ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing

Effect of NKG2D ligand expression on host immune responses

(2015) Marine Champsaur et al.   IMMUNOLOGICAL REVIEWS

Expression of tumour necrosis factor-α and its receptors in Hodgkin lymphoma

(2014) Shoko Nakayama et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer

(2014) Achilleas D. Theocharis et al.   FEBS Journal

Aminobisphosphonates prevent the inhibitory effects exerted by lymph node stromal cells on anti-tumor V  2 T lymphocytes in non-Hodgkin lymphomas

(2013) A. Musso et al.   HAEMATOLOGICA

Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: Heterogeneous involvement of the “a disintegrin and metalloproteases” 10 and 17

(2013) Guranda Chitadze et al.   INTERNATIONAL JOURNAL OF CANCER

Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models

(2013) Elisa Nuti et al.   JOURNAL OF MEDICINAL CHEMISTRY

High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas

(2011) M. R. Zocchi et al.   BLOOD

The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

(2010) Paul Saftig et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Differential survival of γδT cells, αβT cells and NK cells upon engagement of NKG2D by NKG2DL-expressing leukemic cells

(2010) Alessandro Poggi et al.   INTERNATIONAL JOURNAL OF CANCER

Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-α Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models

(2010) Elisa Nuti et al.   JOURNAL OF MEDICINAL CHEMISTRY

The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia

(2010) H Nückel et al.   LEUKEMIA

γδ T Cells and the Lymphoid Stress-Surveillance Response

(2009) Adrian C. Hayday   IMMUNITY

Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate

(2009) A Poggi et al.   LEUKEMIA

Synergistic Inhibition with a Dual Epidermal Growth Factor Receptor/HER-2/neu Tyrosine Kinase Inhibitor and a Disintegrin and Metalloprotease Inhibitor

(2008) L. Witters et al.   CANCER RESEARCH

Tumor-Associated MICA Is Shed by ADAM Proteases

(2008) I. Waldhauer et al.   CANCER RESEARCH

ADAM10 as a Target for Anti-Cancer Therapy

(2008) Marcia Moss et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

NKG2D ligands in tumor immunity

(2008) N Nausch et al.   ONCOGENE

MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma

(2008) M. Jinushi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of ADAM and ADAMTS metalloproteinases in cancer

(2007) N. Rocks et al.   BIOCHIMIE