Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy

Tumour-derived extracellular vesicles in blood of metastatic cancer patients associate with overall survival

(2020) Afroditi Nanou et al.   BRITISH JOURNAL OF CANCER

Metal–Organic Framework Nanoparticles for Ameliorating Breast Cancer-Associated Osteolysis

(2020) Yichuan Pang et al.   NANO LETTERS

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

(2020) John D. Martin et al.   Nature Reviews Clinical Oncology

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

(2020) Marc Rigau et al.   SCIENCE

Applications and strategies in nanodiagnosis and nanotherapy in lung cancer

(2020) Christopher Woodman et al.   SEMINARS IN CANCER BIOLOGY

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

(2020) Phuong-Uyen C. Dinh et al.   Nature Communications

Nanoformulated Zoledronic Acid Boosts the Vδ2 T Cell Immunotherapeutic Potential in Colorectal Cancer

(2020) Daniele Di Mascolo et al.   Cancers

Altered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake

(2020) Nao Nishida-Aoki et al.   Journal of Extracellular Vesicles

The function and clinical application of extracellular vesicles in innate immune regulation

(2020) Xiaoxue Zhou et al.   Cellular & Molecular Immunology

Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing

(2020) Mohindar M. Karunakaran et al.   IMMUNITY

Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma

(2020) Hinrich P. Hansen et al.   Frontiers in Immunology

NKG2D Ligand Shedding in Response to Stress: Role of ADAM10

(2020) Alessandra Zingoni et al.   Frontiers in Immunology

Natural-Killer-Derived Extracellular Vesicles: Immune Sensors and Interactors

(2020) Cristina Federici et al.   Frontiers in Immunology

Immunogenicity of cell death driven by immune effectors

(2020) Lorenzo Galluzzi et al.   Journal for ImmunoTherapy of Cancer

Nanoparticles to Improve the Efficacy of Peptide-Based Cancer Vaccines

(2020) Anna Lucia Tornesello et al.   Cancers

Phage display-identified PD-L1-binding peptides reinvigorate T-cell activity and inhibit tumor progression

(2020) Smriti Gurung et al.   BIOMATERIALS

Zoledronate

(2020) Ian R. Reid et al.   BONE

Tumor microenvironment-induced structure changing drug/gene delivery system for overcoming delivery-associated challenges

(2020) Min Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Drug-loaded exosomal preparations from different cell types exhibit distinctive loading capability, yield, and antitumor efficacies: a comparative analysis

(2019) Rajashekhar Kanchanapally et al.   International Journal of Nanomedicine

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

ADAM10 mediates malignant pleural mesothelioma invasiveness

(2019) Christelle Sépult et al.   ONCOGENE

Exosome origin determines cell targeting and the transfer of therapeutic nanoparticles towards target cells

(2019) María Sancho-Albero et al.   JOURNAL OF NANOBIOTECHNOLOGY

Cancer Exosomes as Conveyors of Stress-Induced Molecules: New Players in the Modulation of NK Cell Response

(2019) Elisabetta Vulpis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer

(2019) Wenting Liao et al.   CANCER CELL

Extracellular acidity and increased exosome release as key phenotypes of malignant tumors

(2019) Mariantonia Logozzi et al.   CANCER AND METASTASIS REVIEWS

Zoledronic Acid-containing Nanoparticles With Minimum Premature Release Show Enhanced Activity Against Extraskeletal Tumor

(2019) Xu Li et al.   ACS Applied Materials & Interfaces

Generation of the heterogeneity of extracellular vesicles by membrane organization and sorting machineries

(2019) Yoichiro Harada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A supporting ecosystem to mature extracellular vesicles into clinical application

(2019) Olivier De Wever et al.   EMBO JOURNAL

Formation of the Immunosuppressive Microenvironment of Classic Hodgkin Lymphoma and Therapeutic Approaches to Counter It

(2019) Donatella Aldinucci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy

(2019) Faezeh Vakhshiteh et al.   International Journal of Nanomedicine

The Interplay between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses

(2019) Seyed Moein Moghimi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Exosome-orchestrated hypoxic tumor microenvironment

(2019) Wanrong Meng et al.   Molecular Cancer

Targeted Delivery of Zoledronate to Tumor-Associated Macrophages for Cancer Immunotherapy

(2019) Xinlong Zang et al.   MOLECULAR PHARMACEUTICS

Management of bone health in solid tumours: From bisphosphonates to a monoclonal antibody

(2019) Roger von Moos et al.   CANCER TREATMENT REVIEWS

γδ T Cell Update: Adaptate Orchestrators of Immune Surveillance

(2019) Adrian C. Hayday   JOURNAL OF IMMUNOLOGY

The biology of extracellular vesicles: The known unknowns

(2019) Leonid Margolis et al.   PLOS BIOLOGY

Hyaluronic Acid-Coated Nanomedicine for Targeted Cancer Therapy

(2019) Kim et al.   Pharmaceutics

Mesenchymal Stem Cells for Regenerative Medicine

(2019) Yu Han et al.   Cells

Small extracellular vesicle loading systems in cancer therapy: Current status and the way forward

(2019) Yue-Feng Zhang et al.   CYTOTHERAPY

Extracellular vesicles in metabolic disease

(2019) Naveed Akbar et al.   DIABETOLOGIA

Smart Targeting To Improve Cancer Therapeutics

(2019) Moraima Morales-Cruz et al.   Drug Design Development and Therapy

Simvastatin mediates inhibition of exosome synthesis, localization and secretion via multicomponent interventions

(2019) Ankur Kulshreshtha et al.   Scientific Reports

Stem cell-derived extracellular vesicles: role in oncogenic processes, bioengineering potential, and technical challenges

(2019) Mujib Ullah et al.   Stem Cell Research & Therapy

Harnessing Natural Killer Cell Antitumor Immunity: From the Bench to Bedside

(2019) Karrune V. Woan et al.   Cancer Immunology Research

Natural Killer Cell Therapy: A New Treatment Paradigm for Solid Tumors

(2019) Sooyeon Oh et al.   Cancers

Extracellular Vesicles as Natural, Safe and Efficient Drug Delivery Systems

(2019) Federico Villa et al.   Pharmaceutics

Functional extracellular vesicles engineered with lipid-grafted hyaluronic acid effectively reverse cancer drug resistance

(2019) Jia Liu et al.   BIOMATERIALS

Repurposing amino-bisphosphonates by liposome formulation for a new role in cancer treatment

(2019) Ninh M. La-Beck et al.   SEMINARS IN CANCER BIOLOGY

Advances in Hypoxia-Inducible Factor Biology

(2018) Hani Choudhry et al.   Cell Metabolism

Proteolytic ectodomain shedding of membrane proteins in mammals—hardware, concepts, and recent developments

(2018) Stefan F Lichtenthaler et al.   EMBO JOURNAL

Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment

(2018) M. Garofalo et al.   JOURNAL OF CONTROLLED RELEASE

Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria

(2018) Tomas Majtan et al.   LIFE SCIENCES

Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation

(2018) Jing-Hung Wang et al.   MOLECULAR CANCER THERAPEUTICS

Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles

(2018) Chonlada Charoenviriyakul et al.   MOLECULAR PHARMACEUTICS

Structural Characterization of Self-Assembling Hybrid Nanoparticles for Bisphosphonate Delivery in Tumors

(2018) Sandra Ristori et al.   MOLECULAR PHARMACEUTICS

A33 antibody-functionalized exosomes for targeted delivery of doxorubicin against colorectal cancer

(2018) Yan Li et al.   Nanomedicine-Nanotechnology Biology and Medicine

Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations

(2018) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin’s Lymphoma

(2018) Joseph M. Connors et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity

(2018) Lucas Ferrari de Andrade et al.   SCIENCE

Advances in targeting the folate receptor in the treatment/imaging of cancers

(2018) Marcos Fernández et al.   Chemical Science

Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility

(2018) Jayesh A. Kulkarni et al.   Nucleic Acid Therapeutics

Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19

(2018) Jing Ren et al.   Theranostics

NKG2D and Its Ligands: “One for All, All for One”

(2018) Alessandra Zingoni et al.   Frontiers in Immunology

Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells

(2018) Francesca Tosetti et al.   OncoImmunology

Synthesis and in vitro Evaluation of ADAM10 and ADAM17 Highly Selective Bioimaging Probes

(2018) Caterina Camodeca et al.   ChemMedChem

Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines

(2018) Waliul Islam et al.   MOLECULAR CANCER THERAPEUTICS

Recombinant phosphatidylserine-binding nanobodies for targeting of extracellular vesicles to tumor cells: a plug-and-play approach

(2018) Sander A. A. Kooijmans et al.   Nanoscale

Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds

(2018) Rolake O. Alabi et al.   PHYSIOLOGICAL REVIEWS

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

(2018) Hosna Gomari et al.   OncoTargets and Therapy

A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy

(2018) Senthilkumar Kalimuthu et al.   Frontiers in Pharmacology

Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p

(2018) Yao-yin Li et al.   EBioMedicine

Early disease progression and treatment discontinuation in patients with advanced ovarian cancer receiving immune checkpoint blockade

(2018) Julia L. Boland et al.   GYNECOLOGIC ONCOLOGY

Extracellular Vesicles: New Players in Lymphomas

(2018) Victor Navarro-Tableros et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protein-based nanoparticles in cancer vaccine development

(2018) Medea Neek et al.   Nanomedicine-Nanotechnology Biology and Medicine

Plant Lectins Targeting O-Glycans at the Cell Surface as Tools for Cancer Diagnosis, Prognosis and Therapy

(2017) Guillaume Poiroux et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fabrication and physicochemical characterization of porous composite microgranules with selenium oxyanions and risedronate sodium for potential applications in bone tumors

(2017) Joanna Kolmas et al.   International Journal of Nanomedicine

Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer

(2017) Evgenia Karousou et al.   MATRIX BIOLOGY

Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial–mesenchymal transition through the regulation of ADAM10 and ADAM17

(2017) Ga Bin Park et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A Novel Therapeutic Strategy for Pancreatic Cancer: Targeting Cell Surface Glycan Using rBC2LC-N Lectin–Drug Conjugate (LDC)

(2017) Osamu Shimomura et al.   MOLECULAR CANCER THERAPEUTICS

Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles

(2017) Aisling J. O’Loughlin et al.   MOLECULAR THERAPY

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

(2017) Fengmei Pi et al.   Nature Nanotechnology

Monitoring immune-checkpoint blockade: response evaluation and biomarker development

(2017) Mizuki Nishino et al.   Nature Reviews Clinical Oncology

Cancer drug delivery in the nano era: An overview and perspectives

(2017) Zhen Li et al.   ONCOLOGY REPORTS

NK cell-based immunotherapy for cancer

(2017) Fang Fang et al.   SEMINARS IN IMMUNOLOGY

Alendronate promotes osteoblast differentiation and bone formation in ovariectomy‑induced osteoporosis through interferon‑β/signal transducer and activator of transcription 1 pathway

(2017) Xiaoqing Ma et al.   Experimental and Therapeutic Medicine

Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells

(2017) Cinzia Borghese et al.   Oncotarget

Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies

(2017) Jiayin Shen et al.   Oncotarget

Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth

(2017) Daniele Bellavia et al.   Theranostics

Exploring the Role of RGD-Recognizing Integrins in Cancer

(2017) Markus Nieberler et al.   Cancers

Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy

(2017) Seema Gupta et al.   Frontiers in Oncology

Liposomal Formulations in Clinical Use: An Updated Review

(2017) Upendra Bulbake et al.   Pharmaceutics

Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes

(2017) Erez Eitan et al.   Scientific Reports

Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug

(2017) Yoshimasa Tanaka et al.   Scientific Reports

Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

(2016) Nazila Kamaly et al.   CHEMICAL REVIEWS

Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors

(2016) D. D. Von Hoff et al.   CLINICAL CANCER RESEARCH

Nanoparticle-siRNA: A potential cancer therapy?

(2016) Samuel Wang Sherng Young et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors

(2016) Jonathan M. Pitt et al.   IMMUNITY

Transferrin-Targeted Nanoparticles Containing Zoledronic Acid as a Potential Tool to Inhibit Glioblastoma Growth

(2016) G. Salzano et al.   Journal of Biomedical Nanotechnology

Infra Red Dye and Endostar Loaded Poly Lactic Acid Nano Particles as a Novel Theranostic Nanomedicine for Breast Cancer

(2016) Qian Zhang et al.   Journal of Biomedical Nanotechnology

Dendritic cell–derived exosomes for cancer therapy

(2016) Jonathan M. Pitt et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of chronic inflammatory and immune processes by extracellular vesicles

(2016) Paul D. Robbins et al.   JOURNAL OF CLINICAL INVESTIGATION

In vitro potency, in vitro and in vivo efficacy of liposomal alendronate in combination with γδ T cell immunotherapy in mice

(2016) Naomi O. Hodgins et al.   JOURNAL OF CONTROLLED RELEASE

PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time

(2016) S.A.A. Kooijmans et al.   JOURNAL OF CONTROLLED RELEASE

Coencapsulation of alendronate and doxorubicin in pegylated liposomes: a novel formulation for chemoimmunotherapy of cancer

(2016) Hilary Shmeeda et al.   JOURNAL OF DRUG TARGETING

A Retrospective 30 Years After Discovery of the Enhanced Permeability and Retention Effect of Solid Tumors: Next-Generation Chemotherapeutics and Photodynamic Therapy-Problems, Solutions, and Prospects

(2016) Hiroshi Maeda et al.   MICROCIRCULATION

Combining Stimulus-Triggered Release and Active Targeting Strategies Improves Cytotoxicity of Cytochrome c Nanoparticles in Tumor Cells

(2016) Moraima Morales-Cruz et al.   MOLECULAR PHARMACEUTICS

Spherical polymeric nanoconstructs for combined chemotherapeutic and anti-inflammatory therapies

(2016) Aeju Lee et al.   Nanomedicine-Nanotechnology Biology and Medicine

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

(2016) Joanna Kopecka et al.   Oncotarget

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

(2016) Hongyun Zhao et al.   eLife

Towards Therapeutic Delivery of Extracellular Vesicles: Strategies forIn VivoTracking and Biodistribution Analysis

(2016) Giuliana Di Rocco et al.   Stem Cells International

Recombinant human granulocyte macrophage colony stimulating factor (hGM-CSF): Possibility of nanoparticle-mediated delivery in cancer immunotherapy

(2016) Selvarajan Vanitha et al.   Bioengineered

Effect of the Polymer Architecture on the Structural and Biophysical Properties of PEG–PLA Nanoparticles

(2015) Jean-Michel Rabanel et al.   ACS Applied Materials & Interfaces

A CD44 specific peptide developed by phage display for targeting gastric cancer

(2015) Dan Zhang et al.   BIOTECHNOLOGY LETTERS

Applications of nanoparticles for diagnosis and therapy of cancer

(2015) S C Baetke et al.   BRITISH JOURNAL OF RADIOLOGY

The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy

(2015) Mateusz Legut et al.   Cellular & Molecular Immunology

Management of severe osteoporosis

(2015) Paul D. Miller   EXPERT OPINION ON PHARMACOTHERAPY

Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse

(2015) Sarah E. Church et al.   IMMUNITY

TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions

(2015) Peter J. Noy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells

(2015) Heikki Saari et al.   JOURNAL OF CONTROLLED RELEASE

Aqueous Solutions of Poly(ethylene oxide)-Poly(N-isopropylacrylamide): Thermosensitive Behavior and Distinct Multiple Assembly Processes

(2015) Qiuwen Wang et al.   LANGMUIR

Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes

(2015) Henriette Ebsen et al.   MOLECULAR IMMUNOLOGY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

(2015) Charles P. Lai et al.   Nature Communications

γδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy?

(2015) Jaydeep Bhat et al.   OncoImmunology

ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing

(2015) Maria Raffaella Zocchi et al.   OncoImmunology

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid

(2015) Manuela Porru et al.   Oncotarget

Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients

(2015) Corinna Eichelser et al.   Oncotarget

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

(2014) Charles P. Lai et al.   ACS Nano

Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration

(2014) Keisuke Shimbo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fluorinated poly(propylenimine) dendrimers as gene vectors

(2014) Hongmei Liu et al.   BIOMATERIALS

Nanoparticles for the delivery of zoledronic acid to prostate cancer cells: A comparative analysis through time lapse video-microscopy technique

(2014) Chiara Schiraldi et al.   CANCER BIOLOGY & THERAPY

A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer

(2014) Hee Kyung Ahn et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Mechanisms of tumor escape from immune system: Role of mesenchymal stromal cells

(2014) Alessandro Poggi et al.   IMMUNOLOGY LETTERS

Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery

(2014) Luisa Pascucci et al.   JOURNAL OF CONTROLLED RELEASE

Adoptive Immunotherapy of Epithelial Ovarian Cancer with Vγ9Vδ2 T Cells, Potentiated by Liposomal Alendronic Acid

(2014) Ana C. Parente-Pereira et al.   JOURNAL OF IMMUNOLOGY

Emerging applications for ferumoxytol as a contrast agent in MRI

(2014) Mustafa R. Bashir et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Adjuvant zoledronic acid in patients with early breast cancer: final efficacy analysis of the AZURE (BIG 01/04) randomised open-label phase 3 trial

(2014) Robert Coleman et al.   LANCET ONCOLOGY

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment

(2014) Ze Liu et al.   Nature Communications

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth

(2013) Mark Katakowski et al.   CANCER LETTERS

Doxorubicin loading fucoidan acetate nanoparticles for immune and chemotherapy in cancer treatment

(2013) Kun Woo Lee et al.   CARBOHYDRATE POLYMERS

P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives

(2013) Ziyad Binkhathlan et al.   CURRENT CANCER DRUG TARGETS

Aminobisphosphonates prevent the inhibitory effects exerted by lymph node stromal cells on anti-tumor V  2 T lymphocytes in non-Hodgkin lymphomas

(2013) A. Musso et al.   HAEMATOLOGICA

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

(2013) Aldo M. Roccaro et al.   JOURNAL OF CLINICAL INVESTIGATION

Liposome encapsulation of zoledronic acid results in major changes in tissue distribution and increase in toxicity

(2013) Hilary Shmeeda et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticles and the blood coagulation system. Part II: safety concerns

(2013) Anna N Ilinskaya et al.   Nanomedicine

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

(2013) Stefano Vavassori et al.   NATURE IMMUNOLOGY

Dendrimer as nanocarrier for drug delivery

(2013) Prashant Kesharwani et al.   PROGRESS IN POLYMER SCIENCE

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

CD44-Targeting for Antitumor Drug Delivery: A New SN-38-Hyaluronan Bioconjugate for Locoregional Treatment of Peritoneal Carcinomatosis

(2012) A. Serafino et al.   CURRENT CANCER DRUG TARGETS

Combinatorial Nanoparticles for Cancer Diagnosis and Therapy

(2012) A. Mukerjee et al.   CURRENT MEDICINAL CHEMISTRY

Self-assembling nanoparticles for the release of bisphosphonates in the treatment of human cancers [WO2012042024]

(2012) Jingxin Gou et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications

(2012) Ganesh Venkatraman et al.   International Journal of Nanomedicine

Blood–Nanoparticle Interactions and in Vivo Biodistribution: Impact of Surface PEG and Ligand Properties

(2012) Neha B. Shah et al.   MOLECULAR PHARMACEUTICS

Nanotechnology in Cancer Medicine

(2012) Jennifer H. Grossman et al.   PHYSICS TODAY

Microvesicles Derived from Human Bone Marrow Mesenchymal Stem Cells Inhibit Tumor Growth

(2012) Stefania Bruno et al.   STEM CELLS AND DEVELOPMENT

Delivery of chemotherapeutic drugs in tumour cell-derived microparticles

(2012) Ke Tang et al.   Nature Communications

Nanomedicine for Cancer: Lipid-Based Nanostructures for Drug Delivery and Monitoring

(2011) Yoshihisa Namiki et al.   ACCOUNTS OF CHEMICAL RESEARCH

New self-assembly nanoparticles and stealth liposomes for the delivery of zoledronic acid: a comparative study

(2011) Monica Marra et al.   BIOTECHNOLOGY ADVANCES

Applications of advanced hybrid organic–inorganic nanomaterials: from laboratory to market

(2011) Clément Sanchez et al.   CHEMICAL SOCIETY REVIEWS

Self-Assembling Peptides: Potential Role in Tumor Targeting

(2011) Parisa Sadatmousavi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

(2011) Miriam Benezra et al.   JOURNAL OF CLINICAL INVESTIGATION

Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression

(2011) Stefania Nobili et al.   MEDICINAL RESEARCH REVIEWS

Nanotechnologies to use bisphosphonates as potent anticancer agents: the effects of zoledronic acid encapsulated into liposomes

(2011) Monica Marra et al.   Nanomedicine-Nanotechnology Biology and Medicine

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3

(2011) T. Aung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging and drug delivery using theranostic nanoparticles

(2010) Siti M. Janib et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor delivery of macromolecular drugs based on the EPR effect

(2010) Vladimir Torchilin   ADVANCED DRUG DELIVERY REVIEWS

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine

(2010) S. K. Libutti et al.   CLINICAL CANCER RESEARCH

Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

(2010) F. Peter Guengerich   Drug Metabolism and Pharmacokinetics

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer

(2010) Silverio Tomao   International Journal of Nanomedicine

Self-assembly nanoparticles for the delivery of bisphosphonates into tumors

(2010) G. Salzano et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

CD23 Sheddase A Disintegrin and Metalloproteinase 10 (ADAM10) Is Also Required for CD23 Sorting into B Cell-derived Exosomes

(2010) Joel A. Mathews et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delivery of zoledronic acid encapsulated in folate-targeted liposome results in potent in vitro cytotoxic activity on tumor cells

(2010) Hilary Shmeeda et al.   JOURNAL OF CONTROLLED RELEASE

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

Multicompartment vectors as novel drug delivery systems: selective activation of Tγδ lymphocytes after zoledronic acid delivery

(2010) Chiara Agrati et al.   Nanomedicine-Nanotechnology Biology and Medicine

Small-molecule delivery by nanoparticles for anticancer therapy

(2010) Zhuo (Georgia) Chen   TRENDS IN MOLECULAR MEDICINE

Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer

(2009) Seymour   INTERNATIONAL JOURNAL OF ONCOLOGY

Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone

(2009) P. D. Ottewell et al.   MOLECULAR CANCER THERAPEUTICS

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

(2009) K. Al-Nedawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Inhibition with a Dual Epidermal Growth Factor Receptor/HER-2/neu Tyrosine Kinase Inhibitor and a Disintegrin and Metalloprotease Inhibitor

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