Cellular Mechanotransduction: From Tension to Function

Integrin diversity brings specificity in mechanotransduction

(2018) Shailaja Seetharaman et al.   BIOLOGY OF THE CELL

FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

(2018) Dariusz Lachowski et al.   FASEB JOURNAL

Nanopillar force measurements reveal actin-cap-mediated YAP mechanotransduction

(2018) Jau-Ye Shiu et al.   NATURE CELL BIOLOGY

Conformational states during vinculin unlocking differentially regulate focal adhesion properties

(2018) Dror S. Chorev et al.   Scientific Reports

Integrin-bound talin head inhibits actin filament barbed-end elongation

(2017) Corina Ciobanasu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanosensing by the nucleus: From pathways to scaling relationships

(2017) Sangkyun Cho et al.   JOURNAL OF CELL BIOLOGY

Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA

(2017) Yaming Jiu et al.   JOURNAL OF CELL SCIENCE

Force-dependent breaching of the basement membrane

(2017) Tammy T. Chang et al.   MATRIX BIOLOGY

Effects of substrate stiffness and actomyosin contractility on coupling between force transmission and vinculin–paxillin recruitment at single focal adhesions

(2017) Dennis W. Zhou et al.   MOLECULAR BIOLOGY OF THE CELL

Force loading explains spatial sensing of ligands by cells

(2017) Roger Oria et al.   NATURE

Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

(2017) Nico Strohmeyer et al.   NATURE MATERIALS

Mechanosensing of matrix by stem cells: From matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo

(2017) Lucas Smith et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanism of microtubule stabilization by taccalonolide AJ

(2017) Yuxi Wang et al.   Nature Communications

YAP regulates cell mechanics by controlling focal adhesion assembly

(2017) Giorgia Nardone et al.   Nature Communications

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs

(2017) Daniel Brayson et al.   Nucleus

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs

(2017) Daniel Brayson et al.   Nucleus

Mechanical stability of talin rod controls cell migration and substrate sensing

(2017) Rolle Rahikainen et al.   Scientific Reports

Stiffness-dependent motility and proliferation uncoupled by deletion of CD44

(2017) Ziba Razinia et al.   Scientific Reports

All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing

(2016) Alexander William M. Haining et al.   ACS Nano

αvβ3 integrins negatively regulate cellular forces by phosphorylation of its distal NPXY site

(2016) Rachel Milloud et al.   BIOLOGY OF THE CELL

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains

(2016) Aneesh R. Sathe et al.   JOURNAL OF CELL SCIENCE

From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance

(2016) Anh Tuan Nguyen et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Interplay between Solo and keratin filaments is crucial for mechanical force–induced stress fiber reinforcement

(2016) Sachiko Fujiwara et al.   MOLECULAR BIOLOGY OF THE CELL

α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions

(2016) Giovanni Meacci et al.   MOLECULAR BIOLOGY OF THE CELL

Vascular smooth muscle cell durotaxis depends on extracellular matrix composition

(2016) Christopher D. Hartman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The integrin–talin complex under force

(2016) Jan Neumann et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Forcing through Tumor Metastasis: The Interplay between Tissue Rigidity and Epithelial–Mesenchymal Transition

(2016) Spencer C. Wei et al.   TRENDS IN CELL BIOLOGY

The mechanical response of talin

(2016) Mingxi Yao et al.   Nature Communications

Skeletal Muscle Laminopathies: A Review of Clinical and Molecular Features

(2016) Lorenzo Maggi et al.   Cells

The alterations in the extracellular matrix composition guide the repair of damaged liver tissue

(2016) Mariliis Klaas et al.   Scientific Reports

Matrix stiffness-modulated proliferation and secretory function of the airway smooth muscle cells

(2015) Artem Shkumatov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cytoskeletal tension induces the polarized architecture of the nucleus

(2015) Dong-Hwee Kim et al.   BIOMATERIALS

Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells

(2015) Tristan P. Driscoll et al.   BIOPHYSICAL JOURNAL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Substrate Stiffness Affects Human Keratinocyte Colony Formation

(2015) Hoda Zarkoob et al.   Cellular and Molecular Bioengineering

Lamins: the structure and protein complexes

(2015) Yosef Gruenbaum et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site

(2015) Ruifang Qin et al.   Cytoskeleton

Lamins at the crossroads of mechanosignaling

(2015) Selma Osmanagic-Myers et al.   GENES & DEVELOPMENT

Nuclear pore proteins and the control of genome functions

(2015) Arkaitz Ibarra et al.   GENES & DEVELOPMENT

Nuclear F-actin Formation and Reorganization upon Cell Spreading

(2015) Matthias Plessner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crosstalk between Hippo and TGFβ: Subcellular Localization of YAP/TAZ/Smad Complexes

(2015) Karin Grannas et al.   JOURNAL OF MOLECULAR BIOLOGY

Stiffness of cancer cells measured with an AFM indentation method

(2015) Kozaburo Hayashi et al.   Journal of the Mechanical Behavior of Biomedical Materials

Super-resolution links vinculin localization to function in focal adhesions

(2015) Grégory Giannone   NATURE CELL BIOLOGY

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell

(2015) Srujana Neelam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

(2015) Yuka Morikawa et al.   Science Signaling

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

Tissue Stiffness Dictates Development, Homeostasis, and Disease Progression

(2015) Andrew M Handorf et al.   Organogenesis

Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers

(2015) Yaming Jiu et al.   Cell Reports

Mechanism of Focal Adhesion Kinase Mechanosensing

(2015) Jing Zhou et al.   PLoS Computational Biology

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

(2015) Yuka Morikawa et al.   Science Signaling

Hippo Pathway Effectors Control Cardiac Progenitor Cell Fate by Acting as Dynamic Sensors of Substrate Mechanics and Nanostructure

(2014) Diogo Mosqueira et al.   ACS Nano

Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

(2014) Hiroaki Hirata et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Talin Dimer Structure Orientation Is Mechanically Regulated

(2014) Javad Golji et al.   BIOPHYSICAL JOURNAL

Tensional Homeostasis in Single Fibroblasts

(2014) Kevin D. Webster et al.   BIOPHYSICAL JOURNAL

Force Engages Vinculin and Promotes Tumor Progression by Enhancing PI3K Activation of Phosphatidylinositol (3,4,5)-Triphosphate

(2014) Matthew G. Rubashkin et al.   CANCER RESEARCH

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

(2014) Amnon Buxboim et al.   CURRENT BIOLOGY

Mechanosensors in integrin signaling: The emerging role of p130Cas

(2014) Radoslav Janoštiak et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies

(2014) Z.-J. Chen et al.   JOURNAL OF CELL SCIENCE

Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors

(2014) A. T. Bertrand et al.   JOURNAL OF CELL SCIENCE

The role of the interaction of the vinculin proline-rich linker region with vinexin   in sensing the stiffness of the extracellular matrix

(2014) H. Yamashita et al.   JOURNAL OF CELL SCIENCE

Fibrotic extracellular matrix activates a profibrotic positive feedback loop

(2014) Matthew W. Parker et al.   JOURNAL OF CLINICAL INVESTIGATION

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis

(2014) J-K Jin et al.   ONCOGENE

Microtubules stabilize cell polarity by localizing rear signals

(2014) Jian Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular mechanosensing: Getting to the nucleus of it all

(2014) Gregory R. Fedorchak et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis

(2014) J. Lauriol et al.   Science Signaling

A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling

(2014) Y. H. Bae et al.   Science Signaling

Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration

(2014) J. W. Haskins et al.   Science Signaling

Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression

(2014) Youhua Tan et al.   Nature Communications

Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

(2014) Peter Meinke et al.   PLoS Genetics

LINC complexes in health and disease

(2014) Alexandre Méjat   Nucleus

Diverse lamin-dependent mechanisms interact to control chromatin dynamics

(2014) Daria Camozzi et al.   Nucleus

Nanotopography Modulates Mechanotransduction of Stem Cells and Induces Differentiation through Focal Adhesion Kinase

(2013) Benjamin Kim Kiat Teo et al.   ACS Nano

Temporal changes in integrin-mediated cardiomyocyte adhesion secondary to chronic cardiac volume overload in rats

(2013) James A. Stewart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The ion channels to cytoskeleton connection as potential mechanism of mechanosensitivity

(2013) Boris Martinac   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The regulation of dynamic mechanical coupling between actin cytoskeleton and nucleus by matrix geometry

(2013) Qingsen Li et al.   BIOMATERIALS

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

(2013) Ludovic G. Vincent et al.   Biotechnology Journal

When Lamins Go Bad: Nuclear Structure and Disease

(2013) Katherine H. Schreiber et al.   CELL

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

Mechanosensitivity and compositional dynamics of cell–matrix adhesions

(2013) Herbert B Schiller et al.   EMBO REPORTS

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes

(2013) Masato Kajikawa et al.   HYPERTENSION

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain

(2013) Mark A. Smith et al.   PLoS One

C3 Rho-Inhibitor for Targeted Pharmacological Manipulation of Osteoclast-Like Cells

(2013) Andrea Tautzenberger et al.   PLoS One

How vinculin regulates force transmission

(2013) D. W. Dumbauld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

(2013) R. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin-dependent force transmission to the extracellular matrix by  -actinin triggers adhesion maturation

(2013) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

(2013) Allison B. Chambliss et al.   Scientific Reports

The Natural Product Cucurbitacin E Inhibits Depolymerization of Actin Filaments

(2012) Pia M. Sörensen et al.   ACS Chemical Biology

β1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses

(2012) Ruixia Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Structures of the lamin A/C R335W and E347K mutants: Implications for dilated cardiolaminopathies

(2012) Michela Bollati et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

From Mechanical Force to RhoA Activation

(2012) Elizabeth C. Lessey et al.   BIOCHEMISTRY

Mechanical Properties of β-Catenin Revealed by Single-Molecule Experiments

(2012) Alejandro Valbuena et al.   BIOPHYSICAL JOURNAL

Force-Induced Changes in Subnuclear Movement and Rheology

(2012) Elizabeth A. Booth-Gauthier et al.   BIOPHYSICAL JOURNAL

Mechanical Activation of Cells Induces Chromatin Remodeling Preceding MKL Nuclear Transport

(2012) K. Venkatesan Iyer et al.   BIOPHYSICAL JOURNAL

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins

(2012) Brian A. Sosa et al.   CELL

Accumulation of the Inner Nuclear Envelope Protein Sun1 Is Pathogenic in Progeric and Dystrophic Laminopathies

(2012) Chia-Yen Chen et al.   CELL

ADF/Cofilin Regulates Actomyosin Assembly through Competitive Inhibition of Myosin II Binding to F-Actin

(2012) O'Neil Wiggan et al.   DEVELOPMENTAL CELL

Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study

(2012) Petra dos Santos et al.   Diagnostic Pathology

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)

(2012) J.-S. Mo et al.   GENES & DEVELOPMENT

Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells

(2012) Wei Chen et al.   JOURNAL OF CELL BIOLOGY

Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells

(2012) O. Jung et al.   JOURNAL OF CELL SCIENCE

Lamins at a glance

(2012) C. Y. Ho et al.   JOURNAL OF CELL SCIENCE

Actin stress fibers - assembly, dynamics and biological roles

(2012) S. Tojkander et al.   JOURNAL OF CELL SCIENCE

Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

(2012) Laura M. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Matrix Stiffness Regulates Endothelial Cell Proliferation through Septin 9

(2012) Yi-Ting Yeh et al.   PLoS One

Substrate Stiffness Modulates Gene Expression and Phenotype in Neonatal Cardiomyocytes In Vitro

(2012) Giancarlo Forte et al.   TISSUE ENGINEERING PART A

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function

(2011) Maria L. Lombardi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The effect of substrate microtopography on focal adhesion maturation and actin organization via the RhoA/ROCK pathway

(2011) Chang Ho Seo et al.   BIOMATERIALS

The LIM Domain of Zyxin Is Sufficient for Force-Induced Accumulation of Zyxin During Cell Migration

(2011) Arisa Uemura et al.   BIOPHYSICAL JOURNAL

Focal Adhesion Kinase Stabilizes the Cytoskeleton

(2011) Ben Fabry et al.   BIOPHYSICAL JOURNAL

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

(2011) Kimihide Hayakawa et al.   JOURNAL OF CELL BIOLOGY

Nucleoskeleton mechanics at a glance

(2011) K. N. Dahl et al.   JOURNAL OF CELL SCIENCE

RhoA protects the mouse heart against ischemia/reperfusion injury

(2011) Sunny Yang Xiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

External forces control mitotic spindle positioning

(2011) Jenny Fink et al.   NATURE CELL BIOLOGY

Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

(2011) Justin R. Tse et al.   PLoS One

High-Resolution Quantification of Focal Adhesion Spatiotemporal Dynamics in Living Cells

(2011) Mathew E. Berginski et al.   PLoS One

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components

(2011) N.-G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Actin Filament Treadmilling in Cell Motility

(2010) Beáta Bugyi et al.   Annual Review of Biophysics

Talin1 Promotes Tumor Invasion and Metastasis via Focal Adhesion Signaling and Anoikis Resistance

(2010) S. Sakamoto et al.   CANCER RESEARCH

Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

(2010) Sandra Krull et al.   EMBO JOURNAL

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei

(2010) Heidi N. Fridolfsson et al.   JOURNAL OF CELL BIOLOGY

Cytoskeletal coherence requires myosin-IIA contractility

(2010) Y. Cai et al.   JOURNAL OF CELL SCIENCE

Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy

(2010) Vesna Nikolova-Krstevski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Targeting anoikis resistance in prostate cancer metastasis

(2010) Shinichi Sakamoto et al.   MOLECULAR ASPECTS OF MEDICINE

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Complexity of the Tensegrity Structure for Dynamic Energy and Force Distribution of Cytoskeleton during Cell Spreading

(2010) Ting-Jung Chen et al.   PLoS One

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

(2010) E. S. Folker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Influence of substrate stiffness on the phenotype of heart cells

(2009) Bashir Bhana et al.   BIOTECHNOLOGY AND BIOENGINEERING

Nuclei Take a Position: Managing Nuclear Location

(2009) Brian Burke et al.   DEVELOPMENTAL CELL

Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif

(2009) Tsutomu Oka et al.   GENES TO CELLS

Structural Determinants of Integrin Binding to the Talin Rod

(2009) Alexandre R. Gingras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

(2009) J. Colombelli et al.   JOURNAL OF CELL SCIENCE

Nuclear lamins: key regulators of nuclear structure and activities

(2009) Miron Prokocimer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Laminopathies and the long strange trip from basic cell biology to therapy

(2009) Howard J. Worman et al.   JOURNAL OF CLINICAL INVESTIGATION

Focal Adhesion Kinase Modulates Cell Adhesion Strengthening via Integrin Activation

(2009) Kristin E. Michael et al.   MOLECULAR BIOLOGY OF THE CELL

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Effects of a Rho kinase inhibitor on pressure overload induced cardiac hypertrophy and associated diastolic dysfunction

(2008) Arintaya Phrommintikul et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4motif: evidence that nuclear paxillin promotes cell proliferation

(2008) Jing-Ming Dong et al.   BIOCHEMICAL JOURNAL

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE

Mechanisms of actin stress fibre assembly

(2008) P. NAUMANEN et al.   JOURNAL OF MICROSCOPY

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Criticality of the Biological and Physical Stimuli Array Inducing Resident Cardiac Stem Cell Determination

(2008) Giancarlo Forte et al.   STEM CELLS

Mechano-Coupling and Regulation of Contractility by the Vinculin Tail Domain

(2007) Claudia Tanja Mierke et al.   BIOPHYSICAL JOURNAL