Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants
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Title
Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants
Authors
Keywords
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Journal
NATURE GENETICS
Volume 48, Issue 11, Pages 1418-1424
Publisher
Springer Nature
Online
2016-10-11
DOI
10.1038/ng.3680
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Note: Only part of the references are listed.- Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression ofHLA-A*02:01in vivo
- (2016) Masahiro Hayashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo
- (2016) Giulio Cavalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Fan Liu et al. HUMAN GENETICS
- Allele-specific transcriptional regulation of IRF4 in melanocytes is mediated by chromatin looping of the intronic rs12203592 enhancer to the IRF4 promoter
- (2015) Mijke Visser et al. HUMAN MOLECULAR GENETICS
- Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases
- (2015) H. Guo et al. HUMAN MOLECULAR GENETICS
- Vitiligo-Like Depigmentation in Patients With Stage III-IV Melanoma Receiving Immunotherapy and Its Association With Survival: A Systematic Review and Meta-Analysis
- (2015) Hansje-Eva Teulings et al. JOURNAL OF CLINICAL ONCOLOGY
- Melanoma genetics
- (2015) Jazlyn Read et al. JOURNAL OF MEDICAL GENETICS
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- A gene-based association method for mapping traits using reference transcriptome data
- (2015) Eric R Gamazon et al. NATURE GENETICS
- PANTHER version 10: expanded protein families and functions, and analysis tools
- (2015) Huaiyu Mi et al. NUCLEIC ACIDS RESEARCH
- Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease
- (2015) Maria Wilbe et al. PLoS Genetics
- A Genome-Wide Association Study of Myasthenia Gravis
- (2015) Alan E. Renton et al. JAMA Neurology
- Re-Annotator: Annotation Pipeline for Microarray Probe Sequences
- (2015) Janine Arloth et al. PLoS One
- Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
- (2014) Alexander Gusev et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis
- (2014) Garima Juyal et al. GUT
- Markedly reduced incidence of melanoma and nonmelanoma skin cancer in a nonconcurrent cohort of 10,040 patients with vitiligo
- (2014) Andrea Paradisi et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Transcriptional enhancers: from properties to genome-wide predictions
- (2014) Daria Shlyueva et al. NATURE REVIEWS GENETICS
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Accounting for eXentricities: Analysis of the X Chromosome in GWAS Reveals X-Linked Genes Implicated in Autoimmune Diseases
- (2014) Diana Chang et al. PLoS One
- Defining functional DNA elements in the human genome
- (2014) M. Kellis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Enhancer variants: evaluating functions in common disease
- (2014) Olivia Corradin et al. Genome Medicine
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Mapping of Immune-Mediated Disease Genes
- (2013) Isis Ricaño-Ponce et al. Annual Review of Genomics and Human Genetics
- Functional interpretation of non-coding sequence variation: Concepts and challenges
- (2013) Dirk S. Paul et al. BIOESSAYS
- A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway
- (2013) Christian Praetorius et al. CELL
- Risk of Generalized Vitiligo Is Associated with the Common 55R-94A-247H Variant Haplotype of GZMB (Encoding Granzyme B)
- (2013) Tracey M. Ferrara et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23
- (2013) Yongzhe Li et al. NATURE GENETICS
- Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians
- (2012) Wanling Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Identification of a susceptibility locus inSTAT4for Behçet's disease in Han Chinese in a genome-wide association study
- (2012) Shengping Hou et al. ARTHRITIS AND RHEUMATISM
- Decreased risk of melanoma and nonmelanoma skin cancer in patients with vitiligo: a survey among 1307 patients and their partners
- (2012) H.E. Teulings et al. BRITISH JOURNAL OF DERMATOLOGY
- Next-Generation DNA Re-Sequencing Identifies Common Variants of TYR and HLA-A that Modulate the Risk of Generalized Vitiligo via Antigen Presentation
- (2012) Ying Jin et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
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- (2012) Young Ho Lee et al. MOLECULAR BIOLOGY REPORTS
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- (2012) Jonathan Shoag et al. MOLECULAR CELL
- Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo
- (2012) Ying Jin et al. NATURE GENETICS
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- (2012) Nicholas Eriksson et al. PLoS One
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- (2011) NATURE GENETICS
- g:Profiler—a web server for functional interpretation of gene lists (2011 update)
- (2011) Jüri Reimand et al. NUCLEIC ACIDS RESEARCH
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- (2011) Vincent Plagnol et al. PLoS Genetics
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- (2010) Sang Hong Lee et al. GENETIC EPIDEMIOLOGY
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- (2010) Lynn Petukhova et al. NATURE
- Common variants in FOXP1 are associated with generalized vitiligo
- (2010) Ying Jin et al. NATURE GENETICS
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- (2010) Patrick C A Dubois et al. NATURE GENETICS
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- Variant ofTYRand Autoimmunity Susceptibility Loci in Generalized Vitiligo
- (2010) Ying Jin et al. NEW ENGLAND JOURNAL OF MEDICINE
- The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma
- (2010) Richard A Spritz Genome Medicine
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- (2010) Dan L. Nicolae et al. PLoS Genetics
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