Substrate Stiffness and Oxygen as Regulators of Stem Cell Differentiation during Skeletal Tissue Regeneration: A Mechanobiological Model

Cell–matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure

(2012) A.J. Steward et al.   Acta Biomaterialia

Temporal and Spatial Vascularization Patterns of Unions and Nonunions: Role of Vascular Endothelial Growth Factor and Bone Morphogenetic Proteins

(2012) P Garcia et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells

(2011) Eamon J. Sheehy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-β

(2011) Jennifer S. Park et al.   BIOMATERIALS

Simulation of fracture healing in the tibia: Mechanoregulation of cell activity using a lattice modeling approach

(2011) Damien P. Byrne et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mechanical regulation of vascular growth and tissue regeneration in vivo

(2011) J. D. Boerckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Compressive Loading Enhances Cartilage Matrix Synthesis and Distribution and Suppresses Hypertrophy in hMSC-Laden Hyaluronic Acid Hydrogels

(2011) Liming Bian et al.   TISSUE ENGINEERING PART A

A hybrid bioregulatory model of angiogenesis during bone fracture healing

(2010) Véronique Peiffer et al.   Biomechanics and Modeling in Mechanobiology

The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells

(2010) Daniel J. Kelly et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells

(2010) Christina Holzwarth et al.   BMC CELL BIOLOGY

A numerical model of the fracture healing process that describes tissue development and revascularisation

(2010) U. Simon et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression

(2010) Eric G. Meyer et al.   JOURNAL OF BIOMECHANICS

Temporal tissue patterns in bone healing of sheep

(2010) Andreas Vetter et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

A mechano-regulation model of fracture repair in vertebral bodies

(2010) Antonio Boccaccio et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes

(2010) C.T. Buckley et al.   OSTEOARTHRITIS AND CARTILAGE

Mechanical Loading Affects Angiogenesis and Osteogenesis in an In Vivo Bone Chamber: A Modeling Study

(2010) Liesbet Geris et al.   TISSUE ENGINEERING PART A

Occurrence and Treatment of Bone Atrophic Non-Unions Investigated by an Integrative Approach

(2010) Liesbet Geris et al.   PLoS Computational Biology

Differential effects of hypoxia on osteochondrogenic potential of human adipose-derived stem cells

(2009) Christophe Merceron et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel

(2009) Y. Shona Pek et al.   BIOMATERIALS

Assessment of a mechano-regulation theory of skeletal tissue differentiation in an in vivo model of mechanically induced cartilage formation

(2009) Lauren Nicole Miller Hayward et al.   Biomechanics and Modeling in Mechanobiology

Mechano-regulation of mesenchymal stem cell differentiation and collagen organisation during skeletal tissue repair

(2009) Thomas Nagel et al.   Biomechanics and Modeling in Mechanobiology

Hypoxia and stem cell-based engineering of mesenchymal tissues

(2009) Teng Ma et al.   BIOTECHNOLOGY PROGRESS

Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation

(2009) A. Krinner et al.   CELL PROLIFERATION

Simulation of the nutrient supply in fracture healing

(2009) G. Chen et al.   JOURNAL OF BIOMECHANICS

Thrombospondin-2 Influences the Proportion of Cartilage and Bone During Fracture Healing

(2009) Douglas K Taylor et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modeling approach

(2009) Hanifeh Khayyeri et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

A Mechanobiological Model for Tissue Differentiation that Includes Angiogenesis: A Lattice-Based Modeling Approach

(2008) Sara Checa et al.   ANNALS OF BIOMEDICAL ENGINEERING

Pressure, oxygen tension and temperature in the periosteal callus during bone healing—An in vivo study in sheep

(2008) Devakara R. Epari et al.   BONE

Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: A role for AKT and hypoxia‐inducible factor (HIF)‐1α

(2008) Manoj Kanichai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endochondral ossification: How cartilage is converted into bone in the developing skeleton

(2007) E.J. Mackie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiogenesis in bone fracture healing: A bioregulatory model

(2007) Liesbet Geris et al.   JOURNAL OF THEORETICAL BIOLOGY