The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

MicroRNAs as regulators of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   CELL CYCLE

Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression

(2011) Marcus E. Peter   CELL CYCLE

ZEB proteins link cell motility with cell cycle control and cell survival in cancer

(2011) Gareth Browne et al.   CELL CYCLE

A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells

(2010) Oliver A. Kent et al.   CANCER BIOLOGY & THERAPY

Epidermal Growth Factor Receptor and Mutant p53 Expand an Esophageal Cellular Subpopulation Capable of Epithelial-to-Mesenchymal Transition through ZEB Transcription Factors

(2010) S. Ohashi et al.   CANCER RESEARCH

microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network

(2010) Liming Zhang et al.   CARCINOGENESIS

Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions

(2010) Sivan Elloul et al.   CLINICAL & EXPERIMENTAL METASTASIS

MicroRNA-21 Is Induced Early in Pancreatic Ductal Adenocarcinoma Precursor Lesions

(2010) M. C. du Rieu et al.   CLINICAL CHEMISTRY

mir-200c Regulates Induction of Apoptosis through CD95 by Targeting FAP-1

(2010) Robert Schickel et al.   MOLECULAR CELL

miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer

(2010) S Uhlmann et al.   ONCOGENE

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

(2010) E Sánchez-Tilló et al.   ONCOGENE

miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion

(2009) Hongping Xia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells

(2009) Tisheeka R. Graham et al.   BREAST CANCER RESEARCH AND TREATMENT

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells

(2009) Y. Li et al.   CANCER RESEARCH

Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway

(2009) Z. Wang et al.   CANCER RESEARCH

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

(2009) T. Arumugam et al.   CANCER RESEARCH

Conserved MicroRNA miR-8/miR-200 and Its Target USH/FOG2 Control Growth by Regulating PI3K

(2009) Seogang Hyun et al.   CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

BMP-6 inhibits microRNA-21 expression in breast cancer through repressing δEF1 and AP-1

(2009) Jun Du et al.   CELL RESEARCH

Delta-Crystallin Enhancer Binding Factor 1 Controls the Epithelial to Mesenchymal Transition Phenotype and Resistance to the Epidermal Growth Factor Receptor Inhibitor Erlotinib in Human Head and Neck Squamous Cell Carcinoma Lines

(2009) Y. Haddad et al.   CLINICAL CANCER RESEARCH

miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

(2009) L. Adam et al.   CLINICAL CANCER RESEARCH

Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells

(2009) Q.-Q. Li et al.   CLINICAL CANCER RESEARCH

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

(2009) Jose Miguel López-Novoa et al.   EMBO Molecular Medicine

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

(2009) D. L. Gibbons et al.   GENES & DEVELOPMENT

MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer

(2009) P. Olson et al.   GENES & DEVELOPMENT

A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer

(2009) Xiaoxia Hu et al.   GYNECOLOGIC ONCOLOGY

Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: Evidence supporting a mesothelial-to-epithelial transition

(2009) Ausra Bendoraite et al.   GYNECOLOGIC ONCOLOGY

The miR200 Family of MicroRNAs Regulates WAVE3-dependent Cancer Cell Invasion

(2009) Khalid Sossey-Alaoui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases

(2009) Derek M. Dykxhoorn et al.   PLoS One

SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer

(2009) A. E. Sayan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs Differentially Regulated by Akt Isoforms Control EMT and Stem Cell Renewal in Cancer Cells

(2009) D. Iliopoulos et al.   Science Signaling

Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers

(2009) Dawn R. Cochrane et al.   Journal of Oncology

Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

(2008) Stéphane Ansieau et al.   CANCER CELL

The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer

(2008) S. Spaderna et al.   CANCER RESEARCH

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

Insulin-like Growth Factor-I-Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2008) T. R. Graham et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

The role of the ZEB family of transcription factors in development and disease

(2008) C. Vandewalle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA Expression Profiles in Serous Ovarian Carcinoma

(2008) E. J. Nam et al.   CLINICAL CANCER RESEARCH

Zeb1 links epithelial-mesenchymal transition and cellular senescence

(2008) Y. Liu et al.   DEVELOPMENT

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer

(2008) Yoshihiro Adachi et al.   FEBS LETTERS

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

(2008) Yannick Ladeiro et al.   HEPATOLOGY

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor Response to Combination Celecoxib and Erlotinib Therapy in Non-small Cell Lung Cancer Is Associated with a Low Baseline Matrix Metalloproteinase-9 and a Decline in Serum-Soluble E-Cadherin

(2008) Karen L. Reckamp et al.   Journal of Thoracic Oncology

ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease

(2008) Meenakshi Singh et al.   MODERN PATHOLOGY

Expression of the ZEB1 (δEF1) transcription factor in human: additional insights

(2008) Elaine M. Hurt et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One

The microRNA miR-8 is a conserved negative regulator of Wnt signaling

(2008) J. A. Kennell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA Discovery and Profiling in Human Embryonic Stem Cells by Deep Sequencing of Small RNA Libraries

(2008) Merav Bar et al.   STEM CELLS