan Hao et al.   Nucleus

Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments

(2019) Hong-pyo Lee et al.   Nature Communications

TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension

(2019) Christopher L. Gilchrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recovery of stem cell proliferation by low intensity vibration under simulated microgravity requires LINC complex

(2019) H. Touchstone et al.   NPJ Microgravity

Extracellular matrix type modulates mechanotransduction of stem cells

(2019) Alice E. Stanton et al.   Acta Biomaterialia

The role of biomaterials in stem cell-based regenerative medicine

(2019) Xiangnan Zhao et al.   Future Medicinal Chemistry

Are microtubules tension sensors?

(2019) Olivier Hamant et al.   Nature Communications

Innovative Tools for Mechanobiology: Unraveling Outside-In and Inside-Out Mechanotransduction

(2019) Danahe Mohammed et al.   Frontiers in Bioengineering and Biotechnology

The effect of pore size within fibrous scaffolds fabricated using melt electrowriting on human bone marrow stem cell osteogenesis

(2019) Conor Brennan et al.   Biomedical Materials

Insight into Mechanobiology: How Stem Cells Feel Mechanical Forces and Orchestrate Biological Functions

(2019) Chiara Argentati et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

From macroscopic mechanics to cell-effective stiffness within highly aligned macroporous collagen scaffolds

(2019) A. Herrera et al.   Materials Science & Engineering C-Materials for Biological Applications

Cell adhesion and culture medium dependent changes in the high frequency mechanical vibration induced proliferation, osteogenesis, and intracellular organization of human adipose stem cells

(2019) H.T. Halonen et al.   Journal of the Mechanical Behavior of Biomedical Materials

Three-dimensional imaging of cell and extracellular matrix elasticity using quantitative micro-elastography

(2019) Matt S. Hepburn et al.   Biomedical Optics Express

Interconnectable Dynamic Compression Bioreactors for Combinatorial Screening of Cell Mechanobiology in Three Dimensions

(2018) Jungmok Seo et al.   ACS Applied Materials & Interfaces

Mediating human stem cell behaviour via defined fibrous architectures by melt electrospinning writing

(2018) Kian F. Eichholz et al.   Acta Biomaterialia

Mechanotransduction by the Actin Cytoskeleton: Converting Mechanical Stimuli into Biochemical Signals

(2018) Andrew R. Harris et al.   Annual Review of Biophysics

Integrin diversity brings specificity in mechanotransduction

(2018) Shailaja Seetharaman et al.   BIOLOGY OF THE CELL

Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates

(2018) Matthew G. Haugh et al.   BIOMATERIALS

Mechanotransduction via the LINC complex regulates DNA replication in myonuclei

(2018) Shuoshuo Wang et al.   JOURNAL OF CELL BIOLOGY

Attachment and spatial organisation of human mesenchymal stem cells on poly(ethylene glycol) hydrogels

(2018) Aman S. Chahal et al.   Journal of the Mechanical Behavior of Biomedical Materials

Biomaterial surface energy-driven ligand assembly strongly regulates stem cell mechanosensitivity and fate on very soft substrates

(2018) Tojo Razafiarison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rho/Rho-associated protein kinase signaling pathway‑mediated downregulation of runt-related transcription factor 2 expression promotes the differentiation of dental pulp stem cells into odontoblasts

(2018) Xiaoqing Huang et al.   Experimental and Therapeutic Medicine

TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium

(2018) Michele A. Corrigan et al.   Scientific Reports

Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells

(2018) Sangkyun Cho et al.   Nucleus

Cellular Mechanotransduction: From Tension to Function

(2018) Fabiana Martino et al.   Frontiers in Physiology

Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells

(2018) Sangkyun Cho et al.   Nucleus

Cellular Durotaxis Revisited: Initial-Position-Dependent Determination of the Threshold Stiffness Gradient to Induce Durotaxis

(2018) Kousuke Moriyama et al.   LANGMUIR

Focal Adhesion Kinase and ROCK Signaling Are Switch-Like Regulators of Human Adipose Stem Cell Differentiation towards Osteogenic and Adipogenic Lineages

(2018) Laura Hyväri et al.   Stem Cells International

Mesenchymal stem cell mechanotransduction is cAMP dependent and regulated by adenylyl cyclase 6 and the primary cilium

(2018) Gillian P. Johnson et al.   JOURNAL OF CELL SCIENCE

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

(2018) Noboru Ishiyama et al.   Nature Communications

The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids

(2017) F.E. Griffin et al.   JOURNAL OF BIOMECHANICS

Mechanosensing by the nucleus: From pathways to scaling relationships

(2017) Sangkyun Cho et al.   JOURNAL OF CELL BIOLOGY

Mechanical stimulations on human bone marrow mesenchymal stem cells enhance cells differentiation in a three-dimensional layered scaffold

(2017) Jessica Schiavi et al.   Journal of Tissue Engineering and Regenerative Medicine

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels

(2017) William J. Hadden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mimicking the Biochemical and Mechanical Extracellular Environment of the Endochondral Ossification Process to Enhance the In Vitro Mineralization Potential of Human Mesenchymal Stem Cells

(2017) Fiona E. Freeman et al.   TISSUE ENGINEERING PART A

Autonomous osteogenic differentiation of hASCs encapsulated in methacrylated gellan-gum hydrogels

(2016) Mariana B. Oliveira et al.   Acta Biomaterialia

Extracellular matrix structure

(2016) Achilleas D. Theocharis et al.   ADVANCED DRUG DELIVERY REVIEWS

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Capturing extracellular matrix properties in vitro: Microengineering materials to decipher cell and tissue level processes

(2016) Amr A Abdeen et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism

(2016) Julia C. Chen et al.   FASEB JOURNAL

Concise Review: Primary Cilia: Control Centers for Stem Cell Lineage Specification and Potential Targets for Cell-Based Therapies

(2016) Josephine C. Bodle et al.   STEM CELLS

Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

(2016) Xue Yuan et al.   Nature Communications

TGFβ1 – induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner

(2016) Marie-Noëlle Labour et al.   Scientific Reports

Single cell active force generation under dynamic loading – Part II: Active modelling insights

(2015) N.H. Reynolds et al.   Acta Biomaterialia

A guide to mechanobiology: Where biology and physics meet

(2015) Karin A. Jansen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

On human pluripotent stem cell control: The rise of 3D bioengineering and mechanobiology

(2015) Yue Shao et al.   BIOMATERIALS

The Effect of Substrate Stiffness, Thickness, and Cross-Linking Density on Osteogenic Cell Behavior

(2015) Conleth A. Mullen et al.   BIOPHYSICAL JOURNAL

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

(2015) Nathaniel Huebsch et al.   NATURE MATERIALS

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

(2015) Alexandre J. S. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the role of the actin cytoskeleton and nucleus in the biomechanical response of spread cells

(2014) Noel H. Reynolds et al.   BIOMATERIALS

KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus

(2014) GW Gant Luxton et al.   CURRENT OPINION IN CELL BIOLOGY

The Hippo signaling pathway in stem cell biology and cancer

(2014) J.-S. Mo et al.   EMBO REPORTS

Extracellular matrix elasticity and topography: Material-based cues that affect cell function via conserved mechanisms

(2014) Isaac A. Janson et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Cell morphology and focal adhesion location alters internal cell stress

(2014) C. A. Mullen et al.   Journal of the Royal Society Interface

Revisiting the matricellular concept

(2014) Joanne E. Murphy-Ullrich et al.   MATRIX BIOLOGY

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Retrograde flow of cadherins in collective cell migration

(2014) Eishu Hirata et al.   NATURE CELL BIOLOGY

Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells

(2014) Yubing Sun et al.   NATURE MATERIALS

Interplay of matrix stiffness and protein tethering in stem cell differentiation

(2014) Jessica H. Wen et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

(2014) Masatoshi Takeichi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The p38α MAPK Function in Osteoprecursors Is Required for Bone Formation and Bone Homeostasis in Adult Mice

(2014) Edgardo Rodríguez-Carballo et al.   PLoS One

Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia

(2014) James A.L. Brown et al.   Stem Cell Research

Actomyosin-dependent formation of the mechanosensitive talin–vinculin complex reinforces actin anchoring

(2014) Corina Ciobanasu et al.   Nature Communications

Rewiring mesenchymal stem cell lineage specification by switching the biophysical microenvironment

(2014) Junmin Lee et al.   Scientific Reports

Directing stem cell fate on hydrogel substrates by controlling cell geometry, matrix mechanics and adhesion ligand composition

(2013) Junmin Lee et al.   BIOMATERIALS

Cellular contractility and substrate elasticity: a numerical investigation of the actin cytoskeleton and cell adhesion

(2013) William Ronan et al.   Biomechanics and Modeling in Mechanobiology

Nonlinear Strain Stiffening Is Not Sufficient to Explain How Far Cells Can Feel on Fibrous Protein Gels

(2013) Mathilda S. Rudnicki et al.   BIOPHYSICAL JOURNAL

Experimental and Computational Investigation of the Role of Stress Fiber Contractility in the Resistance of Osteoblasts to Compression

(2013) P. P. Weafer et al.   BULLETIN OF MATHEMATICAL BIOLOGY

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

Necrotic and apoptotic cells serve as nuclei for calcification on osteoblastic differentiation of human mesenchymal stem cellsin vitro

(2013) Hirofumi Fujita et al.   CELL BIOCHEMISTRY AND FUNCTION

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Simulation of the Mechanical Response of Cells on Micropost Substrates

(2013) William Ronan et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Cyclic hydrostatic pressure promotes a stable cartilage phenotype and enhances the functional development of cartilaginous grafts engineered using multipotent stromal cells isolated from bone marrow and infrapatellar fat pad

(2013) S.F. Carroll et al.   JOURNAL OF BIOMECHANICS

Mechanotransduction at focal adhesions: integrating cytoskeletal mechanics in migrating cells

(2013) Jean-Cheng Kuo   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation

(2013) C.A. Mullen et al.   Journal of the Mechanical Behavior of Biomedical Materials

Mesenchymal stem cell mechanobiology and emerging experimental platforms

(2013) L. MacQueen et al.   Journal of the Royal Society Interface

A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems

(2013) T. J. Vaughan et al.   Journal of the Royal Society Interface

Substrate Stiffness Regulates Cellular Uptake of Nanoparticles

(2013) Changjin Huang et al.   NANO LETTERS

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

Inhibition of ROCK–Myosin II Signaling Pathway Enables Culturing of Human Pluripotent Stem Cells on Microcarriers Without Extracellular Matrix Coating

(2013) Allen Kuan-Liang Chen et al.   TISSUE ENGINEERING PART C-METHODS

Mechanics of spreading cells probed by atomic force microscopy

(2013) A. Pietuch et al.   Open Biology

Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition

(2013) Marcello Pilia et al.   Journal of Biological Engineering

Glycosaminoglycan-Binding Hydrogels Enable Mechanical Control of Human Pluripotent Stem Cell Self-Renewal

(2012) Samira Musah et al.   ACS Nano

The influence and interactions of substrate thickness, organization and dimensionality on cell morphology and migration

(2012) Chia-hsiang Feng et al.   Acta Biomaterialia

Effects of mechanical forces and stretch on intercellular gap junction coupling

(2012) Aida Salameh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Biomechanics of early cardiac development

(2012) Sevan Goenezen et al.   Biomechanics and Modeling in Mechanobiology

Contractile Equilibration of Single Cells to Step Changes in Extracellular Stiffness

(2012) Ailey Crow et al.   BIOPHYSICAL JOURNAL

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

The p38α MAPK positively regulates osteoblast function and postnatal bone acquisition

(2012) Cyril Thouverey et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanical regulation of signaling pathways in bone

(2012) William R. Thompson et al.   GENE

Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells

(2012) Albert J. Keung et al.   Integrative Biology

Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells

(2012) Florian Rehfeldt et al.   Integrative Biology

Force transduction and strain dynamics in actin stress fibres in response to nanonewton forces

(2012) L. Guolla et al.   JOURNAL OF CELL SCIENCE

Numerical investigation of the active role of the actin cytoskeleton in the compression resistance of cells

(2012) William Ronan et al.   Journal of the Mechanical Behavior of Biomedical Materials

The effect of remodelling and contractility of the actin cytoskeleton on the shear resistance of single cells: a computational and experimental investigation

(2012) E. P. Dowling et al.   Journal of the Royal Society Interface

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Mechanics Regulates Fate Decisions of Human Embryonic Stem Cells

(2012) Yubing Sun et al.   PLoS One

Substrate Stiffness and Oxygen as Regulators of Stem Cell Differentiation during Skeletal Tissue Regeneration: A Mechanobiological Model

(2012) Darren Paul Burke et al.   PLoS One

Primary Cilia-Mediated Mechanotransduction in Human Mesenchymal Stem Cells

(2012) David A. Hoey et al.   STEM CELLS

Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics

(2012) Murat Guvendiren et al.   Nature Communications

The Primary Cilium as a Novel Extracellular Sensor in Bone

(2012) David A. Hoey et al.   Frontiers in Endocrinology

Promotion of osteoblast differentiation in 3D biomaterial micro-chip arrays comprising fibronectin-coated poly(methyl methacrylate) polycarbonate

(2011) Brigitte Altmann et al.   BIOMATERIALS

A cell-instructive hydrogel to regulate malignancy of 3D tumor spheroids with matrix rigidity

(2011) Youyun Liang et al.   BIOMATERIALS

The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-β

(2011) Jennifer S. Park et al.   BIOMATERIALS

Mechanical derivation of functional myotubes from adipose-derived stem cells

(2011) Yu Suk Choi et al.   BIOMATERIALS

TRANSDUCTION OF STRAIN TO CELLS SEEDED ONTO SCAFFOLDS EXPOSED TO UNIAXIAL STRETCHING: A THREE DIMENSIONAL FINITE ELEMENT STUDY

(2011) AMBER RATH STERN et al.   Journal of Mechanics in Medicine and Biology

The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells

(2011) E.G. Meyer et al.   Journal of the Mechanical Behavior of Biomedical Materials

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Three-dimensional biomaterials for the study of human pluripotent stem cells

(2011) Thomas P Kraehenbuehl et al.   NATURE METHODS

Mechano-sensing and cell migration: a 3D model approach

(2011) C Borau et al.   PHYSICAL BIOLOGY

ROCK Inhibitor Y-27632 Suppresses Dissociation-Induced Apoptosis of Murine Prostate Stem/Progenitor Cells and Increases Their Cloning Efficiency

(2011) Li Zhang et al.   PLoS One

Substrate stiffness and contractile behaviour modulate the functional maturation of osteoblasts on a collagen–GAG scaffold

(2010) Michael B. Keogh et al.   Acta Biomaterialia

Tensile Strain as a Regulator of Mesenchymal Stem Cell Osteogenesis

(2010) E. M. Kearney et al.   ANNALS OF BIOMEDICAL ENGINEERING

Thickness sensing of hMSCs on collagen gel directs stem cell fate

(2010) Wen Shing Leong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osteogenesis and angiogenesis of tissue-engineered bone constructed by prevascularized β-tricalcium phosphate scaffold and mesenchymal stem cells

(2010) Le Wang et al.   BIOMATERIALS

Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension

(2010) Sapun H. Parekh et al.   BIOMATERIALS

Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro

(2010) Jennifer L. Young et al.   BIOMATERIALS

Steady and Oscillatory Fluid Flows Produce a Similar Osteogenic Phenotype

(2010) N. Case et al.   CALCIFIED TISSUE INTERNATIONAL

Actin-Myosin Contractility Is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells

(2010) Guokai Chen et al.   Cell Stem Cell

Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

(2010) Masatoshi Ohgushi et al.   Cell Stem Cell

The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment

(2010) Padmaja Tummala et al.   Cellular and Molecular Bioengineering

Cytoskeletal Cross-linking and Bundling in Motor-Independent Contraction

(2010) Sean X. Sun et al.   CURRENT BIOLOGY

Mechanical control of tissue and organ development

(2010) T. Mammoto et al.   DEVELOPMENT

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

(2010) Matthew B. Greenblatt et al.   JOURNAL OF CLINICAL INVESTIGATION

FAK Pathway Regulates PGE2 Production in Compressed Periodontal Ligament Cells

(2010) Y.-G. Kang et al.   JOURNAL OF DENTAL RESEARCH

Osteogenic Responses of Human Mesenchymal Stromal Cells to Static Stretch

(2010) I.S. Kim et al.   JOURNAL OF DENTAL RESEARCH

NPY promotes chemokinesis and neurogenesis in the rat subventricular zone

(2010) Nathalie Thiriet et al.   JOURNAL OF NEUROCHEMISTRY

How deeply cells feel: methods for thin gels

(2010) Amnon Buxboim et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

(2010) Jeff Holst et al.   NATURE BIOTECHNOLOGY

Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells

(2010) Ying Mei et al.   NATURE MATERIALS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Nonlinear viscoelasticity of adherent cells is controlled by cytoskeletal tension

(2010) Philip Kollmannsberger et al.   Soft Matter

Crosslinking and Mechanical Properties Significantly Influence Cell Attachment, Proliferation, and Migration Within Collagen Glycosaminoglycan Scaffolds

(2010) Matthew G. Haugh et al.   TISSUE ENGINEERING PART A

Ossifying Bone Marrow Explant Culture as a Three-Dimensional Mechanoresponsive In Vitro Model of Osteogenesis

(2010) Umut Atakan Gurkan et al.   TISSUE ENGINEERING PART A

Mesenchymal Stem Cell Mechanobiology

(2010) Alesha B. Castillo et al.   Current Osteoporosis Reports

Carbon nanofibers and carbon nanotubes in regenerative medicine

(2009) Phong A. Tran et al.   ADVANCED DRUG DELIVERY REVIEWS

Osteogenic Effects of Rest Inserted and Continuous Cyclic Tensile Strain on hASC Lines with Disparate Osteodifferentiation Capabilities

(2009) Ariel D. Hanson et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mechanisms of Stem Cell Self-Renewal

(2009) He Shenghui et al.   Annual Review of Cell and Developmental Biology

The effect of substrate stiffness on adult neural stem cell behavior

(2009) Nic D. Leipzig et al.   BIOMATERIALS

Matrix Strains Induced by Cells: Computing How Far Cells Can Feel

(2009) Shamik Sen et al.   Cellular and Molecular Bioengineering

Stem cells, microenvironment mechanics, and growth factor activation

(2009) Rebeca M Tenney et al.   CURRENT OPINION IN CELL BIOLOGY

Directing bone marrow-derived stromal cell function with mechanics

(2009) E. Potier et al.   JOURNAL OF BIOMECHANICS

The mechanical integrin cycle

(2009) E. Puklin-Faucher et al.   JOURNAL OF CELL SCIENCE

Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics

(2009) E. J. Arnsdorf et al.   JOURNAL OF CELL SCIENCE

Regulation of stemness and stem cell niche of mesenchymal stem cells: Implications in tumorigenesis and metastasis

(2009) Nastaran Z. Kuhn et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanobiological response of tendon stem cells: Implications of tendon homeostasis and pathogenesis of tendinopathy

(2009) Jianying Zhang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Responsiveness of human bone marrow stromal cells to shear stress

(2009) Maritie Grellier et al.   Journal of Tissue Engineering and Regenerative Medicine

Simulation of the contractile response of cells on an array of micro-posts

(2009) J. P. McGarry et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

The Effect of Hydrostatic Pressure on Three-Dimensional Chondroinduction of Human Adipose–Derived Stem Cells

(2009) Rei Ogawa et al.   TISSUE ENGINEERING PART A

Cartilage Tissue Engineering: Towards a Biomaterial-Assisted Mesenchymal Stem Cell Therapy

(2009) Claire Vinatier et al.   Current Stem Cell Research & Therapy

Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation

(2008) Andrew S. Rowlands et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hydrostatic Pressure Enhances Chondrogenic Differentiation of Human Bone Marrow Stromal Cells in Osteochondrogenic Medium

(2008) Diane R. Wagner et al.   ANNALS OF BIOMEDICAL ENGINEERING

The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages

(2008) Jingwei Xie et al.   BIOMATERIALS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Mechanical Strain Inhibits Adipogenesis in Mesenchymal Stem Cells by Stimulating a Durable β-Catenin Signal

(2008) Buer Sen et al.   ENDOCRINOLOGY

Mechanical strain induces osteogenic differentiation: Cbfa1 and Ets-1 expression in stretched rat mesenchymal stem cells

(2008) M.-C. Qi et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

A Finite Element Prediction of Strain on Cells in a Highly Porous Collagen-Glycosaminoglycan Scaffold

(2008) A. J. F. Stops et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering

(2008) Claire M. Tierney et al.   Journal of the Mechanical Behavior of Biomedical Materials

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Influence of finite thickness and stiffness on cellular adhesion-induced deformation of compliant substrata

(2008) John M. Maloney et al.   PHYSICAL REVIEW E

Role of Gap Junctions in Embryonic and Somatic Stem Cells

(2008) Raymond C. B. Wong et al.   Stem Cell Reviews and Reports

Effect of Intermittent Shear Stress on Mechanotransductive Signaling and Osteoblastic Differentiation of Bone Marrow Stromal Cells

(2008) Michelle R. Kreke et al.   TISSUE ENGINEERING PART A

Biomaterials for stem cell differentiation

(2007) Eileen Dawson et al.   ADVANCED DRUG DELIVERY REVIEWS

A dynamic pattern of mechanical stimulation promotes ossification in avian embryonic long bones

(2007) Niamh C. Nowlan et al.   JOURNAL OF BIOMECHANICS