Synthesis and in vitro Evaluation of ADAM10 and ADAM17 Highly Selective Bioimaging Probes

Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells

(2018) Francesca Tosetti et al.   OncoImmunology

Properties of in situ generated gold nanoparticles in the cellular context

(2017) D. Drescher et al.   Nanoscale

Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes

(2016) Thomas Bordenave et al.   BIOCONJUGATE CHEMISTRY

Targeting ADAM17 Sheddase Activity in Cancer

(2016) Armando Rossello et al.   CURRENT DRUG TARGETS

Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models

(2016) Caterina Camodeca et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke

(2016) Shanyan Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids

(2016) Alexandra L. Matthews et al.   PLATELETS

Efficient delivery of C/EBP beta gene into human mesenchymal stem cells via polyethylenimine-coated gold nanoparticles enhances adipogenic differentiation

(2016) Joydeep Das et al.   Scientific Reports

Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate

(2016) Franck Madoux et al.   Scientific Reports

Control of ADAM17 activity by regulation of its cellular localisation

(2016) Inken Lorenzen et al.   Scientific Reports

Fluorescent Analogue of Batimastat Enables Imaging of α-Secretase in Living Cells

(2015) Geoffray Leriche et al.   ACS Chemical Neuroscience

Synthesis of tumor-associated MUC1-glycopeptides and their multivalent presentation by functionalized gold colloids

(2015) Isabella Tavernaro et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing

(2015) Maria Raffaella Zocchi et al.   OncoImmunology

In Situ Determination of Colloidal Gold Concentrations with UV–Vis Spectroscopy: Limitations and Perspectives

(2014) Thomas Hendel et al.   ANALYTICAL CHEMISTRY

pH-Responsive Assembly of Gold Nanoparticles and “Spatiotemporally Concerted” Drug Release for Synergistic Cancer Therapy

(2013) Jutaek Nam et al.   ACS Nano

Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models

(2013) Elisa Nuti et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Vivo Imaging of Matrix Metalloproteinase 12 and Matrix Metalloproteinase 13 Activities in the Mouse Model of Collagen-Induced Arthritis

(2013) Ngee Han Lim et al.   Arthritis & Rheumatology

Stability of antibody-conjugated gold nanoparticles in the endolysosomal nanoenvironment: implications for noninvasive radiofrequency-based cancer therapy

(2012) Mustafa Raoof et al.   Nanomedicine-Nanotechnology Biology and Medicine

Modulating enzymatic activity in the presence of gold nanoparticles

(2012) Jashmini Deka et al.   RSC Advances

High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas

(2011) M. R. Zocchi et al.   BLOOD

Size-dependent endocytosis of gold nanoparticles studied by three-dimensional mapping of plasmonic scattering images

(2011) Sheng-Hann Wang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-α Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models

(2010) Elisa Nuti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Evaluation of a Novel Hydroxamate Based Fluorescent Photoprobe for Imaging of Matrix Metalloproteinases

(2009) Andreas Faust et al.   BIOCONJUGATE CHEMISTRY

Tamoxifen−Poly(ethylene glycol)−Thiol Gold Nanoparticle Conjugates: Enhanced Potency and Selective Delivery for Breast Cancer Treatment

(2009) Erik C. Dreaden et al.   BIOCONJUGATE CHEMISTRY

The role of ADAMs in disease pathophysiology

(2009) Michael J. Duffy et al.   CLINICA CHIMICA ACTA

Developments in fluorescent probes for receptor research

(2009) Marcello Leopoldo et al.   DRUG DISCOVERY TODAY

In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

(2009) Emilia S. Olson et al.   Integrative Biology

Regulation of Enzyme Activity through Interactions with Nanoparticles

(2009) Zhaochun Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Applications of Nanoparticles in Biology

(2008) Mrinmoy De et al.   ADVANCED MATERIALS

Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme

(2008) Cristina Escrevente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Tumor-Associated MICA Is Shed by ADAM Proteases

(2008) I. Waldhauer et al.   CANCER RESEARCH

Fluorescent probes for bioimaging applications

(2008) Takuya Terai et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

ADAM10 as a Target for Anti-Cancer Therapy

(2008) Marcia Moss et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions

(2008) Karina Reiss et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY