Journal
JOURNAL OF DERMATOLOGY
Volume 40, Issue 5, Pages 310-318Publisher
WILEY
DOI: 10.1111/1346-8138.12147
Keywords
autoimmune destruction; disease prevention; vitiligo; vitiligo genetics; vitiligo pathogenesis
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Funding
- National Institutes of Health [R01AR045584, R01AR056292, P30AR057212]
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Vitiligo is a complex disorder in which autoimmune destruction of melanocytes results in white patches of skin and overlying hair. Over the past several years, extensive genetic studies have outlined a biological framework of vitiligo pathobiology that underscores its relationship to other autoimmune diseases. This biological framework offers insight into both vitiligo pathogenesis and perhaps avenues towards more effective approaches to treatment and even disease prevention.
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