COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status

COVID-19: the gendered impacts of the outbreak

(2020) Clare Wenham et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

(2020) Xiaobo Yang et al.   Lancet Respiratory Medicine

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes

(2020) Lihua Zhu et al.   Cell Metabolism

Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients

(2020) Hong-Yi Zheng et al.   Cellular & Molecular Immunology

Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

(2020) Tingting Xie et al.   CIRCULATION RESEARCH

COVID-19 and diabetes: Knowledge in progress

(2020) Akhtar Hussain et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

(2020) Philippe Gautret et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

SARS-CoV-2: a storm is raging

(2020) Savannah F. Pedersen et al.   JOURNAL OF CLINICAL INVESTIGATION

Deployment of convalescent plasma for the prevention and treatment of COVID-19

(2020) Evan M. Bloch et al.   JOURNAL OF CLINICAL INVESTIGATION

Reply: Potential role of Janus kinase inhibitors in COVID-19

(2020) Maddalena Napolitano et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Recommendations for phototherapy during the COVID-19 pandemic

(2020) Henry W. Lim et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Tissue plasminogen activator (tPA) treatment for COVID‐19 associated acute respiratory distress syndrome (ARDS): A case series

(2020) Janice Wang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

The race for coronavirus vaccines: a graphical guide

(2020) Ewen Callaway   NATURE

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

‘These are answers we need.’ WHO plans global study to discover true extent of coronavirus infections

(2020) Gretchen Vogel   SCIENCE

Against pandemic research exceptionalism

(2020) Alex John London et al.   SCIENCE

Impact of taurine on red blood cell metabolism and implications for blood storage

(2020) Lorenzo Bertolone et al.   TRANSFUSION

Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig

(2020) Changhai Lei et al.   Nature Communications

Pulmonary thromboembolism in critical ill COVID-19 patients

(2020) Michele Scialpi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

(2020) Bingwen Liu et al.   JOURNAL OF AUTOIMMUNITY

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication

(2019) Bingpeng Yan et al.   Viruses-Basel

Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice

(2019) Benjamin M. Fox et al.   KIDNEY INTERNATIONAL

TNF-alpha driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

(2019) Pavel Davizon-Castillo et al.   BLOOD

Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells

(2019) Evan J. Morrison et al.   Nutrients

Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice

(2019) Dov B. Ballak et al.   AGING CELL

Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage

(2019) Davide Stefanoni et al.   HAEMATOLOGICA

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

(2019) Rani K. Powers et al.   Nature Communications

The plasma metabolome as a predictor of biological aging in humans

(2019) Lawrence C. Johnson et al.   GeroScience

Regulation of plasminogen activation on cell surfaces and fibrin

(2018) T. Urano et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation

(2018) Carlo Marchetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for Tryptophan-2,3-dioxygenase in CD8 T Cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma

(2018) Lisa I Greene et al.   MOLECULAR CANCER RESEARCH

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

(2017) Giada Mondanelli et al.   IMMUNITY

The expansive role of oxylipins on platelet biology

(2017) Jennifer Yeung et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Plasma succinate is a predictor of mortality in critically injured patients

(2017) Angelo DʼAlessandro et al.   Journal of Trauma and Acute Care Surgery

Inhibition of acute lethal pulmonary inflammation by the IDO–AhR pathway

(2017) Soung-Min Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

(2017) Giulio Cavalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis

(2017) Ingrid Pabinger et al.   WIENER KLINISCHE WOCHENSCHRIFT

Plasma succinate is a predictor of mortality in critically injured patients

(2017) Angelo DʼAlessandro et al.   Journal of Trauma and Acute Care Surgery

The interplay between cytokines and the Kynurenine pathway in inflammation and atherosclerosis

(2017) Roland Baumgartner et al.   CYTOKINE

Individual variability in human blood metabolites identifies age-related differences

(2016) Romanas Chaleckis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia

(2016) Kaiqi Sun et al.   Nature Communications

Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation

(2016) Wejdan A. Aldajani et al.   Oncotarget

Early hemorrhage triggers metabolic responses that build up during prolonged shock

(2015) Angelo D'Alessandro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data

(2015) H. Deguchi et al.   BLOOD

A TDO2-AhR Signaling Axis Facilitates Anoikis Resistance and Metastasis in Triple-Negative Breast Cancer

(2015) Nicholas C. D'Amato et al.   CANCER RESEARCH

Trauma/hemorrhagic shock instigates aberrant metabolic flux through glycolytic pathways, as revealed by preliminary 13C-glucose labeling metabolomics

(2015) Angelo D’Alessandro et al.   Journal of Translational Medicine

Pathologic metabolism

(2015) Erik D. Peltz et al.   Journal of Trauma and Acute Care Surgery

Pathologic metabolism

(2015) Erik D. Peltz et al.   Journal of Trauma and Acute Care Surgery

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

De novo Fatty Acid Biosynthesis Contributes Significantly to Establishment of a Bioenergetically Favorable Environment for Vaccinia Virus Infection

(2014) Matthew D. Greseth et al.   PLoS Pathogens

Mechanisms of Severe Acute Respiratory Syndrome Pathogenesis and Innate Immunomodulation

(2008) M. Frieman et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS