Trauma/hemorrhagic shock instigates aberrant metabolic flux through glycolytic pathways, as revealed by preliminary 13C-glucose labeling metabolomics

Early hemorrhage triggers metabolic responses that build up during prolonged shock

(2015) Angelo D'Alessandro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A roadmap for interpreting 13 C metabolite labeling patterns from cells

(2015) Joerg M Buescher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Pathologic metabolism

(2015) Erik D. Peltz et al.   Journal of Trauma and Acute Care Surgery

Combat

(2015) Michael P. Chapman et al.   SHOCK

Pathologic metabolism

(2015) Erik D. Peltz et al.   Journal of Trauma and Acute Care Surgery

Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites

(2014) Romanas Chaleckis et al.   Molecular BioSystems

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Dynamic Changes in Rat Mesenteric Lymph Proteins Following Trauma Using Label-Free Mass Spectrometry

(2014) Angelo D’Alessandro et al.   SHOCK

Lymph Is Not a Plasma Ultrafiltrate

(2014) Monika Dzieciatkowska et al.   SHOCK

Routine storage of red blood cell (RBC) units in additive solution-3: a comprehensive investigation of the RBC metabolome

(2014) Angelo D'Alessandro et al.   TRANSFUSION

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Plasma First in the Field for Postinjury Hemorrhagic Shock

(2013) Ernest E. Moore et al.   SHOCK

Metabolomics classifies phase of care and identifies risk for mortality in a porcine model of multiple injuries and hemorrhagic shock

(2012) Daniel R. Lexcen et al.   Journal of Trauma and Acute Care Surgery

The Emerging Field of Quantitative Blood Metabolomics for Biomarker Discovery in Critical Illnesses

(2011) Natalie J. Serkova et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Global Metabolic Phenotyping in an Experimental Laparotomy Model of Surgical Trauma

(2010) James M. Kinross et al.   JOURNAL OF PROTEOME RESEARCH

A Review of metabolic staging in severely injured patients

(2010) Maria-Angeles Aller et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

"Metabolic staging" after major trauma - a guide for clinical decision making?

(2010) Philip F Stahel et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

1H-NMR-Based Metabolic Signatures of Clinical Outcomes in Trauma Patients—Beyond Lactate and Base Deficit

(2010) Mitchell J. Cohen et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Polyamine Catabolism Is Enhanced after Traumatic Brain Injury

(2009) Kamyar Zahedi et al.   JOURNAL OF NEUROTRAUMA

Systemic Metabolic Changes of Traumatic Critically Ill Patients Revealed by an NMR-Based Metabonomic Approach

(2009) Hailei Mao et al.   JOURNAL OF PROTEOME RESEARCH

Postinjury Life Threatening Coagulopathy: Is 1:1 Fresh Frozen Plasma: Packed Red Blood Cells the Answer?

(2009) Jeffry L. Kashuk et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE