The biology of extracellular vesicles: The known unknowns

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

(2019) Saumya Das et al.   CELL

Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation

(2019) Srimeenakshi Srinivasan et al.   CELL

PKH26 labeling of extracellular vesicles: Characterization and cellular internalization of contaminating PKH26 nanoparticles

(2018) Pia Pužar Dominkuš et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mechanism of recipient cell-dependent differences in exosome uptake

(2018) Sayo Horibe et al.   BMC CANCER

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

(2018) Haiying Zhang et al.   NATURE CELL BIOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs

(2018) Sukhbir Kaur et al.   Scientific Reports

A System of Cytokines Encapsulated in ExtraCellular Vesicles

(2018) Wendy Fitzgerald et al.   Scientific Reports

Circulating Extracellular Vesicles in Human Disease

(2018) Ravi Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human cytomegalovirus-infected cells release extracellular vesicles that carry viral surface proteins

(2018) Sonia Zicari et al.   VIROLOGY

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

150 years of Darwin’s theory of intercellular flow of hereditary information

(2018) Yongsheng Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation

(2018) Ni-Ting Chiou et al.   Cell Reports

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

(2017) Yalin Zhang et al.   NATURE

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

(2017) Jan Van Deun et al.   NATURE METHODS

Viral effects on the content and function of extracellular vesicles

(2017) Nancy Raab-Traub et al.   NATURE REVIEWS MICROBIOLOGY

Formation and size distribution of self-assembled vesicles

(2017) Changjin Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

(2017) Matthew J. Shurtleff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of exosomes from whole blood by integrating acoustics and microfluidics

(2017) Mengxi Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipids in exosomes: Current knowledge and the way forward

(2017) Tore Skotland et al.   PROGRESS IN LIPID RESEARCH

Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed?

(2017) V R Minciacchi et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue

(2017) Anush Arakelyan et al.   Scientific Reports

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture

(2017) Zhaohao Liao et al.   Scientific Reports

Reversible HuR‐microRNA binding controls extracellular export of miR‐122 and augments stress response

(2016) Kamalika Mukherjee et al.   EMBO REPORTS

Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

(2016) Wolf Heusermann et al.   JOURNAL OF CELL BIOLOGY

Extracellular vesicles and viruses: Are they close relatives?

(2016) Esther Nolte-‘t Hoen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting

(2016) Laura Santangelo et al.   Cell Reports

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

(2016) Matthew J Shurtleff et al.   eLife

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction

(2015) M. Khan et al.   CIRCULATION RESEARCH

A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes

(2015) Linmao Lyu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines

(2015) J. P. Tosar et al.   NUCLEIC ACIDS RESEARCH

Gram-negative and Gram-positive bacterial extracellular vesicles

(2015) Ji Hyun Kim et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

KRAS-dependent sorting of miRNA to exosomes

(2015) Diana J Cha et al.   eLife

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

(2015) Kirsten Ridder et al.   OncoImmunology

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

The Neutral Sphingomyelinase Pathway Regulates Packaging of the Prion Protein into Exosomes

(2014) Belinda B. Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of Cytokines With Exosomes in the Plasma of HIV-1–Seropositive Individuals

(2014) Kateena Addae Konadu et al.   JOURNAL OF INFECTIOUS DISEASES

Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration

(2014) N. Arraud et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

(2014) Terence N. Bukong et al.   PLoS Pathogens

Review: Placenta-specific microRNAs in exosomes – Good things come in nano-packages

(2013) Y. Ouyang et al.   PLACENTA

Human placental trophoblasts confer viral resistance to recipient cells

(2013) E. Delorme-Axford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

(2013) V. Ramakrishnaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

(2012) Dolores Di Vizio et al.   AMERICAN JOURNAL OF PATHOLOGY

The expression profile of C19MC microRNAs in primary human trophoblast cells and exosomes

(2012) R. B. Donker et al.   MOLECULAR HUMAN REPRODUCTION

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

Perspectives on Kiss-and-Run: Role in Exocytosis, Endocytosis, and Neurotransmission

(2011) AbdulRasheed A. Alabi et al.   Annual Review of Physiology

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY