The hallmarks of cancer

Large Intervening Non-Coding RNA HOTAIR is Associated with Hepatocellular Carcinoma Progression

(2013) YJ Geng et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

The p53 mRNA-Mdm2 Interaction Controls Mdm2 Nuclear Trafficking and Is Required for p53 Activation following DNA Damage

(2012) Madhavsai Gajjar et al.   CANCER CELL

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

(2012) T. Niinuma et al.   CANCER RESEARCH

Long non-coding RNAs and cancer: a new frontier of translational research?

(2012) R Spizzo et al.   ONCOGENE

Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation

(2011) Zhe Yang et al.   ANNALS OF SURGICAL ONCOLOGY

The Melanoma-Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion

(2011) D. Khaitan et al.   CANCER RESEARCH

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Progensa™ PCA3 test for prostate cancer

(2011) Xavier Durand et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

p53 regulation by ubiquitin

(2011) Christopher L. Brooks et al.   FEBS LETTERS

Control of RNA processing by a large non-coding RNA over-expressed in carcinomas

(2011) Rui Lin et al.   FEBS LETTERS

Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases

(2011) T. Gutschner et al.   GENOME RESEARCH

Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

(2011) Doron Amit et al.   Journal of Translational Medicine

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

(2011) Ci Chu et al.   MOLECULAR CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA

(2011) Rachel Litman Flynn et al.   NATURE

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

Aerosolized BC-819 Inhibits Primary but Not Secondary Lung Cancer Growth

(2011) Günther Hasenpusch et al.   PLoS One

Human Cancer Long Non-Coding RNA Transcriptomes

(2011) Ewan A. Gibb et al.   PLoS One

The genomic binding sites of a noncoding RNA

(2011) M. D. Simon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NcRNA-microchip analysis

(2011) Roland Hutzinger et al.   RNA Biology

Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion

(2010) F. Guo et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MacroRNA underdogs in a microRNA world: Evolutionary, regulatory, and biomedical significance of mammalian long non-protein-coding RNA

(2010) Leonard Lipovich et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective

(2010) J. E. Talmadge et al.   CANCER RESEARCH

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

(2010) Suyoun Chung et al.   CANCER SCIENCE

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes

(2010) Keiko Tano et al.   FEBS LETTERS

Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes

(2010) K.-M. Schmitz et al.   GENES & DEVELOPMENT

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq

(2010) Jing Zhao et al.   MOLECULAR CELL

Inhibition of Human T-Cell Proliferation by Mammalian Target of Rapamycin (mTOR) Antagonists Requires Noncoding RNA Growth-Arrest-Specific Transcript 5 (GAS5)

(2010) M. Mourtada-Maarabouni et al.   MOLECULAR PHARMACOLOGY

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS

7SK small nuclear RNA directly affects HMGA1 function in transcription regulation

(2010) S. Eilebrecht et al.   NUCLEIC ACIDS RESEARCH

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

(2010) Sophie Redon et al.   NUCLEIC ACIDS RESEARCH

InTERTpreting telomerase structure and function

(2010) H. D. M. Wyatt et al.   NUCLEIC ACIDS RESEARCH

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

(2010) Yongjun Chu et al.   NUCLEIC ACIDS RESEARCH

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

(2010) Jiayi Wang et al.   NUCLEIC ACIDS RESEARCH

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

(2010) Y Kotake et al.   ONCOGENE

Transcriptional regulation of telomeric non-coding RNA: Implications on telomere biology, replicative senescence and cancer

(2010) Corrado Caslini   RNA Biology

Genome-wide computational identification and manual annotation of human long noncoding RNA genes

(2010) H. Jia et al.   RNA

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

Unique Signatures of Long Noncoding RNA Expression in Response to Virus Infection and Altered Innate Immune Signaling

(2010) X. Peng et al.   mBio

Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes

(2010) Rebecca A Chodroff et al.   GENOME BIOLOGY

Epithelial-Mesenchymal Transition

(2009) Michael W. Klymkowsky et al.   AMERICAN JOURNAL OF PATHOLOGY

Vascular Endothelial Growth Factor

(2009) Napoleone Ferrara   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo

(2009) K. Li et al.   BLOOD

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

TERRA: telomeric repeat-containing RNA

(2009) Brian Luke et al.   EMBO JOURNAL

Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis

(2009) Imad J. Matouk et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Ribonucleases as potential modalities in anticancer therapy

(2009) Wojciech Ardelt et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Identification and characterisation of a novel antisense non-coding RNA from the RBM5 gene locus

(2009) Nina D. Rintala-Maki et al.   GENE

Long noncoding RNAs: functional surprises from the RNA world

(2009) J. E. Wilusz et al.   GENES & DEVELOPMENT

Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences

(2009) Aya Mizrahi et al.   Journal of Translational Medicine

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

(2009) Jeremy D Henson et al.   NATURE BIOTECHNOLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

(2009) Hellmut G. Augustin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Telomeric circles: universal players in telomere maintenance?

(2009) Lubomir Tomaska et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

(2009) Laura J. Ng et al.   NUCLEIC ACIDS RESEARCH

Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides

(2009) Charlton Cooper et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs as potential cancer therapeutics

(2009) P Trang et al.   ONCOGENE

HPV and Cervical Cancer: Updates on an Established Relationship

(2009) Deepthi Subramanya et al.   POSTGRADUATE MEDICINE

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of human noncoding RNAs in the control of tumorigenesis

(2009) L. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

(2009) P. P. Amaral et al.   RNA

The angiogenic switch in carcinogenesis

(2009) Vanessa Baeriswyl et al.   SEMINARS IN CANCER BIOLOGY

Involvement of Members of the Cadherin Superfamily in Cancer

(2009) G. Berx et al.   Cold Spring Harbor Perspectives in Biology

Necroptosis: A Specialized Pathway of Programmed Necrosis

(2008) Lorenzo Galluzzi et al.   CELL

3′ End Processing of a Long Nuclear-Retained Noncoding RNA Yields a tRNA-like Cytoplasmic RNA

(2008) Jeremy E. Wilusz et al.   CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Thrombospondins: from structure to therapeutics

(2008) S. Kazerounian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies

(2008) Amanda K Beck et al.   Future Oncology

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition

(2008) M. Beltran et al.   GENES & DEVELOPMENT

Phase I/II Marker Lesion Study of Intravesical BC-819 DNA Plasmid in H19 Over Expressing Superficial Bladder Cancer Refractory to Bacillus Calmette-Guerin

(2008) Abraham Ami Sidi et al.   JOURNAL OF UROLOGY

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

(2008) Xiangting Wang et al.   NATURE

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

(2008) M Mourtada-Maarabouni et al.   ONCOGENE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE

Differentiating Protein-Coding and Noncoding RNA: Challenges and Ambiguities

(2008) Marcel E. Dinger et al.   PLoS Computational Biology

Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells

(2008) Kevin V. Morris et al.   PLoS Genetics

Telomerase and its potential for therapeutic intervention

(2007) P Phatak et al.   BRITISH JOURNAL OF PHARMACOLOGY