De novo Fatty Acid Biosynthesis Contributes Significantly to Establishment of a Bioenergetically Favorable Environment for Vaccinia Virus Infection

Stalling the Engine of Resistance: Targeting Cancer Metabolism to Overcome Therapeutic Resistance

(2013) E. B. Butler et al.   CANCER RESEARCH

Modulation of Fatty Acid Synthase Enzyme Activity and Expression during Hepatitis C Virus Replication

(2013) Neda Nasheri et al.   CHEMISTRY & BIOLOGY

Hepatitis C Virus Replication Is Modulated by the Interaction of Nonstructural Protein NS5B and Fatty Acid Synthase

(2013) J.-T. Huang et al.   JOURNAL OF VIROLOGY

A mechanism for induction of a hypoxic response by vaccinia virus

(2013) M. Mazzon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Novel triacsin C analogs as potential antivirals against rotavirus infections

(2012) Yunjeong Kim et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Modulation of Fatty Acid Synthase Degradation by Concerted Action of p38 MAP Kinase, E3 Ligase COP1, and SH2-Tyrosine Phosphatase Shp2

(2012) Jianxiu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Genetic and Biochemical Characterization of the Vaccinia Virus I3 Protein, the Replicative Single-Stranded DNA Binding Protein

(2012) M. D. Greseth et al.   JOURNAL OF VIROLOGY

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

(2012) Marlen Knobloch et al.   NATURE

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

(2011) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human Cytomegalovirus Induces the Activity and Expression of Acetyl-Coenzyme A Carboxylase, a Fatty Acid Biosynthetic Enzyme Whose Inhibition Attenuates Viral Replication

(2011) C. M. Spencer et al.   JOURNAL OF VIROLOGY

FKBP12 Binds to Acylated H-Ras and Promotes Depalmitoylation

(2011) Ian M. Ahearn et al.   MOLECULAR CELL

Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection

(2011) Yongjun Yu et al.   TRENDS IN MICROBIOLOGY

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

(2010) Lisa S. Pike et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1

(2010) M. J. Seltzer et al.   CANCER RESEARCH

Fatty acid synthase as a potential therapeutic target in cancer

(2010) Richard Flavin et al.   Future Oncology

Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication

(2010) W. Cheung et al.   JOURNAL OF VIROLOGY

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis

(2010) N. S. Heaton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis

(2010) C.-W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: Molecular mechanisms and therapeutic perspectives

(2009) Javier A. Menendez   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway

(2009) Chul-Yong Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine Metabolism Is Essential for Human Cytomegalovirus Infection

(2009) J. W. Chambers et al.   JOURNAL OF VIROLOGY

Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production

(2008) Wei Yang et al.   HEPATOLOGY

Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2

(2008) J.-K. Oem et al.   JOURNAL OF GENERAL VIROLOGY

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

(2008) Joshua Munger et al.   NATURE BIOTECHNOLOGY