Primary Cilia-Mediated Mechanotransduction in Human Mesenchymal Stem Cells

Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading

(2012) Sara Temiyasathit et al.   PLoS One

A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

(2011) David A. Hoey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Primary cilia modulate Ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes

(2011) Yvonne Y. Shao et al.   BONE

Mechanisms regulating cilia growth and cilia function in endothelial cells

(2011) Shakila Abdul-Majeed et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The mechanics of the primary cilium: An intricate structure with complex function

(2011) David A. Hoey et al.   JOURNAL OF BIOMECHANICS

Flow perfusion culture of human mesenchymal stem cells on coralline hydroxyapatite scaffolds with various pore sizes

(2011) Lea Bjerre et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of the polycytin-primary cilia complex in bone development and mechanosensing

(2010) Z.S. Xiao et al.   Annals of the New York Academy of Sciences

Mechanisms for osteogenic differentiation of human mesenchymal stem cells induced by fluid shear stress

(2010) Liyue Liu et al.   Biomechanics and Modeling in Mechanobiology

Three hours of perfusion culture prior to 28 days of static culture, enhances osteogenesis by human cells in a collagen GAG scaffold

(2010) Michael B. Keogh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mechanobiology of embryonic skeletal development: Insights from animal models

(2010) Niamh C. Nowlan et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells

(2010) Daniel J. Kelly et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

β1 Integrins Mediate Mechanosensitive Signaling Pathways in Osteocytes

(2010) Julie B. Litzenberger et al.   CALCIFIED TISSUE INTERNATIONAL

The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment

(2010) Padmaja Tummala et al.   Cellular and Molecular Bioengineering

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells

(2010) Ronald Y. Kwon et al.   FASEB JOURNAL

Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo

(2010) M. R. Forwood   JOURNAL OF BONE AND MINERAL RESEARCH

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

Sonic Hedgehog Influences the Balance of Osteogenesis and Adipogenesis in Mouse Adipose-Derived Stromal Cells

(2010) Aaron W. James et al.   TISSUE ENGINEERING PART A

Influence of Shear Stress in Perfusion Bioreactor Cultures for the Development of Three-Dimensional Bone Tissue Constructs: A Review

(2010) Ryan J. McCoy et al.   TISSUE ENGINEERING PART B-REVIEWS

Mesenchymal Stem Cell Mechanobiology

(2010) Alesha B. Castillo et al.   Current Osteoporosis Reports

Mechanotherapy: how physical therapists' prescription of exercise promotes tissue repair

(2009) K M Khan et al.   BRITISH JOURNAL OF SPORTS MEDICINE

The neuronal primary cilium: Driver of neurogenesis and memory formation in the hippocampal dentate gyrus?

(2009) James F. Whitfield et al.   CELLULAR SIGNALLING

The Primary Cilium as a Complex Signaling Center

(2009) Nicolas F. Berbari et al.   CURRENT BIOLOGY

Conditional Disruption ofPkd1in Osteoblasts Results in Osteopenia Due to Direct Impairment of Bone Formation

(2009) Zhousheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oscillatory Flow-induced Proliferation of Osteoblast-like Cells Is Mediated by αvβ3and β1Integrins through Synergistic Interactions of Focal Adhesion Kinase and Shc with Phosphatidylinositol 3-Kinase and the Akt/mTOR/p70S6K Pathway

(2009) Ding-Yu Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Directing bone marrow-derived stromal cell function with mechanics

(2009) E. Potier et al.   JOURNAL OF BIOMECHANICS

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

(2009) C. A. Clement et al.   JOURNAL OF CELL SCIENCE

Adiponectin Stimulates Osteoblast Differentiation Through Induction of COX2 in Mesenchymal Progenitor Cells

(2009) Hyun Woo Lee et al.   STEM CELLS

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

(2008) Anatoliy I. Masyuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Mechanical Environment of Bone Marrow: A Review

(2008) Umut Atakan Gurkan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Flow perfusion culture of human mesenchymal stem cells on silicate-substituted tricalcium phosphate scaffolds

(2008) Lea Bjerre et al.   BIOMATERIALS

Focal Adhesion Kinase Is Important for Fluid Shear Stress–Induced Mechanotransduction in Osteoblasts

(2008) Suzanne RL Young et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery

(2008) Enko N. Kiprilov et al.   JOURNAL OF CELL BIOLOGY

Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells

(2008) Magali Plaisant et al.   STEM CELLS

Effects of fluid flow and calcium phosphate coating on human bone marrow stromal cells cultured in a defined 2D model system

(2007) S. Scaglione et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A