Resident memory T cells in human health and disease

Relapsing-Remitting Central Nervous System Autoimmunity Mediated by GFAP-Specific CD8 T Cells

(2014) K. Sasaki et al.   JOURNAL OF IMMUNOLOGY

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

(2014) S. Cheuk et al.   JOURNAL OF IMMUNOLOGY

Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials

(2014) Richard G. Langley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory

(2014) A. Okhrimenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 Pathway-Mediated Immunopathogenesis of Schizophrenia: Mechanisms and Implications

(2014) M. Debnath et al.   SCHIZOPHRENIA BULLETIN

Human TH9 Cells Are Skin-Tropic and Have Autocrine and Paracrine Proinflammatory Capacity

(2014) C. Schlapbach et al.   Science Translational Medicine

Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions

(2014) L. Maldonado et al.   Science Translational Medicine

Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites

(2013) S-W Tse et al.   GENES AND IMMUNITY

Lung-resident memory CD8 T cells (TRM ) are indispensable for optimal cross-protection against pulmonary virus infection

(2013) Tao Wu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ex vivoanalysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C

(2013) K. Yanagisawa et al.   JOURNAL OF VIRAL HEPATITIS

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

(2013) Jia Zhu et al.   NATURE

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Recirculating Memory T Cells Are a Unique Subset of CD4+ T Cells with a Distinct Phenotype and Migratory Pattern

(2012) S. K. Bromley et al.   JOURNAL OF IMMUNOLOGY

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

(2012) Xiaodong Jiang et al.   NATURE

T cell homing to epithelial barriers in allergic disease

(2012) Sabina A Islam et al.   NATURE MEDICINE

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

(2012) Jonathan P Sherlock et al.   NATURE MEDICINE

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients

(2012) R. A. Clark et al.   Science Translational Medicine

Immunologic characteristics of intrarenal T cells: Trafficking of expanded CD8+ T cell β-chain clonotypes in progressive lupus nephritis

(2011) Robert Winchester et al.   ARTHRITIS AND RHEUMATISM

CD8+ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung

(2011) Berber Piet et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Characterization of a Human Cervical CD4+ T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility

(2011) L. R. McKinnon et al.   JOURNAL OF IMMUNOLOGY

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

(2011) Thomas Gebhardt et al.   NATURE

Resident Memory T Cells (TRM) Are Abundant in Human Lung: Diversity, Function, and Antigen Specificity

(2011) Rahul Purwar et al.   PLoS One

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

(2011) William R. Swindell et al.   PLoS One

Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

(2010) J. J. Campbell et al.   BLOOD

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Papillomavirus 16-Associated Cervical Intraepithelial Neoplasia in Humans Excludes CD8 T Cells from Dysplastic Epithelium

(2010) C. L. Trimble et al.   JOURNAL OF IMMUNOLOGY

Resolved Psoriasis Lesions Retain Expression of a Subset of Disease-Related Genes

(2010) Mayte Suárez-Fariñas et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epidermal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell–mediated immunity

(2010) Luzheng Liu et al.   NATURE MEDICINE

Skin-Resident T Cells: The Ups and Downs of On Site Immunity

(2009) Rachael A. Clark   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Functional Effector Memory T Cells Enrich the Peritoneal Cavity of Patients Treated with Peritoneal Dialysis

(2009) G. W. Roberts et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome

(2008) R. van Doorn et al.   BLOOD

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

(2008) L. M. Wakim et al.   SCIENCE