LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity

Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis

(2020) Tengxiang Chen et al.   ONCOLOGY REPORTS

Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer

(2020) Yung‐Ding Bow et al.   ORAL DISEASES

Pancreatic cancer-derived organoids – a disease modeling tool to predict drug response

(2020) Pierre-Olivier Frappart et al.   United European Gastroenterology Journal

Clinical spectrum and pleiotropic nature of CDH1 germline mutations

(2019) Joana Figueiredo et al.   JOURNAL OF MEDICAL GENETICS

Prognostic Role of High-Grade Tumor Budding in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis with a Focus on Epithelial to Mesenchymal Transition

(2019) Rita Lawlor et al.   Cancers

Molecular subtypes of pancreatic cancer

(2019) Eric A. Collisson et al.   Nature Reviews Gastroenterology & Hepatology

The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration

(2019) Daniel T. Swarr et al.   GENES & DEVELOPMENT

LINC00261 is an epigenetically-regulated tumor suppressor that is essential for activation of the DNA damage response

(2019) Shandy Shahabi et al.   CANCER RESEARCH

Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis

(2019) Wei Lu et al.   DEVELOPMENTAL CELL

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation

(2019) Kihyun Lee et al.   Cell Reports

Identification of lncRNAs associated with lung squamous cell carcinoma prognosis in the competitive endogenous RNA network

(2019) Lingyu Qi et al.   PeerJ

Identifying prognostic biomarkers in endometrial carcinoma based on ceRNA network

(2019) Dongli Zhao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Up-regulated LINC00261 predicts a poor prognosis and promotes a metastasis by EMT process in cholangiocarcinoma

(2019) Jianjun Gao et al.   PATHOLOGY RESEARCH AND PRACTICE

Long Noncoding RNA LL35/Falcor Regulates Expression of Transcription Factor Foxa2 in Hepatocytes in Normal and Fibrotic Mouse Liver

(2019) O.V. Sergeeva et al.   Acta Naturae

Construction of a Competitive Endogenous RNA Network in Uterine Corpus Endometrial Carcinoma

(2019) Dong Ouyang et al.   MEDICAL SCIENCE MONITOR

A Long Non-coding RNA Signature to Improve Prognostic Prediction of Pancreatic Ductal Adenocarcinoma

(2019) Chenhao Zhou et al.   Frontiers in Oncology

LINC00261 suppresses cell proliferation, invasion and Notch signaling pathway in hepatocellular carcinoma

(2018) Hai-Feng Zhang et al.   Cancer Biomarkers

LncRNA co-expression network analysis reveals novel biomarkers for pancreatic cancer

(2018) Matteo Giulietti et al.   CARCINOGENESIS

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

(2018) Takashi Seino et al.   Cell Stem Cell

EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration

(2018) Nicole M. Aiello et al.   DEVELOPMENTAL CELL

Genome-Wide Analysis Identified a Number of Dysregulated Long Noncoding RNA (lncRNA) in Human Pancreatic Ductal Adenocarcinoma

(2018) Sijie Hao et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

FOXA2 promotes the proliferation, migration and invasion, and epithelial mesenchymal transition in colon cancer

(2018) Baolei Wang et al.   Experimental and Therapeutic Medicine

Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes

(2018) Gwen Lomberk et al.   Nature Communications

Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma

(2018) Dingyuan Hu et al.   Oncotarget

Long noncoding RNA LINC00261 induces chemosensitization to 5-fluorouracil by mediating methylation-dependent repression of DPYD in human esophageal cancer

(2018) Kai Lin et al.   FASEB JOURNAL

Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features

(2018) Francesco Puleo et al.   GASTROENTEROLOGY

Non-redundant functions of EMT transcription factors

(2018) Marc P. Stemmler et al.   NATURE CELL BIOLOGY

Upholding a role for EMT in breast cancer metastasis

(2017) Xin Ye et al.   NATURE

Upholding a role for EMT in pancreatic cancer metastasis

(2017) Nicole M. Aiello et al.   NATURE

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

(2017) Angela M. Krebs et al.   NATURE CELL BIOLOGY

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Analysis of distinct long noncoding RNA transcriptional fingerprints in pancreatic ductal adenocarcinoma

(2017) Xiang Yu et al.   Cancer Medicine

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Long non-coding RNA linc00261 suppresses gastric cancer progressionviapromoting Slug degradation

(2016) Yingcong Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

(2016) Jill E. Larsen et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

Promoter methylation and expression of CDH1 and susceptibility and prognosis of eyelid squamous cell carcinoma

(2016) Yong-Qiang Wang et al.   TUMOR BIOLOGY

Construction and analysis of dysregulated lncRNA-associated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic cancer

(2016) Meng Zhou et al.   Oncotarget

Transcriptome profiling reveals novel gene expression signatures and regulating transcription factors of TGFβ-induced epithelial-to-mesenchymal transition

(2016) Liutao Du et al.   Cancer Medicine

Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinoma

(2016) Xue-Liang Fu et al.   Scientific Reports

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

(2015) Richard A Moffitt et al.   NATURE GENETICS

The lncRNA DEANR1 Facilitates Human Endoderm Differentiation by Activating FOXA2 Expression

(2015) Wei Jiang et al.   Cell Reports

Rare Drosha Splice Variants Are Deficient in MicroRNA Processing but Do Not Affect General MicroRNA Expression in Cancer Cells

(2015) Stefanie E. Grund et al.   NEOPLASIA

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

FOXA2 suppresses the metastasis of hepatocellular carcinoma partially through matrix metalloproteinase-9 inhibition

(2014) Jian Wang et al.   CARCINOGENESIS

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma

(2014) Tony Gutschner et al.   HEPATOLOGY

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell-Mediated Lysis

(2013) I. Akalay et al.   CANCER RESEARCH

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

FOXOs attenuate bone formation by suppressing Wnt signaling

(2013) Srividhya Iyer et al.   JOURNAL OF CLINICAL INVESTIGATION

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer

(2013) Suguru Yamada et al.   SURGERY

Analysis of long non-coding RNA expression profiles in gastric cancer

(2013) Wei-Jun Cao   WORLD JOURNAL OF GASTROENTEROLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

Tumour budding is a strong and independent prognostic factor in pancreatic cancer

(2012) E. Karamitopoulou et al.   EUROPEAN JOURNAL OF CANCER

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

β-Catenin signaling regulates Foxa2 expression during endometrial hyperplasia formation

(2012) M Villacorte et al.   ONCOGENE

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

A flexible R package for nonnegative matrix factorization

(2010) Renaud Gaujoux et al.   BMC BIOINFORMATICS

Loss of FOXA1/2 Is Essential for the Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

(2010) Y. Song et al.   CANCER RESEARCH

FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers

(2010) Yunneng Tang et al.   CELL RESEARCH

Phenotype and Genotype of Pancreatic Cancer Cell Lines

(2010) Emily L. Deer et al.   PANCREAS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

(2009) T. Arumugam et al.   CANCER RESEARCH

Mechanisms of the epithelial–mesenchymal transition by TGF-β

(2009) Michael K Wendt et al.   Future Oncology

E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex

(2009) Johannes von Burstin et al.   GASTROENTEROLOGY

LY2109761, a novel transforming growth factor   receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

(2008) D. Melisi et al.   MOLECULAR CANCER THERAPEUTICS