Local heroes or villains: tissue-resident memory T cells in human health and disease

Memory T Cell Dynamics in the Lung during Influenza Virus Infection

(2019) Angela Pizzolla et al.   JOURNAL OF IMMUNOLOGY

Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation

(2019) Sebastian Zundler et al.   NATURE IMMUNOLOGY

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

(2019) Marios Koutsakos et al.   NATURE IMMUNOLOGY

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses

(2019) Lalit K. Beura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-Resident T Cells and Other Resident Leukocytes

(2019) David Masopust et al.   Annual Review of Immunology

Early primed KLRG1- CMV-specific T cells determine the size of the inflationary T cell pool

(2019) Nicolas S. Baumann et al.   PLoS Pathogens

Heterogeneity and fate choice: T cell exhaustion in cancer and chronic infections

(2019) Mary Philip et al.   CURRENT OPINION IN IMMUNOLOGY

High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity

(2019) Natasja L de Vries et al.   GUT

Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer

(2019) James Clarke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resident memory CD8 T cells persist for years in human small intestine

(2019) Raquel Bartolomé-Casado et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular and histopathology directed therapy for advanced bladder cancer

(2019) Constantine Alifrangis et al.   Nature Reviews Urology

Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

(2019) Maria Carolina Amezcua Vesely et al.   CELL

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality

(2019) Chaofan Li et al.   IMMUNITY

Tissue-Resident Memory T Cells in Cancer Immunosurveillance

(2019) Simone L. Park et al.   TRENDS IN IMMUNOLOGY

The Global Landscape of EBV-Associated Tumors

(2019) Claire Shannon-Lowe et al.   Frontiers in Oncology

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells

(2018) Joana Machado-Santos et al.   BRAIN

Tissue-resident memory T cells are epigenetically cytotoxic with signs of exhaustion in human urinary bladder cancer

(2018) Ciputra Adijaya Hartana et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD103+Tumor-Resident CD8+T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti–PD-1 Treatment

(2018) Jarem Edwards et al.   CLINICAL CANCER RESEARCH

Tissue-Specific Control of Tissue-Resident Memory T Cells

(2018) Yong Liu et al.   CRITICAL REVIEWS IN IMMUNOLOGY

The (gradual) rise of memory inflation

(2018) Paul Klenerman   IMMUNOLOGICAL REVIEWS

Clinical and Molecular Aspects of Vitiligo Treatments

(2018) Anuradha Bishnoi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles

(2018) Angela Pizzolla et al.   JOURNAL OF CLINICAL INVESTIGATION

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

(2018) Lalit K. Beura et al.   NATURE IMMUNOLOGY

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

(2018) Simone L. Park et al.   NATURE IMMUNOLOGY

Tissue-resident memory T cells at the center of immunity to solid tumors

(2018) Derk Amsen et al.   NATURE IMMUNOLOGY

Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

(2018) Peter Savas et al.   NATURE MEDICINE

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

(2018) Jillian M. Richmond et al.   Science Translational Medicine

Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors

(2018) Thomas Duhen et al.   Nature Communications

Induction and Maintenance of CX3CR1-Intermediate Peripheral Memory CD8 + T Cells by Persistent Viruses and Vaccines

(2018) Claire Louse Gordon et al.   Cell Reports

Tissue maintenance of CMV-specific inflationary memory T cells by IL-15

(2018) Nicolas S. Baumann et al.   PLoS Pathogens

A Systematic Review: The Role of Resident Memory T Cells in Infectious Diseases and Their Relevance for Vaccine Development

(2018) Visai Muruganandah et al.   Frontiers in Immunology

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

(2018) David J. Topham et al.   Frontiers in Immunology

Role of Tissue-Resident Memory in Intra-Tumor Heterogeneity and Response to Immune Checkpoint Blockade

(2018) Kavita M. Dhodapkar   Frontiers in Immunology

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection

(2018) Sneha Sant et al.   Frontiers in Immunology

Vaccination-induced skin-resident memory CD8+ T cells mediate strong protection against cutaneous melanoma

(2018) Felipe Gálvez-Cancino et al.   OncoImmunology

A Fixed Spatial Structure of CD8+T Cells in Tissue during Chronic HSV-2 Infection

(2018) Joshua T. Schiffer et al.   JOURNAL OF IMMUNOLOGY

Transplantation of Tissue-Resident Lymphocytes

(2018) Amy Prosser et al.   TRANSPLANTATION

Memory Inflation Drives Tissue-Resident Memory CD8+ T Cell Maintenance in the Lung After Intranasal Vaccination With Murine Cytomegalovirus

(2018) Kaitlyn M. Morabito et al.   Frontiers in Immunology

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

(2018) Bagher Farhood et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin

(2018) Simone L. Park et al.   NATURE

Tissue Resident CD8 Memory T Cell Responses in Cancer and Autoimmunity

(2018) Aleksey Molodtsov et al.   Frontiers in Immunology

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Psoriasis pathogenesis and the development of novel targeted immune therapies

(2017) Jason E. Hawkes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing αβ T cell clones

(2017) Tiago R. Matos et al.   JOURNAL OF CLINICAL INVESTIGATION

Long-lived tissue resident HIV-1 specific memory CD8 + T cells are generated by skin immunization with live virus vectored microneedle arrays

(2017) Marija Zaric et al.   JOURNAL OF CONTROLLED RELEASE

IL-2hightissue-resident T cells in the human liver: Sentinels for hepatotropic infection

(2017) Laura J. Pallett et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection

(2017) Claire L. Gordon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103−CD8+ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium

(2017) Anna Gibbs et al.   JOURNAL OF INFECTIOUS DISEASES

CpG in Combination with an Inhibitor of Notch Signaling Suppresses Formalin-Inactivated Respiratory Syncytial Virus-Enhanced Airway Hyperresponsiveness and Inflammation by Inhibiting Th17 Memory Responses and Promoting Tissue-Resident Memory Cells in Lungs

(2017) Lei Zhang et al.   JOURNAL OF VIROLOGY

Airway T cells protect against RSV infection in the absence of antibody

(2017) E Kinnear et al.   Mucosal Immunology

Induction of vaginal-resident HIV-specific CD8 T cells with mucosal prime–boost immunization

(2017) H-X Tan et al.   Mucosal Immunology

Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection

(2017) Brenna E Kiniry et al.   Mucosal Immunology

Enrichment of herpes simplex virus type 2 (HSV-2) reactive mucosal T cells in the human female genital tract

(2017) C M Posavad et al.   Mucosal Immunology

Trigger-happy resident memory CD4+ T cells inhabit the human lungs

(2017) A E Oja et al.   Mucosal Immunology

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

(2017) J. Justin Milner et al.   NATURE

Respiratory syncytial virus elicits enriched CD8+ T lymphocyte responses in lung compared with blood in African green monkeys

(2017) Hualin Li et al.   PLoS One

Transcriptional Regulation of Tissue-Resident Lymphocytes

(2017) Laura K. Mackay et al.   TRENDS IN IMMUNOLOGY

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Treatment of Alopecia Areata With Tofacitinib

(2017) Omer Ibrahim et al.   JAMA Dermatology

Epidemiology and Molecular Biology of Head and Neck Cancer

(2017) Adriana Jou et al.   Oncology Research and Treatment

CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer

(2017) Fenne L. Komdeur et al.   OncoImmunology

Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity

(2017) Femke Stelma et al.   Scientific Reports

CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma

(2016) Hagma H. Workel et al.   EUROPEAN JOURNAL OF CANCER

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

(2016) Daniel Fernandez-Ruiz et al.   IMMUNITY

Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma

(2016) Brian D. Hondowicz et al.   IMMUNITY

Combined Immunoscore of CD103 and CD3 Identifies Long-Term Survivors in High-Grade Serous Ovarian Cancer

(2016) Hans-Christian Bösmüller et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

TGF-β Controls the Formation of Kidney-Resident T Cells via Promoting Effector T Cell Extravasation

(2016) Chaoyu Ma et al.   JOURNAL OF IMMUNOLOGY

IL-15–Independent Maintenance of Tissue-Resident and Boosted Effector Memory CD8 T Cells

(2016) Jason M. Schenkel et al.   JOURNAL OF IMMUNOLOGY

Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair Loss

(2016) Jane Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung

(2016) K M Morabito et al.   Mucosal Immunology

Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

(2016) Pleun Hombrink et al.   NATURE IMMUNOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

(2016) Nicholas Collins et al.   Nature Communications

Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

(2016) Sama Adnan et al.   PLoS Pathogens

Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs

(2016) Heng Giap Woon et al.   PLoS Pathogens

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus

(2015) Maximillian S. Habibi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

CD8+CD103+Tumor–Infiltrating Lymphocytes Are Tumor-Specific Tissue-Resident Memory T Cells and a Prognostic Factor for Survival in Lung Cancer Patients

(2015) Fayçal Djenidi et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention

(2015) Laura K. Mackay et al.   JOURNAL OF IMMUNOLOGY

CD103+ Tumor Infiltrating Lymphocytes Predict a Favorable Prognosis in Urothelial Cell Carcinoma of the Bladder

(2015) Bo Wang et al.   JOURNAL OF UROLOGY

CD161intCD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut

(2015) J R Fergusson et al.   Mucosal Immunology

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

(2015) Shruti Naik et al.   NATURE

Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8+ T cells responding to infection

(2015) Tessa Bergsbaken et al.   NATURE IMMUNOLOGY

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Resident memory T cells in human health and disease

(2015) R. A. Clark   Science Translational Medicine

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

(2015) Agnieszka Jozwik et al.   Nature Communications

The Salivary Gland Acts as a Sink for Tissue-Resident Memory CD8 + T Cells, Facilitating Protection from Local Cytomegalovirus Infection

(2015) Jenny Tosca Thom et al.   Cell Reports

Murine CMV Infection Induces the Continuous Production of Mucosal Resident T Cells

(2015) Corinne J. Smith et al.   Cell Reports

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

(2014) Brian S. Sheridan et al.   IMMUNITY

Tissue-resident T cells,in situimmunity and transplantation

(2014) Damian L. Turner et al.   IMMUNOLOGICAL REVIEWS

Memory regulatory T cells reside in human skin

(2014) Robert Sanchez Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Local Recall Responses by Memory T Cells Newly Recruited to Peripheral Nonlymphoid Tissues

(2014) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

(2014) S. Cheuk et al.   JOURNAL OF IMMUNOLOGY

The IL-17A-Producing CD8 + T-Cell Population in Psoriatic Lesional Skin Comprises Mucosa-Associated Invariant T Cells and Conventional T Cells

(2014) Marcel B.M. Teunissen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Clonal Evolution of CD8+T Cell Responses against Latent Viruses: Relationship among Phenotype, Localization, and Function

(2014) Ester B. M. Remmerswaal et al.   JOURNAL OF VIROLOGY

Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury

(2014) Christine Guo Lian et al.   MODERN PATHOLOGY

Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

(2014) Luzhou Xing et al.   NATURE MEDICINE

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Location, location, location

(2014) John R Webb et al.   OncoImmunology

CMV: Prevention, Diagnosis and Therapy

(2013) C. N. Kotton   AMERICAN JOURNAL OF TRANSPLANTATION

Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

(2013) Nu Zhang et al.   IMMUNITY

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

T cells in the human metastatic melanoma microenvironment express site-specific homing receptors and retention integrins

(2013) Elise P. Salerno et al.   INTERNATIONAL JOURNAL OF CANCER

Evaluation of the Humoral and Cellular Immune Responses Elicited by the Live Attenuated and Inactivated Influenza Vaccines and Their Roles in Heterologous Protection in Ferrets

(2013) Xing Cheng et al.   JOURNAL OF INFECTIOUS DISEASES

Viral Shedding and Immune Responses to Respiratory Syncytial Virus Infection in Older Adults

(2013) Edward E. Walsh et al.   JOURNAL OF INFECTIOUS DISEASES

Lung-resident memory CD8 T cells (TRM ) are indispensable for optimal cross-protection against pulmonary virus infection

(2013) Tao Wu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Cold-adapted X-31 live attenuated 2009 pandemic H1N1 influenza vaccine elicits protective immune responses in mice and ferrets

(2013) Yo Han Jang et al.   VACCINE

High-Quality CMV-Specific CD4+Memory Is Enriched in the Lung Allograft and Is Associated With Mucosal Viral Control

(2012) J. A. Akulian et al.   AMERICAN JOURNAL OF TRANSPLANTATION

PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

(2012) C. Badoual et al.   CANCER RESEARCH

CD103 or LFA-1 Engagement at the Immune Synapse between Cytotoxic T Cells and Tumor Cells Promotes Maturation and Regulates T-cell Effector Functions

(2012) K. Franciszkiewicz et al.   CANCER RESEARCH

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Cutting Edge: Intravascular Staining Redefines Lung CD8 T Cell Responses

(2012) K. G. Anderson et al.   JOURNAL OF IMMUNOLOGY

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

(2012) Xiaodong Jiang et al.   NATURE

Alopecia Areata

(2012) Amos Gilhar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients

(2012) R. A. Clark et al.   Science Translational Medicine

Human virus-specific effector-type T cells accumulate in blood but not in lymph nodes

(2011) E. B. M. Remmerswaal et al.   BLOOD

CD8+ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung

(2011) Berber Piet et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

E-cadherin promotes accumulation of a unique memory CD8 T-cell population in murine salivary glands

(2011) M. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+ T cells clear virus but augment disease in mice infected with respiratory syncytial virus. Comparison with the effects of CD8+ T cells

(2010) W. H. ALWAN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Profound elevation of CD8+ T cells expressing the intraepithelial lymphocyte marker CD103 (αE/β7 Integrin) in high-grade serous ovarian cancer

(2010) John R. Webb et al.   GYNECOLOGIC ONCOLOGY

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epidermal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell–mediated immunity

(2010) Luzheng Liu et al.   NATURE MEDICINE

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

(2009) Melanie A. Kleinschek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow

(2008) U. Palendira et al.   BLOOD

Rapidly Cleared Episodes of Herpes Simplex Virus Reactivation in Immunocompetent Adults

(2008) Karen E. Mark et al.   JOURNAL OF INFECTIOUS DISEASES

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE