Mechanisms of melanocyte death in vitiligo

Vitiligo: Mechanisms of Pathogenesis and Treatment

(2020) Michael L. Frisoli et al.   Annual Review of Immunology

Regulatory T Cells and Human Disease

(2020) Shimon Sakaguchi et al.   Annual Review of Immunology

Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathway

(2020) Baoxiang Zhang et al.   CELL STRESS & CHAPERONES

Local heroes or villains: tissue-resident memory T cells in human health and disease

(2020) S. C. Sasson et al.   Cellular & Molecular Immunology

ATP-P2X7–Induced Inflammasome Activation Contributes to Melanocyte Death and CD8+ T-Cell Trafficking to the Skin in Vitiligo

(2020) Yuri Ahn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Homocysteine induces melanocytes apoptosis via PERK–eIF2α–CHOP pathway in vitiligo

(2020) Jiaxi Chen et al.   CLINICAL SCIENCE

Recent Progress and Future Directions: The Nano-Drug Delivery System for the Treatment of Vitiligo

(2020) Ming-Chen Sun et al.   International Journal of Nanomedicine

Molecular Hydrogen Protects Human Melanocytes from Oxidative Stress by Activating Nrf2 Signaling

(2020) Wei Fang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

JAK inhibitors reverse vitiligo in mice but do not deplete skin resident memory T cells

(2020) Vincent Azzolino et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial

(2020) David Rosmarin et al.   LANCET

Vitiligo as a skin memory disease: The need for early intervention with immunomodulating agents and a maintenance therapy to target resident memory T cells

(2019) Katia Boniface et al.   EXPERIMENTAL DERMATOLOGY

Perspectives of New Advances in the Pathogenesis of Vitiligo: From Oxidative Stress to Autoimmunity

(2019) Yinghan Wang et al.   MEDICAL SCIENCE MONITOR

Emerging role of immune cell network in autoimmune skin disorders: An update on pemphigus, vitiligo and psoriasis

(2019) Dayasagar Das et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Comprehensive lipidomic, metabolomic and proteomic profiling reveals the role of immune system in vitiligo

(2019) L. Liang et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Expression analysis of PD ‐1 and Tim‐3 immune checkpoint receptors in Vitiligo patients; positive association with disease activity

(2019) Ali Rahimi et al.   EXPERIMENTAL DERMATOLOGY

Extracellular fraction of adipose tissue as an innovative regenerative approach for vitiligo treatment

(2019) B. Bellei et al.   EXPERIMENTAL DERMATOLOGY

Oxidative stress-induced IL-15 transtrans-presentation in keratinocytes contributes to CD8+ T cells activation via JAK-STAT pathway in vitiligo

(2019) Xuguang Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Berberine protects immortalized line of human melanocytes from H2O2-induced oxidative stress via activation of Nrf2 and Mitf signaling pathway

(2019) Wei Jiang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Oxidative stress-induced HMGB1 release from melanocytes: a paracrine mechanism underlying the cutaneous inflammation in vitiligo

(2019) Tingting Cui et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

IL‐17A is not a treatment target in progressive vitiligo

(2019) Reinhart Speeckaert et al.   Pigment Cell & Melanoma Research

T cell pathology in skin inflammation

(2019) Robert Sabat et al.   Seminars in Immunopathology

Notch-1 Inhibition Promotes Immune Regulation in Transplantation via Treg-Dependent Mechanisms

(2019) Ciara N. Magee et al.   CIRCULATION

Deciphering the mechanism for induction of senescence-associated secretory phenotype (SASP) and its role in ageing and cancer development

(2019) Naoko Ohtani   JOURNAL OF BIOCHEMISTRY

Ginkgo biloba extract protects human melanocytes from H 2 O 2 ‐induced oxidative stress by activating Nrf2

(2019) Shaolong Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Role of Memory CD8+ T Cells in Vitiligo

(2019) Rebecca L. Riding et al.   JOURNAL OF IMMUNOLOGY

Skin‐resident memory T cells as a potential new therapeutic target in vitiligo and melanoma

(2019) Marcella Willemsen et al.   Pigment Cell & Melanoma Research

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo

(2019) Meri K. Tulic et al.   Nature Communications

The Emerging Epigenetic Role of CD8+T Cells in Autoimmune Diseases: A Systematic Review

(2019) Qiancheng Deng et al.   Frontiers in Immunology

Psychological disturbances in patients with pigmentary disorders: A cross‐sectional study

(2019) G. Dabas et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Learning From Success and Failure: Biologics for Non-approved Skin Diseases

(2019) Reinhart Speeckaert et al.   Frontiers in Immunology

Fas‐FasL interaction in cytotoxic T cell‐mediated vitiligo: The role of lesional expression of tumor necrosis factor‐α and interferon‐γ in Fas‐mediated melanocyte apoptosis

(2019) Haruki Jimbo et al.   EXPERIMENTAL DERMATOLOGY

Activated NLR family pyrin domain containing 3 (NLRP3) inflammasome in keratinocytes promotes cutaneous T-cell response in patients with vitiligo

(2019) Shuli Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Standardizing serial photography for assessing and monitoring vitiligo: a core set of international recommendations for essential clinical and technical specifications

(2019) Nanja van Geel et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Mitochondria as multifaceted regulators of cell death

(2019) Florian J. Bock et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti-CD20 therapy depletes activated myelin-specific CD8+T cells in multiple sclerosis

(2019) Joseph J. Sabatino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NKG2D Defines a Subset of Skin Effector Memory CD8 T Cells with Proinflammatory Functions in Vitiligo

(2019) Clément Jacquemin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

RNA-seq Reveals Dysregulation of Novel Melanocyte Genes upon Oxidative Stress: Implications in Vitiligo Pathogenesis

(2019) Konduru Seetharama Sastry et al.   Oxidative Medicine and Cellular Longevity

Automated scoring of vitiligo using superpixel-generated computerized digital image analysis of clinical photographs: a novel and consistent way to score vitiligo

(2018) J. J. H. Toh et al.   BRITISH JOURNAL OF DERMATOLOGY

Calcium signaling at the endoplasmic reticulum: fine-tuning stress responses

(2018) Amado Carreras-Sureda et al.   CELL CALCIUM

Regulatory T cells in autoimmune skin diseases

(2018) Hideyuki Ujiie   EXPERIMENTAL DERMATOLOGY

IL-17 induces cellular stress microenvironment of melanocytes to promote autophagic cell apoptosis in vitiligo

(2018) Jia Zhou et al.   FASEB JOURNAL

A Parametric Targetability Evaluation Approach for Vitiligo Proteome extracted through Integration of Gene Ontologies and Protein Interaction Topologies

(2018) Anvita Gupta Malhotra et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Innate Lymphoid Cells: Diversity, Plasticity, and Unique Functions in Immunity

(2018) Marco Colonna   IMMUNITY

HO-1 regulates the function of Treg: Association with the immune intolerance in vitiligo

(2018) Qian Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Vitiligo Skin Is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3

(2018) Katia Boniface et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HSP70I Q435A -Encoding DNA Repigments Vitiligo Lesions in Sinclair Swine

(2018) Steven W. Henning et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Critical appraisal of the oxidative stress pathway in vitiligo: a systematic review and meta-analysis

(2018) R. Speeckaert et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

(2018) Jillian M. Richmond et al.   Science Translational Medicine

Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents

(2018) Huimin Zou et al.   Frontiers in Immunology

Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells

(2018) Youdong Pan et al.   Frontiers in Immunology

Reference method for digital surface measurement of target lesions in vitiligo: a comparative analysis

(2018) N van Geel et al.   BRITISH JOURNAL OF DERMATOLOGY

TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress

(2018) Pan Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin D protects human melanocytes against oxidative damage by activation of Wnt/β-catenin signaling

(2018) Luyan Tang et al.   LABORATORY INVESTIGATION

PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin

(2018) Xiao Miao et al.   Scientific Reports

Genetic polymorphisms of GZMB and vitiligo: A genetic association study based on Chinese Han population

(2018) Meifeng Xu et al.   Scientific Reports

Molecular and cellular basis of depigmentation in vitiligo patients

(2018) Véronique Delmas et al.   EXPERIMENTAL DERMATOLOGY

Insights into the Role of ER Stress in Skin Function and Associated Diseases

(2018) Kyungho Park et al.   FEBS Journal

Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway

(2018) Jingjing Ma et al.   FREE RADICAL BIOLOGY AND MEDICINE

Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases

(2018) Tali Czarnowicki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

HMGB1 deficiency reduces H2 O2 -induced oxidative damage in human melanocytes via the Nrf2 pathway

(2018) Kuanhou Mou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Resident memory and recirculating memory T cells cooperate to maintain disease in a mouse model of vitiligo

(2018) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Innate immunosensing of DNA in cellular senescence

(2018) Selene Glück et al.   CURRENT OPINION IN IMMUNOLOGY

Oxeiptosis: a discreet way to respond to radicals

(2018) Pietro Scaturro et al.   CURRENT OPINION IN IMMUNOLOGY

Reduced Nrf2 activation in PI3K phosphorylation-impaired vitiliginous keratinocytes increases susceptibility to ROS-generating chemical-induced apoptosis

(2017) Hyangmi Kim et al.   ENVIRONMENTAL TOXICOLOGY

Melanocyte-protective effect of afzelin is mediated by the Nrf2-ARE signalling pathway via GSK-3β inactivation

(2017) Eunsun Jung et al.   EXPERIMENTAL DERMATOLOGY

Levels of oxidative damage and proinflammatory cytokines are enhanced in patients with active vitiligo

(2017) Sneha Mitra et al.   FREE RADICAL RESEARCH

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Regulatory T-cell cytokines in patients with nonsegmental vitiligo

(2017) Mehtap Kidir et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Vitiligo: Mechanistic insights lead to novel treatments

(2017) Michael L. Frisoli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Oxidative stress drives CD8 + T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes

(2017) Shuli Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Multiple Functional Variants of IFIH1 , a Gene Involved in Triggering Innate Immune Responses, Protect against Vitiligo

(2017) Ying Jin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and Progression

(2017) Ahmed F. Rezk et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MicroRNA-211 Regulates Oxidative Phosphorylation and Energy Metabolism in Human Vitiligo

(2017) Anupama Sahoo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Palladium and Platinum Nanoparticles Activate AHR and NRF2 in Human Keratinocytes—Implications in Vitiligo Therapy

(2017) Gaku Tsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Simvastatin Protects Human Melanocytes from H 2 O 2 -Induced Oxidative Stress by Activating Nrf2

(2017) Yuqian Chang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease

(2017) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CXCR3 Depleting Antibodies Prevent and Reverse Vitiligo in Mice

(2017) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Replenishing Regulatory T Cells to Halt Depigmentation in Vitiligo

(2017) I. Caroline Le Poole et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS

Development and in vitro assessment of psoralen and resveratrol co-loaded ultradeformable liposomes for the treatment of vitiligo

(2017) Sindhu Doppalapudi et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Local Inflammatory Cues Regulate Differentiation and Persistence of CD8 + Tissue-Resident Memory T Cells

(2017) Tessa Bergsbaken et al.   Cell Reports

Distinctive Surface Glycosylation Patterns Associated With Mouse and Human CD4+ Regulatory T Cells and Their Suppressive Function

(2017) Joana Cabral et al.   Frontiers in Immunology

Dysregulated autophagy increased melanocyte sensitivity to H2O2-induced oxidative stress in vitiligo

(2017) Yuanmin He et al.   Scientific Reports

Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin

(2017) Maria Lucia Dell’Anna et al.   Scientific Reports

Enhanced Th1 and Th17 responses in peripheral blood in active non-segmental vitiligo

(2016) Yu Zhen et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

The role of IL-17 in vitiligo: A review

(2016) Rasnik K. Singh et al.   AUTOIMMUNITY REVIEWS

Inhibition of skin inflammation by baicalin ultradeformable vesicles

(2016) Silvia Mir-Palomo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Aspirin induces Nrf2-mediated transcriptional activation of haem oxygenase-1 in protection of human melanocytes from H2O2-induced oxidative stress

(2016) Zhe Jian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Vitiligo: How do oxidative stress-induced autoantigens trigger autoimmunity?

(2016) Heng Xie et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming

(2016) Xiaoliang Wang et al.   JOURNAL OF IMMUNOLOGY

Novel insights into redox system and the mechanism of redox regulation

(2016) Xin Wang et al.   MOLECULAR BIOLOGY REPORTS

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

(2016) Ying Jin et al.   NATURE GENETICS

Innate lymphoid cell function in the context of adaptive immunity

(2016) Jennifer K Bando et al.   NATURE IMMUNOLOGY

Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

(2016) Jing He et al.   NATURE MEDICINE

Dysfunction of Autophagy: A Possible Mechanism Involved in the Pathogenesis of Vitiligo by Breaking the Redox Balance of Melanocytes

(2016) Zhuhui Qiao et al.   Oxidative Medicine and Cellular Longevity

Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression ofHLA-A*02:01in vivo

(2016) Masahiro Hayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1

(2016) Y. Wang et al.   SCIENCE

Interferon-gamma Inhibits Melanogenesis and Induces Apoptosis in Melanocytes: A Pivotal Role of CD8+ Cytotoxic T Lymphocytes in Vitiligo

(2015) L Yang et al.   ACTA DERMATO-VENEREOLOGICA

Alteration in regulatory T cells and programmed cell death 1-expressing regulatory T cells in active generalized vitiligo and their clinical correlation

(2015) M.K. Tembhre et al.   BRITISH JOURNAL OF DERMATOLOGY

Oxidative stress-induced overexpression of miR-25: the mechanism underlying the degeneration of melanocytes in vitiligo

(2015) Q Shi et al.   CELL DEATH AND DIFFERENTIATION

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

Cellular stress and innate inflammation in organ-specific autoimmunity: lessons learned from vitiligo

(2015) John E. Harris   IMMUNOLOGICAL REVIEWS

CCL22 to Activate Treg Migration and Suppress Depigmentation in Vitiligo

(2015) Jonathan M. Eby et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Altered E-Cadherin Levels and Distribution in Melanocytes Precede Clinical Manifestations of Vitiligo

(2015) Roselyne Y. Wagner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A pilot study to determine vitiligo target size using a computer-based image analysis program

(2015) Vaneeta M. Sheth et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Evaluation of serum trail level and DR4 gene variants as biomarkers for vitiligo patients

(2015) T. Edgunlu et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Increased circulating Th17 cells and elevated serum levels of TGF-beta and IL-21 are correlated with human non-segmental vitiligo development

(2015) Li Zhou et al.   Pigment Cell & Melanoma Research

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Resident memory T cells in human health and disease

(2015) R. A. Clark   Science Translational Medicine

Update on mesenchymal stem cell-based therapy in lupus and scleroderma

(2015) Audrey Cras et al.   ARTHRITIS RESEARCH & THERAPY

Vitiligo

(2015) Mauro Picardo et al.   Nature Reviews Disease Primers

Inflammasome activation and vitiligo/nonsegmental vitiligo progression

(2014) J. Marie et al.   BRITISH JOURNAL OF DERMATOLOGY

T helper 17 and Tregs: a novel proposed mechanism for NB-UVB in vitiligo

(2014) Rehab A. Hegazy et al.   EXPERIMENTAL DERMATOLOGY

Memory regulatory T cells reside in human skin

(2014) Robert Sanchez Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of oxidative stress in the pathogenesis of vitiligo with special emphasis on the antioxidant action of narrowband ultraviolet B phototherapy

(2014) Neslihan Karsli et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Melanocytes as Instigators and Victims of Oxidative Stress

(2014) Laurence Denat et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H 2 O 2 -Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo

(2014) Zhe Jian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Type I interferon signature in the initiation of the immune response in vitiligo

(2014) Antoine Bertolotti et al.   Pigment Cell & Melanoma Research

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of self-reactive CD8+T cells with an anergic phenotype in healthy individuals

(2014) Yuka Maeda et al.   SCIENCE

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo

(2014) M. Rashighi et al.   Science Translational Medicine

Effects of Low-Dose Recombinant Interleukin 2 to Promote T-Regulatory Cells in Alopecia Areata

(2014) Emeline Castela et al.   JAMA Dermatology

T helper and regulatory T cell cytokine profile in active, stable and narrow band ultraviolet B treated generalized vitiligo

(2013) Manoj Kumar Tembhre et al.   CLINICA CHIMICA ACTA

Stressing the cell cycle in senescence and aging

(2013) Hollie Chandler et al.   CURRENT OPINION IN CELL BIOLOGY

Innate immune mechanisms in vitiligo: danger from within

(2013) Jillian M Richmond et al.   CURRENT OPINION IN IMMUNOLOGY

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

Immunohistochemical analysis of FOXP3+ regulatory T cells in healthy human skin and autoimmune dermatoses

(2013) Sarah Terras et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Modern vitiligo genetics sheds new light on an ancient disease

(2013) Richard A. Spritz   JOURNAL OF DERMATOLOGY

Autophagy Is Induced by UVA and Promotes Removal of Oxidized Phospholipids and Protein Aggregates in Epidermal Keratinocytes

(2013) Yi Zhao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Oxidative Stress–Induced Calreticulin Expression and Translocation: New Insights into the Destruction of Melanocytes

(2013) Yajun Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo

(2013) Shilpak Chatterjee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Vitamin D Controls Murine and Human Plasmacytoid Dendritic Cell Function

(2013) Nina Karthaus et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

(2013) Ivan D Mascanfroni et al.   NATURE IMMUNOLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Vitiligo: A Possible Model of Degenerative Diseases

(2013) Barbara Bellei et al.   PLoS One

Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo

(2013) J. A. Mosenson et al.   Science Translational Medicine

CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer

(2013) L. Passerini et al.   Science Translational Medicine

Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial

(2013) Agnès Hartemann et al.   Lancet Diabetes & Endocrinology

Potential roles for CD8+ T cells in rheumatoid arthritis

(2012) Helena Carvalheiro et al.   AUTOIMMUNITY REVIEWS

Relationship of macrophage migration inhibitory factor levels in PBMCs, lesional skin and serum with disease severity and activity in vitiligo vulgaris

(2012) Lei Ma et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

Next-Generation DNA Re-Sequencing Identifies Common Variants of TYR and HLA-A that Modulate the Risk of Generalized Vitiligo via Antigen Presentation

(2012) Ying Jin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8+ T-Cell Accumulation in the Skin

(2012) John E. Harris et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

(2012) Hyun Choi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Circulatory levels of T-cell cytokines (interleukin [IL]-2, IL-4, IL-17, and transforming growth factor-?) in patients with vitiligo

(2012) Rehan Khan et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Digital image analysis vs. clinical assessment to evaluate repigmentation after punch grafting in vitiligo

(2012) M.W. Linthorst Homan et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

(2012) Ying Jin et al.   NATURE GENETICS

Systemic analyses of immunophenotypes of peripheral T cells in non-segmental vitiligo: implication of defective natural killer T cells

(2012) Li Zhou et al.   Pigment Cell & Melanoma Research

Global Activation of CD8+ Cytotoxic T Lymphocytes Correlates with an Impairment in Regulatory T Cells in Patients with Generalized Vitiligo

(2012) Yang Lili et al.   PLoS One

Computerised image analysis of vitiligo lesion: evaluation using manually defined lesion areas

(2012) Hermawan Nugroho et al.   SKIN RESEARCH AND TECHNOLOGY

Melanocytorrhagy and apoptosis in vitiligo: Connecting jigsaw pieces

(2011) Davinder Parsad et al.   Indian Journal of Dermatology Venereology & Leprology

Skin-Depigmenting Agent Monobenzone Induces Potent T-Cell Autoimmunity toward Pigmented Cells by Tyrosinase Haptenation and Melanosome Autophagy

(2011) Jasper G. van den Boorn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Heme Oxygenase-1 Protects Human Melanocytes from H2O2-Induced Oxidative Stress via the Nrf2-ARE Pathway

(2011) Zhe Jian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Six Decades of Vitiligo Genetics: Genome-Wide Studies Provide Insights into Autoimmune Pathogenesis

(2011) Richard A. Spritz   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis

(2011) David Saadoun et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dysregulation of melanocyte function by Th17-related cytokines: significance of Th17 cell infiltration in autoimmune vitiligo vulgaris

(2011) Yorihisa Kotobuki et al.   Pigment Cell & Melanoma Research

Th17 Cells and Activated Dendritic Cells Are Increased in Vitiligo Lesions

(2011) Claire Q. F. Wang et al.   PLoS One

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

(2011) S. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells: ultrastructural and immunophenotypical changes upon nb-UVB in vitiligo skin

(2010) Francesca Prignano et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Role of apoptosis and melanocytorrhagy: a comparative study of melanocyte adhesion in stable and unstable vitiligo

(2010) R. Kumar et al.   BRITISH JOURNAL OF DERMATOLOGY

Role of interleukin-17 in the pathogenesis of vitiligo

(2010) D. A. Bassiouny et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Involvement of Ca2+ and ROS in α-tocopheryl succinate-induced mitochondrial permeabilization

(2010) Vladimir Gogvadze et al.   INTERNATIONAL JOURNAL OF CANCER

Membrane lipid defects are responsible for the generation of reactive oxygen species in peripheral blood mononuclear cells from vitiligo patients

(2010) Maria Lucia Dell'Anna et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanisms of Spatial and Temporal Development of Autoimmune Vitiligo in Tyrosinase-Specific TCR Transgenic Mice

(2010) Randal K. Gregg et al.   JOURNAL OF IMMUNOLOGY

Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cells

(2010) Shelley Gorman et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Variant ofTYRand Autoimmunity Susceptibility Loci in Generalized Vitiligo

(2010) Ying Jin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced skin homing by functional Treg in vitiligo

(2010) Jared Klarquist et al.   Pigment Cell & Melanoma Research

Circulatory levels of antioxidants and lipid peroxidation in Indian patients with generalized and localized vitiligo

(2009) Rehan Khan et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

(2009) T Vanden Berghe et al.   CELL DEATH AND DIFFERENTIATION

Macrophage migration inhibitory factor in patients with vitiligo and relationship between duration and clinical type of disease

(2009) G. Serarslan et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Parthanatos, a messenger of death

(2009) Karen Kate David   Frontiers in Bioscience-Landmark

Major Role of Epidermal Growth Factor Receptor and Src Kinases in Promoting Oxidative Stress-dependent Loss of Adhesion and Apoptosis in Epithelial Cells

(2009) Hong-Lin Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

(2009) Jasper G. van den Boorn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

Functional Polymorphisms of the FAS Gene Associated with Risk of Vitiligo in Chinese Populations: A Case–Control Analysis

(2008) Miao Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HSP70i Accelerates Depigmentation in a Mouse Model of Autoimmune Vitiligo

(2008) Cecele J. Denman et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY