Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection
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Title
Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-12-06
DOI
10.3389/fgene.2014.00423
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Note: Only part of the references are listed.- DDX3 DEAD-Box RNA Helicase Is a Host Factor That Restricts Hepatitis B Virus Replication at the Transcriptional Level
- (2014) C. Ko et al. JOURNAL OF VIROLOGY
- Host Factors That Interact with the Pestivirus N-Terminal Protease, Npro, Are Components of the Ribonucleoprotein Complex
- (2014) M. Jefferson et al. JOURNAL OF VIROLOGY
- DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway
- (2014) H-H Chen et al. ONCOGENE
- Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases
- (2014) Megha Haridas Upadya WORLD JOURNAL OF GASTROENTEROLOGY
- Cytoplasmic RNA Granules and Viral Infection
- (2014) Wei-Chih Tsai et al. Annual Review of Virology
- DDX3 RNA helicase is required for HIV-1 Tat function
- (2013) Mariko Yasuda-Inoue et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function
- (2013) Mariko Yasuda-Inoue et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- DDX3 regulates DNA damage-induced apoptosis and p53 stabilization
- (2013) Mianen Sun et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Human DEAD Box Helicase 3 Couples I B Kinase to Interferon Regulatory Factor 3 Activation
- (2013) L. Gu et al. MOLECULAR AND CELLULAR BIOLOGY
- The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA
- (2013) Ricardo Soto-Rifo et al. NUCLEIC ACIDS RESEARCH
- DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer
- (2013) D-W Wu et al. ONCOGENE
- Low/negative expression of DDX3 might predict poor prognosis in non-smoker patients with oral cancer
- (2013) C-H Lee et al. ORAL DISEASES
- Determination of the Role of DDX3 a Factor Involved in Mammalian RNAi Pathway Using an shRNA-Expression Library
- (2013) Vivi Kasim et al. PLoS One
- DDX5 Facilitates HIV-1 Replication as a Cellular Co-Factor of Rev
- (2013) Xiuxia Zhou et al. PLoS One
- Human DDX3 Interacts with the HIV-1 Tat Protein to Facilitate Viral mRNA Translation
- (2013) Ming-Chih Lai et al. PLoS One
- RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling
- (2013) C.-M. Cruciat et al. SCIENCE
- Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions
- (2013) Chen Li et al. VIROLOGY
- PML tumor suppressor protein is required for HCV production
- (2012) Misao Kuroki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors
- (2012) Marco Radi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs
- (2012) Ricardo Soto-Rifo et al. EMBO JOURNAL
- Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life Cycle
- (2012) S. Vashist et al. JOURNAL OF VIROLOGY
- The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes
- (2012) Rene Geissler et al. NUCLEIC ACIDS RESEARCH
- From promoting to inhibiting: diverse roles of helicases in HIV-1 Replication
- (2012) Rene-Pierre Lorgeoux et al. Retrovirology
- P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication
- (2012) Harendra S. Chahar et al. VIROLOGY
- Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response
- (2011) Jing-Wen Shih et al. BIOCHEMICAL JOURNAL
- Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation
- (2011) Giovanni Maga et al. ChemMedChem
- Reduced p21WAF1/CIP1 via Alteration of p53-DDX3 Pathway Is Associated with Poor Relapse-Free Survival in Early-Stage Human Papillomavirus-Associated Lung Cancer
- (2011) D.-W. Wu et al. CLINICAL CANCER RESEARCH
- The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2/M phase of the cycle, and affects its shuttling during mRNP export
- (2011) Yeo-Jin Choi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Single-Molecule Studies Reveal that DEAD Box Protein DDX1 Promotes Oligomerization of HIV-1 Rev on the Rev Response Element
- (2011) Rae M. Robertson-Anderson et al. JOURNAL OF MOLECULAR BIOLOGY
- Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production
- (2011) Souad Naji et al. MOLECULAR & CELLULAR PROTEOMICS
- The DEAD-Box Protein Ded1 Modulates Translation by the Formation and Resolution of an eIF4F-mRNA Complex
- (2011) Angela Hilliker et al. MOLECULAR CELL
- Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells
- (2011) Mahendran Botlagunta et al. PLoS One
- The ESCRT System Is Required for Hepatitis C Virus Production
- (2011) Yasuo Ariumi et al. PLoS One
- The molecular evolution of PL10 homologs
- (2010) Ti-Cheng Chang et al. BMC EVOLUTIONARY BIOLOGY
- DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential
- (2010) Hiroyuki Oshiumi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKK and DDX3
- (2010) S. Yu et al. JOURNAL OF GENERAL VIROLOGY
- DDX6 (Rck/p54) Is Required for Efficient Hepatitis C Virus Replication but Not for Internal Ribosome Entry Site-Directed Translation
- (2010) R. K. Jangra et al. JOURNAL OF VIROLOGY
- DDX3 Regulates Cell Growth through Translational Control of Cyclin E1
- (2010) M.-C. Lai et al. MOLECULAR AND CELLULAR BIOLOGY
- Hepatitis C Virus Core-Derived Peptides Inhibit Genotype 1b Viral Genome Replication via Interaction with DDX3X
- (2010) Chaomin Sun et al. PLoS One
- Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction
- (2010) Hiroyuki Oshiumi et al. PLoS One
- RNA helicases at work: binding and rearranging
- (2010) Eckhard Jankowsky TRENDS IN BIOCHEMICAL SCIENCES
- Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion
- (2010) Haifeng Wang et al. PLoS Pathogens
- Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation
- (2009) Martina Schröder BIOCHEMICAL PHARMACOLOGY
- Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein
- (2009) A. G. N. Angus et al. JOURNAL OF GENERAL VIROLOGY
- DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids
- (2009) H. Wang et al. JOURNAL OF VIROLOGY
- Human Cytomegalovirus Induces the Interferon Response via the DNA Sensor ZBP1
- (2009) V. R. DeFilippis et al. JOURNAL OF VIROLOGY
- Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates
- (2009) N. Scheller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis for Targeting of Human RNA Helicase DDX3 by Poxvirus Protein K7
- (2009) Shun-ichiro Oda et al. STRUCTURE
- Tumor Suppressors, Chromosomal Instability, and Hepatitis C Virus–Associated Liver Cancer
- (2008) David R. McGivern et al. Annual Review of Pathology-Mechanisms of Disease
- Identification of an antiapoptotic protein complex at death receptors
- (2008) M Sun et al. CELL DEATH AND DIFFERENTIATION
- P Bodies, Stress Granules, and Viral Life Cycles
- (2008) Carla J. Beckham et al. Cell Host & Microbe
- mRNA Export: RNP Remodeling by DEAD-Box Proteins
- (2008) Patrick Linder CURRENT BIOLOGY
- The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response
- (2008) Didier Soulat et al. EMBO JOURNAL
- Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation
- (2008) Martina Schröder et al. EMBO JOURNAL
- Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid−Glutamic Acid−Alanine−Aspartic Acid Box Polypeptide 3
- (2008) Giovanni Maga et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ring Expanded Nucleoside Analogues Inhibit RNA Helicase and Intracellular Human Immunodeficiency Virus Type 1 Replication
- (2008) Venkat S. R. K. Yedavalli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3
- (2008) Arnout P. Kalverda et al. JOURNAL OF MOLECULAR BIOLOGY
- The DEAD-Box RNA Helicase DDX3 Associates with Export Messenger Ribonucleoproteins as well asTip-associated Protein and Participates in Translational Control
- (2008) Ming-Chih Lai et al. MOLECULAR BIOLOGY OF THE CELL
- Knockdown of Cellular RNA Helicase DDX3 by Short Hairpin RNAs Suppresses HIV-1 Viral Replication Without Inducing Apoptosis
- (2008) Musarat Ishaq et al. MOLECULAR BIOTECHNOLOGY
- Human DDX3 functions in translation and interacts with the translation initiation factor eIF3
- (2008) C.-S. Lee et al. NUCLEIC ACIDS RESEARCH
- Oncogenic role of DDX3 in breast cancer biogenesis
- (2008) M Botlagunta et al. ONCOGENE
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