Update on mesenchymal stem cell-based therapy in lupus and scleroderma

Inhibition of B-Cell Proliferation and Antibody Production by Mesenchymal Stromal Cells Is Mediated by T Cells

(2015) Maria Manuela Rosado et al.   STEM CELLS AND DEVELOPMENT

Optimizing outcome in SLE: treating-to-target and definition of treatment goals

(2014) Andrea Doria et al.   AUTOIMMUNITY REVIEWS

Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis

(2014) Jacob M. van Laar et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Differential Efficacy of Human Mesenchymal Stem Cells Based on Source of Origin

(2014) Erin Collins et al.   JOURNAL OF IMMUNOLOGY

Umbilical cord mesenchymal stem cell transplantation in active and refractory systemic lupus erythematosus: a multicenter clinical study

(2014) Dandan Wang et al.   ARTHRITIS RESEARCH & THERAPY

Systematic Analysis of Donor and Isolation Factor's Impact on Human Islet Yield and Size Distribution

(2013) Y. Wang et al.   CELL TRANSPLANTATION

Allogenic Mesenchymal Stem Cell Transplantation Ameliorates Nephritis in Lupus Mice via Inhibition of B-Cell Activation

(2013) Xiaolei Ma et al.   CELL TRANSPLANTATION

Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy

(2013) P. Cipriani et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Rituximab in the treatment of resistant lupus nephritis: therapy failure in rapidly progressive crescentic lupus nephritis

(2013) RJ Davies et al.   LUPUS

Wnt/β-catenin signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients through the p53/p21 pathway

(2013) Zhifeng Gu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mesenchymal Stromal Cell Characteristics Vary Depending on Their Origin

(2013) Heike Wegmeyer et al.   STEM CELLS AND DEVELOPMENT

Expression of transforming growth factor β receptor II in mesenchymal stem cells from systemic sclerosis patients

(2013) Valérie Vanneaux et al.   BMJ Open

Mesenchymal SCT ameliorates refractory cytopenia in patients with systemic lupus erythematosus

(2012) X Li et al.   BONE MARROW TRANSPLANTATION

Upregulation of p16INK4A promotes cellular senescence of bone marrow-derived mesenchymal stem cells from systemic lupus erythematosus patients

(2012) Zhifeng Gu et al.   CELLULAR SIGNALLING

Gene Expression Profile Reveals Abnormalities of Multiple Signaling Pathways in Mesenchymal Stem Cell Derived from Patients with Systemic Lupus Erythematosus

(2012) Yu Tang et al.   Clinical & Developmental Immunology

Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice

(2012) Fei Gu et al.   CLINICAL IMMUNOLOGY

Allogeneic transplantation of umbilical cord-derived mesenchymal stem cells for diffuse alveolar hemorrhage in systemic lupus erythematosus

(2012) Dongyan Shi et al.   CLINICAL RHEUMATOLOGY

Enhanced Apoptosis and Senescence of Bone-Marrow-Derived Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus

(2012) Xia Li et al.   STEM CELLS AND DEVELOPMENT

Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells

(2012) Marius Strioga et al.   STEM CELLS AND DEVELOPMENT

Clinical prediction of 5-year survival in systemic sclerosis: validation of a simple prognostic model in EUSTAR centres

(2011) J. Fransen et al.   ANNALS OF THE RHEUMATIC DISEASES

Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation

(2011) Eun Wha Choi et al.   ARTHRITIS AND RHEUMATISM

Treatment of severe progressive systemic sclerosis with transplantation of mesenchymal stromal cells from allogeneic related donors: Report of five cases

(2011) Gernot Keyszer et al.   ARTHRITIS AND RHEUMATISM

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation

(2011) J A Snowden et al.   BONE MARROW TRANSPLANTATION

Interferon-γ-dependent inhibition of B cell activation by bone marrow-derived mesenchymal stem cells in a murine model of systemic lupus erythematosus

(2010) Francesca Schena et al.   ARTHRITIS AND RHEUMATISM

Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus

(2010) Lingyun Sun et al.   ARTHRITIS AND RHEUMATISM

Immunogenicity and Immunomodulatory Properties of Umbilical Cord Lining Mesenchymal Stem Cells

(2010) Tobias Deuse et al.   CELL TRANSPLANTATION

Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis

(2010) Jei-Wen Chang et al.   CELL TRANSPLANTATION

Transplantation of Human Bone Marrow Mesenchymal Stem Cell Ameliorates the Autoimmune Pathogenesis in MRL/lpr Mice

(2010) Kangxing Zhou et al.   Cellular & Molecular Immunology

Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice

(2010) Z. Gu et al.   LUPUS

Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus

(2010) Y. Nie et al.   LUPUS

Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury

(2009) Yuben Moodley et al.   AMERICAN JOURNAL OF PATHOLOGY

Animal models of scleroderma: lessons from transgenic and knockout mice

(2009) Emma C Derrett-Smith et al.   CURRENT OPINION IN RHEUMATOLOGY

Minimally cultured bone marrow mesenchymal stem cells ameliorate fibrotic lung injury

(2009) M. Kumamoto et al.   EUROPEAN RESPIRATORY JOURNAL

Adipose tissue-derived mesenchymal stem cells are more potent suppressors of dendritic cells differentiation compared to bone marrow-derived mesenchymal stem cells

(2009) Ekaterina Ivanova-Todorova et al.   IMMUNOLOGY LETTERS

Regulatory T Cell (Treg) Subsets Return in Patients with Refractory Lupus following Stem Cell Transplantation, and TGF- -Producing CD8+ Treg Cells Are Associated with Immunological Remission of Lupus

(2009) L. Zhang et al.   JOURNAL OF IMMUNOLOGY

Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse

(2009) A. Servettaz et al.   JOURNAL OF IMMUNOLOGY

Immunomodulatory Function of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Autoimmune Type 1 Diabetes

(2009) P. Fiorina et al.   JOURNAL OF IMMUNOLOGY

Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis

(2009) G. B. Appel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mesenchymal Stem Cell Transplantation Reverses Multiorgan Dysfunction in Systemic Lupus Erythematosus Mice and Humans

(2009) Lingyun Sun et al.   STEM CELLS

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

(2008) T. Alexander et al.   BLOOD

Mesenchymal stem cells from human bone marrow or adipose tissue differently modulate mitogen-stimulated B-cell immunoglobulin production in vitro

(2008) Ivan Bochev et al.   CELL BIOLOGY INTERNATIONAL

Therapeutic Effects of Bone Marrow-Derived Mesenchymal Stem Cells Engraftment on Bleomycin-Induced Lung Injury in Rats

(2008) F. Zhao et al.   TRANSPLANTATION PROCEEDINGS

Bone Marrow-Derived Mesenchymal Stem Cells Induce Both Polyclonal Expansion and Differentiation of B Cells Isolated from Healthy Donors and Systemic Lupus Erythematosus Patients

(2007) Elisabetta Traggiai et al.   STEM CELLS