RNA-Binding Proteins as Regulators of Migration, Invasion and Metastasis in Oral Squamous Cell Carcinoma

MiRNAs and LncRNAs: Dual Roles in TGF-β Signaling-Regulated Metastasis in Lung Cancer

(2020) Xing-Ning Lai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs

(2020) Marina K. Kukhanova et al.   MOLECULES

Global patterns and trends in cancers of the lip, tongue and mouth

(2020) Adalberto Miranda-Filho et al.   ORAL ONCOLOGY

Understanding and targeting the disease‐related RNA binding protein human antigen R (HuR)

(2020) Christopher W. Schultz et al.   Wiley Interdisciplinary Reviews-RNA

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

(2020) Huilin Huang et al.   CANCER CELL

Small‐Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer

(2020) Rajiv K. Bedi et al.   ChemMedChem

RNA-Binding Proteins as Important Regulators of Long Non-Coding RNAs in Cancer

(2020) Katharina Jonas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA-Targeted Therapies and High-Throughput Screening Methods

(2020) Siran Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA-Binding Proteins in Acute Leukemias

(2020) Konstantin Schuschel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA-Binding Proteins in Pulmonary Hypertension

(2020) Hui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Context specificity of the EMT transcriptional response

(2020) David P. Cook et al.   Nature Communications

LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity

(2020) Agnes Dorn et al.   Cancers

M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT

(2020) Guang-Zhao Huang et al.   Aging-US

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

(2020) Lindsay M. LaFave et al.   CANCER CELL

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

(2020) Nemanja Despot Marjanovic et al.   CANCER CELL

Alternative splicing and cancer: insights, opportunities, and challenges from an expanding view of the transcriptome

(2020) Sara Cherry et al.   GENES & DEVELOPMENT

Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma

(2020) Jessica L. Bell et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Potential Contribution of Dysfunctional RNA-Binding Proteins to the Pathogenesis of Neurodegeneration in Multiple Sclerosis and Relevant Models

(2020) Cole D. Libner et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA Binding Proteins as Drivers and Therapeutic Target Candidates in Pancreatic Ductal Adenocarcinoma

(2020) Markus Glaß et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

METTL3 Promotes Tumorigenesis and Metastasis through BMI1 m6A Methylation in Oral Squamous Cell Carcinoma

(2020) Lin Liu et al.   MOLECULAR THERAPY

The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer

(2020) Simon Müller et al.   NUCLEIC ACIDS RESEARCH

METTL3 Facilitates Oral Squamous Cell Carcinoma Tumorigenesis by Enhancing c-Myc Stability via YTHDF1-Mediated m6A Modification

(2020) Wei Zhao et al.   Molecular Therapy-Nucleic Acids

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

(2019) Nina Ripin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma

(2019) Cristina Porcheri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA binding proteins in hematopoiesis and hematological malignancy

(2019) Daniel J. Hodson et al.   BLOOD

Defining the Hallmarks of Metastasis

(2019) Danny R. Welch et al.   CANCER RESEARCH

Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis

(2019) Wei Lu et al.   DEVELOPMENTAL CELL

QKI, a miR‐200 target gene, suppresses epithelial‐to‐mesenchymal transition and tumor growth

(2019) Eun Ju Kim et al.   INTERNATIONAL JOURNAL OF CANCER

Knockdown of MSI1 inhibits the proliferation of human oral squamous cell carcinoma by inactivating STAT3 signaling

(2019) Chen‑Fei Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Gain of Additional BIRC3 Protein Functions through 3ʹ-UTR-Mediated Protein Complex Formation

(2019) Shih-Han Lee et al.   MOLECULAR CELL

R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation

(2019) Maiwen Caudron-Herger et al.   MOLECULAR CELL

N6-methyladenosine modifications: interactions with novel RNA-binding proteins and roles in signal transduction

(2019) Jiaxin Chen et al.   RNA Biology

ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation

(2019) Xue Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cancer the‘RBP’eutics–RNA-binding proteins as therapeutic targets for cancer

(2019) Shakur Mohibi et al.   PHARMACOLOGY & THERAPEUTICS

Clinical update on head and neck cancer: molecular biology and ongoing challenges

(2019) Elham Alsahafi et al.   Cell Death & Disease

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

(2019) Gerard Minuesa et al.   Nature Communications

Splicing factor derived circular RNA circUHRF1 accelerates oral squamous cell carcinoma tumorigenesis via feedback loop

(2019) Wei Zhao et al.   CELL DEATH AND DIFFERENTIATION

Degradation of splicing factor SRSF3 contributes to progressive liver disease

(2019) Deepak Kumar et al.   JOURNAL OF CLINICAL INVESTIGATION

Reading, writing and erasing mRNA methylation

(2019) Sara Zaccara et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identifying chemogenetic interactions from CRISPR screens with drugZ

(2019) Medina Colic et al.   Genome Medicine

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis

(2019) Bruno Di Stefano et al.   Cell Stem Cell

Discovery of Small‐Molecule Modulators of Protein–RNA Interactions by Fluorescence Intensity‐Based Binding Assay

(2019) Wan Gi Byun et al.   CHEMBIOCHEM

Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution

(2019) Jernej Ule et al.   MOLECULAR CELL

LIN28: A cancer stem cell promoter for immunotherapy in head and neck squamous cell carcinoma

(2019) Mengxue Li et al.   ORAL ONCOLOGY

DDX3 activates CBC-eIF3-mediated translation of uORF-containing oncogenic mRNAs to promote metastasis in HNSCC

(2018) Hung-Hsi Chen et al.   CANCER RESEARCH

RNA-Targeted Therapeutics

(2018) Stanley T. Crooke et al.   Cell Metabolism

Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 is a Novel Post-Transcriptional Regulator of Ewing Sarcoma Malignancy

(2018) Caterina Mancarella et al.   CLINICAL CANCER RESEARCH

Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels

(2018) Julia K. Nussbacher et al.   MOLECULAR CELL

Dual gene activation and knockout screen reveals directional dependencies in genetic networks

(2018) Michael Boettcher et al.   NATURE BIOTECHNOLOGY

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability

(2018) Wang Lai Hu et al.   NATURE CELL BIOLOGY

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

(2018) Huilin Huang et al.   NATURE CELL BIOLOGY

RNA-binding proteins control gene expression and cell fate in the immune system

(2018) Martin Turner et al.   NATURE IMMUNOLOGY

A brave new world of RNA-binding proteins

(2018) Matthias W. Hentze et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors

(2018) Simon Müller et al.   NUCLEIC ACIDS RESEARCH

ADARs and editing: The role of A-to-I RNA modification in cancer progression

(2018) Kajsa Fritzell et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7–Lin28 RNA–Protein Interaction

(2018) Daniel A. Lorenz et al.   ACS Medicinal Chemistry Letters

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28

(2018) Longfei Wang et al.   Cell Reports

Gossypol Inhibits Non-small Cell Lung Cancer Cells Proliferation by Targeting EGFRL858R/T790M

(2018) Yuwei Wang et al.   Frontiers in Pharmacology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts

(2018) Sihyung Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling

(2018) Ayala Shiber et al.   NATURE

Protein complexes assemble as they are being made

(2018) Christine Mayr   NATURE

Structural and functional characterization of hMEX-3C Ring finger domain as an E3 ubiquitin ligase

(2018) Sayed Ala Moududee et al.   PROTEIN SCIENCE

What Are 3′ UTRs Doing?

(2018) Christine Mayr   Cold Spring Harbor Perspectives in Biology

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest

(2018) Jakob Trendel et al.   CELL

Cyclooxygenase-2 in cancer: A review

(2018) Nasser Hashemi Goradel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Overexpression of ADAR 1 into the cytoplasm correlates with a better prognosis of patients with oral squamous cells carcinoma

(2018) Vito Carlo Alberto Caponio et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

RNA-binding proteins in neurodegeneration: mechanisms in aggregate

(2017) Erin G. Conlon et al.   GENES & DEVELOPMENT

The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting

(2017) Lishi Li et al.   GENOME RESEARCH

Distant metastases in head and neck cancer

(2017) Fréderic Duprez et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The Dark Side of the Epitranscriptome: Chemical Modifications in Long Non-Coding RNAs

(2017) Roland Jacob et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition

(2017) Kamaleldin E. Elagib et al.   JOURNAL OF CLINICAL INVESTIGATION

Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development

(2017) Weidan Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression

(2017) Davide Pradella et al.   Molecular Cancer

Alternative splicing as a regulator of development and tissue identity

(2017) Francisco E. Baralle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro

(2017) Kawaljit Kaur et al.   PLoS One

A Small-Molecule Inhibitor of Lin28

(2016) Martina Roos et al.   ACS Chemical Biology

Insulin-like growth factor-II mRNA binding protein-3 and podoplanin expression are associated with bone invasion and prognosis in oral squamous cell carcinoma

(2016) Young Sun Hwang et al.   ARCHIVES OF ORAL BIOLOGY

Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment

(2016) Lubing Gu et al.   CANCER CELL

RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3

(2016) Min Xie et al.   CANCER RESEARCH

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

The new (dis)order in RNA regulation

(2016) Aino I. Järvelin et al.   Cell Communication and Signaling

The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer

(2016) Zhongwei Li et al.   CELL DEATH AND DIFFERENTIATION

A common framework for EMT and collective cell migration

(2016) Kyra Campbell et al.   DEVELOPMENT

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

(2016) Sonam Dhamija et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of SRSF3 is Correlated with Carcinogenesis and Progression of Oral Squamous Cell Carcinoma

(2016) Liu Peiqi et al.   International Journal of Medical Sciences

Laminin-5 and insulin-like growth factor-II mRNA binding protein-3 (IMP3) expression in preoperative biopsy specimens from oral cancer patients: Their role in neural spread risk and survival stratification

(2016) Achille Tarsitano et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

DDX3 Modulates Neurite Development via Translationally Activating an RNA Regulon Involved in Rac1 Activation

(2016) H.-H. Chen et al.   JOURNAL OF NEUROSCIENCE

Discovery of a Small-Molecule Inhibitor of Protein–MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28

(2016) Donghyun Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Notch1 signaling contributes to stemness in head and neck squamous cell carcinoma

(2016) Sang H Lee et al.   LABORATORY INVESTIGATION

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes

(2016) Kristopher W. Brannan et al.   MOLECULAR CELL

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

An inducible long noncoding RNA amplifies DNA damage signaling

(2016) Adam M Schmitt et al.   NATURE GENETICS

Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

(2016) Duncan E. Scott et al.   NATURE REVIEWS DRUG DISCOVERY

A comprehensive map of molecular drug targets

(2016) Rita Santos et al.   NATURE REVIEWS DRUG DISCOVERY

The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family

(2016) Bianca Busch et al.   NUCLEIC ACIDS RESEARCH

Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing

(2016) Helen L. Lightfoot et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq

(2016) Cindo O. Nicholson et al.   RNA

Posttranslational control of HuR function

(2016) Ioannis Grammatikakis et al.   Wiley Interdisciplinary Reviews-RNA

Structural insights into the molecular mechanism of the m6A writer complex

(2016) Paweł Śledź et al.   eLife

HnRNP L is important for the expression of oncogene SRSF3 and oncogenic potential of oral squamous cell carcinoma cells

(2016) Rong Jia et al.   Scientific Reports

Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction

(2015) Xiaoqing Wu et al.   ACS Chemical Biology

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

The pluripotency factor LIN28B is involved in oral carcinogenesis and associates with tumor aggressiveness and unfavorable prognosis

(2015) Dongmiao Wang et al.   Cancer Cell International

Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State

(2015) C.-S. Chien et al.   CANCER RESEARCH

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy

(2015) G. M. Bol et al.   EMBO Molecular Medicine

Prognostic impact of perineural invasion and lymphovascular invasion in advanced stage oral squamous cell carcinoma

(2015) J.F. Jardim et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Elevated Lin28B expression is correlated with lymph node metastasis in oral squamous cell carcinomas

(2015) Wei-Tung Lin et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Phenotypic plasticity and epithelial-to-mesenchymal transition in the behaviour and therapeutic response of oral squamous cell carcinoma

(2015) Navin Vig et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Evaluation of Lymphatic and Vascular Invasion in Relation to Clinicopathological Factors and Treatment Outcome in Oral Cavity Squamous Cell Carcinoma

(2015) Mohamad Adel et al.   MEDICINE

DDX3, a potential target for cancer treatment

(2015) Guus Martinus Bol et al.   Molecular Cancer

Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1

(2015) Lan Lan et al.   Molecular Oncology

Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization

(2015) Binyamin D. Berkovits et al.   NATURE

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation

(2015) Johannes Popow et al.   RNA

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins

(2015) Alfredo Castello et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

EGF enhances low-invasive cancer cell invasion by promoting IMP-3 expression

(2015) Xianglan Zhang et al.   TUMOR BIOLOGY

NZ51, a ring-expanded nucleoside analog, inhibits motility and viability of breast cancer cells by targeting the RNA helicase DDX3

(2015) Min Xie et al.   Oncotarget

An isocorydine derivative (d-ICD) inhibits drug resistance by downregulating IGF2BP3 expression in hepatocellular carcinoma

(2015) Meng Li et al.   Oncotarget

Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer

(2015) Sabindra K. Samal et al.   Scientific Reports

Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function

(2015) Vito Giuseppe D’Agostino et al.   Scientific Reports

Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

(2015) Zhonghua Wang et al.   PLoS One

High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells

(2014) Michael Boettcher et al.   BMC GENOMICS

QKI impairs self-renewal and tumorigenicity of oral cancer cells via repression of SOX2

(2014) Wei Lu et al.   CANCER BIOLOGY & THERAPY

Prognostic significance of neural stem cell markers, Nestin and Musashi-1, in oral squamous cell carcinoma: expression pattern of Nestin in the precancerous stages of oral squamous epithelium

(2014) Gokulan Ravindran et al.   Clinical Oral Investigations

A 1536-Well Fluorescence Polarization Assay to Screen for Modulators of the MUSASHI Family of RNA-Binding Proteins

(2014) Gerard Minuesa et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma

(2014) Tony Gutschner et al.   HEPATOLOGY

Epithelial Splicing Regulatory Proteins 1 (ESRP1) and 2 (ESRP2) Suppress Cancer Cell Motility via Different Mechanisms

(2014) Hiroki Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dynamic RNA Modifications in Posttranscriptional Regulation

(2014) Xiao Wang et al.   MOLECULAR CELL

Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity

(2014) Hao Huang et al.   MOLECULAR CELL

Emerging biomarkers in head and neck cancer in the era of genomics

(2014) Hyunseok Kang et al.   Nature Reviews Clinical Oncology

A census of human RNA-binding proteins

(2014) Stefanie Gerstberger et al.   NATURE REVIEWS GENETICS

The structure, function and evolution of proteins that bind DNA and RNA

(2014) William H. Hudson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway

(2014) H-H Chen et al.   ONCOGENE

HuD Promotes Progression of Oral Squamous Cell Carcinoma

(2014) Tomonori Sasahira et al.   PATHOBIOLOGY

ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis

(2014) Sung-Hee Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer

(2014) Marcell Lederer et al.   SEMINARS IN CANCER BIOLOGY

A recently evolved class of alternative 3′-terminal exons involved in cell cycle regulation by topoisomerase inhibitors

(2014) Martin Dutertre et al.   Nature Communications

RNA-binding proteins regulate the expression of the immune activating ligand MICB

(2014) Daphna Nachmani et al.   Nature Communications

Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite

(2014) Carina C Clingman et al.   eLife

Dissecting the expression landscape of RNA-binding proteins in human cancers

(2014) Bobak Kechavarzi et al.   GENOME BIOLOGY

Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection

(2014) Yasuo Ariumi   Frontiers in Genetics

Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains

(2013) Kristin Wächter et al.   BIOLOGICAL CHEMISTRY

Basal stem cells contribute to squamous cell carcinomas in the oral cavity

(2013) Xiao-Han Tang et al.   CARCINOGENESIS

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition

(2013) Luis A. Aparicio et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)

(2013) Monika Hämmerle et al.   HEPATOLOGY

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

The RNA-binding protein repertoire of embryonic stem cells

(2013) S Chul Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Novel High Throughput Biochemical Assay to Evaluate the HuR Protein-RNA Complex Formation

(2013) Vito G. D’Agostino et al.   PLoS One

Increased Expression of Lin28B Associates with Poor Prognosis in Patients with Oral Squamous Cell Carcinoma

(2013) Tianfu Wu et al.   PLoS One

Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

(2012) Marco Radi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Functional invadopodia formation through stabilization of the PDPN transcript by IMP-3 and cancer-stromal crosstalk for PDPN expression

(2012) Young Sun Hwang et al.   CARCINOGENESIS

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

(2012) Jessica L. Bell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

(2012) Ricardo Soto-Rifo et al.   EMBO JOURNAL

Expression of insulin-like growth factor II mRNA-binding protein 3 in squamous cell carcinomas of the head and neck

(2012) T. S. Clauditz et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

(2012) Alexander G. Baltz et al.   MOLECULAR CELL

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

(2012) Ryszard Kole et al.   NATURE REVIEWS DRUG DISCOVERY

International incidence of oropharyngeal cancer: A population-based study

(2012) Marianna de Camargo Cancela et al.   ORAL ONCOLOGY

A Novel Inhibitor of Human La Protein with Anti-HBV Activity Discovered by Structure-Based Virtual Screening and In Vitro Evaluation

(2012) Jing Tang et al.   PLoS One

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

(2012) Toshifumi Yae et al.   Nature Communications

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer

(2011) Olga V. Leontieva et al.   CELL CYCLE

Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation

(2011) Giovanni Maga et al.   ChemMedChem

TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition

(2011) Takuya Shirakihara et al.   EMBO JOURNAL

HuR function in disease

(2011) Subramanya Srikantan   Frontiers in Bioscience-Landmark

Significance of molecular markers in survival prediction of oral squamous cell carcinoma

(2011) Ki-Yeol Kim et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Role of insulin-like growth factor-II mRNA-binding protein-3 in invadopodia formation and the growth of oral squamous cell carcinoma in athymic nude mice

(2011) Young Sun Hwang et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Risk stratification of oral cancer patients using a combined prognostic factor including lymph node density and biomarker

(2011) Ki-Yeol Kim et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor formation and invasion and predicts poor prognosis in oral squamous cell carcinoma

(2011) Chiao-Ying Lin et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

(2011) Svetlana Lebedeva et al.   MOLECULAR CELL

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP

(2011) K Horiguchi et al.   ONCOGENE

A novel algorithm for lymph node status prediction of oral cancer before surgery

(2011) Ki-Yeol Kim et al.   ORAL ONCOLOGY

Tumour infiltration depth ⩾4mm is an indication for an elective neck dissection in pT1cN0 oral squamous cell carcinoma

(2011) L.J. Melchers et al.   ORAL ONCOLOGY

Implication of RNA-Binding Protein La in Proliferation, Migration and Invasion of Lymph Node-Metastasized Hypopharyngeal SCC Cells

(2011) Gunhild Sommer et al.   PLoS One

Novel, Broad Spectrum Anticancer Agents Containing the Tricyclic 5:7:5-Fused Diimidazodiazepine Ring System

(2011) Atul Kondaskar et al.   ACS Medicinal Chemistry Letters

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition

(2010) Claude C Warzecha et al.   EMBO JOURNAL

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

Insulin-like growth factor II mRNA-binding protein 3: A novel prognostic biomarker for oral squamous cell carcinoma

(2010) Shengjin Li et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Association between expression of embryonic lethal abnormal vision-like protein HuR and cyclooxygenase-2 in oral squamous cell carcinoma

(2010) Jeong-Dan Cha et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

HuR Knockdown Changes the Oncogenic Potential of Oral Cancer Cells

(2010) W. Kakuguchi et al.   MOLECULAR CANCER RESEARCH

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events

(2010) Claude C. Warzecha et al.   RNA Biology

HuR is exported to the cytoplasm in oral cancer cells in a different manner from that of normal cells

(2009) H Hasegawa et al.   BRITISH JOURNAL OF CANCER

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

(2009) Yadi Wu et al.   CANCER CELL

Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-α mRNA

(2009) Min-Ju Chae et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

(2009) Claude C. Warzecha et al.   MOLECULAR CELL

Decision analysis and treatment threshold in a management for the N0 neck of the oral cavity carcinoma

(2009) Masaya Okura et al.   ORAL ONCOLOGY

Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid−Glutamic Acid−Alanine−Aspartic Acid Box Polypeptide 3

(2008) Giovanni Maga et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ring Expanded Nucleoside Analogues Inhibit RNA Helicase and Intracellular Human Immunodeficiency Virus Type 1 Replication

(2008) Venkat S. R. K. Yedavalli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

(2008) C.-S. Lee et al.   NUCLEIC ACIDS RESEARCH